Development Level

Tbio 5,849 | 11,651
Tdark 1,566 | 6,593
Tchem 773 | 1,388
Tclin 287 | 612

Collection

RFA-RM-18-021 86 | 328
Kinase: IDG Consortium (Target... 52 | 125
Ion Channel: IDG Consortium (T... 26 | 99
Kinase: IDG Consortium (Comple... 22 | 37
GPCR: IDG Consortium (Targets) 8 | 126
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, complete... 640 | 979
preweaning lethality, incomple... 271 | 499
embryonic lethality prior to t... 177 | 278
embryonic lethality prior to o... 170 | 239
abnormal behavior 142 | 298
abnormal embryo size 127 | 220
decreased total body fat amoun... 108 | 207
abnormal bone structure 99 | 187
decreased body weight 89 | 161
enlarged heart 86 | 210
increased lean body mass 82 | 172
decreased vertical activity 81 | 208
decreased bone mineral content 78 | 151
hypoactivity 75 | 132
embryonic growth retardation 68 | 106
decreased bone mineral density 67 | 126
decreased circulating glucose ... 67 | 126
increased circulating alkaline... 66 | 122
hyperactivity 65 | 148
abnormal heart morphology 64 | 162
increased total body fat amoun... 64 | 134
decreased lean body mass 62 | 135
decreased grip strength 58 | 116
increased startle reflex 58 | 112
male infertility 57 | 123
short tibia 57 | 97
increased bone mineral content 54 | 108
cataract 52 | 92
increased mean corpuscular hem... 52 | 96
prenatal lethality prior to he... 52 | 87
abnormal seminal vesicle morph... 51 | 114
decreased body length 49 | 101
increased or absent threshold ... 49 | 101
abnormal lens morphology 48 | 81
decreased circulating choleste... 47 | 93
increased mean corpuscular vol... 46 | 92
decreased circulating serum al... 45 | 82
decreased mean corpuscular vol... 45 | 79
increased fasted circulating g... 45 | 76
decreased prepulse inhibition 43 | 82
increased bone mineral density 41 | 72
abnormal retina morphology 40 | 71
increased circulating choleste... 40 | 66
decreased startle reflex 38 | 75
impaired glucose tolerance 38 | 75
improved glucose tolerance 38 | 79
increased circulating HDL chol... 38 | 80
decreased circulating HDL chol... 37 | 68
decreased circulating triglyce... 36 | 79
decreased leukocyte cell numbe... 36 | 73
decreased lymphocyte cell numb... 36 | 83
abnormal gait 35 | 69
decreased circulating insulin ... 35 | 76
decreased fasted circulating g... 35 | 65
increased heart weight 35 | 62
abnormal behavioral response t... 34 | 66
abnormal eye morphology 34 | 68
decreased erythrocyte cell num... 34 | 62
abnormal sleep behavior 33 | 70
abnormal coat-hair pigmentatio... 32 | 64
abnormal kidney morphology 32 | 65
decreased caudal vertebrae num... 32 | 53
decreased circulating total pr... 32 | 49
edema 32 | 59
decreased circulating alkaline... 31 | 46
decreased hemoglobin content 31 | 68
small superior vagus ganglion 30 | 74
increased mean platelet volume 29 | 45
abnormal skin morphology 28 | 50
decreased mean corpuscular hem... 28 | 50
increased blood urea nitrogen ... 28 | 48
increased circulating sodium l... 27 | 71
increased hematocrit 27 | 46
small testis 27 | 58
thrombocytopenia 27 | 56
decreased circulating alanine ... 26 | 47
increased monocyte cell number 26 | 63
increased neutrophil cell numb... 26 | 46
decreased circulating calcium ... 25 | 36
increased erythrocyte cell num... 25 | 39
increased leukocyte cell numbe... 25 | 47
decreased neutrophil cell numb... 24 | 42
decreased red blood cell distr... 24 | 41
limb grasping 23 | 41
abnormal testis morphology 22 | 43
decreased circulating LDL chol... 22 | 38
decreased circulating aspartat... 22 | 34
decreased hematocrit 22 | 46
hydrometra 22 | 53
increased circulating triglyce... 22 | 42
increased grip strength 22 | 41
tremors 22 | 39
abnormal neural tube closure 21 | 46
decreased circulating fructosa... 21 | 30
decreased mean corpuscular hem... 21 | 31
increased hemoglobin content 21 | 45
abnormal bone mineralization 20 | 38
cardiovascular system phenotyp... 20 | 36
increased circulating chloride... 20 | 41
prolonged QT interval 20 | 38

