Development Level

Tbio 5,575 | 10,625
Tdark 1,766 | 7,003
Tchem 1,040 | 1,890
Tclin 266 | 602

Collection

Kinase: IDG Consortium (Targets) 65 | 125
Ion Channel: IDG Consortium (Targets) 32 | 102
Kinase: IDG Consortium (Complete/Control) 21 | 37
GPCR: IDG Consortium (Targets) 16 | 128
GPCR: IDG Consortium (Complete/Control) 3 | 24

IMPC Phenotype

preweaning lethality, complete... 395 | 633
preweaning lethality, incomple... 133 | 260
abnormal behavior 121 | 226
embryonic lethality prior to t... 119 | 187
decreased total body fat amoun... 109 | 186
decreased lean body mass 106 | 195
embryonic lethality prior to o... 101 | 148
decreased body weight 98 | 174
decreased bone mineral content 81 | 157
increased circulating alkaline... 65 | 119
abnormal bone structure 64 | 131
abnormal embryo size 64 | 112
decreased body length 62 | 108
decreased bone mineral density 62 | 126
increased or absent threshold ... 62 | 128
decreased circulating glucose ... 61 | 121
decreased grip strength 61 | 123
abnormal retina morphology 57 | 100
hyperactivity 57 | 108
increased lean body mass 54 | 107
increased mean corpuscular hem... 52 | 93
abnormal lens morphology 50 | 73
increased bone mineral content 49 | 92
increased grip strength 48 | 83
decreased circulating triglyce... 46 | 83
enlarged heart 46 | 111
short tibia 44 | 82
hypoactivity 43 | 89
decreased circulating HDL chol... 42 | 77
decreased circulating serum al... 42 | 79
increased mean corpuscular vol... 42 | 91
decreased circulating choleste... 41 | 85
decreased circulating insulin ... 40 | 75
increased fasted circulating g... 39 | 68
prenatal lethality prior to he... 39 | 64
decreased mean corpuscular vol... 38 | 50
abnormal retinal pigmentation 33 | 61
increased bone mineral density 32 | 52
decreased rib number 31 | 59
male infertility 31 | 62
decreased lumbar vertebrae num... 30 | 62
increased circulating HDL chol... 30 | 63
abnormal sleep behavior 29 | 63
decreased hemoglobin content 29 | 53
impaired glucose tolerance 29 | 52
increased circulating choleste... 29 | 53
decreased caudal vertebrae num... 28 | 49
decreased leukocyte cell numbe... 28 | 54
increased blood urea nitrogen ... 28 | 44
abnormal bone mineralization 26 | 55
abnormal coat-hair pigmentatio... 26 | 54
increased circulating sodium l... 26 | 71
decreased erythrocyte cell num... 25 | 43
decreased prepulse inhibition 25 | 52
increased exploration in new e... 25 | 56
increased heart weight 25 | 37
decreased circulating alanine ... 24 | 53
decreased startle reflex 24 | 48
improved glucose tolerance 24 | 56
increased circulating chloride... 24 | 43
thrombocytopenia 24 | 46
abnormal neural tube closure 23 | 37
cardiovascular system phenotyp... 23 | 35
decreased circulating alkaline... 23 | 41
decreased fasted circulating g... 23 | 49
decreased heart weight 23 | 44
increased total body fat amoun... 23 | 57
abnormal heart morphology 22 | 51
decreased circulating total pr... 22 | 41
increased body weight 22 | 42
increased hemoglobin content 22 | 45
abnormal gait 21 | 51
decreased circulating fructosa... 21 | 31
decreased eosinophil cell numb... 21 | 41
decreased mean corpuscular hem... 21 | 34
abnormal behavioral response t... 20 | 52
abnormal seminal vesicle morph... 20 | 47
decreased circulating LDL chol... 20 | 37
increased rib number 20 | 41
increased sacral vertebrae num... 20 | 62
increased startle reflex 20 | 38
abnormal eye morphology 19 | 38
decreased circulating free fat... 19 | 39
decreased neutrophil cell numb... 19 | 37
increased hematocrit 19 | 36
increased leukocyte cell numbe... 19 | 37
decreased T cell number 18 | 31
small testis 18 | 37
decreased blood urea nitrogen ... 17 | 31
decreased circulating calcium ... 17 | 33
decreased threshold for audito... 17 | 32
female infertility 17 | 34
increased circulating phosphat... 17 | 24
increased mean corpuscular hem... 17 | 25
abnormal spleen morphology 16 | 36
decreased circulating chloride... 16 | 32
persistence of hyaloid vascula... 16 | 22
decreased circulating aspartat... 15 | 27
increased circulating calcium ... 15 | 32
increased erythrocyte cell num... 15 | 26

