Development Level

Tbio 7,006 | 11,178
Tdark 2,322 | 6,569
Tchem 1,202 | 1,885
Tclin 306 | 612

Collection

Kinase: IDG Consortium (Target... 91 | 125
Ion Channel: IDG Consortium (T... 33 | 99
Kinase: IDG Consortium (Comple... 29 | 37
GPCR: IDG Consortium (Targets) 16 | 126
GPCR: IDG Consortium (Complete... 5 | 25

IMPC Phenotype

preweaning lethality, complete... 776 | 979
preweaning lethality, incomple... 344 | 499
embryonic lethality prior to t... 217 | 278
embryonic lethality prior to o... 210 | 239
abnormal behavior 197 | 298
abnormal embryo size 158 | 220
decreased total body fat amoun... 134 | 207
abnormal bone structure 132 | 187
decreased body weight 117 | 161
increased lean body mass 112 | 172
enlarged heart 106 | 210
decreased vertical activity 101 | 208
hyperactivity 99 | 148
decreased bone mineral content 98 | 151
abnormal heart morphology 88 | 162
increased circulating alkaline... 88 | 122
increased total body fat amoun... 88 | 134
hypoactivity 87 | 132
male infertility 87 | 123
decreased lean body mass 86 | 135
decreased bone mineral density 83 | 126
embryonic growth retardation 82 | 106
decreased circulating glucose ... 81 | 126
decreased grip strength 79 | 116
increased startle reflex 75 | 112
decreased body length 68 | 101
increased bone mineral content 68 | 108
decreased circulating choleste... 67 | 93
short tibia 67 | 97
increased mean corpuscular hem... 65 | 96
prenatal lethality prior to he... 64 | 87
cataract 62 | 92
increased or absent threshold ... 62 | 101
increased mean corpuscular vol... 61 | 92
decreased mean corpuscular vol... 60 | 79
increased circulating HDL chol... 57 | 80
abnormal seminal vesicle morph... 56 | 114
abnormal lens morphology 54 | 81
decreased prepulse inhibition 53 | 82
abnormal behavioral response t... 52 | 66
decreased circulating serum al... 52 | 82
decreased circulating triglyce... 51 | 79
impaired glucose tolerance 51 | 75
increased fasted circulating g... 51 | 76
abnormal sleep behavior 50 | 70
decreased leukocyte cell numbe... 50 | 73
increased circulating choleste... 49 | 66
abnormal retina morphology 48 | 71
decreased circulating HDL chol... 47 | 68
decreased startle reflex 47 | 75
improved glucose tolerance 47 | 79
decreased lymphocyte cell numb... 46 | 83
increased bone mineral density 46 | 72
increased heart weight 46 | 62
increased circulating sodium l... 45 | 71
decreased erythrocyte cell num... 44 | 62
decreased hemoglobin content 44 | 68
abnormal eye morphology 43 | 68
abnormal gait 43 | 69
decreased circulating insulin ... 43 | 76
abnormal coat-hair pigmentatio... 42 | 64
decreased fasted circulating g... 41 | 65
thrombocytopenia 40 | 56
decreased caudal vertebrae num... 38 | 53
decreased circulating alkaline... 38 | 46
edema 38 | 59
female infertility 36 | 60
small testis 36 | 58
decreased circulating total pr... 35 | 49
increased blood urea nitrogen ... 35 | 48
increased hematocrit 35 | 46
small superior vagus ganglion 35 | 74
decreased mean corpuscular hem... 34 | 50
increased monocyte cell number 34 | 63
increased hemoglobin content 33 | 45
increased neutrophil cell numb... 33 | 46
abnormal kidney morphology 32 | 65
decreased circulating alanine ... 32 | 47
increased circulating chloride... 32 | 41
increased erythrocyte cell num... 32 | 39
increased leukocyte cell numbe... 32 | 47
increased mean platelet volume 32 | 45
abnormal skin morphology 31 | 50
decreased blood urea nitrogen ... 31 | 51
decreased circulating LDL chol... 31 | 38
abnormal spleen morphology 30 | 55
decreased neutrophil cell numb... 30 | 42
increased circulating triglyce... 30 | 42
increased grip strength 29 | 41
tremors 29 | 39
decreased hematocrit 28 | 46
decreased red blood cell distr... 27 | 41
hydrometra 27 | 53
persistence of hyaloid vascula... 27 | 33
abnormal embryo turning 26 | 31
decreased circulating aspartat... 26 | 34
decreased circulating calcium ... 26 | 36
decreased mean corpuscular hem... 25 | 31
increased red blood cell distr... 25 | 34
prolonged QT interval 25 | 38

