Development Level

Tbio 10,179 | 11,445
Tdark 3,979 | 6,588
Tchem 1,456 | 1,598
Tclin 540 | 613

Collection

RFA-RM-18-021 261 | 328
Kinase: IDG Consortium (Target... 116 | 125
Ion Channel: IDG Consortium (T... 77 | 99
GPCR: IDG Consortium (Targets) 69 | 126
Kinase: IDG Consortium (Comple... 32 | 37
GPCR: IDG Consortium (Complete... 20 | 25

IMPC Phenotype

preweaning lethality, complete... 949 | 979
preweaning lethality, incomple... 472 | 499
abnormal behavior 281 | 298
embryonic lethality prior to t... 273 | 278
embryonic lethality prior to o... 237 | 239
abnormal embryo size 210 | 220
decreased total body fat amoun... 191 | 207
enlarged heart 188 | 210
abnormal bone structure 170 | 187
decreased vertical activity 170 | 208
increased lean body mass 157 | 172
decreased body weight 152 | 161
abnormal heart morphology 146 | 162
decreased bone mineral content 141 | 151
hyperactivity 139 | 148
decreased lean body mass 128 | 135
increased total body fat amoun... 124 | 134
decreased bone mineral density 117 | 126
decreased circulating glucose ... 114 | 126
hypoactivity 114 | 132
increased circulating alkaline... 112 | 122
decreased grip strength 108 | 116
increased startle reflex 103 | 112
embryonic growth retardation 101 | 106
abnormal seminal vesicle morph... 100 | 114
increased bone mineral content 100 | 108
male infertility 100 | 123
decreased body length 95 | 101
increased or absent threshold ... 93 | 101
short tibia 92 | 97
decreased circulating choleste... 90 | 93
increased mean corpuscular hem... 89 | 96
increased mean corpuscular vol... 88 | 92
cataract 87 | 92
prenatal lethality prior to he... 85 | 87
decreased lymphocyte cell numb... 79 | 83
decreased circulating serum al... 77 | 82
decreased circulating triglyce... 77 | 79
abnormal lens morphology 76 | 81
decreased prepulse inhibition 76 | 82
decreased mean corpuscular vol... 71 | 79
decreased leukocyte cell numbe... 70 | 73
impaired glucose tolerance 70 | 75
increased circulating HDL chol... 70 | 80
increased fasted circulating g... 70 | 76
improved glucose tolerance 69 | 79
decreased circulating insulin ... 68 | 76
decreased startle reflex 67 | 75
increased bone mineral density 67 | 72
abnormal retina morphology 66 | 71
decreased circulating HDL chol... 66 | 68
abnormal eye morphology 65 | 68
abnormal gait 65 | 69
abnormal sleep behavior 65 | 70
increased circulating sodium l... 65 | 71
small superior vagus ganglion 64 | 74
decreased fasted circulating g... 61 | 65
abnormal behavioral response t... 60 | 66
increased circulating choleste... 60 | 66
abnormal kidney morphology 59 | 65
decreased erythrocyte cell num... 59 | 62
increased monocyte cell number 59 | 63
abnormal coat-hair pigmentatio... 58 | 64
decreased hemoglobin content 58 | 68
edema 56 | 59
increased heart weight 55 | 62
decreased caudal vertebrae num... 53 | 53
small testis 53 | 58
thrombocytopenia 52 | 56
abnormal spleen morphology 51 | 55
female infertility 49 | 60
decreased circulating total pr... 48 | 49
abnormal skin morphology 47 | 50
decreased blood urea nitrogen ... 47 | 51
increased blood urea nitrogen ... 45 | 48
abnormal neural tube closure 44 | 46
decreased circulating alanine ... 44 | 47
decreased mean corpuscular hem... 44 | 50
decreased circulating alkaline... 43 | 46
hydrometra 43 | 53
increased neutrophil cell numb... 43 | 46
decreased hematocrit 42 | 46
increased leukocyte cell numbe... 42 | 47
decreased neutrophil cell numb... 40 | 42
increased hematocrit 40 | 46
decreased red blood cell distr... 39 | 41
abnormal testis morphology 38 | 43
enlarged spleen 38 | 41
increased circulating chloride... 38 | 41
increased circulating triglyce... 38 | 42
increased hemoglobin content 38 | 45
increased mean platelet volume 38 | 45
decreased circulating LDL chol... 37 | 38
limb grasping 37 | 41
abnormal bone mineralization 36 | 38
abnormal cranium morphology 36 | 36
tremors 36 | 39
increased circulating creatini... 35 | 38
increased erythrocyte cell num... 35 | 39
increased grip strength 34 | 41

