Development Level
Tbio | 9,833 | 11,445 | |
Tdark | 3,714 | 6,588 | |
Tchem | 1,379 | 1,598 | |
Tclin | 474 | 613 |
Collection
RFA-RM-18-021 | 233 | 328 | |
Kinase: IDG Consortium (Target... | 106 | 125 | |
Ion Channel: IDG Consortium (T... | 69 | 99 | |
GPCR: IDG Consortium (Targets) | 61 | 126 | |
Kinase: IDG Consortium (Comple... | 31 | 37 | |
GPCR: IDG Consortium (Complete... | 21 | 25 |
IMPC Phenotype
preweaning lethality, complete... | 936 | 979 | |
preweaning lethality, incomple... | 456 | 499 | |
embryonic lethality prior to t... | 268 | 278 | |
abnormal behavior | 266 | 298 | |
embryonic lethality prior to o... | 236 | 239 | |
abnormal embryo size | 208 | 220 | |
decreased total body fat amoun... | 187 | 207 | |
enlarged heart | 185 | 210 | |
decreased vertical activity | 164 | 208 | |
abnormal bone structure | 160 | 187 | |
increased lean body mass | 154 | 172 | |
abnormal heart morphology | 147 | 162 | |
decreased body weight | 144 | 161 | |
decreased bone mineral content | 129 | 151 | |
hyperactivity | 124 | 148 | |
decreased lean body mass | 119 | 135 | |
decreased circulating glucose ... | 114 | 126 | |
increased total body fat amoun... | 113 | 134 | |
decreased bone mineral density | 110 | 126 | |
hypoactivity | 110 | 132 | |
increased circulating alkaline... | 110 | 122 | |
embryonic growth retardation | 101 | 106 | |
decreased grip strength | 97 | 116 | |
male infertility | 97 | 123 | |
abnormal seminal vesicle morph... | 96 | 114 | |
increased startle reflex | 96 | 112 | |
increased bone mineral content | 94 | 108 | |
decreased body length | 93 | 101 | |
short tibia | 91 | 97 | |
increased or absent threshold ... | 90 | 101 | |
decreased circulating choleste... | 86 | 93 | |
increased mean corpuscular hem... | 86 | 96 | |
increased mean corpuscular vol... | 86 | 92 | |
prenatal lethality prior to he... | 84 | 87 | |
cataract | 83 | 92 | |
decreased lymphocyte cell numb... | 77 | 83 | |
abnormal lens morphology | 75 | 81 | |
decreased circulating serum al... | 75 | 82 | |
decreased prepulse inhibition | 70 | 82 | |
decreased mean corpuscular vol... | 69 | 79 | |
increased bone mineral density | 68 | 72 | |
increased fasted circulating g... | 68 | 76 | |
small superior vagus ganglion | 68 | 74 | |
decreased circulating triglyce... | 67 | 79 | |
decreased leukocyte cell numbe... | 67 | 73 | |
increased circulating HDL chol... | 67 | 80 | |
impaired glucose tolerance | 65 | 75 | |
abnormal eye morphology | 64 | 68 | |
abnormal retina morphology | 64 | 71 | |
decreased circulating HDL chol... | 64 | 68 | |
decreased circulating insulin ... | 64 | 76 | |
decreased startle reflex | 64 | 75 | |
improved glucose tolerance | 64 | 79 | |
abnormal sleep behavior | 61 | 70 | |
increased circulating sodium l... | 61 | 71 | |
abnormal coat-hair pigmentatio... | 59 | 64 | |
decreased fasted circulating g... | 59 | 65 | |
abnormal behavioral response t... | 58 | 66 | |
decreased erythrocyte cell num... | 58 | 62 | |
increased monocyte cell number | 58 | 63 | |
abnormal kidney morphology | 57 | 65 | |
decreased hemoglobin content | 57 | 68 | |
abnormal gait | 56 | 69 | |
edema | 56 | 59 | |
increased circulating choleste... | 55 | 66 | |
increased heart weight | 54 | 62 | |
small testis | 52 | 58 | |
abnormal spleen morphology | 51 | 55 | |
decreased caudal vertebrae num... | 50 | 53 | |
