Development Level

Tbio 5,169 | 10,625
Tdark 1,591 | 7,003
Tchem 1,017 | 1,890
Tclin 255 | 602

Collection

Eligible Kinase Proteins 66 | 134
Eligible Ion Channel Proteins 26 | 117
Eligible non-olfactory GPCR Proteins 8 | 143

IMPC Term

preweaning lethality, complete... 364 | 633
preweaning lethality, incomple... 127 | 260
abnormal behavior 111 | 226
embryonic lethality prior to t... 108 | 187
decreased total body fat amoun... 105 | 186
decreased lean body mass 102 | 195
embryonic lethality prior to o... 102 | 148
decreased body weight 95 | 174
decreased bone mineral content 78 | 157
increased circulating alkaline... 68 | 119
abnormal embryo size 67 | 112
abnormal bone structure 65 | 131
increased or absent threshold ... 63 | 128
decreased circulating glucose ... 61 | 121
decreased grip strength 61 | 123
decreased bone mineral density 59 | 126
decreased body length 58 | 108
increased lean body mass 56 | 107
abnormal retina morphology 52 | 100
increased mean corpuscular hem... 51 | 93
hyperactivity 50 | 108
increased bone mineral content 48 | 92
hypoactivity 44 | 89
decreased circulating HDL chol... 43 | 77
short tibia 43 | 82
decreased circulating choleste... 41 | 85
decreased circulating triglyce... 41 | 83
increased grip strength 41 | 83
abnormal lens morphology 40 | 73
increased fasted circulating g... 39 | 68
increased mean corpuscular vol... 39 | 91
decreased circulating serum al... 38 | 79
decreased mean corpuscular vol... 38 | 50
enlarged heart 37 | 111
prenatal lethality prior to he... 37 | 64
decreased circulating insulin ... 36 | 75
increased circulating sodium l... 33 | 71
abnormal sleep behavior 30 | 63
abnormal retinal pigmentation 29 | 61
decreased fasted circulating g... 29 | 49
decreased leukocyte cell numbe... 29 | 54
impaired glucose tolerance 28 | 52
increased circulating choleste... 28 | 53
increased exploration in new e... 28 | 56
male infertility 28 | 62
abnormal bone mineralization 26 | 55
decreased lumbar vertebrae num... 26 | 62
decreased prepulse inhibition 26 | 52
decreased rib number 26 | 59
increased bone mineral density 26 | 52
increased circulating HDL chol... 26 | 63
decreased caudal vertebrae num... 25 | 49
decreased circulating alkaline... 25 | 41
increased blood urea nitrogen ... 25 | 44
increased hemoglobin content 25 | 45
increased total body fat amoun... 25 | 57
thrombocytopenia 25 | 46
abnormal behavioral response t... 24 | 52
abnormal gait 24 | 51
decreased hemoglobin content 24 | 53
increased circulating chloride... 24 | 43
abnormal coat/hair pigmentatio... 23 | 54
decreased circulating alanine ... 23 | 53
improved glucose tolerance 23 | 56
increased body weight 23 | 42
increased heart weight 23 | 37
increased sacral vertebrae num... 23 | 62
decreased circulating LDL chol... 22 | 37
decreased circulating total pr... 22 | 41
abnormal neural tube closure 21 | 37
decreased eosinophil cell numb... 21 | 41
decreased heart weight 21 | 44
decreased mean corpuscular hem... 21 | 34
decreased startle reflex 21 | 48
decreased circulating fructosa... 20 | 31
decreased neutrophil cell numb... 20 | 37
abnormal seminal vesicle morph... 19 | 47
cardiovascular system phenotyp... 19 | 35
decreased circulating calcium ... 19 | 33
decreased circulating free fat... 19 | 39
decreased erythrocyte cell num... 19 | 43
increased hematocrit 19 | 36
abnormal eye morphology 18 | 38
limb grasping 18 | 35
increased circulating calcium ... 17 | 32
increased erythrocyte cell num... 17 | 26
increased leukocyte cell numbe... 17 | 37
small testis 17 | 37
decreased circulating aspartat... 16 | 27
decreased circulating creatini... 16 | 31
embryonic growth retardation 16 | 28
increased circulating creatini... 16 | 29
increased circulating phosphat... 16 | 24
increased rib number 16 | 41
abnormal testis morphology 15 | 30
decreased NK T cell number 15 | 28
decreased blood urea nitrogen ... 15 | 31
decreased circulating amylase ... 15 | 24
increased circulating potassiu... 15 | 31
tremors 15 | 34

