Development Level
Tbio | 5,498 | 11,445 | |
Tdark | 1,337 | 6,588 | |
Tchem | 750 | 1,598 | |
Tclin | 281 | 613 |
Collection
RFA-RM-18-021 | 100 | 328 | |
Kinase: IDG Consortium (Target... | 58 | 125 | |
Ion Channel: IDG Consortium (T... | 35 | 99 | |
Kinase: IDG Consortium (Comple... | 20 | 37 | |
GPCR: IDG Consortium (Targets) | 9 | 126 | |
GPCR: IDG Consortium (Complete... | 3 | 25 |
IMPC Phenotype
preweaning lethality, complete... | 634 | 979 | |
preweaning lethality, incomple... | 260 | 499 | |
embryonic lethality prior to t... | 170 | 278 | |
abnormal behavior | 160 | 298 | |
embryonic lethality prior to o... | 159 | 239 | |
abnormal embryo size | 131 | 220 | |
decreased total body fat amoun... | 110 | 207 | |
abnormal bone structure | 102 | 187 | |
decreased body weight | 90 | 161 | |
increased lean body mass | 88 | 172 | |
decreased bone mineral content | 84 | 151 | |
decreased vertical activity | 84 | 208 | |
hyperactivity | 84 | 148 | |
enlarged heart | 73 | 210 | |
increased circulating alkaline... | 71 | 122 | |
hypoactivity | 70 | 132 | |
increased total body fat amoun... | 70 | 134 | |
decreased bone mineral density | 68 | 126 | |
embryonic growth retardation | 65 | 106 | |
decreased circulating glucose ... | 62 | 126 | |
decreased grip strength | 62 | 116 | |
decreased lean body mass | 62 | 135 | |
increased startle reflex | 60 | 112 | |
abnormal heart morphology | 58 | 162 | |
increased bone mineral content | 57 | 108 | |
decreased body length | 53 | 101 | |
decreased circulating choleste... | 53 | 93 | |
prenatal lethality prior to he... | 52 | 87 | |
increased or absent threshold ... | 51 | 101 | |
short tibia | 51 | 97 | |
abnormal seminal vesicle morph... | 50 | 114 | |
increased mean corpuscular hem... | 47 | 96 | |
decreased prepulse inhibition | 45 | 82 | |
male infertility | 45 | 123 | |
abnormal lens morphology | 43 | 81 | |
cataract | 43 | 92 | |
decreased circulating HDL chol... | 43 | 68 | |
decreased mean corpuscular vol... | 42 | 79 | |
increased mean corpuscular vol... | 42 | 92 | |
decreased startle reflex | 41 | 75 | |
decreased circulating serum al... | 40 | 82 | |
abnormal retina morphology | 39 | 71 | |
decreased circulating triglyce... | 38 | 79 | |
abnormal gait | 37 | 69 | |
decreased circulating insulin ... | 37 | 76 | |
increased bone mineral density | 37 | 72 | |
increased fasted circulating g... | 37 | 76 | |
increased heart weight | 37 | 62 | |
abnormal behavioral response t... | 36 | 66 | |
improved glucose tolerance | 35 | 79 | |
abnormal eye morphology | 34 | 68 | |
edema | 34 | 59 | |
impaired glucose tolerance | 34 | 75 | |
increased circulating choleste... | 34 | 66 | |
decreased circulating alkaline... | 33 | 46 | |
decreased fasted circulating g... | 32 | 65 | |
decreased leukocyte cell numbe... | 32 | 73 | |
decreased lymphocyte cell numb... | 32 | 83 | |
increased circulating sodium l... | 32 | 71 | |
abnormal kidney morphology | 30 | 65 | |
increased circulating HDL chol... | 30 | 80 | |
small testis | 29 | 58 | |
decreased hemoglobin content | 28 | 68 | |
decreased neutrophil cell numb... | 28 | 42 | |
increased blood urea nitrogen ... | 28 | 48 | |
abnormal coat-hair pigmentatio... | 27 | 64 | |
