Development Level

Tbio 32 | 11,445
Tclin 10 | 613
Tchem 9 | 1,598

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal bone structure 5 | 187
increased heart weight 4 | 62
increased startle reflex 4 | 112
increased total body fat amoun... 4 | 134
decreased lean body mass 3 | 135
enlarged heart 3 | 210
abnormal heart morphology 2 | 162
abnormal lung morphology 2 | 26
decreased bone mineral content 2 | 151
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased respiratory quotient 1 | 16
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
prolonged RR interval 1 | 8
short tibia 1 | 97
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Acromegaly 51 | 51
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 46 | 18,159
Digestive Tract 45 | 17,369
Female tissues 45 | 17,400
Nervous System 44 | 16,725
Respiratory system 41 | 16,393
Skin and soft tissues 40 | 17,230
Blood and immune system 39 | 16,909
Male tissues 38 | 17,142
Liver and Pancreas 37 | 16,750
Urinary Tract 35 | 16,678
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 30 | 12,091
GPCR 11 | 408
Enzyme 6 | 4,145
Kinase 1 | 634
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.14265 126.2 303
Somatostatin receptor type 2 SSTR2 Tclin GPCR -2.53936 363.5 246
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Somatostatin SST Tbio Non-IDG -4.14886 13572.0 397
5-hydroxytryptamine receptor 6 HTR6 Tchem GPCR -2.31880 213.2 64
Saitohin STH Tbio Non-IDG -2.85999 730.0 42
Probable G-protein coupled receptor 101 GPR101 Tbio GPCR -1.13310 16.7 157
Somatostatin receptor type 5 SSTR5 Tclin GPCR -2.10658 120.8 191
Protein ALEX GNAS Tbio Non-IDG -2.63356 1389.7 509
Somatostatin receptor type 3 SSTR3 Tclin GPCR -1.89900 68.6 106