Disease

ovarian cancer 4,881 | 8,491
osteosarcoma 4,037 | 7,933
psoriasis 3,225 | 6,685
medulloblastoma, large-cell 3,151 | 6,234
glioblastoma 2,956 | 5,572
lung cancer 2,550 | 4,473
atypical teratoid / rhabdoid tumor 2,257 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 1,844 | 3,289
malignant mesothelioma 1,672 | 3,163
Breast cancer 1,667 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 1,664 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 1,614 | 2,956
invasive ductal carcinoma 1,555 | 2,950
primitive neuroectodermal tumor 1,528 | 3,031
pilocytic astrocytoma 1,526 | 3,086
oligodendroglioma 1,490 | 2,849
non-small cell lung cancer 1,422 | 2,798
pediatric high grade glioma 1,415 | 2,712
lung adenocarcinoma 1,376 | 2,714
ependymoma 1,338 | 2,514
lung carcinoma 1,330 | 2,844
pancreatic cancer 1,295 | 2,300
Cancer 1,256 | 2,346
subependymal giant cell astrocytoma 1,217 | 2,287
Carcinoma 1,187 | 2,147
pancreatic ductal adenocarcinoma liver metastasis 1,142 | 1,795
astrocytic glioma 1,139 | 2,241
group 3 medulloblastoma 1,134 | 2,254
ulcerative colitis 1,086 | 2,087
Pick disease 1,069 | 1,893
adult high grade glioma 1,037 | 2,148
Multiple myeloma 1,029 | 1,327
group 4 medulloblastoma 997 | 1,875
interstitial cystitis 995 | 2,299
pituitary cancer 928 | 1,972
astrocytoma 906 | 1,493
ductal carcinoma in situ 881 | 1,745
diabetes mellitus 862 | 1,663
colon cancer 857 | 1,475
breast carcinoma 848 | 1,614
cystic fibrosis 837 | 1,670
tuberculosis 811 | 1,563
sonic hedgehog group medulloblastoma 785 | 1,482
acute quadriplegic myopathy 781 | 1,157
primary pancreatic ductal adenocarcinoma 776 | 1,271
medulloblastoma 766 | 1,524
juvenile dermatomyositis 760 | 1,189
posterior fossa group A ependymoma 734 | 1,511
adrenocortical carcinoma 718 | 1,427
dermatomyositis 681 | 966
posterior fossa group B ependymoma 644 | 1,530
Rheumatoid Arthritis 629 | 1,170
Waldenstrons macroglobulinemia 589 | 764
spina bifida 545 | 1,064
atypical teratoid/rhabdoid tumor 533 | 1,095
nasopharyngeal carcinoma 497 | 1,056
active Crohn's disease 478 | 918
cutaneous lupus erythematosus 477 | 1,056
acute myeloid leukemia 462 | 785
non primary Sjogren syndrome sicca 461 | 840
gastric carcinoma 448 | 832
esophageal adenocarcinoma 445 | 737
Atopic dermatitis 437 | 944
primary Sjogren syndrome 415 | 788
Duchenne muscular dystrophy 408 | 602
progressive supranuclear palsy 384 | 674
tuberculosis and treatment for 6 months 381 | 686
aldosterone-producing adenoma 360 | 664
Alzheimer's disease 354 | 644
Intellectual disability 334 | 573
Down syndrome 327 | 548
autosomal dominant Emery-Dreifuss muscular dystrophy 324 | 499
pancreatic carcinoma 311 | 567
Obesity 295 | 616
hepatocellular carcinoma 283 | 550
Prostatic Neoplasms 281 | 471
IGA Glomerulonephritis 278 | 454
Amyotrophic Lateral Sclerosis 264 | 432
fibroadenoma 258 | 557
Endometriosis 249 | 535
Neurodegenerative disease 247 | 383
mucosa-associated lymphoid tissue lymphoma 240 | 480
active ulcerative colitis 239 | 477
Mammary Neoplasms 237 | 410
hereditary spastic paraplegia 229 | 313
Schizophrenia 227 | 503
gastric cancer 226 | 436
non-small cell lung carcinoma 206 | 413
Multiple Sclerosis 202 | 498
Kidney disease 196 | 397
inflammatory breast cancer 196 | 404
Polycystic Ovary Syndrome 195 | 334
chronic rhinosinusitis 195 | 512
Parkinson's disease 187 | 364
nephrosclerosis 180 | 329
Stomach Neoplasms 172 | 282
interstitial lung disease 170 | 292
sarcoidosis 170 | 368
glioblastoma multiforme 168 | 347
Epilepsy 167 | 346