Disease

Carcinoma 5,484 | 11,493
ovarian cancer 4,852 | 8,520
osteosarcoma 3,985 | 7,950
medulloblastoma, large-cell 3,140 | 6,241
psoriasis 3,115 | 6,694
glioblastoma 3,038 | 5,792
lung cancer 2,606 | 4,740
atypical teratoid / rhabdoid tumor 2,587 | 5,112
ependymoma 2,335 | 4,679
group 3 medulloblastoma 2,016 | 4,104
Breast cancer 1,873 | 3,578
adult high grade glioma 1,829 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 1,737 | 3,291
malignant mesothelioma 1,681 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 1,564 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 1,546 | 2,955
invasive ductal carcinoma 1,528 | 2,951
Astrocytoma, Pilocytic 1,520 | 3,081
Kidney cancer 1,480 | 2,613
primitive neuroectodermal tumor 1,472 | 3,035
oligodendroglioma 1,468 | 2,850
non-small cell lung cancer 1,424 | 2,890
astrocytic glioma 1,362 | 2,597
lung carcinoma 1,356 | 2,843
lung adenocarcinoma 1,307 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 1,283 | 1,962
pancreatic cancer 1,262 | 2,398
Cancer 1,242 | 2,499
subependymal giant cell astrocytoma 1,224 | 2,287
Pick disease 1,108 | 1,894
Multiple myeloma 1,029 | 1,332
tuberculosis 990 | 2,010
group 4 medulloblastoma 972 | 1,855
interstitial cystitis 945 | 2,312
pituitary cancer 902 | 1,972
Autosomal recessive predisposition 888 | 1,442
diabetes mellitus 888 | 1,728
ulcerative colitis 867 | 1,819
ductal carcinoma in situ 852 | 1,745
breast carcinoma 839 | 1,638
cystic fibrosis 804 | 1,696
acute quadriplegic myopathy 780 | 1,158
colon cancer 774 | 1,478
adrenocortical carcinoma 752 | 1,428
juvenile dermatomyositis 750 | 1,187
astrocytoma 704 | 1,146
dermatomyositis 689 | 966
primary pancreatic ductal adenocarcinoma 647 | 1,109
Rheumatoid arthritis 642 | 1,191
Intellectual disability 596 | 1,016
pediatric high grade glioma 590 | 1,064
Waldenstrons macroglobulinemia 588 | 765
Schizophrenia 587 | 1,160
spina bifida 517 | 1,074
Epilepsy 486 | 792
non primary Sjogren syndrome sicca 481 | 891
nasopharyngeal carcinoma 468 | 1,058
active Crohn's disease 458 | 922
cutaneous lupus erythematosus 455 | 1,057
acute myeloid leukemia 436 | 783
Liver Cirrhosis, Experimental 428 | 769
Atopic dermatitis 426 | 952
gastric carcinoma 417 | 807
Cognitive delay 411 | 608
Global developmental delay 411 | 608
Mental and motor retardation 411 | 608
Dull intelligence 397 | 645
Low intelligence 397 | 645
Mental Retardation 397 | 645
Mental deficiency 397 | 645
Poor school performance 397 | 645
esophageal adenocarcinoma 396 | 737
Duchenne muscular dystrophy 393 | 601
progressive supranuclear palsy 392 | 676
Seizures 385 | 596
Muscle hypotonia 384 | 571
primary Sjogren syndrome 383 | 735
Alzheimer's disease 380 | 658
aldosterone-producing adenoma 376 | 665
Liver cancer 374 | 604
active ulcerative colitis 362 | 764
medulloblastoma 362 | 720
Melanoma 355 | 711
autosomal dominant Emery-Dreifuss muscular dystrophy 332 | 510
Obesity 329 | 678
Short stature 320 | 531
pancreatic carcinoma 311 | 562
Bipolar Disorder 304 | 666
Down syndrome 298 | 499
Neurodegenerative disease 295 | 414
hepatocellular carcinoma 295 | 547
Prostatic Neoplasms 287 | 495
Amyotrophic lateral sclerosis 281 | 451
fibroadenoma 258 | 559
Skin cancer 252 | 469
Breast Neoplasms 244 | 445
tuberculosis and treatment for 6 months 243 | 409
gastric cancer 241 | 459
Small head 240 | 374
mucosa-associated lymphoid tissue lymphoma 239 | 484