Disease

Carcinoma 6,792 | 11,192
ovarian cancer 5,782 | 8,297
osteosarcoma 4,920 | 7,766
medulloblastoma, large-cell 3,865 | 6,086
psoriasis 3,821 | 6,514
glioblastoma 3,617 | 5,635
atypical teratoid / rhabdoid tumor 3,141 | 4,971
lung cancer 3,062 | 4,607
ependymoma 2,880 | 4,559
group 3 medulloblastoma 2,589 | 4,002
Breast cancer 2,252 | 3,469
adult high grade glioma 2,225 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 2,073 | 3,204
malignant mesothelioma 2,038 | 3,135
intraductal papillary-mucinous carcinoma (IPMC) 1,870 | 2,902
primitive neuroectodermal tumor 1,836 | 2,957
invasive ductal carcinoma 1,816 | 2,867
Astrocytoma, Pilocytic 1,793 | 3,006
intraductal papillary-mucinous adenoma (IPMA) 1,792 | 2,872
Kidney cancer 1,767 | 2,548
oligodendroglioma 1,766 | 2,768
non-small cell lung cancer 1,714 | 2,799
astrocytic glioma 1,640 | 2,530
lung adenocarcinoma 1,572 | 2,627
lung carcinoma 1,514 | 2,755
pancreatic cancer 1,459 | 2,322
Cancer 1,449 | 2,388
subependymal giant cell astrocytoma 1,441 | 2,230
pancreatic ductal adenocarcinoma liver metastasis 1,411 | 1,911
Pick disease 1,296 | 1,856
tuberculosis 1,184 | 1,963
group 4 medulloblastoma 1,170 | 1,806
interstitial cystitis 1,111 | 2,237
Multiple myeloma 1,105 | 1,296
pituitary cancer 1,089 | 1,915
ductal carcinoma in situ 1,042 | 1,686
ulcerative colitis 1,023 | 1,765
breast carcinoma 1,010 | 1,589
Autosomal recessive predisposition 976 | 1,407
diabetes mellitus 965 | 1,683
cystic fibrosis 947 | 1,629
colon cancer 913 | 1,428
adrenocortical carcinoma 890 | 1,385
acute quadriplegic myopathy 878 | 1,133
juvenile dermatomyositis 850 | 1,147
astrocytoma 808 | 1,113
dermatomyositis 757 | 941
primary pancreatic ductal adenocarcinoma 735 | 1,071
Rheumatoid arthritis 725 | 1,156
Intellectual disability 713 | 998
pediatric high grade glioma 686 | 1,035
spina bifida 666 | 1,053
Schizophrenia 661 | 1,136
Waldenstrons macroglobulinemia 619 | 742
nasopharyngeal carcinoma 600 | 1,024
Epilepsy 559 | 775
non primary Sjogren syndrome sicca 555 | 861
cutaneous lupus erythematosus 541 | 1,016
Atopic dermatitis 536 | 915
acute myeloid leukemia 526 | 760
active Crohn's disease 524 | 882
gastric carcinoma 493 | 781
progressive supranuclear palsy 472 | 656
Cognitive delay 470 | 596
Global developmental delay 470 | 596
Mental and motor retardation 470 | 596
Liver Cirrhosis, Experimental 466 | 733
Dull intelligence 454 | 634
Low intelligence 454 | 634
Mental Retardation 454 | 634
Mental deficiency 454 | 634
Poor school performance 454 | 634
Duchenne muscular dystrophy 443 | 587
esophageal adenocarcinoma 443 | 696
primary Sjogren syndrome 439 | 710
Seizures 437 | 584
medulloblastoma 437 | 702
Muscle hypotonia 435 | 562
aldosterone-producing adenoma 429 | 646
Alzheimer's disease 415 | 640
active ulcerative colitis 413 | 736
Melanoma 410 | 689
Liver cancer 405 | 589
pancreatic carcinoma 370 | 555
Short stature 368 | 514
autosomal dominant Emery-Dreifuss muscular dystrophy 361 | 492
Obesity 360 | 655
Bipolar Disorder 355 | 646
hepatocellular carcinoma 343 | 536
Amyotrophic lateral sclerosis 328 | 437
Down syndrome 328 | 480
Neurodegenerative disease 323 | 402
Prostatic Neoplasms 309 | 472
Endometriosis 303 | 521
sonic hedgehog group medulloblastoma 298 | 459
fibroadenoma 293 | 538
Small head 291 | 366
tuberculosis and treatment for 6 months 287 | 399
chronic rhinosinusitis 282 | 505
gastric cancer 282 | 445

