Development Level

Tbio 4,994 | 10,625
Tdark 1,363 | 7,003
Tchem 987 | 1,890
Tclin 256 | 602

Collection

Kinase: IDG Consortium (Targets) 55 | 125
Ion Channel: IDG Consortium (Targets) 24 | 102
Kinase: IDG Consortium (Complete/Control) 21 | 37
GPCR: IDG Consortium (Targets) 14 | 127
GPCR: IDG Consortium (Complete/Control) 4 | 26

IMPC Phenotype

preweaning lethality, complete... 356 | 633
preweaning lethality, incomple... 131 | 260
decreased lean body mass 111 | 195
embryonic lethality prior to t... 107 | 187
abnormal behavior 106 | 226
decreased total body fat amoun... 103 | 186
decreased body weight 93 | 174
embryonic lethality prior to o... 91 | 148
decreased bone mineral content 83 | 157
increased circulating alkaline... 72 | 119
abnormal bone structure 69 | 131
decreased bone mineral density 66 | 126
abnormal embryo size 63 | 112
decreased circulating glucose ... 63 | 121
increased or absent threshold ... 63 | 128
decreased grip strength 61 | 123
decreased body length 60 | 108
hyperactivity 56 | 108
increased lean body mass 54 | 107
abnormal retina morphology 51 | 100
increased mean corpuscular hem... 50 | 93
increased bone mineral content 46 | 92
decreased circulating choleste... 44 | 85
decreased circulating HDL chol... 43 | 77
decreased circulating triglyce... 41 | 83
abnormal lens morphology 40 | 73
decreased circulating serum al... 40 | 79
short tibia 40 | 82
decreased circulating insulin ... 39 | 75
hypoactivity 39 | 89
decreased mean corpuscular vol... 38 | 50
enlarged heart 38 | 111
increased grip strength 38 | 83
increased fasted circulating g... 37 | 68
increased mean corpuscular vol... 37 | 91
prenatal lethality prior to he... 33 | 64
male infertility 32 | 62
increased circulating sodium l... 31 | 71
abnormal sleep behavior 30 | 63
decreased lumbar vertebrae num... 30 | 62
impaired glucose tolerance 29 | 52
abnormal bone mineralization 27 | 55
abnormal retinal pigmentation 27 | 61
increased hemoglobin content 27 | 45
thrombocytopenia 27 | 46
decreased fasted circulating g... 26 | 49
improved glucose tolerance 26 | 56
increased bone mineral density 26 | 52
increased circulating HDL chol... 26 | 63
increased circulating choleste... 26 | 53
increased exploration in new e... 26 | 56
abnormal behavioral response t... 25 | 52
abnormal coat-hair pigmentatio... 25 | 54
decreased leukocyte cell numbe... 25 | 54
decreased rib number 25 | 59
decreased caudal vertebrae num... 24 | 49
increased body weight 24 | 42
increased sacral vertebrae num... 24 | 62
decreased circulating alanine ... 23 | 53
decreased hemoglobin content 23 | 53
increased total body fat amoun... 23 | 57
decreased circulating total pr... 22 | 41
decreased mean corpuscular hem... 22 | 34
decreased startle reflex 22 | 48
increased blood urea nitrogen ... 22 | 44
abnormal gait 21 | 51
decreased eosinophil cell numb... 21 | 41
decreased heart weight 21 | 44
decreased prepulse inhibition 21 | 52
abnormal neural tube closure 20 | 37
abnormal seminal vesicle morph... 20 | 47
increased circulating chloride... 20 | 43
decreased circulating LDL chol... 19 | 37
decreased circulating alkaline... 19 | 41
increased heart weight 19 | 37
increased hematocrit 19 | 36
increased leukocyte cell numbe... 19 | 37
cardiovascular system phenotyp... 18 | 35
decreased circulating calcium ... 18 | 33
decreased circulating fructosa... 18 | 31
decreased neutrophil cell numb... 18 | 37
increased rib number 18 | 41
abnormal eye morphology 17 | 38
decreased circulating aspartat... 17 | 27
decreased circulating free fat... 17 | 39
small testis 17 | 37
abnormal cranium morphology 16 | 32
abnormal heart morphology 16 | 51
abnormal testis morphology 16 | 30
decreased blood urea nitrogen ... 16 | 31
decreased erythrocyte cell num... 16 | 43
limb grasping 16 | 35
decreased circulating creatini... 15 | 31
decreased circulating iron lev... 15 | 25
decreased threshold for audito... 15 | 32
embryonic growth retardation 15 | 28
increased circulating calcium ... 15 | 32
increased circulating phosphat... 15 | 24
increased circulating potassiu... 15 | 31
increased startle reflex 15 | 38