Disease

Carcinoma 9,834 | 11,493
ovarian cancer 8,149 | 8,520
osteosarcoma 7,489 | 7,950
medulloblastoma, large-cell 5,820 | 6,241
psoriasis 5,768 | 6,694
glioblastoma 5,517 | 5,792
atypical teratoid / rhabdoid tumor 4,842 | 5,112
lung cancer 4,462 | 4,740
ependymoma 4,391 | 4,679
group 3 medulloblastoma 3,891 | 4,104
adult high grade glioma 3,543 | 3,801
Breast cancer 3,378 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,207 | 3,291
malignant mesothelioma 3,113 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 2,922 | 2,989
Astrocytoma, Pilocytic 2,896 | 3,081
invasive ductal carcinoma 2,887 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 2,878 | 2,955
primitive neuroectodermal tumor 2,875 | 3,035
non-small cell lung cancer 2,751 | 2,890
oligodendroglioma 2,693 | 2,850
lung carcinoma 2,678 | 2,843
lung adenocarcinoma 2,556 | 2,716
astrocytic glioma 2,457 | 2,597
Kidney cancer 2,297 | 2,613
pancreatic cancer 2,283 | 2,398
Cancer 2,238 | 2,499
interstitial cystitis 2,204 | 2,312
subependymal giant cell astrocytoma 2,187 | 2,287
tuberculosis 1,923 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 1,896 | 1,962
pituitary cancer 1,856 | 1,972
Pick disease 1,836 | 1,894
group 4 medulloblastoma 1,770 | 1,855
ulcerative colitis 1,759 | 1,819
ductal carcinoma in situ 1,695 | 1,745
cystic fibrosis 1,593 | 1,696
breast carcinoma 1,580 | 1,638
colon cancer 1,434 | 1,478
adrenocortical carcinoma 1,394 | 1,428
diabetes mellitus 1,373 | 1,728
Multiple myeloma 1,312 | 1,332
Autosomal recessive predisposition 1,301 | 1,442
juvenile dermatomyositis 1,158 | 1,187
acute quadriplegic myopathy 1,127 | 1,158
astrocytoma 1,111 | 1,146
primary pancreatic ductal adenocarcinoma 1,086 | 1,109
Rheumatoid arthritis 1,085 | 1,191
pediatric high grade glioma 1,022 | 1,064
spina bifida 1,021 | 1,074
Schizophrenia 1,011 | 1,160
cutaneous lupus erythematosus 1,005 | 1,057
nasopharyngeal carcinoma 958 | 1,058
Intellectual disability 943 | 1,016
dermatomyositis 916 | 966
active Crohn's disease 898 | 922
Atopic dermatitis 859 | 952
non primary Sjogren syndrome sicca 819 | 891
gastric carcinoma 779 | 807
acute myeloid leukemia 771 | 783
Waldenstrons macroglobulinemia 760 | 765
Liver Cirrhosis, Experimental 737 | 769
Epilepsy 734 | 792
active ulcerative colitis 734 | 764
primary Sjogren syndrome 719 | 735
esophageal adenocarcinoma 692 | 737
medulloblastoma 682 | 720
progressive supranuclear palsy 654 | 676
aldosterone-producing adenoma 650 | 665
Obesity 618 | 678
Alzheimer's disease 607 | 658
Dull intelligence 599 | 645
Low intelligence 599 | 645
Mental Retardation 599 | 645
Mental deficiency 599 | 645
Poor school performance 599 | 645
Bipolar Disorder 579 | 666
Cognitive delay 578 | 608
Global developmental delay 578 | 608
Mental and motor retardation 578 | 608
Duchenne muscular dystrophy 575 | 601
Melanoma 566 | 711
Seizures 557 | 596
pancreatic carcinoma 545 | 562
fibroadenoma 543 | 559
Muscle hypotonia 540 | 571
hepatocellular carcinoma 536 | 547
Liver cancer 507 | 604
Endometriosis 501 | 540
autosomal dominant Emery-Dreifuss muscular dystrophy 498 | 510
Short stature 485 | 531
Down syndrome 475 | 499
Prostatic Neoplasms 471 | 495
chronic rhinosinusitis 461 | 512
Multiple Sclerosis 458 | 540
mucosa-associated lymphoid tissue lymphoma 450 | 484
gastric cancer 449 | 459
posterior fossa group A ependymoma 447 | 468
sonic hedgehog group medulloblastoma 442 | 467
Amyotrophic lateral sclerosis 428 | 451

