Development Level

Tbio 98 | 11,445
Tchem 28 | 1,598
Tclin 12 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 18 | 979
embryonic lethality prior to o... 6 | 239
decreased total body fat amoun... 5 | 207
preweaning lethality, incomple... 4 | 499
abnormal sleep behavior 3 | 70
decreased body weight 3 | 161
decreased circulating glucose ... 3 | 126
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
shortened RR interval 3 | 17
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal retina morphology 2 | 71
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased lean body mass 2 | 135
enlarged heart 2 | 210
increased body length 2 | 32
increased bone mineral content 2 | 108
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
thrombocytopenia 2 | 56
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal spinal cord morpholog... 1 | 9
abnormal spine curvature 1 | 9
abnormal tibia morphology 1 | 14
abnormal vitreous body morphol... 1 | 10
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
cataract 1 | 92
decreased IgG1 level 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased granulocyte number 1 | 6
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
hypoactivity 1 | 132
increased body temperature 1 | 9
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased heart rate 1 | 23
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
long tibia 1 | 25
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97

Disease

Adenocarcinoma of lung 142 | 142
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 142 | 18,159
Female tissues 142 | 17,400
Digestive Tract 141 | 17,369
Respiratory system 141 | 16,393
Skin and soft tissues 141 | 17,230
Urinary Tract 141 | 16,678
Blood and immune system 140 | 16,909
Liver and Pancreas 140 | 16,750
Male tissues 140 | 17,142
Nervous System 140 | 16,725
Cardiovascular System 139 | 15,192

Target Family

Non-IDG 66 | 12,091
Enzyme 43 | 4,145
Kinase 13 | 634
Transcription Factor 11 | 1,400
Epigenetic 4 | 242
Transporter 4 | 473
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Electrogenic sodium bicarbonate cotransporter 1 SLC4A4 Tbio Transporter -2.63743 436.2 124
Delta-1-pyrroline-5-carboxylate synthase ALDH18A1 Tbio Enzyme -2.34260 216.5 146
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Nucleolar protein 58 NOP58 Tbio Non-IDG -1.46442 30.0 85
Translation initiation factor eIF-2B subunit delta EIF2B4 Tbio Non-IDG -1.06082 11.3 145
Folate transporter 1 SLC19A1 Tchem Transporter -2.00363 97.7 67
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Serum albumin ALB Tchem Non-IDG -5.01233 98804.9 2101
Hexokinase-2 HK2 Tchem Kinase -2.64934 432.5 446