Development Level
Tbio | 5,226 | 10,625 | |
Tdark | 1,431 | 7,003 | |
Tchem | 1,004 | 1,890 | |
Tclin | 260 | 602 |
Collection
Eligible Kinase Proteins | 66 | 134 | |
Eligible Ion Channel Proteins | 28 | 117 | |
Eligible non-olfactory GPCR Proteins | 13 | 145 |
IMPC Term
preweaning lethality, complete... | 375 | 633 | |
preweaning lethality, incomple... | 130 | 260 | |
embryonic lethality prior to t... | 113 | 187 | |
abnormal behavior | 109 | 226 | |
decreased lean body mass | 106 | 195 | |
decreased total body fat amoun... | 102 | 186 | |
embryonic lethality prior to o... | 102 | 148 | |
decreased body weight | 97 | 174 | |
decreased bone mineral content | 77 | 157 | |
abnormal bone structure | 70 | 131 | |
increased circulating alkaline... | 70 | 119 | |
increased or absent threshold ... | 68 | 128 | |
abnormal embryo size | 66 | 112 | |
decreased grip strength | 64 | 123 | |
decreased bone mineral density | 62 | 126 | |
decreased circulating glucose ... | 61 | 121 | |
decreased body length | 59 | 108 | |
abnormal retina morphology | 56 | 100 | |
increased mean corpuscular hem... | 53 | 93 | |
hyperactivity | 52 | 108 | |
increased lean body mass | 50 | 107 | |
hypoactivity | 47 | 89 | |
increased bone mineral content | 47 | 92 | |
abnormal lens morphology | 45 | 73 | |
decreased circulating choleste... | 45 | 85 | |
decreased circulating triglyce... | 45 | 83 | |
short tibia | 45 | 82 | |
enlarged heart | 43 | 111 | |
decreased circulating HDL chol... | 41 | 77 | |
decreased circulating insulin ... | 41 | 75 | |
decreased circulating serum al... | 39 | 79 | |
decreased mean corpuscular vol... | 39 | 50 | |
increased mean corpuscular vol... | 39 | 91 | |
increased grip strength | 38 | 83 | |
prenatal lethality prior to he... | 35 | 64 | |
increased fasted circulating g... | 34 | 68 | |
abnormal sleep behavior | 33 | 63 | |
increased circulating HDL chol... | 32 | 63 | |
decreased lumbar vertebrae num... | 31 | 62 | |
increased circulating choleste... | 30 | 53 | |
increased circulating sodium l... | 30 | 71 | |
abnormal bone mineralization | 29 | 55 | |
male infertility | 29 | 62 | |
decreased leukocyte cell numbe... | 28 | 54 | |
impaired glucose tolerance | 28 | 52 | |
abnormal retinal pigmentation | 27 | 61 | |
increased body weight | 27 | 42 | |
increased exploration in new e... | 27 | 56 | |
decreased fasted circulating g... | 26 | 49 | |
increased bone mineral density | 26 | 52 | |
abnormal coat/hair pigmentatio... | 25 | 54 | |
decreased circulating alanine ... | 25 | 53 | |
increased hemoglobin content | 25 | 45 | |
increased sacral vertebrae num... | 25 | 62 | |
increased total body fat amoun... | 25 | 57 | |
thrombocytopenia | 25 | 46 | |
decreased hemoglobin content | 24 | 53 | |
decreased rib number | 24 | 59 | |
increased blood urea nitrogen ... | 24 | 44 | |
abnormal gait | 23 | 51 | |
decreased heart weight | 23 | 44 | |
abnormal seminal vesicle morph... | 22 | 47 | |
cardiovascular system phenotyp... | 22 | 35 | |
decreased caudal vertebrae num... | 22 | 49 | |
decreased circulating alkaline... | 22 | 41 | |
decreased prepulse inhibition | 22 | 52 | |
improved glucose tolerance | 22 | 56 | |
abnormal neural tube closure | 21 | 37 | |