Disease

ovarian cancer 4,448 | 8,491
osteosarcoma 3,612 | 7,933
psoriasis 2,947 | 6,685
medulloblastoma, large-cell 2,855 | 6,234
glioblastoma 2,707 | 5,572
lung cancer 2,316 | 4,473
atypical teratoid / rhabdoid tumor 2,010 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 1,646 | 3,289
Breast cancer 1,534 | 3,098
malignant mesothelioma 1,515 | 3,163
invasive ductal carcinoma 1,481 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 1,472 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 1,453 | 2,956
pilocytic astrocytoma 1,446 | 3,086
oligodendroglioma 1,364 | 2,849
non-small cell lung cancer 1,336 | 2,798
primitive neuroectodermal tumor 1,332 | 3,031
pediatric high grade glioma 1,303 | 2,712
lung adenocarcinoma 1,257 | 2,714
ependymoma 1,256 | 2,514
lung carcinoma 1,222 | 2,844
pancreatic cancer 1,167 | 2,300
Cancer 1,153 | 2,346
subependymal giant cell astrocytoma 1,140 | 2,287
astrocytic glioma 1,076 | 2,241
pancreatic ductal adenocarcinoma liver metastasis 1,058 | 1,795
Carcinoma 1,052 | 2,147
Pick disease 984 | 1,893
ulcerative colitis 977 | 2,087
group 3 medulloblastoma 967 | 2,254
Multiple myeloma 958 | 1,327
adult high grade glioma 941 | 2,148
interstitial cystitis 940 | 2,299
group 4 medulloblastoma 895 | 1,875
astrocytoma 856 | 1,493
ductal carcinoma in situ 833 | 1,745
pituitary cancer 824 | 1,972
breast carcinoma 809 | 1,614
diabetes mellitus 798 | 1,663
cystic fibrosis 796 | 1,670
colon cancer 782 | 1,475
tuberculosis 743 | 1,563
acute quadriplegic myopathy 728 | 1,157
primary pancreatic ductal adenocarcinoma 727 | 1,271
juvenile dermatomyositis 706 | 1,189
sonic hedgehog group medulloblastoma 701 | 1,482
medulloblastoma 679 | 1,524
posterior fossa group A ependymoma 673 | 1,511
adrenocortical carcinoma 660 | 1,427
dermatomyositis 645 | 966
Rheumatoid Arthritis 582 | 1,170
Waldenstrons macroglobulinemia 568 | 764
posterior fossa group B ependymoma 567 | 1,530
spina bifida 507 | 1,064
atypical teratoid/rhabdoid tumor 476 | 1,095
nasopharyngeal carcinoma 458 | 1,056
cutaneous lupus erythematosus 448 | 1,056
gastric carcinoma 434 | 832
Atopic dermatitis 432 | 944
esophageal adenocarcinoma 417 | 737
active Crohn's disease 416 | 918
acute myeloid leukemia 410 | 785
non primary Sjogren syndrome sicca 404 | 840
Duchenne muscular dystrophy 402 | 602
primary Sjogren syndrome 381 | 788
progressive supranuclear palsy 355 | 674
aldosterone-producing adenoma 339 | 664
Alzheimer's disease 334 | 644
tuberculosis and treatment for 6 months 323 | 686
autosomal dominant Emery-Dreifuss muscular dystrophy 320 | 499
Down syndrome 313 | 548
Intellectual disability 300 | 573
pancreatic carcinoma 281 | 567
fibroadenoma 269 | 557
IGA Glomerulonephritis 261 | 454
Amyotrophic Lateral Sclerosis 259 | 432
Obesity 259 | 616
hepatocellular carcinoma 257 | 550
Neurodegenerative disease 254 | 383
Prostatic Neoplasms 238 | 471
hereditary spastic paraplegia 230 | 313
mucosa-associated lymphoid tissue lymphoma 226 | 480
Mammary Neoplasms 211 | 410
gastric cancer 205 | 436
Schizophrenia 203 | 503
Endometriosis 202 | 535
active ulcerative colitis 194 | 477
Multiple Sclerosis 192 | 498
chronic rhinosinusitis 188 | 512
inflammatory breast cancer 185 | 404
Parkinson's disease 181 | 364
Kidney disease 179 | 397
Polycystic Ovary Syndrome 175 | 334
non-small cell lung carcinoma 175 | 413
interstitial lung disease 165 | 292
Stomach Neoplasms 161 | 282
sarcoidosis 161 | 368
Vascular disease 158 | 281
glioblastoma multiforme 156 | 347
urothelial carcinoma 154 | 318

