Development Level

Tbio 4,015 | 10,625
Tdark 1,101 | 7,003
Tchem 790 | 1,890
Tclin 226 | 602

Collection

Kinase: IDG Consortium (Targets) 54 | 125
Kinase: IDG Consortium (Complete/Control) 21 | 37
Ion Channel: IDG Consortium (Targets) 18 | 102
GPCR: IDG Consortium (Targets) 9 | 127
GPCR: IDG Consortium (Complete/Control) 1 | 26

IMPC Phenotype

preweaning lethality, complete... 285 | 633
preweaning lethality, incomple... 100 | 260
abnormal behavior 80 | 226
embryonic lethality prior to t... 80 | 187
decreased lean body mass 78 | 195
decreased total body fat amoun... 78 | 186
embryonic lethality prior to o... 75 | 148
decreased body weight 74 | 174
decreased bone mineral content 67 | 157
decreased bone mineral density 58 | 126
increased circulating alkaline... 56 | 119
abnormal bone structure 53 | 131
decreased grip strength 50 | 123
increased or absent threshold ... 50 | 128
decreased body length 48 | 108
decreased circulating glucose ... 44 | 121
abnormal embryo size 43 | 112
increased mean corpuscular hem... 43 | 93
enlarged heart 38 | 111
increased lean body mass 38 | 107
decreased circulating triglyce... 37 | 83
hyperactivity 37 | 108
decreased circulating choleste... 35 | 85
increased fasted circulating g... 35 | 68
increased bone mineral content 34 | 92
increased grip strength 34 | 83
short tibia 34 | 82
decreased circulating HDL chol... 33 | 77
abnormal retina morphology 32 | 100
decreased circulating serum al... 31 | 79
abnormal lens morphology 30 | 73
decreased mean corpuscular vol... 30 | 50
hypoactivity 27 | 89
male infertility 27 | 62
increased mean corpuscular vol... 26 | 91
abnormal sleep behavior 25 | 63
decreased circulating insulin ... 25 | 75
impaired glucose tolerance 25 | 52
increased circulating choleste... 25 | 53
increased circulating sodium l... 25 | 71
prenatal lethality prior to he... 25 | 64
increased circulating HDL chol... 24 | 63
abnormal bone mineralization 23 | 55
abnormal retinal pigmentation 23 | 61
decreased lumbar vertebrae num... 23 | 62
decreased caudal vertebrae num... 22 | 49
decreased hemoglobin content 22 | 53
increased bone mineral density 22 | 52
decreased fasted circulating g... 21 | 49
decreased rib number 21 | 59
thrombocytopenia 21 | 46
abnormal coat-hair pigmentatio... 20 | 54
decreased circulating alanine ... 20 | 53
decreased startle reflex 20 | 48
increased exploration in new e... 20 | 56
increased leukocyte cell numbe... 20 | 37
increased sacral vertebrae num... 20 | 62
increased total body fat amoun... 20 | 57
abnormal gait 19 | 51
decreased heart weight 19 | 44
decreased prepulse inhibition 19 | 52
increased blood urea nitrogen ... 19 | 44
increased body weight 19 | 42
increased hemoglobin content 19 | 45
abnormal heart morphology 18 | 51
abnormal seminal vesicle morph... 18 | 47
decreased circulating alkaline... 18 | 41
decreased circulating fructosa... 18 | 31
decreased erythrocyte cell num... 18 | 43
decreased mean corpuscular hem... 18 | 34
improved glucose tolerance 18 | 56
decreased circulating chloride... 17 | 32
decreased circulating total pr... 17 | 41
decreased leukocyte cell numbe... 17 | 54
increased circulating chloride... 17 | 43
increased rib number 17 | 41
decreased circulating free fat... 16 | 39
increased circulating calcium ... 16 | 32
increased heart weight 16 | 37
abnormal behavioral response t... 15 | 52
abnormal eye morphology 15 | 38
abnormal testis morphology 15 | 30
increased circulating phosphat... 15 | 24
small testis 15 | 37
abnormal cranium morphology 14 | 32
abnormal epididymis morphology 14 | 31
abnormal spleen morphology 14 | 36
decreased NK T cell number 14 | 28
decreased blood urea nitrogen ... 14 | 31
decreased circulating LDL chol... 14 | 37
decreased circulating creatini... 14 | 31
decreased neutrophil cell numb... 14 | 37
increased hematocrit 14 | 36
increased startle reflex 14 | 38
abnormal neural tube closure 13 | 37
cardiovascular system phenotyp... 13 | 35
decreased circulating iron lev... 13 | 25
decreased effector memory CD8-... 13 | 24
increased circulating free fat... 13 | 17
increased erythrocyte cell num... 12 | 26

