Development Level

Tbio 9,814 | 11,178
Tdark 3,839 | 6,569
Tchem 1,690 | 1,885
Tclin 514 | 612

Collection

Kinase: IDG Consortium (Target... 110 | 125
Ion Channel: IDG Consortium (T... 71 | 99
GPCR: IDG Consortium (Targets) 67 | 126
Kinase: IDG Consortium (Comple... 33 | 37
GPCR: IDG Consortium (Complete... 21 | 25

IMPC Phenotype

preweaning lethality, complete... 944 | 979
preweaning lethality, incomple... 462 | 499
abnormal behavior 277 | 298
embryonic lethality prior to t... 273 | 278
embryonic lethality prior to o... 237 | 239
abnormal embryo size 210 | 220
decreased total body fat amoun... 192 | 207
enlarged heart 180 | 210
decreased vertical activity 169 | 208
abnormal bone structure 167 | 187
increased lean body mass 160 | 172
decreased body weight 148 | 161
abnormal heart morphology 142 | 162
hyperactivity 138 | 148
decreased bone mineral content 136 | 151
decreased lean body mass 125 | 135
increased total body fat amoun... 122 | 134
hypoactivity 119 | 132
decreased circulating glucose ... 116 | 126
decreased bone mineral density 112 | 126
increased circulating alkaline... 111 | 122
decreased grip strength 105 | 116
male infertility 105 | 123
increased startle reflex 104 | 112
embryonic growth retardation 101 | 106
increased bone mineral content 99 | 108
abnormal seminal vesicle morph... 96 | 114
increased or absent threshold ... 94 | 101
decreased body length 93 | 101
increased mean corpuscular vol... 91 | 92
short tibia 91 | 97
increased mean corpuscular hem... 89 | 96
decreased circulating choleste... 87 | 93
cataract 85 | 92
prenatal lethality prior to he... 84 | 87
decreased lymphocyte cell numb... 78 | 83
abnormal lens morphology 76 | 81
decreased circulating serum al... 75 | 82
decreased prepulse inhibition 75 | 82
decreased circulating triglyce... 73 | 79
decreased mean corpuscular vol... 70 | 79
decreased leukocyte cell numbe... 69 | 73
decreased startle reflex 69 | 75
improved glucose tolerance 69 | 79
increased bone mineral density 69 | 72
increased circulating HDL chol... 69 | 80
abnormal retina morphology 67 | 71
impaired glucose tolerance 67 | 75
increased fasted circulating g... 67 | 76
increased circulating sodium l... 65 | 71
abnormal eye morphology 64 | 68
decreased circulating HDL chol... 64 | 68
decreased circulating insulin ... 64 | 76
small superior vagus ganglion 64 | 74
abnormal gait 63 | 69
abnormal sleep behavior 63 | 70
abnormal behavioral response t... 60 | 66
decreased hemoglobin content 59 | 68
abnormal coat-hair pigmentatio... 58 | 64
abnormal kidney morphology 58 | 65
decreased erythrocyte cell num... 58 | 62
decreased fasted circulating g... 58 | 65
increased circulating choleste... 58 | 66
increased monocyte cell number 58 | 63
increased heart weight 56 | 62
edema 55 | 59
small testis 54 | 58
decreased caudal vertebrae num... 53 | 53
thrombocytopenia 53 | 56
abnormal spleen morphology 50 | 55
female infertility 50 | 60
abnormal skin morphology 48 | 50
decreased circulating total pr... 47 | 49
decreased mean corpuscular hem... 46 | 50
abnormal neural tube closure 44 | 46
decreased blood urea nitrogen ... 44 | 51
decreased circulating alkaline... 44 | 46
hydrometra 44 | 53
decreased circulating alanine ... 43 | 47
increased hematocrit 43 | 46
increased neutrophil cell numb... 43 | 46
decreased hematocrit 42 | 46
increased blood urea nitrogen ... 42 | 48
increased hemoglobin content 42 | 45
increased leukocyte cell numbe... 41 | 47
increased mean platelet volume 40 | 45
abnormal testis morphology 39 | 43
decreased neutrophil cell numb... 39 | 42
decreased red blood cell distr... 39 | 41
enlarged spleen 39 | 41
increased circulating triglyce... 38 | 42
increased erythrocyte cell num... 38 | 39
limb grasping 38 | 41
decreased circulating LDL chol... 37 | 38
abnormal bone mineralization 36 | 38
abnormal cranium morphology 36 | 36
increased circulating chloride... 36 | 41
tremors 35 | 39
increased grip strength 34 | 41
prolonged QT interval 34 | 38

