Development Level

Tbio 6,413 | 10,625
Tdark 2,330 | 7,003
Tchem 1,151 | 1,890
Tclin 306 | 602

Collection

Kinase: IDG Consortium (Targets) 74 | 125
Ion Channel: IDG Consortium (Targets) 36 | 102
Kinase: IDG Consortium (Complete/Control) 25 | 37
GPCR: IDG Consortium (Targets) 19 | 128
GPCR: IDG Consortium (Complete/Control) 5 | 24

IMPC Phenotype

preweaning lethality, complete... 463 | 633
preweaning lethality, incomple... 167 | 260
abnormal behavior 149 | 226
embryonic lethality prior to t... 143 | 187
decreased lean body mass 133 | 195
decreased total body fat amoun... 133 | 186
embryonic lethality prior to o... 121 | 148
decreased body weight 120 | 174
decreased bone mineral content 101 | 157
increased circulating alkaline... 89 | 119
abnormal embryo size 82 | 112
decreased body length 82 | 108
decreased grip strength 80 | 123
abnormal bone structure 78 | 131
decreased bone mineral density 78 | 126
increased or absent threshold ... 74 | 128
decreased circulating glucose ... 73 | 121
hyperactivity 72 | 108
abnormal retina morphology 67 | 100
increased lean body mass 67 | 107
increased mean corpuscular hem... 63 | 93
increased bone mineral content 60 | 92
decreased circulating choleste... 55 | 85
hypoactivity 55 | 89
decreased circulating HDL chol... 53 | 77
increased mean corpuscular vol... 53 | 91
enlarged heart 51 | 111
short tibia 50 | 82
decreased circulating serum al... 49 | 79
abnormal lens morphology 48 | 73
decreased circulating insulin ... 48 | 75
increased fasted circulating g... 48 | 68
increased grip strength 48 | 83
decreased circulating triglyce... 46 | 83
decreased mean corpuscular vol... 43 | 50
prenatal lethality prior to he... 43 | 64
abnormal retinal pigmentation 42 | 61
male infertility 42 | 62
increased circulating HDL chol... 41 | 63
abnormal sleep behavior 40 | 63
decreased lumbar vertebrae num... 37 | 62
increased circulating choleste... 37 | 53
increased circulating sodium l... 37 | 71
decreased leukocyte cell numbe... 35 | 54
decreased rib number 35 | 59
impaired glucose tolerance 35 | 52
abnormal bone mineralization 34 | 55
increased bone mineral density 34 | 52
increased total body fat amoun... 34 | 57
thrombocytopenia 34 | 46
abnormal coat-hair pigmentatio... 33 | 54
decreased caudal vertebrae num... 33 | 49
increased hemoglobin content 33 | 45
abnormal gait 32 | 51
decreased fasted circulating g... 32 | 49
increased sacral vertebrae num... 31 | 62
abnormal behavioral response t... 30 | 52
decreased prepulse inhibition 30 | 52
improved glucose tolerance 30 | 56
decreased erythrocyte cell num... 29 | 43
decreased hemoglobin content 29 | 53
increased blood urea nitrogen ... 29 | 44
increased exploration in new e... 29 | 56
decreased circulating alanine ... 28 | 53
decreased circulating total pr... 28 | 41
decreased eosinophil cell numb... 28 | 41
increased body weight 28 | 42
cardiovascular system phenotyp... 27 | 35
decreased heart weight 27 | 44
increased circulating chloride... 27 | 43
increased hematocrit 27 | 36
abnormal seminal vesicle morph... 26 | 47
decreased circulating LDL chol... 26 | 37
increased leukocyte cell numbe... 26 | 37
abnormal neural tube closure 25 | 37
decreased circulating alkaline... 25 | 41
decreased startle reflex 25 | 48
increased heart weight 24 | 37
abnormal cranium morphology 23 | 32
decreased circulating free fat... 23 | 39
decreased mean corpuscular hem... 23 | 34
increased startle reflex 23 | 38
abnormal heart morphology 22 | 51
decreased circulating calcium ... 22 | 33
embryonic growth retardation 22 | 28
increased rib number 22 | 41
abnormal eye morphology 21 | 38
abnormal spleen morphology 21 | 36
decreased circulating fructosa... 21 | 31
increased erythrocyte cell num... 21 | 26
small testis 21 | 37
tremors 21 | 34
decreased blood urea nitrogen ... 20 | 31
decreased neutrophil cell numb... 20 | 37
increased circulating calcium ... 20 | 32
increased circulating phosphat... 20 | 24
increased circulating potassiu... 20 | 31
limb grasping 20 | 35
decreased T cell number 19 | 31
decreased circulating aspartat... 19 | 27