Disease

ovarian cancer 3,543 | 8,491
osteosarcoma 3,002 | 7,933
medulloblastoma, large-cell 2,317 | 6,234
psoriasis 2,303 | 6,685
glioblastoma 2,192 | 5,572
lung cancer 1,828 | 4,473
atypical teratoid / rhabdoid tumor 1,674 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 1,318 | 3,289
Breast cancer 1,212 | 3,098
malignant mesothelioma 1,210 | 3,163
pilocytic astrocytoma 1,163 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 1,146 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 1,113 | 2,956
invasive ductal carcinoma 1,104 | 2,950
primitive neuroectodermal tumor 1,088 | 3,031
oligodendroglioma 1,082 | 2,849
pediatric high grade glioma 1,046 | 2,712
non-small cell lung cancer 1,033 | 2,798
ependymoma 1,022 | 2,514
lung carcinoma 1,013 | 2,844
lung adenocarcinoma 983 | 2,714
pancreatic cancer 927 | 2,300
subependymal giant cell astrocytoma 927 | 2,287
Cancer 923 | 2,346
astrocytic glioma 869 | 2,241
Carcinoma 844 | 2,147
Multiple myeloma 841 | 1,327
pancreatic ductal adenocarcinoma liver metastasis 840 | 1,795
Pick disease 807 | 1,893
ulcerative colitis 796 | 2,087
adult high grade glioma 754 | 2,148
group 3 medulloblastoma 752 | 2,254
interstitial cystitis 749 | 2,299
group 4 medulloblastoma 716 | 1,875
astrocytoma 695 | 1,493
diabetes mellitus 667 | 1,663
tuberculosis 648 | 1,563
pituitary cancer 618 | 1,972
cystic fibrosis 601 | 1,670
ductal carcinoma in situ 598 | 1,745
breast carcinoma 589 | 1,614
medulloblastoma 583 | 1,524
acute quadriplegic myopathy 574 | 1,157
juvenile dermatomyositis 562 | 1,189
colon cancer 541 | 1,475
primary pancreatic ductal adenocarcinoma 538 | 1,271
sonic hedgehog group medulloblastoma 532 | 1,482
dermatomyositis 526 | 966
posterior fossa group A ependymoma 523 | 1,511
Waldenstrons macroglobulinemia 496 | 764
Rheumatoid Arthritis 492 | 1,170
adrenocortical carcinoma 485 | 1,427
posterior fossa group B ependymoma 441 | 1,530
spina bifida 384 | 1,064
atypical teratoid/rhabdoid tumor 373 | 1,095
cutaneous lupus erythematosus 367 | 1,056
nasopharyngeal carcinoma 354 | 1,056
non primary Sjogren syndrome sicca 353 | 840
active Crohn's disease 347 | 918
primary Sjogren syndrome 334 | 788
gastric carcinoma 328 | 832
acute myeloid leukemia 318 | 785
esophageal adenocarcinoma 309 | 737
Atopic dermatitis 303 | 944
progressive supranuclear palsy 302 | 674
Alzheimer's disease 291 | 644
Duchenne muscular dystrophy 290 | 602
tuberculosis and treatment for 6 months 290 | 686
pancreatic carcinoma 268 | 567
aldosterone-producing adenoma 261 | 664
Intellectual disability 250 | 573
Down syndrome 245 | 548
hepatocellular carcinoma 232 | 550
IGA Glomerulonephritis 225 | 454
autosomal dominant Emery-Dreifuss muscular dystrophy 223 | 499
Obesity 221 | 616
Neurodegenerative disease 215 | 383
Amyotrophic Lateral Sclerosis 212 | 432
mucosa-associated lymphoid tissue lymphoma 199 | 480
Prostatic Neoplasms 190 | 471
gastric cancer 190 | 436
hereditary spastic paraplegia 189 | 313
Mammary Neoplasms 176 | 410
Schizophrenia 171 | 503
fibroadenoma 167 | 557
Endometriosis 163 | 535
Parkinson's disease 155 | 364
Multiple Sclerosis 153 | 498
chronic rhinosinusitis 151 | 512
active ulcerative colitis 148 | 477
Kidney disease 145 | 397
Polycystic Ovary Syndrome 144 | 334
Stomach Neoplasms 143 | 282
non-small cell lung carcinoma 142 | 413
sarcoidosis 142 | 368
inflammatory breast cancer 139 | 404
Asthma 129 | 349
Vascular disease 128 | 281
Epilepsy 126 | 346
tuberculosis and treatment for 3 months 124 | 327

