Development Level

Tbio 36 | 11,445
Tclin 8 | 613
Tchem 7 | 1,598
Tdark 7 | 6,588

IMPC Phenotype

increased total body fat amoun... 4 | 134
abnormal behavior 3 | 298
decreased bone mineral content 3 | 151
decreased lean body mass 3 | 135
hypoactivity 3 | 132
preweaning lethality, complete... 3 | 979
abnormal bone structure 2 | 187
abnormal male genitalia morpho... 2 | 3
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral density 2 | 126
decreased heart weight 2 | 27
improved glucose tolerance 2 | 79
preweaning lethality, incomple... 2 | 499
small kidney 2 | 16
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal kidney morphology 1 | 65
abnormal ovary morphology 1 | 7
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
absent epididymis 1 | 3
absent external male genitalia 1 | 1
absent ovary 1 | 3
absent seminal vesicle 1 | 4
absent startle reflex 1 | 24
absent testes 1 | 6
absent uterus 1 | 1
decreased body weight 1 | 161
decreased brain size 1 | 4
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased heart rate 1 | 18
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
fusion of vertebral arches 1 | 7
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
oligodactyly 1 | 1
polydactyly 1 | 7
polysyndactyly 1 | 2
prolonged RR interval 1 | 8
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small superior vagus ganglion 1 | 74
small thymus 1 | 16
vertebral transformation 1 | 12

Disease

Amenorrhea 58 | 58
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 55 | 18,159
Female tissues 50 | 17,400
Skin and soft tissues 50 | 17,230
Digestive Tract 49 | 17,369
Nervous System 48 | 16,725
Blood and immune system 45 | 16,909
Male tissues 45 | 17,142
Liver and Pancreas 44 | 16,750
Respiratory system 43 | 16,393
Urinary Tract 38 | 16,678
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 32 | 12,091
Enzyme 8 | 4,145
GPCR 7 | 408
Transcription Factor 6 | 1,400
Nuclear Receptor 3 | 48
Epigenetic 1 | 242
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
NADPH--cytochrome P450 reductase POR Tbio Enzyme -2.43541 216.2 257
Chorionic somatomammotropin hormone 2 CSH2 Tbio Non-IDG -2.95755 830.6 89
Guanylate-binding protein 4 GBP4 Tbio Non-IDG -1.68193 45.8 122
Nuclear receptor subfamily 0 group B member 1 NR0B1 Tbio Nuclear Receptor -2.73235 544.8 477
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.43406 2729.3 264
Olfactory receptor 1F1 OR1F1 Tdark oGPCR 0.77 0.15 56
Ret finger protein-like 4A RFPL4A Tdark Non-IDG -0.25795 2.62 59
Four and a half LIM domains protein 2 FHL2 Tbio Non-IDG -2.60042 385.8 253
Carboxypeptidase B2 CPB2 Tchem Enzyme -2.74770 659.0 375