Development Level

Tbio 6,340 | 11,651
Tdark 1,814 | 6,593
Tchem 780 | 1,388
Tclin 294 | 612

Collection

Kinase: IDG Consortium (Target... 73 | 125
Ion Channel: IDG Consortium (T... 27 | 99
Kinase: IDG Consortium (Comple... 25 | 37
GPCR: IDG Consortium (Targets) 11 | 126
GPCR: IDG Consortium (Complete... 4 | 25

IMPC Phenotype

preweaning lethality, complete... 708 | 979
preweaning lethality, incomple... 299 | 499
embryonic lethality prior to t... 196 | 278
embryonic lethality prior to o... 184 | 239
abnormal behavior 158 | 298
abnormal embryo size 148 | 220
decreased total body fat amoun... 113 | 207
enlarged heart 107 | 210
abnormal bone structure 102 | 187
decreased body weight 94 | 161
increased lean body mass 92 | 172
decreased vertical activity 87 | 208
decreased bone mineral content 84 | 151
hyperactivity 77 | 148
increased circulating alkaline... 77 | 122
abnormal heart morphology 76 | 162
embryonic growth retardation 76 | 106
hypoactivity 72 | 132
increased startle reflex 72 | 112
decreased circulating glucose ... 71 | 126
decreased bone mineral density 68 | 126
increased total body fat amoun... 64 | 134
male infertility 64 | 123
decreased grip strength 61 | 116
decreased lean body mass 60 | 135
short tibia 60 | 97
prenatal lethality prior to he... 59 | 87
increased mean corpuscular hem... 58 | 96
increased or absent threshold ... 58 | 101
increased bone mineral content 57 | 108
decreased body length 55 | 101
decreased circulating choleste... 54 | 93
cataract 53 | 92
abnormal lens morphology 51 | 81
abnormal seminal vesicle morph... 51 | 114
increased mean corpuscular vol... 50 | 92
decreased mean corpuscular vol... 49 | 79
decreased prepulse inhibition 48 | 82
abnormal retina morphology 46 | 71
decreased lymphocyte cell numb... 46 | 83
decreased circulating serum al... 45 | 82
decreased leukocyte cell numbe... 45 | 73
decreased startle reflex 43 | 75
increased fasted circulating g... 42 | 76
decreased circulating triglyce... 41 | 79
increased heart weight 41 | 62
abnormal gait 39 | 69
decreased circulating HDL chol... 39 | 68
impaired glucose tolerance 39 | 75
decreased circulating insulin ... 38 | 76
increased circulating HDL chol... 38 | 80
abnormal behavioral response t... 37 | 66
abnormal coat-hair pigmentatio... 37 | 64
abnormal eye morphology 37 | 68
edema 37 | 59
improved glucose tolerance 37 | 79
increased circulating choleste... 37 | 66
decreased erythrocyte cell num... 36 | 62
increased bone mineral density 36 | 72
small superior vagus ganglion 35 | 74
thrombocytopenia 35 | 56
decreased hemoglobin content 34 | 68
abnormal sleep behavior 33 | 70
decreased caudal vertebrae num... 33 | 53
decreased circulating total pr... 33 | 49
decreased fasted circulating g... 33 | 65
increased mean platelet volume 32 | 45
abnormal kidney morphology 31 | 65
increased circulating sodium l... 31 | 71
small testis 31 | 58
decreased circulating alkaline... 30 | 46
increased monocyte cell number 30 | 63
increased neutrophil cell numb... 30 | 46
decreased mean corpuscular hem... 29 | 50
increased hematocrit 29 | 46
abnormal skin morphology 28 | 50
female infertility 28 | 60
increased grip strength 28 | 41
increased leukocyte cell numbe... 28 | 47
decreased blood urea nitrogen ... 27 | 51
hydrometra 27 | 53
increased erythrocyte cell num... 27 | 39
increased hemoglobin content 27 | 45
tremors 27 | 39
abnormal neural tube closure 26 | 46
abnormal spleen morphology 26 | 55
decreased hematocrit 26 | 46
decreased neutrophil cell numb... 26 | 42
increased blood urea nitrogen ... 26 | 48
decreased circulating alanine ... 25 | 47
decreased red blood cell distr... 25 | 41
pallor 25 | 34
decreased circulating LDL chol... 24 | 38
decreased circulating calcium ... 24 | 36
abnormal bone mineralization 23 | 38
abnormal cranium morphology 23 | 36
enlarged spleen 23 | 41
limb grasping 23 | 41
persistence of hyaloid vascula... 22 | 33
decreased circulating aspartat... 21 | 34