Disease

ovarian cancer 4,564 | 8,484
osteosarcoma 3,797 | 7,933
psoriasis 3,067 | 6,685
medulloblastoma, large-cell 2,953 | 6,234
glioblastoma 2,793 | 5,572
lung cancer 2,410 | 4,466
atypical teratoid / rhabdoid tumor 2,077 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 1,721 | 3,289
malignant mesothelioma 1,584 | 3,162
Breast cancer 1,571 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 1,551 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 1,525 | 2,956
invasive ductal carcinoma 1,521 | 2,950
pilocytic astrocytoma 1,468 | 3,086
primitive neuroectodermal tumor 1,414 | 3,031
oligodendroglioma 1,401 | 2,849
non-small cell lung cancer 1,367 | 2,798
lung adenocarcinoma 1,340 | 2,713
pediatric high grade glioma 1,338 | 2,712
ependymoma 1,312 | 2,514
lung carcinoma 1,268 | 2,844
Cancer 1,223 | 2,346
pancreatic cancer 1,208 | 2,300
subependymal giant cell astrocytoma 1,152 | 2,287
astrocytic glioma 1,107 | 2,241
Carcinoma 1,102 | 2,147
pancreatic ductal adenocarcinoma liver metastasis 1,098 | 1,795
group 3 medulloblastoma 1,036 | 2,254
ulcerative colitis 1,032 | 2,087
Pick disease 996 | 1,893
Multiple myeloma 985 | 1,327
interstitial cystitis 971 | 2,299
adult high grade glioma 962 | 2,148
group 4 medulloblastoma 942 | 1,875
astrocytoma 870 | 1,493
ductal carcinoma in situ 868 | 1,745
colon cancer 838 | 1,475
pituitary cancer 837 | 1,972
diabetes mellitus 816 | 1,663
breast carcinoma 811 | 1,614
cystic fibrosis 800 | 1,665
tuberculosis 755 | 1,557
acute quadriplegic myopathy 732 | 1,157
primary pancreatic ductal adenocarcinoma 717 | 1,271
sonic hedgehog group medulloblastoma 717 | 1,482
medulloblastoma 711 | 1,524
juvenile dermatomyositis 695 | 1,189
posterior fossa group A ependymoma 672 | 1,511
adrenocortical carcinoma 670 | 1,427
dermatomyositis 659 | 933
Rheumatoid Arthritis 611 | 1,160
posterior fossa group B ependymoma 591 | 1,530
Waldenstrons macroglobulinemia 582 | 765
atypical teratoid/rhabdoid tumor 528 | 1,095
spina bifida 495 | 1,064
cutaneous lupus erythematosus 477 | 1,056
nasopharyngeal carcinoma 461 | 1,056
non primary Sjogren syndrome sicca 440 | 840
active Crohn's disease 436 | 918
acute myeloid leukemia 427 | 780
gastric carcinoma 426 | 832
esophageal adenocarcinoma 409 | 737
Atopic dermatitis 408 | 944
primary Sjogren syndrome 398 | 789
Duchenne muscular dystrophy 393 | 602
progressive supranuclear palsy 369 | 674
Alzheimer's disease 351 | 644
tuberculosis and treatment for 6 months 349 | 686
aldosterone-producing adenoma 343 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 319 | 499
Down syndrome 315 | 548
Intellectual disability 305 | 573
pancreatic carcinoma 298 | 567
Obesity 271 | 616
hepatocellular carcinoma 265 | 532
IGA Glomerulonephritis 262 | 454
Amyotrophic Lateral Sclerosis 258 | 431
fibroadenoma 257 | 557
Prostatic Neoplasms 253 | 471
Neurodegenerative disease 237 | 383
mucosa-associated lymphoid tissue lymphoma 237 | 480
gastric cancer 225 | 430
hereditary spastic paraplegia 221 | 313
Schizophrenia 220 | 501
Mammary Neoplasms 217 | 410
Endometriosis 208 | 535
Multiple Sclerosis 202 | 498
active ulcerative colitis 197 | 477
chronic rhinosinusitis 192 | 512
Kidney disease 190 | 396
Parkinson's disease 183 | 364
non-small cell lung carcinoma 181 | 413
Polycystic Ovary Syndrome 177 | 332
inflammatory breast cancer 176 | 404
nephrosclerosis 171 | 329
Stomach Neoplasms 169 | 282
sarcoidosis 169 | 358
interstitial lung disease 165 | 291
glioblastoma multiforme 161 | 347
Vascular disease 160 | 281

