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Development Level

Tbio 5,162 | 10,625
Tdark 1,528 | 7,003
Tchem 904 | 1,890
Tclin 276 | 602

Collection

Kinase: IDG Consortium (Targets) 58 | 125
Ion Channel: IDG Consortium (Targets) 34 | 102
Kinase: IDG Consortium (Complete/Control) 20 | 37
GPCR: IDG Consortium (Targets) 9 | 127
GPCR: IDG Consortium (Complete/Control) 3 | 26

IMPC Phenotype

preweaning lethality, complete... 389 | 633
preweaning lethality, incomple... 134 | 260
abnormal behavior 125 | 226
embryonic lethality prior to t... 113 | 187
decreased lean body mass 106 | 195
decreased body weight 103 | 174
decreased total body fat amoun... 102 | 186
embryonic lethality prior to o... 98 | 148
decreased bone mineral content 90 | 157
increased circulating alkaline... 74 | 119
abnormal bone structure 73 | 131
increased or absent threshold ... 71 | 128
decreased bone mineral density 69 | 126
decreased body length 66 | 108
decreased grip strength 65 | 123
abnormal embryo size 63 | 112
hyperactivity 62 | 108
decreased circulating glucose ... 59 | 121
increased lean body mass 55 | 107
decreased circulating choleste... 54 | 85
abnormal retina morphology 52 | 100
decreased circulating HDL chol... 52 | 77
increased mean corpuscular hem... 52 | 93
hypoactivity 44 | 89
increased bone mineral content 43 | 92
short tibia 42 | 82
prenatal lethality prior to he... 41 | 64
increased grip strength 40 | 83
abnormal lens morphology 39 | 73
decreased circulating insulin ... 39 | 75
decreased circulating triglyce... 39 | 83
enlarged heart 38 | 111
decreased circulating serum al... 37 | 79
increased fasted circulating g... 37 | 68
increased mean corpuscular vol... 36 | 91
decreased lumbar vertebrae num... 33 | 62
decreased mean corpuscular vol... 33 | 50
decreased rib number 33 | 59
abnormal retinal pigmentation 32 | 61
increased circulating sodium l... 32 | 71
decreased leukocyte cell numbe... 30 | 54
male infertility 30 | 62
abnormal gait 29 | 51
increased exploration in new e... 29 | 56
impaired glucose tolerance 28 | 52
decreased fasted circulating g... 27 | 49
increased blood urea nitrogen ... 27 | 44
increased sacral vertebrae num... 27 | 62
abnormal bone mineralization 26 | 55
abnormal sleep behavior 26 | 63
decreased circulating alanine ... 26 | 53
decreased prepulse inhibition 26 | 52
improved glucose tolerance 26 | 56
increased circulating HDL chol... 26 | 63
decreased circulating alkaline... 25 | 41
decreased startle reflex 25 | 48
increased circulating chloride... 25 | 43
increased circulating choleste... 25 | 53
abnormal behavioral response t... 24 | 52
abnormal coat-hair pigmentatio... 24 | 54
increased bone mineral density 24 | 52
increased total body fat amoun... 24 | 57
decreased caudal vertebrae num... 23 | 49
decreased eosinophil cell numb... 23 | 41
decreased hemoglobin content 23 | 53
decreased circulating LDL chol... 22 | 37
decreased heart weight 22 | 44
increased heart weight 22 | 37
increased hemoglobin content 22 | 45
decreased circulating fructosa... 21 | 31
decreased circulating total pr... 21 | 41
decreased mean corpuscular hem... 21 | 34
abnormal cranium morphology 20 | 32
abnormal neural tube closure 20 | 37
decreased circulating free fat... 20 | 39
increased startle reflex 20 | 38
abnormal seminal vesicle morph... 19 | 47
decreased circulating calcium ... 19 | 33
thrombocytopenia 19 | 46
decreased erythrocyte cell num... 18 | 43
increased body weight 18 | 42
increased rib number 18 | 41
limb grasping 18 | 35
small testis 18 | 37
decreased neutrophil cell numb... 17 | 37
increased circulating calcium ... 17 | 32
increased erythrocyte cell num... 17 | 26
abnormal eye morphology 16 | 38
abnormal heart morphology 16 | 51
abnormal testis morphology 16 | 30
decreased circulating aspartat... 16 | 27
increased hematocrit 16 | 36
increased leukocyte cell numbe... 16 | 37
abnormal locomotor activation 15 | 26
abnormal rib morphology 15 | 28
decreased circulating iron lev... 15 | 25
embryonic growth retardation 15 | 28
female infertility 15 | 34
increased circulating phosphat... 15 | 24
tremors 15 | 34