Disease

Carcinoma 5,981 | 11,493
ovarian cancer 5,232 | 8,520
osteosarcoma 4,355 | 7,950
medulloblastoma, large-cell 3,424 | 6,241
psoriasis 3,361 | 6,694
glioblastoma 3,286 | 5,792
atypical teratoid / rhabdoid tumor 2,855 | 5,112
lung cancer 2,821 | 4,740
ependymoma 2,547 | 4,679
group 3 medulloblastoma 2,264 | 4,104
Breast cancer 2,068 | 3,578
adult high grade glioma 1,975 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 1,873 | 3,291
malignant mesothelioma 1,855 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 1,685 | 2,989
primitive neuroectodermal tumor 1,673 | 3,035
Kidney cancer 1,637 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 1,632 | 2,955
invasive ductal carcinoma 1,628 | 2,951
Astrocytoma, Pilocytic 1,618 | 3,081
oligodendroglioma 1,596 | 2,850
non-small cell lung cancer 1,553 | 2,890
astrocytic glioma 1,468 | 2,597
lung adenocarcinoma 1,445 | 2,716
lung carcinoma 1,373 | 2,843
Cancer 1,344 | 2,499
pancreatic cancer 1,339 | 2,398
subependymal giant cell astrocytoma 1,286 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 1,270 | 1,962
Pick disease 1,181 | 1,894
group 4 medulloblastoma 1,073 | 1,855
Multiple myeloma 1,064 | 1,332
tuberculosis 1,033 | 2,010
interstitial cystitis 998 | 2,312
pituitary cancer 964 | 1,972
ductal carcinoma in situ 925 | 1,745
breast carcinoma 922 | 1,638
ulcerative colitis 911 | 1,819
diabetes mellitus 908 | 1,728
Autosomal recessive predisposition 898 | 1,442
cystic fibrosis 870 | 1,696
colon cancer 850 | 1,478
acute quadriplegic myopathy 834 | 1,158
juvenile dermatomyositis 797 | 1,187
adrenocortical carcinoma 766 | 1,428
astrocytoma 752 | 1,146
dermatomyositis 721 | 966
primary pancreatic ductal adenocarcinoma 685 | 1,109
pediatric high grade glioma 645 | 1,064
Intellectual disability 642 | 1,016
Rheumatoid arthritis 634 | 1,191
spina bifida 603 | 1,074
Waldenstrons macroglobulinemia 602 | 765
Schizophrenia 586 | 1,160
nasopharyngeal carcinoma 536 | 1,058
non primary Sjogren syndrome sicca 509 | 891
acute myeloid leukemia 497 | 783
Epilepsy 478 | 792
cutaneous lupus erythematosus 474 | 1,057
active Crohn's disease 459 | 922
Atopic dermatitis 450 | 952
gastric carcinoma 436 | 807
Liver Cirrhosis, Experimental 435 | 769
Cognitive delay 431 | 608
Global developmental delay 431 | 608
Mental and motor retardation 431 | 608
progressive supranuclear palsy 428 | 676
esophageal adenocarcinoma 424 | 737
Dull intelligence 419 | 645
Low intelligence 419 | 645
Mental Retardation 419 | 645
Mental deficiency 419 | 645
Poor school performance 419 | 645
Duchenne muscular dystrophy 415 | 601
Muscle hypotonia 411 | 571
medulloblastoma 395 | 720
primary Sjogren syndrome 394 | 735
Liver cancer 391 | 604
aldosterone-producing adenoma 385 | 665
Seizures 380 | 596
active ulcerative colitis 375 | 764
Alzheimer's disease 371 | 658
Melanoma 368 | 711
autosomal dominant Emery-Dreifuss muscular dystrophy 349 | 510
Short stature 345 | 531
Bipolar Disorder 327 | 666
pancreatic carcinoma 321 | 562
Obesity 317 | 678
Down syndrome 314 | 499
hepatocellular carcinoma 305 | 547
Amyotrophic lateral sclerosis 304 | 451
Prostatic Neoplasms 291 | 495
Neurodegenerative disease 282 | 414
Endometriosis 267 | 540
sonic hedgehog group medulloblastoma 267 | 467
Breast Neoplasms 264 | 445
fibroadenoma 264 | 559
Skin cancer 259 | 469
Small head 255 | 374
gastric cancer 255 | 459