Disease

ovarian cancer 5,627 | 8,491
osteosarcoma 4,754 | 7,933
medulloblastoma, large-cell 3,753 | 6,234
psoriasis 3,689 | 6,685
glioblastoma 3,445 | 5,572
lung cancer 2,894 | 4,473
atypical teratoid / rhabdoid tumor 2,659 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 2,033 | 3,289
malignant mesothelioma 1,960 | 3,163
Breast cancer 1,921 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 1,838 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 1,815 | 2,956
primitive neuroectodermal tumor 1,812 | 3,031
invasive ductal carcinoma 1,800 | 2,950
pilocytic astrocytoma 1,780 | 3,086
oligodendroglioma 1,758 | 2,849
pediatric high grade glioma 1,660 | 2,712
non-small cell lung cancer 1,640 | 2,798
ependymoma 1,638 | 2,514
lung carcinoma 1,545 | 2,844
lung adenocarcinoma 1,521 | 2,714
subependymal giant cell astrocytoma 1,411 | 2,287
pancreatic cancer 1,400 | 2,300
Cancer 1,396 | 2,346
Carcinoma 1,396 | 2,147
astrocytic glioma 1,378 | 2,241
group 3 medulloblastoma 1,345 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 1,266 | 1,795
Pick disease 1,261 | 1,893
group 4 medulloblastoma 1,206 | 1,875
adult high grade glioma 1,200 | 2,148
ulcerative colitis 1,176 | 2,087
interstitial cystitis 1,112 | 2,299
Multiple myeloma 1,092 | 1,327
pituitary cancer 1,086 | 1,972
ductal carcinoma in situ 1,024 | 1,745
astrocytoma 1,023 | 1,493
breast carcinoma 990 | 1,614
cystic fibrosis 938 | 1,670
tuberculosis 934 | 1,563
diabetes mellitus 929 | 1,663
colon cancer 912 | 1,475
sonic hedgehog group medulloblastoma 904 | 1,482
medulloblastoma 894 | 1,524
primary pancreatic ductal adenocarcinoma 871 | 1,271
acute quadriplegic myopathy 866 | 1,157
adrenocortical carcinoma 859 | 1,427
juvenile dermatomyositis 854 | 1,189
posterior fossa group A ependymoma 838 | 1,511
posterior fossa group B ependymoma 803 | 1,530
dermatomyositis 753 | 966
Rheumatoid Arthritis 701 | 1,170
atypical teratoid/rhabdoid tumor 650 | 1,095
Waldenstrons macroglobulinemia 621 | 764
spina bifida 611 | 1,064
nasopharyngeal carcinoma 561 | 1,056
non primary Sjogren syndrome sicca 528 | 840
cutaneous lupus erythematosus 526 | 1,056
acute myeloid leukemia 521 | 785
active Crohn's disease 518 | 918
gastric carcinoma 513 | 832
Atopic dermatitis 500 | 944
primary Sjogren syndrome 458 | 788
Duchenne muscular dystrophy 451 | 602
esophageal adenocarcinoma 451 | 737
tuberculosis and treatment for 6 months 448 | 686
progressive supranuclear palsy 447 | 674
aldosterone-producing adenoma 428 | 664
Intellectual disability 413 | 573
Alzheimer's disease 401 | 644
autosomal dominant Emery-Dreifuss muscular dystrophy 370 | 499
Down syndrome 364 | 548
pancreatic carcinoma 357 | 567
hepatocellular carcinoma 336 | 550
Obesity 328 | 616
fibroadenoma 322 | 557
Amyotrophic Lateral Sclerosis 317 | 432
Neurodegenerative disease 306 | 383
IGA Glomerulonephritis 303 | 454
Prostatic Neoplasms 289 | 471
Endometriosis 272 | 535
Schizophrenia 271 | 503
gastric cancer 271 | 436
mucosa-associated lymphoid tissue lymphoma 268 | 480
hereditary spastic paraplegia 264 | 313
chronic rhinosinusitis 258 | 512
Multiple Sclerosis 247 | 498
Mammary Neoplasms 244 | 410
active ulcerative colitis 238 | 477
Parkinson's disease 225 | 364
inflammatory breast cancer 222 | 404
non-small cell lung carcinoma 212 | 413
Polycystic Ovary Syndrome 210 | 334
Kidney disease 204 | 397
interstitial lung disease 201 | 292
sarcoidosis 199 | 368
Epilepsy 196 | 346
glioblastoma multiforme 196 | 347
tuberculosis and treatment for 3 months 187 | 327
Crohn's disease 183 | 304