Tissue

Endocrine System 8,364 | 18,159
Female tissues 8,255 | 17,400
Digestive Tract 8,224 | 17,369
Skin and soft tissues 8,210 | 17,230
Male tissues 8,186 | 17,142
Blood and immune system 8,141 | 16,909
Liver and Pancreas 8,112 | 16,750
Urinary Tract 8,091 | 16,678
Nervous System 8,082 | 16,725
Respiratory system 8,036 | 16,393
Cardiovascular System 7,774 | 15,192

Target Family

Non-IDG 4,936 | 12,091
Enzyme 2,297 | 4,145
Transcription Factor 409 | 1,400
Kinase 385 | 634
Transporter 181 | 473
Epigenetic 115 | 242
Ion Channel 93 | 344
GPCR 31 | 408
TF/Epigenetic 13 | 38
oGPCR 9 | 421
Nuclear Receptor 6 | 48

HPM Tissue

Adult Adrenal 8,475 | 8,475
Adult Testis 10,836 | 10,836
Adult Ovary 10,192 | 10,192
Adult Retina 10,115 | 10,115
CD8 Cells 9,840 | 9,840
Fetal Heart 9,228 | 9,228
Adult Pancreas 9,168 | 9,168
Fetal Ovary 9,118 | 9,118
Adult Liver 9,113 | 9,113
B Cells 9,086 | 9,086
Adult Frontal Cortex 9,048 | 9,048
Adult Prostate 8,952 | 8,952
Fetal Gut 8,640 | 8,640
NK Cells 8,475 | 8,475
Fetal Liver 8,402 | 8,402
Adult Rectum 8,022 | 8,022
Fetal Testis 7,955 | 7,955
Adult Colon 7,915 | 7,915
Fetal Brain 7,866 | 7,866
CD4 Cells 7,773 | 7,773
Adult Gallbladder 7,612 | 7,612
Adult Spinal Cord 7,594 | 7,594
Adult Urinary Bladder 7,592 | 7,592
Monocytes 7,422 | 7,422
Adult Kidney 6,723 | 6,723
Adult Lung 6,663 | 6,663
Adult Heart 6,506 | 6,506
Platelets 6,131 | 6,131
Placenta 6,083 | 6,083
Adult Esophagus 4,936 | 4,936

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 215 ZNF215 Tdark Transcription Factor -0.51747 3.15 91
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
Paralemmin-3 PALM3 Tbio Non-IDG -0.66901 5.71 76
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Serine/arginine-rich splicing factor 12 SRSF12 Tbio Non-IDG -0.09691 1.17 22
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Sphingomyelin phosphodiesterase 4 SMPD4 Tbio Enzyme -0.89678 7.05 66