Disease

ovarian cancer 4,514 | 8,491
osteosarcoma 3,701 | 7,933
medulloblastoma, large-cell 3,184 | 6,234
glioblastoma 2,916 | 5,572
psoriasis 2,896 | 6,685
atypical teratoid / rhabdoid tumor 2,368 | 4,369
lung cancer 2,265 | 4,473
oligodendroglioma 1,615 | 2,849
intraductal papillary-mucinous neoplasm (IPMN) 1,573 | 3,289
primitive neuroectodermal tumor 1,565 | 3,031
malignant mesothelioma 1,534 | 3,163
Breast cancer 1,522 | 3,098
pilocytic astrocytoma 1,505 | 3,086
ependymoma 1,430 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 1,412 | 2,988
pediatric high grade glioma 1,411 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 1,381 | 2,956
invasive ductal carcinoma 1,353 | 2,950
non-small cell lung cancer 1,242 | 2,798
astrocytic glioma 1,229 | 2,241
subependymal giant cell astrocytoma 1,214 | 2,287
lung adenocarcinoma 1,205 | 2,714
lung carcinoma 1,193 | 2,844
Carcinoma 1,181 | 2,147
Pick disease 1,156 | 1,893
group 3 medulloblastoma 1,068 | 2,254
Cancer 1,060 | 2,346
pancreatic cancer 1,051 | 2,300
adult high grade glioma 1,044 | 2,148
pancreatic ductal adenocarcinoma liver metastasis 995 | 1,795
Multiple myeloma 967 | 1,327
group 4 medulloblastoma 934 | 1,875
astrocytoma 919 | 1,493
pituitary cancer 877 | 1,972
ulcerative colitis 875 | 2,087
medulloblastoma 844 | 1,524
interstitial cystitis 822 | 2,299
ductal carcinoma in situ 773 | 1,745
sonic hedgehog group medulloblastoma 757 | 1,482
diabetes mellitus 754 | 1,663
breast carcinoma 742 | 1,614
colon cancer 730 | 1,475
cystic fibrosis 730 | 1,670
acute quadriplegic myopathy 726 | 1,157
tuberculosis 712 | 1,563
posterior fossa group A ependymoma 671 | 1,511
primary pancreatic ductal adenocarcinoma 664 | 1,271
juvenile dermatomyositis 655 | 1,189
posterior fossa group B ependymoma 638 | 1,530
adrenocortical carcinoma 615 | 1,427
dermatomyositis 615 | 966
Rheumatoid Arthritis 570 | 1,170
Waldenstrons macroglobulinemia 553 | 764
atypical teratoid/rhabdoid tumor 510 | 1,095
spina bifida 488 | 1,064
nasopharyngeal carcinoma 437 | 1,056
non primary Sjogren syndrome sicca 428 | 840
acute myeloid leukemia 417 | 785
gastric carcinoma 407 | 832
Alzheimer's disease 377 | 644
progressive supranuclear palsy 373 | 674
active Crohn's disease 371 | 918
Intellectual disability 367 | 573
cutaneous lupus erythematosus 365 | 1,056
esophageal adenocarcinoma 357 | 737
tuberculosis and treatment for 6 months 350 | 686
aldosterone-producing adenoma 341 | 664
Duchenne muscular dystrophy 335 | 602
Atopic dermatitis 323 | 944
primary Sjogren syndrome 322 | 788
Down syndrome 296 | 548
autosomal dominant Emery-Dreifuss muscular dystrophy 280 | 499
Schizophrenia 268 | 503
pancreatic carcinoma 263 | 567
Amyotrophic Lateral Sclerosis 259 | 432
Neurodegenerative disease 251 | 383
Obesity 249 | 616
hepatocellular carcinoma 240 | 550
Prostatic Neoplasms 230 | 471
fibroadenoma 226 | 557
hereditary spastic paraplegia 225 | 313
IGA Glomerulonephritis 221 | 454
Epilepsy 216 | 346
Parkinson's disease 213 | 364
Mammary Neoplasms 202 | 410
Endometriosis 196 | 535
gastric cancer 189 | 436
active ulcerative colitis 188 | 477
chronic rhinosinusitis 188 | 512
mucosa-associated lymphoid tissue lymphoma 188 | 480
non-small cell lung carcinoma 185 | 413
Polycystic Ovary Syndrome 174 | 334
Autistic Disorder 170 | 320
inflammatory breast cancer 165 | 404
glioblastoma multiforme 154 | 347
Multiple Sclerosis 153 | 498
Kidney disease 150 | 397
Stomach Neoplasms 149 | 282
interstitial lung disease 148 | 292
sarcoidosis 147 | 368