Tissue

Digestive Tract 8,032 | 18,473
Nervous System 8,019 | 18,561
Urinary Tract 8,017 | 18,444
Liver and Pancreas 8,016 | 18,136
Female tissues 8,014 | 18,647
Male tissues 8,008 | 17,969
Endocrine System 8,005 | 18,512
Blood and immune system 7,997 | 17,995
Cardiovascular System 7,983 | 17,958
Respiratory system 7,944 | 17,484
Skin and soft tissues 7,895 | 18,115

Target Family

Non-IDG 4,694 | 11,971
Enzyme 2,137 | 4,146
Transcription Factor 412 | 1,400
Kinase 389 | 634
Transporter 137 | 473
Epigenetic 110 | 242
Ion Channel 90 | 341
GPCR 35 | 406
TF/Epigenetic 13 | 38
Nuclear Receptor 9 | 48
oGPCR 6 | 421

HPM Tissue

Adult Rectum 8,032 | 8,032
Adult Testis 10,843 | 10,843
Adult Ovary 10,201 | 10,201
Adult Retina 10,124 | 10,124
CD8 Cells 9,849 | 9,849
Fetal Heart 9,239 | 9,239
Adult Pancreas 9,175 | 9,175
Fetal Ovary 9,127 | 9,127
Adult Liver 9,122 | 9,122
B Cells 9,091 | 9,091
Adult Frontal Cortex 9,054 | 9,054
Adult Prostate 8,963 | 8,963
Fetal Gut 8,648 | 8,648
NK Cells 8,481 | 8,481
Adult Adrenal 8,479 | 8,479
Fetal Liver 8,410 | 8,410
Fetal Testis 7,961 | 7,961
Adult Colon 7,921 | 7,921
Fetal Brain 7,871 | 7,871
CD4 Cells 7,779 | 7,779
Adult Gallbladder 7,619 | 7,619
Adult Urinary Bladder 7,601 | 7,601
Adult Spinal Cord 7,599 | 7,599
Monocytes 7,427 | 7,427
Adult Kidney 6,728 | 6,728
Adult Lung 6,669 | 6,669
Adult Heart 6,510 | 6,510
Platelets 6,133 | 6,133
Placenta 6,087 | 6,087
Adult Esophagus 4,939 | 4,939

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Syntaxin-1B STX1B Tbio Non-IDG -1.74488 52.6 27
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.31593 2169.0 108
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Zinc finger protein 485 ZNF485 Tdark Transcription Factor 0.00000 48
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
ATP synthase F(0) complex subunit C3, mitochondrial ATP5G3 Tdark Enzyme -1.10871 11.9 27
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193