Tissue

Urinary Tract 7,600 | 18,443
Digestive Tract 7,589 | 18,472
Nervous System 7,588 | 18,560
Liver and Pancreas 7,584 | 18,135
Female tissues 7,583 | 18,646
Male tissues 7,579 | 17,968
Blood and immune system 7,578 | 17,994
Endocrine System 7,568 | 18,511
Cardiovascular System 7,557 | 17,957
Respiratory system 7,522 | 17,483
Skin and soft tissues 7,463 | 18,114

Target Family

Non-IDG 4,533 | 11,969
Enzyme 2,064 | 4,146
Kinase 388 | 634
Transcription Factor 241 | 1,400
Transporter 135 | 473
Epigenetic 93 | 242
Ion Channel 82 | 341
GPCR 36 | 408
TF/Epigenetic 11 | 38
Nuclear Receptor 9 | 48
oGPCR 8 | 421

HPM Tissue

Adult Urinary Bladder 7,600 | 7,600
Adult Testis 10,842 | 10,842
Adult Ovary 10,200 | 10,200
Adult Retina 10,123 | 10,123
CD8 Cells 9,848 | 9,848
Fetal Heart 9,238 | 9,238
Adult Pancreas 9,174 | 9,174
Fetal Ovary 9,126 | 9,126
Adult Liver 9,121 | 9,121
B Cells 9,090 | 9,090
Adult Frontal Cortex 9,053 | 9,053
Adult Prostate 8,962 | 8,962
Fetal Gut 8,647 | 8,647
NK Cells 8,480 | 8,480
Adult Adrenal 8,478 | 8,478
Fetal Liver 8,409 | 8,409
Adult Rectum 8,031 | 8,031
Fetal Testis 7,960 | 7,960
Adult Colon 7,920 | 7,920
Fetal Brain 7,870 | 7,870
CD4 Cells 7,778 | 7,778
Adult Gallbladder 7,618 | 7,618
Adult Spinal Cord 7,598 | 7,598
Monocytes 7,426 | 7,426
Adult Kidney 6,727 | 6,727
Adult Lung 6,668 | 6,668
Adult Heart 6,509 | 6,509
Platelets 6,132 | 6,132
Placenta 6,086 | 6,086
Adult Esophagus 4,938 | 4,938

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.50722 29.2 46
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
F-box/LRR-repeat protein 21 FBXL21 Tdark Non-IDG 0.00000 0
Epithelial membrane protein 3 EMP3 Tbio Non-IDG -1.64647 44.8 131
Hydroxymethylglutaryl-CoA synthase, mitochondrial HMGCS2 Tbio Enzyme -1.69372 46.6 95
Phosphoglycerate mutase 2 PGAM2 Tbio Enzyme -1.54638 36.2 160
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.04868 9.00 130
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
Splicing regulatory glutamine/lysine-rich protein 1 SREK1 Tdark Non-IDG -0.37946 3.77 39
Protein Mpv17 MPV17 Tbio Non-IDG -1.63162 40.5 114