Development Level

Tbio 74 | 11,651
Tchem 18 | 1,388
Tclin 5 | 612
Tdark 2 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
decreased grip strength 3 | 116
decreased startle reflex 3 | 75
decreased vertical activity 3 | 208
hypoactivity 3 | 132
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
increased body weight 2 | 25
mydriasis 2 | 6
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal duodenum morphology 1 | 4
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
cataract 1 | 92
corneal opacity 1 | 32
decreased basophil cell number 1 | 16
decreased body temperature 1 | 2
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
prenatal lethality prior to he... 1 | 87
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
small heart 1 | 10
vertebral transformation 1 | 12

Disease

Adenoid Cystic Carcinoma 99 | 99
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 98 | 18,159
Female tissues 98 | 17,400
Skin and soft tissues 97 | 17,230
Digestive Tract 96 | 17,369
Nervous System 96 | 16,725
Blood and immune system 95 | 16,909
Male tissues 95 | 17,142
Urinary Tract 94 | 16,678
Respiratory system 93 | 16,393
Liver and Pancreas 92 | 16,750
Cardiovascular System 91 | 15,192

Target Family

Non-IDG 43 | 12,091
Transcription Factor 17 | 1,400
Enzyme 14 | 4,145
Epigenetic 13 | 242
Kinase 9 | 634
Ion Channel 1 | 344
TF/Epigenetic 1 | 38
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific NSD1 Tbio Epigenetic -2.16239 142.5 123
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 ST3GAL4 Tbio Enzyme -2.19681 149.3 89
E3 ubiquitin-protein ligase UHRF1 UHRF1 Tbio Epigenetic 0.00000 279
RNA binding protein fox-1 homolog 2 RBFOX2 Tbio Non-IDG -1.85048 66.2 178
Denticleless protein homolog DTL Tbio Non-IDG -1.63065 50.0 160
Erbin ERBIN Tbio Non-IDG -1.72357 59.1 117
Zinc finger imprinted 2 ZIM2 Tdark Transcription Factor -0.68369 3.42 68
Breast cancer type 1 susceptibility protein BRCA1 Tchem Non-IDG -3.76784 6081.3 1542
Protein jagged-1 JAG1 Tbio Non-IDG -3.09216 1190.8 473
X antigen family member 1 XAGE1A Tbio Non-IDG 0.00000 58