Development Level

Tbio 31 | 11,178
Tchem 10 | 1,885
Tclin 8 | 612
Tdark 7 | 6,569

IMPC Phenotype

increased total body fat amoun... 4 | 134
abnormal behavior 3 | 298
decreased bone mineral content 3 | 151
decreased lean body mass 3 | 135
hypoactivity 3 | 132
preweaning lethality, complete... 3 | 979
abnormal bone structure 2 | 187
abnormal male genitalia morpho... 2 | 3
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral density 2 | 126
decreased heart weight 2 | 27
improved glucose tolerance 2 | 79
preweaning lethality, incomple... 2 | 499
small kidney 2 | 16
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal kidney morphology 1 | 65
abnormal ovary morphology 1 | 7
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
absent epididymis 1 | 3
absent external male genitalia 1 | 1
absent ovary 1 | 3
absent seminal vesicle 1 | 4
absent startle reflex 1 | 24
absent testes 1 | 6
absent uterus 1 | 1
decreased body weight 1 | 161
decreased brain size 1 | 4
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased heart rate 1 | 18
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
fusion of vertebral arches 1 | 7
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
oligodactyly 1 | 1
polydactyly 1 | 7
polysyndactyly 1 | 2
prolonged RR interval 1 | 8
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small superior vagus ganglion 1 | 74
small thymus 1 | 16
vertebral transformation 1 | 12

Disease

Amenorrhea 56 | 56
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 53 | 18,159
Female tissues 49 | 17,400
Skin and soft tissues 48 | 17,230
Digestive Tract 47 | 17,369
Nervous System 47 | 16,725
Blood and immune system 44 | 16,909
Liver and Pancreas 44 | 16,750
Male tissues 43 | 17,142
Respiratory system 41 | 16,393
Urinary Tract 38 | 16,678
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 32 | 12,091
Enzyme 8 | 4,145
GPCR 7 | 408
Transcription Factor 5 | 1,400
Nuclear Receptor 2 | 48
Epigenetic 1 | 242
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pro-thyrotropin-releasing hormone TRH Tbio Non-IDG -3.25312 1828.2 102
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369
Homologous-pairing protein 2 homolog PSMC3IP Tbio Non-IDG -0.97122 14.2 48
Progesterone receptor PGR Tclin Nuclear Receptor -3.94412 7951.2 2098
Zinc finger protein 205 ZNF205 Tbio Transcription Factor -0.19189 1.48 88
Carboxypeptidase B2 CPB2 Tchem Enzyme -2.74770 659.0 375
Guanylate-binding protein 4 GBP4 Tbio Non-IDG -1.68193 45.8 122
Homeobox protein NOBOX NOBOX Tbio Transcription Factor -1.72297 50.9 87
NADPH--cytochrome P450 reductase POR Tchem Enzyme -2.43541 216.2 257
Chorionic somatomammotropin hormone 2 CSH2 Tbio Non-IDG -2.95755 830.6 89