Development Level

Tbio 29 | 11,178
Tchem 13 | 1,885
Tclin 7 | 612

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 2 | 298
embryonic lethality prior to o... 2 | 239
hydrometra 2 | 53
hyperactivity 2 | 148
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
abnormal cecum morphology 1 | 7
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal male genitalia morpho... 1 | 3
abnormal retinal vasculature m... 1 | 27
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
decreased body weight 1 | 161
decreased brain size 1 | 4
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased pulmonary respirator... 1 | 5
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
fusion of vertebral arches 1 | 7
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased eosinophil cell numb... 1 | 11
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
polysyndactyly 1 | 2
short tibia 1 | 97
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small testis 1 | 58
small thymus 1 | 16
thrombocytopenia 1 | 56
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Acne 49 | 49
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Digestive Tract 48 | 17,369
Skin and soft tissues 47 | 17,230
Blood and immune system 46 | 16,909
Female tissues 46 | 17,400
Liver and Pancreas 46 | 16,750
Male tissues 46 | 17,142
Endocrine System 45 | 18,159
Respiratory system 45 | 16,393
Urinary Tract 45 | 16,678
Nervous System 44 | 16,725
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 28 | 12,091
Enzyme 9 | 4,145
Transcription Factor 4 | 1,400
GPCR 2 | 408
Kinase 2 | 634
Nuclear Receptor 2 | 48
Epigenetic 1 | 242
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dermcidin DCD Tbio Non-IDG -2.24062 182.4 128
Adenylosuccinate lyase ADSL Tbio Enzyme -3.32293 2023.8 144
GDH/6PGL endoplasmic bifunctional protein H6PD Tbio Non-IDG -2.24806 169.7 207
Beta-defensin 104 DEFB104B Tbio Non-IDG -1.60840 38.0 35
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Gamma-secretase subunit PEN-2 PSENEN Tchem Enzyme -2.84761 677.3 204
Pre-mRNA-splicing factor 38A PRPF38A Tbio Non-IDG -0.73373 5.30 81
Proline-serine-threonine phosphatase-interacting protein 1 PSTPIP1 Tbio Enzyme -1.89883 82.3 119
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Alanine--tRNA ligase, cytoplasmic AARS Tbio Enzyme -2.49617 295.2 140