Disease

Carcinoma 9,494 | 11,192
ovarian cancer 7,895 | 8,297
osteosarcoma 7,271 | 7,766
medulloblastoma, large-cell 5,656 | 6,086
psoriasis 5,559 | 6,514
glioblastoma 5,343 | 5,635
atypical teratoid / rhabdoid tumor 4,693 | 4,971
lung cancer 4,352 | 4,607
ependymoma 4,279 | 4,559
group 3 medulloblastoma 3,772 | 4,002
adult high grade glioma 3,421 | 3,701
Breast cancer 3,284 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,090 | 3,204
malignant mesothelioma 3,006 | 3,135
intraductal papillary-mucinous carcinoma (IPMC) 2,813 | 2,902
invasive ductal carcinoma 2,806 | 2,867
Astrocytoma, Pilocytic 2,805 | 3,006
primitive neuroectodermal tumor 2,801 | 2,957
intraductal papillary-mucinous adenoma (IPMA) 2,780 | 2,872
non-small cell lung cancer 2,686 | 2,799
oligodendroglioma 2,604 | 2,768
lung carcinoma 2,572 | 2,755
lung adenocarcinoma 2,475 | 2,627
astrocytic glioma 2,399 | 2,530
Kidney cancer 2,249 | 2,548
pancreatic cancer 2,212 | 2,322
interstitial cystitis 2,133 | 2,237
subependymal giant cell astrocytoma 2,119 | 2,230
Cancer 2,118 | 2,388
tuberculosis 1,869 | 1,963
pancreatic ductal adenocarcinoma liver metastasis 1,821 | 1,911
Pick disease 1,795 | 1,856
pituitary cancer 1,787 | 1,915
group 4 medulloblastoma 1,724 | 1,806
ulcerative colitis 1,698 | 1,765
ductal carcinoma in situ 1,647 | 1,686
cystic fibrosis 1,545 | 1,629
breast carcinoma 1,530 | 1,589
colon cancer 1,391 | 1,428
adrenocortical carcinoma 1,350 | 1,385
diabetes mellitus 1,288 | 1,683
Multiple myeloma 1,271 | 1,296
Autosomal recessive predisposition 1,243 | 1,407
juvenile dermatomyositis 1,119 | 1,147
acute quadriplegic myopathy 1,101 | 1,133
astrocytoma 1,071 | 1,113
Rheumatoid arthritis 1,051 | 1,156
primary pancreatic ductal adenocarcinoma 1,044 | 1,071
spina bifida 995 | 1,053
pediatric high grade glioma 986 | 1,035
Schizophrenia 976 | 1,136
cutaneous lupus erythematosus 962 | 1,016
nasopharyngeal carcinoma 948 | 1,024
Intellectual disability 924 | 998
dermatomyositis 891 | 941
active Crohn's disease 844 | 882
Atopic dermatitis 826 | 915
non primary Sjogren syndrome sicca 780 | 861
acute myeloid leukemia 744 | 760
gastric carcinoma 740 | 781
Waldenstrons macroglobulinemia 732 | 742
Epilepsy 715 | 775
active ulcerative colitis 702 | 736
primary Sjogren syndrome 688 | 710
Liver Cirrhosis, Experimental 686 | 733
esophageal adenocarcinoma 662 | 696
medulloblastoma 662 | 702
progressive supranuclear palsy 633 | 656
aldosterone-producing adenoma 631 | 646
Dull intelligence 586 | 634
Low intelligence 586 | 634
Mental Retardation 586 | 634
Mental deficiency 586 | 634
Poor school performance 586 | 634
Alzheimer's disease 583 | 640
Obesity 567 | 655
Cognitive delay 560 | 596
Duchenne muscular dystrophy 560 | 587
Global developmental delay 560 | 596
Mental and motor retardation 560 | 596
Bipolar Disorder 546 | 646
Melanoma 545 | 689
Seizures 541 | 584
pancreatic carcinoma 540 | 555
Muscle hypotonia 533 | 562
fibroadenoma 524 | 538
hepatocellular carcinoma 520 | 536
Liver cancer 496 | 589
Endometriosis 484 | 521
autosomal dominant Emery-Dreifuss muscular dystrophy 479 | 492
Short stature 471 | 514
chronic rhinosinusitis 455 | 505
Down syndrome 453 | 480
Prostatic Neoplasms 439 | 472
mucosa-associated lymphoid tissue lymphoma 439 | 473
Multiple Sclerosis 437 | 527
posterior fossa group A ependymoma 437 | 456
sonic hedgehog group medulloblastoma 437 | 459
gastric cancer 436 | 445
Amyotrophic lateral sclerosis 417 | 437