Tissue

Digestive Tract 8,647 | 18,472
Nervous System 8,625 | 18,560
Female tissues 8,622 | 18,646
Liver and Pancreas 8,611 | 18,135
Male tissues 8,607 | 17,968
Endocrine System 8,605 | 18,511
Urinary Tract 8,604 | 18,443
Blood and immune system 8,594 | 17,994
Cardiovascular System 8,581 | 17,957
Respiratory system 8,513 | 17,483
Skin and soft tissues 8,486 | 18,114

Target Family

Non-IDG 4,986 | 11,969
Enzyme 2,242 | 4,146
Transcription Factor 529 | 1,400
Kinase 406 | 634
Transporter 186 | 473
Epigenetic 129 | 242
Ion Channel 92 | 341
GPCR 40 | 408
Nuclear Receptor 14 | 48
TF/Epigenetic 14 | 38
oGPCR 9 | 421

HPM Tissue

Fetal Gut 8,647 | 8,647
Adult Testis 10,842 | 10,842
Adult Ovary 10,200 | 10,200
Adult Retina 10,123 | 10,123
CD8 Cells 9,848 | 9,848
Fetal Heart 9,238 | 9,238
Adult Pancreas 9,174 | 9,174
Fetal Ovary 9,126 | 9,126
Adult Liver 9,121 | 9,121
B Cells 9,090 | 9,090
Adult Frontal Cortex 9,053 | 9,053
Adult Prostate 8,962 | 8,962
NK Cells 8,480 | 8,480
Adult Adrenal 8,478 | 8,478
Fetal Liver 8,409 | 8,409
Adult Rectum 8,031 | 8,031
Fetal Testis 7,960 | 7,960
Adult Colon 7,920 | 7,920
Fetal Brain 7,870 | 7,870
CD4 Cells 7,778 | 7,778
Adult Gallbladder 7,618 | 7,618
Adult Urinary Bladder 7,600 | 7,600
Adult Spinal Cord 7,598 | 7,598
Monocytes 7,426 | 7,426
Adult Kidney 6,727 | 6,727
Adult Lung 6,668 | 6,668
Adult Heart 6,509 | 6,509
Platelets 6,132 | 6,132
Placenta 6,086 | 6,086
Adult Esophagus 4,938 | 4,938

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.50722 29.2 46
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
Zinc finger protein 215 ZNF215 Tdark Transcription Factor -0.47111 3.15 74
Epithelial membrane protein 3 EMP3 Tbio Non-IDG -1.64647 44.8 131
UDP-glucuronosyltransferase 2B15 UGT2B15 Tchem Enzyme -1.77071 60.2 66
Hydroxymethylglutaryl-CoA synthase, mitochondrial HMGCS2 Tbio Enzyme -1.69372 46.6 95
Phosphoglycerate mutase 2 PGAM2 Tbio Enzyme -1.54638 36.2 160
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.13194 126.3 290
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.04868 9.00 130
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521