Development Level

Tbio 35 | 11,651
Tchem 10 | 1,388
Tclin 7 | 612

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 2 | 298
embryonic lethality prior to o... 2 | 239
hydrometra 2 | 53
hyperactivity 2 | 148
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
abnormal cecum morphology 1 | 7
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal male genitalia morpho... 1 | 3
abnormal retinal vasculature m... 1 | 27
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
decreased body weight 1 | 161
decreased brain size 1 | 4
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased pulmonary respirator... 1 | 5
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
fusion of vertebral arches 1 | 7
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased eosinophil cell numb... 1 | 11
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
polysyndactyly 1 | 2
short tibia 1 | 97
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small testis 1 | 58
small thymus 1 | 16
thrombocytopenia 1 | 56
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Acne 52 | 52
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 51 | 17,369
Skin and soft tissues 50 | 17,230
Blood and immune system 49 | 16,909
Female tissues 49 | 17,400
Liver and Pancreas 49 | 16,750
Male tissues 49 | 17,142
Endocrine System 48 | 18,159
Respiratory system 48 | 16,393
Urinary Tract 48 | 16,678
Nervous System 47 | 16,725
Cardiovascular System 44 | 15,192

Target Family

Non-IDG 28 | 12,091
Enzyme 12 | 4,145
Transcription Factor 4 | 1,400
GPCR 2 | 408
Kinase 2 | 634
Nuclear Receptor 2 | 48
Epigenetic 1 | 242
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GDH/6PGL endoplasmic bifunctional protein H6PD Tbio Non-IDG -2.24806 169.7 207
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
cAMP-dependent protein kinase catalytic subunit alpha PRKACA Tchem Kinase -1.09531 11.7 331
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060
Endoplasmic reticulum aminopeptidase 1 ERAP1 Tchem Enzyme -2.32434 221.0 216
NKG2-F type II integral membrane protein KLRC4 Tbio Non-IDG -0.66244 5.20 40
Protein transport protein Sec24C SEC24C Tbio Non-IDG -0.97939 10.3 94
Signal transducer and activator of transcription 4 STAT4 Tbio Transcription Factor -2.51382 320.4 790
Interleukin-1 alpha IL1A Tchem Non-IDG -3.56722 3688.9 1000
Ubiquitin carboxyl-terminal hydrolase 8 USP8 Tbio Enzyme -1.72968 58.3 209