Tissue

Blood and immune system 6,132 | 17,994
Female tissues 6,119 | 18,646
Nervous System 6,113 | 18,560
Digestive Tract 6,112 | 18,472
Liver and Pancreas 6,109 | 18,135
Urinary Tract 6,107 | 18,443
Endocrine System 6,105 | 18,511
Male tissues 6,102 | 17,968
Cardiovascular System 6,092 | 17,957
Respiratory system 6,070 | 17,483
Skin and soft tissues 6,017 | 18,114

Target Family

Non-IDG 3,608 | 11,969
Enzyme 1,676 | 4,146
Kinase 356 | 634
Transcription Factor 156 | 1,400
Transporter 147 | 473
Ion Channel 70 | 341
Epigenetic 58 | 242
GPCR 37 | 408
oGPCR 12 | 421
TF/Epigenetic 8 | 38
Nuclear Receptor 4 | 48

HPM Tissue

Platelets 6,132 | 6,132
Adult Testis 10,842 | 10,842
Adult Ovary 10,200 | 10,200
Adult Retina 10,123 | 10,123
CD8 Cells 9,848 | 9,848
Fetal Heart 9,238 | 9,238
Adult Pancreas 9,174 | 9,174
Fetal Ovary 9,126 | 9,126
Adult Liver 9,121 | 9,121
B Cells 9,090 | 9,090
Adult Frontal Cortex 9,053 | 9,053
Adult Prostate 8,962 | 8,962
Fetal Gut 8,647 | 8,647
NK Cells 8,480 | 8,480
Adult Adrenal 8,478 | 8,478
Fetal Liver 8,409 | 8,409
Adult Rectum 8,031 | 8,031
Fetal Testis 7,960 | 7,960
Adult Colon 7,920 | 7,920
Fetal Brain 7,870 | 7,870
CD4 Cells 7,778 | 7,778
Adult Gallbladder 7,618 | 7,618
Adult Urinary Bladder 7,600 | 7,600
Adult Spinal Cord 7,598 | 7,598
Monocytes 7,426 | 7,426
Adult Kidney 6,727 | 6,727
Adult Lung 6,668 | 6,668
Adult Heart 6,509 | 6,509
Placenta 6,086 | 6,086
Adult Esophagus 4,938 | 4,938

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.50722 29.2 46
Epithelial membrane protein 3 EMP3 Tbio Non-IDG -1.64647 44.8 131
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.29669 19.6 50
Phosphoglycerate mutase 2 PGAM2 Tbio Enzyme -1.54638 36.2 160
Synapse differentiation-inducing gene protein 1-like SYNDIG1L Tdark Non-IDG -0.55764 3.83 4
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.04868 9.00 130
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
Protein Mpv17 MPV17 Tbio Non-IDG -1.63162 40.5 114
T-cell surface protein tactile CD96 Tbio Non-IDG -2.03517 108.7 142
Sorting nexin-32 SNX32 Tdark Non-IDG 0.60 0.07 75