Tissue

Skin and soft tissues 15,857 | 17,230
Endocrine System 15,813 | 18,159
Female tissues 15,802 | 17,400
Digestive Tract 15,797 | 17,369
Male tissues 15,712 | 17,142
Liver and Pancreas 15,641 | 16,750
Urinary Tract 15,597 | 16,678
Blood and immune system 15,587 | 16,909
Nervous System 15,472 | 16,725
Respiratory system 15,456 | 16,393
Cardiovascular System 14,713 | 15,192

Target Family

Non-IDG 9,220 | 12,091
Enzyme 3,663 | 4,145
Transcription Factor 1,162 | 1,400
Kinase 590 | 634
Transporter 387 | 473
GPCR 271 | 408
Ion Channel 249 | 344
Epigenetic 229 | 242
Nuclear Receptor 42 | 48
TF/Epigenetic 33 | 38
oGPCR 11 | 421

HPA RNA Tissue

smooth muscle 15,857 | 15,857
testis 17,936 | 17,936
cerebral cortex 16,630 | 16,630
prostate 16,460 | 16,460
endometrium 16,349 | 16,349
gallbladder 16,333 | 16,333
lung 16,312 | 16,312
appendix 16,247 | 16,247
fallopian tube 16,245 | 16,245
skin 16,206 | 16,206
small intestine 16,154 | 16,154
stomach 16,099 | 16,099
breast 16,063 | 16,063
duodenum 15,975 | 15,975
spleen 15,972 | 15,972
adrenal gland 15,963 | 15,963
colon 15,959 | 15,959
thyroid gland 15,959 | 15,959
placenta 15,937 | 15,937
seminal vesicle 15,918 | 15,918
kidney 15,917 | 15,917
esophagus 15,898 | 15,898
cervix, uterine 15,871 | 15,871
epididymis 15,863 | 15,863
adipose tissue 15,837 | 15,837
lymph node 15,833 | 15,833
urinary bladder 15,814 | 15,814
rectum 15,705 | 15,705
ovary 15,408 | 15,408
tonsil 15,400 | 15,400
salivary gland 14,981 | 14,981
heart muscle 14,972 | 14,972
parathyroid gland 14,769 | 14,769
liver 14,587 | 14,587
bone marrow 14,571 | 14,571
pancreas 14,070 | 14,070
skeletal muscle 14,011 | 14,011

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15
DENN domain-containing protein 1A DENND1A Tbio Non-IDG -1.14835 13.7 90
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
General transcription factor IIE subunit 1 GTF2E1 Tbio Non-IDG 0.16 0.68 153
Neutral alpha-glucosidase C GANC Tchem Enzyme -1.74673 51.7 93
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.03938 994.7 101
Vascular endothelial zinc finger 1 VEZF1 Tbio Transcription Factor -2.04566 107.4 83