Development Level

Tbio 5,575 | 10,625
Tdark 1,766 | 7,003
Tchem 1,041 | 1,890
Tclin 266 | 602

Collection

Eligible Kinase Proteins 70 | 134
Eligible Ion Channel Proteins 33 | 117
Eligible non-olfactory GPCR Proteins 14 | 143

IMPC Term

preweaning lethality, complete... 395 | 633
preweaning lethality, incomple... 133 | 260
abnormal behavior 121 | 226
embryonic lethality prior to t... 119 | 187
decreased total body fat amoun... 109 | 186
decreased lean body mass 106 | 195
embryonic lethality prior to o... 101 | 148
decreased body weight 98 | 174
decreased bone mineral content 81 | 157
increased circulating alkaline... 65 | 119
abnormal bone structure 64 | 131
abnormal embryo size 64 | 112
decreased body length 62 | 108
decreased bone mineral density 62 | 126
increased or absent threshold ... 62 | 128
decreased circulating glucose ... 61 | 121
decreased grip strength 61 | 123
abnormal retina morphology 57 | 100
hyperactivity 57 | 108
increased lean body mass 54 | 107
increased mean corpuscular hem... 52 | 93
abnormal lens morphology 50 | 73
increased bone mineral content 49 | 92
increased grip strength 48 | 83
decreased circulating triglyce... 46 | 83
enlarged heart 46 | 111
short tibia 44 | 82
hypoactivity 43 | 89
decreased circulating HDL chol... 42 | 77
decreased circulating serum al... 42 | 79
increased mean corpuscular vol... 42 | 91
decreased circulating choleste... 41 | 85
decreased circulating insulin ... 40 | 75
increased fasted circulating g... 39 | 68
prenatal lethality prior to he... 39 | 64
decreased mean corpuscular vol... 38 | 50
abnormal retinal pigmentation 33 | 61
increased bone mineral density 32 | 52
decreased rib number 31 | 59
male infertility 31 | 62
decreased lumbar vertebrae num... 30 | 62
increased circulating HDL chol... 30 | 63
abnormal sleep behavior 29 | 63
decreased hemoglobin content 29 | 53
impaired glucose tolerance 29 | 52
increased circulating choleste... 29 | 53
decreased caudal vertebrae num... 28 | 49
decreased leukocyte cell numbe... 28 | 54
increased blood urea nitrogen ... 28 | 44
abnormal bone mineralization 26 | 55
abnormal coat/hair pigmentatio... 26 | 54
increased circulating sodium l... 26 | 71
decreased erythrocyte cell num... 25 | 43
decreased prepulse inhibition 25 | 52
increased exploration in new e... 25 | 56
increased heart weight 25 | 37
decreased circulating alanine ... 24 | 53
decreased startle reflex 24 | 48
improved glucose tolerance 24 | 56
increased circulating chloride... 24 | 43
thrombocytopenia 24 | 46
abnormal neural tube closure 23 | 37
cardiovascular system phenotyp... 23 | 35
decreased circulating alkaline... 23 | 41
decreased fasted circulating g... 23 | 49
decreased heart weight 23 | 44
increased total body fat amoun... 23 | 57
abnormal heart morphology 22 | 51
decreased circulating total pr... 22 | 41
increased body weight 22 | 42
increased hemoglobin content 22 | 45
abnormal gait 21 | 51
decreased circulating fructosa... 21 | 31
decreased eosinophil cell numb... 21 | 41
decreased mean corpuscular hem... 21 | 34
abnormal behavioral response t... 20 | 52
abnormal seminal vesicle morph... 20 | 47
decreased circulating LDL chol... 20 | 37
increased rib number 20 | 41
increased sacral vertebrae num... 20 | 62
increased startle reflex 20 | 38
abnormal eye morphology 19 | 38
decreased circulating free fat... 19 | 39
decreased neutrophil cell numb... 19 | 37
increased hematocrit 19 | 36
increased leukocyte cell numbe... 19 | 37
decreased T cell number 18 | 31
small testis 18 | 37
decreased blood urea nitrogen ... 17 | 31
decreased circulating calcium ... 17 | 33
decreased threshold for audito... 17 | 32
female infertility 17 | 34
increased circulating phosphat... 17 | 24
increased mean corpuscular hem... 17 | 25
abnormal spleen morphology 16 | 36
decreased circulating chloride... 16 | 32
persistence of hyaloid vascula... 16 | 22
decreased circulating aspartat... 15 | 27
increased circulating calcium ... 15 | 32
increased erythrocyte cell num... 15 | 26

