Development Level

Tbio 5,587 | 11,651
Tdark 1,417 | 6,593
Tchem 758 | 1,388
Tclin 260 | 612

Collection

Kinase: IDG Consortium (Target... 61 | 125
Ion Channel: IDG Consortium (T... 24 | 99
Kinase: IDG Consortium (Comple... 22 | 37
GPCR: IDG Consortium (Targets) 8 | 126
GPCR: IDG Consortium (Complete... 4 | 25

IMPC Phenotype

preweaning lethality, complete... 599 | 979
preweaning lethality, incomple... 244 | 499
embryonic lethality prior to o... 160 | 239
embryonic lethality prior to t... 160 | 278
abnormal behavior 141 | 298
abnormal embryo size 123 | 220
decreased total body fat amoun... 104 | 207
abnormal bone structure 86 | 187
decreased body weight 85 | 161
enlarged heart 75 | 210
increased lean body mass 74 | 172
decreased vertical activity 73 | 208
decreased bone mineral content 72 | 151
embryonic growth retardation 68 | 106
hypoactivity 68 | 132
increased circulating alkaline... 68 | 122
hyperactivity 66 | 148
decreased circulating glucose ... 64 | 126
increased total body fat amoun... 60 | 134
increased startle reflex 57 | 112
decreased bone mineral density 56 | 126
abnormal heart morphology 55 | 162
decreased grip strength 55 | 116
decreased lean body mass 55 | 135
increased bone mineral content 54 | 108
increased or absent threshold ... 52 | 101
male infertility 51 | 123
short tibia 51 | 97
increased mean corpuscular hem... 50 | 96
prenatal lethality prior to he... 50 | 87
decreased mean corpuscular vol... 46 | 79
increased mean corpuscular vol... 46 | 92
decreased circulating choleste... 45 | 93
abnormal seminal vesicle morph... 44 | 114
decreased prepulse inhibition 44 | 82
decreased body length 43 | 101
increased fasted circulating g... 41 | 76
cataract 40 | 92
abnormal lens morphology 38 | 81
decreased circulating HDL chol... 38 | 68
decreased circulating serum al... 36 | 82
decreased leukocyte cell numbe... 36 | 73
decreased circulating triglyce... 35 | 79
decreased fasted circulating g... 35 | 65
decreased lymphocyte cell numb... 35 | 83
improved glucose tolerance 35 | 79
increased circulating choleste... 35 | 66
abnormal retina morphology 34 | 71
decreased startle reflex 34 | 75
impaired glucose tolerance 34 | 75
increased heart weight 34 | 62
abnormal behavioral response t... 33 | 66
decreased circulating insulin ... 33 | 76
increased circulating HDL chol... 33 | 80
increased circulating sodium l... 32 | 71
abnormal sleep behavior 30 | 70
increased bone mineral density 30 | 72
thrombocytopenia 30 | 56
abnormal eye morphology 29 | 68
abnormal gait 29 | 69
decreased caudal vertebrae num... 29 | 53
decreased circulating alkaline... 29 | 46
decreased neutrophil cell numb... 28 | 42
abnormal coat-hair pigmentatio... 27 | 64
decreased erythrocyte cell num... 27 | 62
edema 27 | 59
increased blood urea nitrogen ... 27 | 48
decreased circulating total pr... 26 | 49
decreased hemoglobin content 26 | 68
increased erythrocyte cell num... 26 | 39
abnormal kidney morphology 25 | 65
abnormal skin morphology 25 | 50
decreased mean corpuscular hem... 25 | 50
increased monocyte cell number 25 | 63
decreased blood urea nitrogen ... 24 | 51
increased grip strength 24 | 41
increased hematocrit 24 | 46
increased hemoglobin content 24 | 45
increased mean platelet volume 24 | 45
small testis 24 | 58
small superior vagus ganglion 23 | 74
decreased circulating LDL chol... 22 | 38
decreased circulating aspartat... 22 | 34
decreased mean corpuscular hem... 22 | 31
increased circulating chloride... 22 | 41
increased leukocyte cell numbe... 22 | 47
increased neutrophil cell numb... 22 | 46
decreased circulating alanine ... 21 | 47
decreased red blood cell distr... 21 | 41
enlarged spleen 21 | 41
female infertility 21 | 60
increased circulating triglyce... 21 | 42
limb grasping 21 | 41
abnormal spleen morphology 20 | 55
cardiovascular system phenotyp... 20 | 36
decreased hematocrit 20 | 46
pallor 20 | 34
abnormal cornea morphology 19 | 31
decreased circulating calcium ... 19 | 36
increased circulating calcium ... 19 | 34