decreased eosinophil cell numb... | 21 | 41 | |
decreased mean corpuscular hem... | 21 | 34 | |
decreased startle reflex | 21 | 48 | |
abnormal behavioral response t... | 20 | 52 | |
decreased circulating calcium ... | 20 | 33 | |
decreased circulating free fat... | 20 | 39 | |
decreased circulating total pr... | 20 | 41 | |
decreased erythrocyte cell num... | 20 | 43 | |
increased circulating chloride... | 20 | 43 | |
increased hematocrit | 20 | 36 | |
small testis | 20 | 37 | |
abnormal heart morphology | 19 | 51 | |
decreased circulating LDL chol... | 19 | 37 | |
increased leukocyte cell numbe... | 19 | 37 | |
increased startle reflex | 19 | 38 | |
abnormal cranium morphology | 18 | 32 | |
abnormal eye morphology | 18 | 38 | |
increased circulating phosphat... | 18 | 24 | |
increased circulating potassiu... | 18 | 31 | |
increased heart weight | 18 | 37 | |
abnormal testis morphology | 17 | 30 | |
decreased circulating creatini... | 17 | 31 | |
decreased circulating fructosa... | 17 | 31 | |
decreased threshold for audito... | 17 | 32 | |
increased circulating calcium ... | 17 | 32 | |
decreased circulating aspartat... | 16 | 27 | |
decreased circulating chloride... | 16 | 32 | |
decreased neutrophil cell numb... | 16 | 37 | |
increased rib number | 16 | 41 | |
tremors | 16 | 34 | |
abnormal spleen morphology | 15 | 36 | |
decreased circulating iron lev... | 15 | 25 |
Disease
Tissue
Digestive Tract | 7,921 | 18,473 | |
Female tissues | 7,899 | 18,647 | |
Nervous System | 7,899 | 18,561 | |
Urinary Tract | 7,895 | 18,444 | |
Blood and immune system | 7,894 | 17,995 | |
Liver and Pancreas | 7,894 | 18,136 | |
Endocrine System | 7,886 | 18,512 | |
Male tissues | 7,886 | 17,969 | |
Cardiovascular System | 7,871 | 17,958 | |
Respiratory system | 7,825 | 17,484 | |
Skin and soft tissues | 7,781 | 18,115 |
Target Family
Non-IDG | 4,704 | 11,969 | |
Enzyme | 2,200 | 4,146 | |
Kinase | 390 | 634 | |
Transcription Factor | 228 | 1,400 | |
Transporter | 159 | 473 | |
Epigenetic | 91 | 242 | |
Ion Channel | 84 | 341 | |
GPCR | 36 | 408 | |
TF/Epigenetic | 13 | 38 | |
Nuclear Receptor | 8 | 48 | |
oGPCR | 8 | 421 |
HPM Tissue
Adult Colon | 7,921 | 7,921 | |
Adult Testis | 10,843 | 10,843 | |
Adult Ovary | 10,201 | 10,201 | |
Adult Retina | 10,124 | 10,124 | |
CD8 Cells | 9,849 | 9,849 | |
Fetal Heart | 9,239 | 9,239 | |
Adult Pancreas | 9,175 | 9,175 | |
Fetal Ovary | 9,127 | 9,127 | |
Adult Liver | 9,122 | 9,122 | |
B Cells | 9,091 | 9,091 | |
Adult Frontal Cortex | 9,054 | 9,054 | |
Adult Prostate | 8,963 | 8,963 | |
Fetal Gut | 8,648 | 8,648 | |
NK Cells | 8,481 | 8,481 | |
Adult Adrenal | 8,479 | 8,479 | |
Fetal Liver | 8,410 | 8,410 | |
Adult Rectum | 8,032 | 8,032 | |
Fetal Testis | 7,961 | 7,961 | |
Fetal Brain | 7,871 | 7,871 | |
CD4 Cells | 7,779 | 7,779 | |
Adult Gallbladder | 7,619 | 7,619 | |
Adult Urinary Bladder | 7,601 | 7,601 | |
Adult Spinal Cord | 7,599 | 7,599 | |
Monocytes | 7,427 | 7,427 | |
Adult Kidney | 6,728 | 6,728 | |
Adult Lung | 6,669 | 6,669 | |
Adult Heart | 6,510 | 6,510 | |
Platelets | 6,133 | 6,133 | |
Placenta | 6,087 | 6,087 | |
Adult Esophagus | 4,939 | 4,939 |
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