Development Level

Tbio 4,994 | 10,625
Tdark 1,363 | 7,003
Tchem 988 | 1,890
Tclin 256 | 602

Collection

Eligible Kinase Proteins 60 | 134
Eligible Ion Channel Proteins 26 | 117
Eligible non-olfactory GPCR Proteins 14 | 143

IMPC Term

preweaning lethality, complete... 356 | 633
preweaning lethality, incomple... 131 | 260
decreased lean body mass 111 | 195
embryonic lethality prior to t... 107 | 187
abnormal behavior 106 | 226
decreased total body fat amoun... 103 | 186
decreased body weight 93 | 174
embryonic lethality prior to o... 91 | 148
decreased bone mineral content 83 | 157
increased circulating alkaline... 72 | 119
abnormal bone structure 69 | 131
decreased bone mineral density 66 | 126
abnormal embryo size 63 | 112
decreased circulating glucose ... 63 | 121
increased or absent threshold ... 63 | 128
decreased grip strength 61 | 123
decreased body length 60 | 108
hyperactivity 56 | 108
increased lean body mass 54 | 107
abnormal retina morphology 51 | 100
increased mean corpuscular hem... 50 | 93
increased bone mineral content 46 | 92
decreased circulating choleste... 44 | 85
decreased circulating HDL chol... 43 | 77
decreased circulating triglyce... 41 | 83
abnormal lens morphology 40 | 73
decreased circulating serum al... 40 | 79
short tibia 40 | 82
decreased circulating insulin ... 39 | 75
hypoactivity 39 | 89
decreased mean corpuscular vol... 38 | 50
enlarged heart 38 | 111
increased grip strength 38 | 83
increased fasted circulating g... 37 | 68
increased mean corpuscular vol... 37 | 91
prenatal lethality prior to he... 33 | 64
male infertility 32 | 62
increased circulating sodium l... 31 | 71
abnormal sleep behavior 30 | 63
decreased lumbar vertebrae num... 30 | 62
impaired glucose tolerance 29 | 52
abnormal bone mineralization 27 | 55
abnormal retinal pigmentation 27 | 61
increased hemoglobin content 27 | 45
thrombocytopenia 27 | 46
decreased fasted circulating g... 26 | 49
improved glucose tolerance 26 | 56
increased bone mineral density 26 | 52
increased circulating HDL chol... 26 | 63
increased circulating choleste... 26 | 53
increased exploration in new e... 26 | 56
abnormal behavioral response t... 25 | 52
abnormal coat/hair pigmentatio... 25 | 54
decreased leukocyte cell numbe... 25 | 54
decreased rib number 25 | 59
decreased caudal vertebrae num... 24 | 49
increased body weight 24 | 42
increased sacral vertebrae num... 24 | 62
decreased circulating alanine ... 23 | 53
decreased hemoglobin content 23 | 53
increased total body fat amoun... 23 | 57
decreased circulating total pr... 22 | 41
decreased mean corpuscular hem... 22 | 34
decreased startle reflex 22 | 48
increased blood urea nitrogen ... 22 | 44
abnormal gait 21 | 51
decreased eosinophil cell numb... 21 | 41
decreased heart weight 21 | 44
decreased prepulse inhibition 21 | 52
abnormal neural tube closure 20 | 37
abnormal seminal vesicle morph... 20 | 47
increased circulating chloride... 20 | 43
decreased circulating LDL chol... 19 | 37
decreased circulating alkaline... 19 | 41
increased heart weight 19 | 37
increased hematocrit 19 | 36
increased leukocyte cell numbe... 19 | 37
cardiovascular system phenotyp... 18 | 35
decreased circulating calcium ... 18 | 33
decreased circulating fructosa... 18 | 31
decreased neutrophil cell numb... 18 | 37
increased rib number 18 | 41
abnormal eye morphology 17 | 38
decreased circulating aspartat... 17 | 27
decreased circulating free fat... 17 | 39
small testis 17 | 37
abnormal cranium morphology 16 | 32
abnormal heart morphology 16 | 51
abnormal testis morphology 16 | 30
decreased blood urea nitrogen ... 16 | 31
decreased erythrocyte cell num... 16 | 43
limb grasping 16 | 35
decreased circulating creatini... 15 | 31
decreased circulating iron lev... 15 | 25
decreased threshold for audito... 15 | 32
embryonic growth retardation 15 | 28
increased circulating calcium ... 15 | 32
increased circulating phosphat... 15 | 24
increased circulating potassiu... 15 | 31
increased startle reflex 15 | 38