Disease

Carcinoma 5,178 | 11,493
ovarian cancer 4,577 | 8,520
osteosarcoma 3,793 | 7,950
psoriasis 3,063 | 6,694
medulloblastoma, large-cell 2,953 | 6,241
glioblastoma 2,900 | 5,792
lung cancer 2,507 | 4,740
atypical teratoid / rhabdoid tumor 2,440 | 5,112
ependymoma 2,200 | 4,679
group 3 medulloblastoma 1,938 | 4,104
Breast cancer 1,804 | 3,578
adult high grade glioma 1,738 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 1,720 | 3,291
malignant mesothelioma 1,621 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 1,550 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 1,520 | 2,955
invasive ductal carcinoma 1,520 | 2,951
Astrocytoma, Pilocytic 1,464 | 3,081
primitive neuroectodermal tumor 1,412 | 3,035
oligodendroglioma 1,401 | 2,850
non-small cell lung cancer 1,399 | 2,890
Kidney cancer 1,381 | 2,613
lung adenocarcinoma 1,339 | 2,716
astrocytic glioma 1,293 | 2,597
Cancer 1,289 | 2,499
lung carcinoma 1,269 | 2,843
pancreatic cancer 1,260 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1,202 | 1,962
subependymal giant cell astrocytoma 1,153 | 2,287
Pick disease 998 | 1,894
Multiple myeloma 987 | 1,332
interstitial cystitis 970 | 2,312
tuberculosis 946 | 2,010
group 4 medulloblastoma 902 | 1,855
ulcerative colitis 885 | 1,819
ductal carcinoma in situ 866 | 1,745
diabetes mellitus 851 | 1,728
colon cancer 839 | 1,478
pituitary cancer 835 | 1,972
breast carcinoma 827 | 1,638
Autosomal recessive predisposition 816 | 1,442
cystic fibrosis 816 | 1,696
acute quadriplegic myopathy 734 | 1,158
juvenile dermatomyositis 696 | 1,187
astrocytoma 686 | 1,146
adrenocortical carcinoma 668 | 1,428
dermatomyositis 661 | 966
primary pancreatic ductal adenocarcinoma 614 | 1,109
Rheumatoid arthritis 613 | 1,191
Waldenstrons macroglobulinemia 581 | 765
pediatric high grade glioma 563 | 1,064
Schizophrenia 554 | 1,160
Intellectual disability 546 | 1,016
spina bifida 499 | 1,074
cutaneous lupus erythematosus 477 | 1,057
nasopharyngeal carcinoma 461 | 1,058
non primary Sjogren syndrome sicca 460 | 891
active Crohn's disease 439 | 922
Epilepsy 436 | 792
Liver Cirrhosis, Experimental 431 | 769
acute myeloid leukemia 428 | 783
Atopic dermatitis 416 | 952
gastric carcinoma 412 | 807
esophageal adenocarcinoma 408 | 737
Duchenne muscular dystrophy 392 | 601
primary Sjogren syndrome 379 | 735
Cognitive delay 378 | 608
Global developmental delay 378 | 608
Mental and motor retardation 378 | 608
progressive supranuclear palsy 370 | 676
Dull intelligence 363 | 645
Low intelligence 363 | 645
Mental Retardation 363 | 645
Mental deficiency 363 | 645
Poor school performance 363 | 645
Alzheimer's disease 360 | 658
Muscle hypotonia 358 | 571
active ulcerative colitis 346 | 764
Seizures 344 | 596
aldosterone-producing adenoma 343 | 665
Liver cancer 335 | 604
Melanoma 332 | 711
medulloblastoma 331 | 720
autosomal dominant Emery-Dreifuss muscular dystrophy 326 | 510
Bipolar Disorder 305 | 666
Obesity 296 | 678
Down syndrome 295 | 499
Short stature 295 | 531
pancreatic carcinoma 295 | 562
hepatocellular carcinoma 273 | 547
Amyotrophic lateral sclerosis 268 | 451
Prostatic Neoplasms 264 | 495
fibroadenoma 258 | 559
Neurodegenerative disease 257 | 414
gastric cancer 239 | 459
mucosa-associated lymphoid tissue lymphoma 238 | 484
sonic hedgehog group medulloblastoma 238 | 467
Breast Neoplasms 235 | 445
Failure to gain weight 229 | 365
Pediatric failure to thrive 229 | 365

Tissue

Endocrine System 7,909 | 18,159
Female tissues 7,811 | 17,400
Digestive Tract 7,802 | 17,369
Skin and soft tissues 7,791 | 17,230
Male tissues 7,749 | 17,142
Blood and immune system 7,707 | 16,909
Liver and Pancreas 7,687 | 16,750
Urinary Tract 7,676 | 16,678
Nervous System 7,658 | 16,725
Respiratory system 7,586 | 16,393
Cardiovascular System 7,344 | 15,192

Target Family

Non-IDG 4,685 | 12,091
Enzyme 2,136 | 4,145
Transcription Factor 411 | 1,400
Kinase 389 | 634
Transporter 136 | 473
Epigenetic 109 | 242
Ion Channel 93 | 344
GPCR 35 | 408
TF/Epigenetic 13 | 38
Nuclear Receptor 9 | 48
oGPCR 6 | 421

HPM Tissue

Adult Rectum 8,022 | 8,022
Adult Testis 10,836 | 10,836
Adult Ovary 10,192 | 10,192
Adult Retina 10,115 | 10,115
CD8 Cells 9,840 | 9,840
Fetal Heart 9,228 | 9,228
Adult Pancreas 9,168 | 9,168
Fetal Ovary 9,118 | 9,118
Adult Liver 9,113 | 9,113
B Cells 9,086 | 9,086
Adult Frontal Cortex 9,048 | 9,048
Adult Prostate 8,952 | 8,952
Fetal Gut 8,640 | 8,640
Adult Adrenal 8,475 | 8,475
NK Cells 8,475 | 8,475
Fetal Liver 8,402 | 8,402
Fetal Testis 7,955 | 7,955
Adult Colon 7,915 | 7,915
Fetal Brain 7,866 | 7,866
CD4 Cells 7,773 | 7,773
Adult Gallbladder 7,612 | 7,612
Adult Spinal Cord 7,594 | 7,594
Adult Urinary Bladder 7,592 | 7,592
Monocytes 7,422 | 7,422
Adult Kidney 6,723 | 6,723
Adult Lung 6,663 | 6,663
Adult Heart 6,506 | 6,506
Platelets 6,131 | 6,131
Placenta 6,083 | 6,083
Adult Esophagus 4,936 | 4,936

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 215 ZNF215 Tdark Transcription Factor -0.51747 3.15 91
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
Calcium uptake protein 3, mitochondrial MICU3 Tdark Non-IDG -0.21085 1.14 50
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Serine/arginine-rich splicing factor 12 SRSF12 Tbio Non-IDG -0.09691 1.17 22
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123