decreased caudal vertebrae num... | 27 | 53 | |
decreased circulating total pr... | 27 | 49 | |
decreased erythrocyte cell num... | 27 | 62 | |
abnormal sleep behavior | 26 | 70 | |
increased mean platelet volume | 26 | 45 | |
small superior vagus ganglion | 26 | 74 | |
thrombocytopenia | 26 | 56 | |
decreased mean corpuscular hem... | 25 | 50 | |
increased monocyte cell number | 25 | 63 | |
decreased circulating alanine ... | 24 | 47 | |
increased circulating chloride... | 23 | 41 | |
increased erythrocyte cell num... | 23 | 39 | |
increased leukocyte cell numbe... | 23 | 47 | |
increased red blood cell distr... | 23 | 34 | |
pallor | 23 | 34 | |
abnormal neural tube closure | 22 | 46 | |
abnormal skin morphology | 22 | 50 | |
abnormal spleen morphology | 22 | 55 | |
decreased circulating LDL chol... | 22 | 38 | |
decreased red blood cell distr... | 22 | 41 | |
increased hematocrit | 22 | 46 | |
abnormal testis morphology | 21 | 43 | |
increased circulating triglyce... | 21 | 42 | |
increased grip strength | 21 | 41 | |
increased neutrophil cell numb... | 21 | 46 | |
limb grasping | 21 | 41 | |
tremors | 21 | 39 | |
abnormal cranium morphology | 20 | 36 | |
female infertility | 20 | 60 | |
increased hemoglobin content | 20 | 45 | |
persistence of hyaloid vascula... | 20 | 33 | |
decreased circulating aspartat... | 19 | 34 | |
decreased circulating fructosa... | 19 | 30 | |
decreased hematocrit | 19 | 46 |
Disease
Tissue
Endocrine System | 7,772 | 18,159 | |
Female tissues | 7,664 | 17,400 | |
Digestive Tract | 7,662 | 17,369 | |
Skin and soft tissues | 7,649 | 17,230 | |
Male tissues | 7,599 | 17,142 | |
Nervous System | 7,577 | 16,725 | |
Blood and immune system | 7,559 | 16,909 | |
Liver and Pancreas | 7,540 | 16,750 | |
Urinary Tract | 7,517 | 16,678 | |
Respiratory system | 7,474 | 16,393 | |
Cardiovascular System | 7,218 | 15,192 |
Target Family
Non-IDG | 4,691 | 12,091 | |
Enzyme | 2,045 | 4,145 | |
Kinase | 381 | 634 | |
Transcription Factor | 278 | 1,400 | |
Transporter | 155 | 473 | |
Epigenetic | 129 | 242 | |
Ion Channel | 116 | 344 | |
GPCR | 46 | 408 | |
TF/Epigenetic | 11 | 38 | |
Nuclear Receptor | 10 | 48 | |
oGPCR | 4 | 421 |
HPM Tissue
Fetal Brain | 7,866 | 7,866 | |
Adult Testis | 10,836 | 10,836 | |
Adult Ovary | 10,192 | 10,192 | |
Adult Retina | 10,115 | 10,115 | |
CD8 Cells | 9,840 | 9,840 | |
Fetal Heart | 9,228 | 9,228 | |
Adult Pancreas | 9,168 | 9,168 | |
Fetal Ovary | 9,118 | 9,118 | |
Adult Liver | 9,113 | 9,113 | |
B Cells | 9,086 | 9,086 | |
Adult Frontal Cortex | 9,048 | 9,048 | |
Adult Prostate | 8,952 | 8,952 | |
Fetal Gut | 8,640 | 8,640 | |
Adult Adrenal | 8,475 | 8,475 | |
NK Cells | 8,475 | 8,475 | |
Fetal Liver | 8,402 | 8,402 | |
Adult Rectum | 8,022 | 8,022 | |
Fetal Testis | 7,955 | 7,955 | |
Adult Colon | 7,915 | 7,915 | |
CD4 Cells | 7,773 | 7,773 | |
Adult Gallbladder | 7,612 | 7,612 | |
Adult Spinal Cord | 7,594 | 7,594 | |
Adult Urinary Bladder | 7,592 | 7,592 | |
Monocytes | 7,422 | 7,422 | |
Adult Kidney | 6,723 | 6,723 | |
Adult Lung | 6,663 | 6,663 | |
Adult Heart | 6,506 | 6,506 | |
Platelets | 6,131 | 6,131 | |
Placenta | 6,083 | 6,083 | |
Adult Esophagus | 4,936 | 4,936 |
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