Disease

ovarian cancer 4,878 | 8,484
osteosarcoma 4,037 | 7,933
psoriasis 3,225 | 6,685
medulloblastoma, large-cell 3,151 | 6,234
glioblastoma 2,956 | 5,572
lung cancer 2,548 | 4,466
atypical teratoid / rhabdoid tumor 2,257 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 1,844 | 3,289
malignant mesothelioma 1,671 | 3,162
Breast cancer 1,665 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 1,664 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 1,614 | 2,956
invasive ductal carcinoma 1,555 | 2,950
primitive neuroectodermal tumor 1,528 | 3,031
pilocytic astrocytoma 1,526 | 3,086
oligodendroglioma 1,490 | 2,849
non-small cell lung cancer 1,422 | 2,798
pediatric high grade glioma 1,415 | 2,712
lung adenocarcinoma 1,376 | 2,713
ependymoma 1,338 | 2,514
lung carcinoma 1,330 | 2,844
pancreatic cancer 1,295 | 2,300
Cancer 1,256 | 2,346
subependymal giant cell astrocytoma 1,217 | 2,287
Carcinoma 1,187 | 2,147
pancreatic ductal adenocarcinoma liver metastasis 1,142 | 1,795
astrocytic glioma 1,139 | 2,241
group 3 medulloblastoma 1,134 | 2,254
ulcerative colitis 1,086 | 2,087
Pick disease 1,069 | 1,893
adult high grade glioma 1,037 | 2,148
Multiple myeloma 1,030 | 1,327
group 4 medulloblastoma 997 | 1,875
interstitial cystitis 995 | 2,299
pituitary cancer 928 | 1,972
astrocytoma 906 | 1,493
ductal carcinoma in situ 881 | 1,745
diabetes mellitus 862 | 1,663
colon cancer 857 | 1,475
breast carcinoma 848 | 1,614
cystic fibrosis 836 | 1,665
tuberculosis 808 | 1,557
sonic hedgehog group medulloblastoma 785 | 1,482
acute quadriplegic myopathy 781 | 1,157
primary pancreatic ductal adenocarcinoma 776 | 1,271
medulloblastoma 766 | 1,524
juvenile dermatomyositis 760 | 1,189
posterior fossa group A ependymoma 734 | 1,511
adrenocortical carcinoma 718 | 1,427
dermatomyositis 681 | 933
posterior fossa group B ependymoma 644 | 1,530
Rheumatoid Arthritis 629 | 1,160
Waldenstrons macroglobulinemia 590 | 765
spina bifida 545 | 1,064
atypical teratoid/rhabdoid tumor 533 | 1,095
nasopharyngeal carcinoma 497 | 1,056
active Crohn's disease 478 | 918
cutaneous lupus erythematosus 477 | 1,056
non primary Sjogren syndrome sicca 461 | 840
acute myeloid leukemia 460 | 780
gastric carcinoma 448 | 832
esophageal adenocarcinoma 445 | 737
Atopic dermatitis 437 | 944
primary Sjogren syndrome 416 | 789
Duchenne muscular dystrophy 408 | 602
progressive supranuclear palsy 384 | 674
tuberculosis and treatment for 6 months 381 | 686
aldosterone-producing adenoma 360 | 664
Alzheimer's disease 354 | 644
Intellectual disability 334 | 573
Down syndrome 327 | 548
autosomal dominant Emery-Dreifuss muscular dystrophy 324 | 499
pancreatic carcinoma 311 | 567
Obesity 295 | 616
Prostatic Neoplasms 281 | 471
IGA Glomerulonephritis 278 | 454
hepatocellular carcinoma 270 | 532
Amyotrophic Lateral Sclerosis 264 | 431
fibroadenoma 258 | 557
Endometriosis 249 | 535
Neurodegenerative disease 247 | 383
mucosa-associated lymphoid tissue lymphoma 240 | 480
active ulcerative colitis 239 | 477
Mammary Neoplasms 237 | 410
hereditary spastic paraplegia 229 | 313
Schizophrenia 225 | 501
gastric cancer 224 | 430
non-small cell lung carcinoma 206 | 413
Multiple Sclerosis 202 | 498
Kidney disease 196 | 396
inflammatory breast cancer 196 | 404
chronic rhinosinusitis 195 | 512
Polycystic Ovary Syndrome 194 | 332
Parkinson's disease 187 | 364
nephrosclerosis 180 | 329
Stomach Neoplasms 172 | 282
interstitial lung disease 169 | 291
sarcoidosis 169 | 358
glioblastoma multiforme 168 | 347
Epilepsy 167 | 346