Tissue

Endocrine System 10,686 | 18,159
Female tissues 10,429 | 17,400
Digestive Tract 10,395 | 17,369
Skin and soft tissues 10,384 | 17,230
Male tissues 10,354 | 17,142
Blood and immune system 10,269 | 16,909
Liver and Pancreas 10,218 | 16,750
Nervous System 10,215 | 16,725
Urinary Tract 10,198 | 16,678
Respiratory system 10,136 | 16,393
Cardiovascular System 9,732 | 15,192

Target Family

Non-IDG 6,385 | 12,091
Enzyme 2,739 | 4,145
Transcription Factor 594 | 1,400
Kinase 503 | 634
Transporter 213 | 473
Epigenetic 177 | 242
Ion Channel 117 | 344
GPCR 57 | 408
TF/Epigenetic 20 | 38
Nuclear Receptor 16 | 48
oGPCR 15 | 421

HPM Tissue

Adult Testis 10,836 | 10,836
Adult Ovary 10,192 | 10,192
Adult Retina 10,115 | 10,115
CD8 Cells 9,840 | 9,840
Fetal Heart 9,228 | 9,228
Adult Pancreas 9,168 | 9,168
Fetal Ovary 9,118 | 9,118
Adult Liver 9,113 | 9,113
B Cells 9,086 | 9,086
Adult Frontal Cortex 9,048 | 9,048
Adult Prostate 8,952 | 8,952
Fetal Gut 8,640 | 8,640
Adult Adrenal 8,475 | 8,475
NK Cells 8,475 | 8,475
Fetal Liver 8,402 | 8,402
Adult Rectum 8,022 | 8,022
Fetal Testis 7,955 | 7,955
Adult Colon 7,915 | 7,915
Fetal Brain 7,866 | 7,866
CD4 Cells 7,773 | 7,773
Adult Gallbladder 7,612 | 7,612
Adult Spinal Cord 7,594 | 7,594
Adult Urinary Bladder 7,592 | 7,592
Monocytes 7,422 | 7,422
Adult Kidney 6,723 | 6,723
Adult Lung 6,663 | 6,663
Adult Heart 6,506 | 6,506
Platelets 6,131 | 6,131
Placenta 6,083 | 6,083
Adult Esophagus 4,936 | 4,936

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15
DENN domain-containing protein 1A DENND1A Tbio Non-IDG -1.14835 13.7 90
Melanoma-associated antigen 9 MAGEA9B Tbio Non-IDG -1.32496 23.3 213
Melanoma-associated antigen 11 MAGEA11 Tbio Non-IDG -1.28291 22.2 180
Melanoma-associated antigen 12 MAGEA12 Tbio Non-IDG -1.35716 21.7 116
Melanoma-associated antigen B1 MAGEB1 Tbio Non-IDG -0.95979 9.05 218
General transcription factor IIE subunit 1 GTF2E1 Tbio Non-IDG 0.16 0.68 153
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.03938 994.7 101
Histone H2B type 2-E HIST2H2BE Tbio Non-IDG -3.48425 2920.0 135