Tissue

Female tissues 10,200 | 18,646
Male tissues 10,159 | 17,968
Nervous System 10,157 | 18,560
Endocrine System 10,137 | 18,511
Digestive Tract 10,129 | 18,472
Blood and immune system 10,123 | 17,994
Urinary Tract 10,106 | 18,443
Liver and Pancreas 10,103 | 18,135
Cardiovascular System 10,076 | 17,957
Respiratory system 9,978 | 17,483
Skin and soft tissues 9,968 | 18,114

Target Family

Non-IDG 5,966 | 11,969
Enzyme 2,557 | 4,146
Transcription Factor 633 | 1,400
Kinase 463 | 634
Transporter 194 | 473
Epigenetic 162 | 242
Ion Channel 111 | 341
GPCR 58 | 408
Nuclear Receptor 24 | 48
TF/Epigenetic 19 | 38
oGPCR 13 | 421

HPM Tissue

Adult Ovary 10,200 | 10,200
Adult Testis 10,842 | 10,842
Adult Retina 10,123 | 10,123
CD8 Cells 9,848 | 9,848
Fetal Heart 9,238 | 9,238
Adult Pancreas 9,174 | 9,174
Fetal Ovary 9,126 | 9,126
Adult Liver 9,121 | 9,121
B Cells 9,090 | 9,090
Adult Frontal Cortex 9,053 | 9,053
Adult Prostate 8,962 | 8,962
Fetal Gut 8,647 | 8,647
NK Cells 8,480 | 8,480
Adult Adrenal 8,478 | 8,478
Fetal Liver 8,409 | 8,409
Adult Rectum 8,031 | 8,031
Fetal Testis 7,960 | 7,960
Adult Colon 7,920 | 7,920
Fetal Brain 7,870 | 7,870
CD4 Cells 7,778 | 7,778
Adult Gallbladder 7,618 | 7,618
Adult Urinary Bladder 7,600 | 7,600
Adult Spinal Cord 7,598 | 7,598
Monocytes 7,426 | 7,426
Adult Kidney 6,727 | 6,727
Adult Lung 6,668 | 6,668
Adult Heart 6,509 | 6,509
Platelets 6,132 | 6,132
Placenta 6,086 | 6,086
Adult Esophagus 4,938 | 4,938

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.50722 29.2 46
F-box/LRR-repeat protein 3 FBXL3 Tbio Non-IDG -0.94799 9.59 158
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
Zinc finger protein 215 ZNF215 Tdark Transcription Factor -0.47111 3.15 74
Epithelial membrane protein 3 EMP3 Tbio Non-IDG -1.64647 44.8 131
F-box/WD repeat-containing protein 2 FBXW2 Tbio Non-IDG -1.99707 87.2 90
Hydroxymethylglutaryl-CoA synthase, mitochondrial HMGCS2 Tbio Enzyme -1.69372 46.6 95
Phosphoglycerate mutase 2 PGAM2 Tbio Enzyme -1.54638 36.2 160
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
Splicing regulatory glutamine/lysine-rich protein 1 SREK1 Tdark Non-IDG -0.37946 3.77 39