Tissue

Digestive Tract 16,154 | 17,369
Endocrine System 16,087 | 18,159
Female tissues 16,003 | 17,400
Skin and soft tissues 15,976 | 17,230
Male tissues 15,910 | 17,142
Liver and Pancreas 15,868 | 16,750
Blood and immune system 15,828 | 16,909
Urinary Tract 15,778 | 16,678
Nervous System 15,692 | 16,725
Respiratory system 15,637 | 16,393
Cardiovascular System 14,782 | 15,192

Target Family

Non-IDG 9,365 | 12,091
Enzyme 3,741 | 4,145
Transcription Factor 1,181 | 1,400
Kinase 597 | 634
Transporter 401 | 473
GPCR 280 | 408
Ion Channel 271 | 344
Epigenetic 229 | 242
Nuclear Receptor 44 | 48
TF/Epigenetic 35 | 38
oGPCR 10 | 421

HPA RNA Tissue

small intestine 16,154 | 16,154
testis 17,936 | 17,936
cerebral cortex 16,630 | 16,630
prostate 16,460 | 16,460
endometrium 16,349 | 16,349
gallbladder 16,333 | 16,333
lung 16,312 | 16,312
appendix 16,247 | 16,247
fallopian tube 16,245 | 16,245
skin 16,206 | 16,206
stomach 16,099 | 16,099
breast 16,063 | 16,063
duodenum 15,975 | 15,975
spleen 15,972 | 15,972
adrenal gland 15,963 | 15,963
colon 15,959 | 15,959
thyroid gland 15,959 | 15,959
placenta 15,937 | 15,937
seminal vesicle 15,918 | 15,918
kidney 15,917 | 15,917
esophagus 15,898 | 15,898
cervix, uterine 15,871 | 15,871
epididymis 15,863 | 15,863
smooth muscle 15,857 | 15,857
adipose tissue 15,837 | 15,837
lymph node 15,833 | 15,833
urinary bladder 15,814 | 15,814
rectum 15,705 | 15,705
ovary 15,408 | 15,408
tonsil 15,400 | 15,400
salivary gland 14,981 | 14,981
heart muscle 14,972 | 14,972
parathyroid gland 14,769 | 14,769
liver 14,587 | 14,587
bone marrow 14,571 | 14,571
pancreas 14,070 | 14,070
skeletal muscle 14,011 | 14,011

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carcinoembryonic antigen-related cell adhesion molecule 8 CEACAM8 Tbio Non-IDG -2.27709 182.9 314
DmX-like protein 1 DMXL1 Tdark Non-IDG -2.50063 311.1 13
Zinc finger protein 175 ZNF175 Tbio Transcription Factor -0.86533 8.35 88
RWD domain-containing protein 3 RWDD3 Tbio Non-IDG -1.02793 10.9 98
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
UPF0606 protein KIAA1549 KIAA1549 Tbio Non-IDG -1.67668 47.8 19
Uncharacterized protein KIAA1551 KIAA1551 Tdark Non-IDG -0.49946 2.76 22
WD repeat domain phosphoinositide-interacting protein 4 WDR45 Tbio Non-IDG -1.29355 17.4 93
GPI mannosyltransferase 4 PIGZ Tdark Enzyme -1.18571 13.8 39