thrombocytopenia | 49 | 56 | |
decreased circulating total pr... | 48 | 49 | |
hydrometra | 48 | 53 | |
female infertility | 47 | 60 | |
abnormal skin morphology | 46 | 50 | |
decreased mean corpuscular hem... | 46 | 50 | |
decreased blood urea nitrogen ... | 45 | 51 | |
abnormal neural tube closure | 44 | 46 | |
decreased circulating alanine ... | 43 | 47 | |
increased neutrophil cell numb... | 43 | 46 | |
decreased circulating alkaline... | 42 | 46 | |
increased hematocrit | 42 | 46 | |
decreased hematocrit | 41 | 46 | |
increased blood urea nitrogen ... | 41 | 48 | |
increased leukocyte cell numbe... | 41 | 47 | |
increased mean platelet volume | 39 | 45 | |
abnormal testis morphology | 38 | 43 | |
enlarged spleen | 38 | 41 | |
increased hemoglobin content | 38 | 45 | |
decreased circulating LDL chol... | 37 | 38 | |
decreased neutrophil cell numb... | 37 | 42 | |
decreased red blood cell distr... | 36 | 41 | |
increased erythrocyte cell num... | 36 | 39 | |
abnormal cranium morphology | 35 | 36 | |
increased circulating chloride... | 35 | 41 | |
increased circulating triglyce... | 35 | 42 | |
tremors | 35 | 39 | |
abnormal bone mineralization | 34 | 38 | |
increased grip strength | 34 | 41 | |
decreased circulating creatini... | 33 | 39 | |
pallor | 33 | 34 |
Disease
Tissue
Blood and immune system | 15,400 | 16,909 | |
Digestive Tract | 15,352 | 17,369 | |
Endocrine System | 15,330 | 18,159 | |
Female tissues | 15,314 | 17,400 | |
Skin and soft tissues | 15,296 | 17,230 | |
Male tissues | 15,207 | 17,142 | |
Urinary Tract | 15,156 | 16,678 | |
Liver and Pancreas | 15,147 | 16,750 | |
Respiratory system | 15,068 | 16,393 | |
Nervous System | 14,970 | 16,725 | |
Cardiovascular System | 14,361 | 15,192 |
Target Family
Non-IDG | 8,970 | 12,091 | |
Enzyme | 3,590 | 4,145 | |
Transcription Factor | 1,130 | 1,400 | |
Kinase | 574 | 634 | |
Transporter | 360 | 473 | |
GPCR | 244 | 408 | |
Epigenetic | 230 | 242 | |
Ion Channel | 220 | 344 | |
Nuclear Receptor | 37 | 48 | |
TF/Epigenetic | 33 | 38 | |
oGPCR | 12 | 421 |
HPA RNA Tissue
tonsil | 15,400 | 15,400 | |
testis | 17,936 | 17,936 | |
cerebral cortex | 16,630 | 16,630 | |
prostate | 16,460 | 16,460 | |
endometrium | 16,349 | 16,349 | |
gallbladder | 16,333 | 16,333 | |
lung | 16,312 | 16,312 | |
appendix | 16,247 | 16,247 | |
fallopian tube | 16,245 | 16,245 | |
skin | 16,206 | 16,206 | |
small intestine | 16,154 | 16,154 | |
stomach | 16,099 | 16,099 | |
breast | 16,063 | 16,063 | |
duodenum | 15,975 | 15,975 | |
spleen | 15,972 | 15,972 | |
adrenal gland | 15,963 | 15,963 | |
colon | 15,959 | 15,959 | |
thyroid gland | 15,959 | 15,959 | |
placenta | 15,937 | 15,937 | |
seminal vesicle | 15,918 | 15,918 | |
kidney | 15,917 | 15,917 | |
esophagus | 15,898 | 15,898 | |
cervix, uterine | 15,871 | 15,871 | |
epididymis | 15,863 | 15,863 | |
smooth muscle | 15,857 | 15,857 | |
adipose tissue | 15,837 | 15,837 | |
lymph node | 15,833 | 15,833 | |
urinary bladder | 15,814 | 15,814 | |
rectum | 15,705 | 15,705 | |
ovary | 15,408 | 15,408 | |
salivary gland | 14,981 | 14,981 | |
heart muscle | 14,972 | 14,972 | |
parathyroid gland | 14,769 | 14,769 | |
liver | 14,587 | 14,587 | |
bone marrow | 14,571 | 14,571 | |
pancreas | 14,070 | 14,070 | |
skeletal muscle | 14,011 | 14,011 |
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