Tissue

Nervous System 7,870 | 18,560
Female tissues 7,861 | 18,646
Blood and immune system 7,838 | 17,994
Digestive Tract 7,837 | 18,472
Endocrine System 7,831 | 18,511
Male tissues 7,831 | 17,968
Liver and Pancreas 7,827 | 18,135
Cardiovascular System 7,824 | 17,957
Urinary Tract 7,824 | 18,443
Respiratory system 7,763 | 17,483
Skin and soft tissues 7,732 | 18,114

Target Family

Non-IDG 4,694 | 11,969
Enzyme 2,046 | 4,146
Kinase 381 | 634
Transcription Factor 278 | 1,400
Transporter 156 | 473
Epigenetic 130 | 242
Ion Channel 114 | 341
GPCR 46 | 408
TF/Epigenetic 11 | 38
Nuclear Receptor 10 | 48
oGPCR 4 | 421

HPM Tissue

Fetal Brain 7,870 | 7,870
Adult Testis 10,842 | 10,842
Adult Ovary 10,200 | 10,200
Adult Retina 10,123 | 10,123
CD8 Cells 9,848 | 9,848
Fetal Heart 9,238 | 9,238
Adult Pancreas 9,174 | 9,174
Fetal Ovary 9,126 | 9,126
Adult Liver 9,121 | 9,121
B Cells 9,090 | 9,090
Adult Frontal Cortex 9,053 | 9,053
Adult Prostate 8,962 | 8,962
Fetal Gut 8,647 | 8,647
NK Cells 8,480 | 8,480
Adult Adrenal 8,478 | 8,478
Fetal Liver 8,409 | 8,409
Adult Rectum 8,031 | 8,031
Fetal Testis 7,960 | 7,960
Adult Colon 7,920 | 7,920
CD4 Cells 7,778 | 7,778
Adult Gallbladder 7,618 | 7,618
Adult Urinary Bladder 7,600 | 7,600
Adult Spinal Cord 7,598 | 7,598
Monocytes 7,426 | 7,426
Adult Kidney 6,727 | 6,727
Adult Lung 6,668 | 6,668
Adult Heart 6,509 | 6,509
Platelets 6,132 | 6,132
Placenta 6,086 | 6,086
Adult Esophagus 4,938 | 4,938

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.50722 29.2 46
Paralemmin-3 PALM3 Tbio Non-IDG -0.47712 3.44 66
Myeloma-overexpressed gene 2 protein COPS9 Tdark Non-IDG 0.21 0.67 12
Epithelial membrane protein 3 EMP3 Tbio Non-IDG -1.64647 44.8 131
Hydroxymethylglutaryl-CoA synthase, mitochondrial HMGCS2 Tbio Enzyme -1.69372 46.6 95
Phosphoglycerate mutase 2 PGAM2 Tbio Enzyme -1.54638 36.2 160
Neuron-specific protein family member 1 NSG1 Tbio Non-IDG -1.10592 14.0 156
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.04868 9.00 130
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
Splicing regulatory glutamine/lysine-rich protein 1 SREK1 Tdark Non-IDG -0.37946 3.77 39