Disease

ovarian cancer 4,444 | 8,484
osteosarcoma 3,612 | 7,933
psoriasis 2,947 | 6,685
medulloblastoma, large-cell 2,855 | 6,234
glioblastoma 2,707 | 5,572
lung cancer 2,313 | 4,466
atypical teratoid / rhabdoid tumor 2,010 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 1,646 | 3,289
Breast cancer 1,534 | 3,094
malignant mesothelioma 1,515 | 3,162
invasive ductal carcinoma 1,481 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 1,472 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 1,453 | 2,956
pilocytic astrocytoma 1,446 | 3,086
oligodendroglioma 1,364 | 2,849
non-small cell lung cancer 1,336 | 2,798
primitive neuroectodermal tumor 1,332 | 3,031
pediatric high grade glioma 1,303 | 2,712
lung adenocarcinoma 1,257 | 2,713
ependymoma 1,256 | 2,514
lung carcinoma 1,222 | 2,844
pancreatic cancer 1,167 | 2,300
Cancer 1,153 | 2,346
subependymal giant cell astrocytoma 1,140 | 2,287
astrocytic glioma 1,076 | 2,241
pancreatic ductal adenocarcinoma liver metastasis 1,058 | 1,795
Carcinoma 1,052 | 2,147
Pick disease 984 | 1,893
ulcerative colitis 977 | 2,087
group 3 medulloblastoma 967 | 2,254
Multiple myeloma 959 | 1,327
adult high grade glioma 941 | 2,148
interstitial cystitis 940 | 2,299
group 4 medulloblastoma 895 | 1,875
astrocytoma 856 | 1,493
ductal carcinoma in situ 833 | 1,745
pituitary cancer 824 | 1,972
breast carcinoma 809 | 1,614
diabetes mellitus 798 | 1,663
cystic fibrosis 795 | 1,665
colon cancer 782 | 1,475
tuberculosis 741 | 1,557
acute quadriplegic myopathy 728 | 1,157
primary pancreatic ductal adenocarcinoma 727 | 1,271
juvenile dermatomyositis 706 | 1,189
sonic hedgehog group medulloblastoma 701 | 1,482
medulloblastoma 679 | 1,524
posterior fossa group A ependymoma 673 | 1,511
adrenocortical carcinoma 660 | 1,427
dermatomyositis 645 | 933
Rheumatoid Arthritis 582 | 1,160
Waldenstrons macroglobulinemia 569 | 765
posterior fossa group B ependymoma 567 | 1,530
spina bifida 507 | 1,064
atypical teratoid/rhabdoid tumor 476 | 1,095
nasopharyngeal carcinoma 458 | 1,056
cutaneous lupus erythematosus 448 | 1,056
gastric carcinoma 434 | 832
Atopic dermatitis 432 | 944
esophageal adenocarcinoma 417 | 737
active Crohn's disease 416 | 918
acute myeloid leukemia 408 | 780
non primary Sjogren syndrome sicca 404 | 840
Duchenne muscular dystrophy 402 | 602
primary Sjogren syndrome 382 | 789
progressive supranuclear palsy 355 | 674
aldosterone-producing adenoma 339 | 664
Alzheimer's disease 334 | 644
tuberculosis and treatment for 6 months 323 | 686
autosomal dominant Emery-Dreifuss muscular dystrophy 320 | 499
Down syndrome 313 | 548
Intellectual disability 300 | 573
pancreatic carcinoma 281 | 567
fibroadenoma 269 | 557
IGA Glomerulonephritis 261 | 454
Amyotrophic Lateral Sclerosis 259 | 431
Obesity 259 | 616
Neurodegenerative disease 254 | 383
hepatocellular carcinoma 247 | 532
Prostatic Neoplasms 238 | 471
hereditary spastic paraplegia 230 | 313
mucosa-associated lymphoid tissue lymphoma 226 | 480
Mammary Neoplasms 211 | 410
gastric cancer 203 | 430
Endometriosis 202 | 535
Schizophrenia 202 | 501
active ulcerative colitis 194 | 477
Multiple Sclerosis 192 | 498
chronic rhinosinusitis 188 | 512
inflammatory breast cancer 185 | 404
Parkinson's disease 181 | 364
Kidney disease 179 | 396
non-small cell lung carcinoma 175 | 413
Polycystic Ovary Syndrome 174 | 332
interstitial lung disease 164 | 291
Stomach Neoplasms 161 | 282
sarcoidosis 160 | 358
Vascular disease 158 | 281
glioblastoma multiforme 156 | 347
urothelial carcinoma 154 | 318

Tissue

Urinary Tract 7,601 | 18,444
Digestive Tract 7,590 | 18,473
Nervous System 7,589 | 18,561
Liver and Pancreas 7,585 | 18,136
Female tissues 7,584 | 18,647
Male tissues 7,580 | 17,969
Blood and immune system 7,579 | 17,995
Endocrine System 7,569 | 18,512
Cardiovascular System 7,558 | 17,958
Respiratory system 7,523 | 17,484
Skin and soft tissues 7,464 | 18,115

Target Family

Non-IDG 4,533 | 11,971
Enzyme 2,065 | 4,146
Kinase 388 | 634
Transcription Factor 241 | 1,400
Transporter 135 | 473
Epigenetic 93 | 242
Ion Channel 82 | 341
GPCR 36 | 406
TF/Epigenetic 11 | 38
Nuclear Receptor 9 | 48
oGPCR 8 | 421

HPM Tissue

Adult Urinary Bladder 7,601 | 7,601
Adult Testis 10,843 | 10,843
Adult Ovary 10,201 | 10,201
Adult Retina 10,124 | 10,124
CD8 Cells 9,849 | 9,849
Fetal Heart 9,239 | 9,239
Adult Pancreas 9,175 | 9,175
Fetal Ovary 9,127 | 9,127
Adult Liver 9,122 | 9,122
B Cells 9,091 | 9,091
Adult Frontal Cortex 9,054 | 9,054
Adult Prostate 8,963 | 8,963
Fetal Gut 8,648 | 8,648
NK Cells 8,481 | 8,481
Adult Adrenal 8,479 | 8,479
Fetal Liver 8,410 | 8,410
Adult Rectum 8,032 | 8,032
Fetal Testis 7,961 | 7,961
Adult Colon 7,921 | 7,921
Fetal Brain 7,871 | 7,871
CD4 Cells 7,779 | 7,779
Adult Gallbladder 7,619 | 7,619
Adult Spinal Cord 7,599 | 7,599
Monocytes 7,427 | 7,427
Adult Kidney 6,728 | 6,728
Adult Lung 6,669 | 6,669
Adult Heart 6,510 | 6,510
Platelets 6,133 | 6,133
Placenta 6,087 | 6,087
Adult Esophagus 4,939 | 4,939

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.31593 2169.0 108
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
ATP synthase F(0) complex subunit C3, mitochondrial ATP5G3 Tdark Enzyme -1.10871 11.9 27
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89