Tissue

Digestive Tract 8,648 | 18,473
Nervous System 8,626 | 18,561
Female tissues 8,623 | 18,647
Liver and Pancreas 8,612 | 18,136
Male tissues 8,608 | 17,969
Endocrine System 8,606 | 18,512
Urinary Tract 8,605 | 18,444
Blood and immune system 8,595 | 17,995
Cardiovascular System 8,582 | 17,958
Respiratory system 8,514 | 17,484
Skin and soft tissues 8,487 | 18,115

Target Family

Non-IDG 4,986 | 11,971
Enzyme 2,243 | 4,146
Transcription Factor 529 | 1,400
Kinase 406 | 634
Transporter 186 | 473
Epigenetic 129 | 242
Ion Channel 92 | 341
GPCR 40 | 406
Nuclear Receptor 14 | 48
TF/Epigenetic 14 | 38
oGPCR 9 | 421

HPM Tissue

Fetal Gut 8,648 | 8,648
Adult Testis 10,843 | 10,843
Adult Ovary 10,201 | 10,201
Adult Retina 10,124 | 10,124
CD8 Cells 9,849 | 9,849
Fetal Heart 9,239 | 9,239
Adult Pancreas 9,175 | 9,175
Fetal Ovary 9,127 | 9,127
Adult Liver 9,122 | 9,122
B Cells 9,091 | 9,091
Adult Frontal Cortex 9,054 | 9,054
Adult Prostate 8,963 | 8,963
NK Cells 8,481 | 8,481
Adult Adrenal 8,479 | 8,479
Fetal Liver 8,410 | 8,410
Adult Rectum 8,032 | 8,032
Fetal Testis 7,961 | 7,961
Adult Colon 7,921 | 7,921
Fetal Brain 7,871 | 7,871
CD4 Cells 7,779 | 7,779
Adult Gallbladder 7,619 | 7,619
Adult Urinary Bladder 7,601 | 7,601
Adult Spinal Cord 7,599 | 7,599
Monocytes 7,427 | 7,427
Adult Kidney 6,728 | 6,728
Adult Lung 6,669 | 6,669
Adult Heart 6,510 | 6,510
Platelets 6,133 | 6,133
Placenta 6,087 | 6,087
Adult Esophagus 4,939 | 4,939

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Syntaxin-1B STX1B Tbio Non-IDG -1.74488 52.6 27
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.31593 2169.0 108
Zinc finger protein 485 ZNF485 Tdark Transcription Factor 0.00000 48
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
ATP synthase F(0) complex subunit C3, mitochondrial ATP5G3 Tdark Enzyme -1.10871 11.9 27
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
Lumican LUM Tbio Non-IDG -2.67820 509.4 209