Tissue

Endocrine System 9,110 | 18,159
Female tissues 8,993 | 17,400
Digestive Tract 8,964 | 17,369
Skin and soft tissues 8,959 | 17,230
Male tissues 8,918 | 17,142
Blood and immune system 8,875 | 16,909
Liver and Pancreas 8,839 | 16,750
Nervous System 8,831 | 16,725
Urinary Tract 8,820 | 16,678
Respiratory system 8,782 | 16,393
Cardiovascular System 8,487 | 15,192

Target Family

Non-IDG 5,395 | 12,091
Enzyme 2,355 | 4,145
Transcription Factor 559 | 1,400
Kinase 428 | 634
Transporter 157 | 473
Epigenetic 153 | 242
Ion Channel 85 | 344
GPCR 44 | 408
TF/Epigenetic 23 | 38
oGPCR 15 | 421
Nuclear Receptor 14 | 48

HPM Tissue

Fetal Heart 9,228 | 9,228
Adult Testis 10,836 | 10,836
Adult Ovary 10,192 | 10,192
Adult Retina 10,115 | 10,115
CD8 Cells 9,840 | 9,840
Adult Pancreas 9,168 | 9,168
Fetal Ovary 9,118 | 9,118
Adult Liver 9,113 | 9,113
B Cells 9,086 | 9,086
Adult Frontal Cortex 9,048 | 9,048
Adult Prostate 8,952 | 8,952
Fetal Gut 8,640 | 8,640
Adult Adrenal 8,475 | 8,475
NK Cells 8,475 | 8,475
Fetal Liver 8,402 | 8,402
Adult Rectum 8,022 | 8,022
Fetal Testis 7,955 | 7,955
Adult Colon 7,915 | 7,915
Fetal Brain 7,866 | 7,866
CD4 Cells 7,773 | 7,773
Adult Gallbladder 7,612 | 7,612
Adult Spinal Cord 7,594 | 7,594
Adult Urinary Bladder 7,592 | 7,592
Monocytes 7,422 | 7,422
Adult Kidney 6,723 | 6,723
Adult Lung 6,663 | 6,663
Adult Heart 6,506 | 6,506
Platelets 6,131 | 6,131
Placenta 6,083 | 6,083
Adult Esophagus 4,936 | 4,936

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 215 ZNF215 Tdark Transcription Factor -0.51747 3.15 91
F-box/WD repeat-containing protein 2 FBXW2 Tbio Non-IDG -2.09381 115.1 104
COP9 signalosome complex subunit 9 COPS9 Tbio Non-IDG 0.21 0.92 14
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Calcium uptake protein 3, mitochondrial MICU3 Tdark Non-IDG -0.21085 1.14 50
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Serine/arginine-rich splicing factor 12 SRSF12 Tbio Non-IDG -0.09691 1.17 22