Development Level

Tbio 9,859 | 11,178
Tdark 3,889 | 6,569
Tchem 1,679 | 1,885
Tclin 510 | 612

Collection

Kinase: IDG Consortium (Target... 110 | 125
GPCR: IDG Consortium (Targets) 73 | 126
Ion Channel: IDG Consortium (T... 73 | 99
Kinase: IDG Consortium (Comple... 34 | 37
GPCR: IDG Consortium (Complete... 19 | 25

IMPC Phenotype

preweaning lethality, complete... 951 | 979
preweaning lethality, incomple... 467 | 499
embryonic lethality prior to t... 275 | 278
abnormal behavior 268 | 298
embryonic lethality prior to o... 237 | 239
abnormal embryo size 214 | 220
decreased total body fat amoun... 190 | 207
enlarged heart 187 | 210
decreased vertical activity 172 | 208
abnormal bone structure 162 | 187
increased lean body mass 155 | 172
decreased body weight 152 | 161
abnormal heart morphology 145 | 162
decreased bone mineral content 135 | 151
hyperactivity 129 | 148
decreased lean body mass 123 | 135
increased total body fat amoun... 120 | 134
hypoactivity 115 | 132
decreased bone mineral density 112 | 126
decreased circulating glucose ... 111 | 126
increased circulating alkaline... 109 | 122
male infertility 105 | 123
abnormal seminal vesicle morph... 104 | 114
embryonic growth retardation 103 | 106
increased startle reflex 103 | 112
decreased grip strength 97 | 116
increased bone mineral content 96 | 108
decreased body length 93 | 101
short tibia 93 | 97
increased or absent threshold ... 90 | 101
cataract 89 | 92
increased mean corpuscular vol... 89 | 92
increased mean corpuscular hem... 88 | 96
decreased circulating choleste... 85 | 93
prenatal lethality prior to he... 83 | 87
abnormal lens morphology 78 | 81
decreased circulating serum al... 77 | 82
decreased lymphocyte cell numb... 77 | 83
decreased circulating triglyce... 74 | 79
decreased mean corpuscular vol... 72 | 79
decreased prepulse inhibition 70 | 82
decreased startle reflex 70 | 75
increased bone mineral density 70 | 72
increased circulating HDL chol... 69 | 80
small superior vagus ganglion 69 | 74
decreased leukocyte cell numbe... 68 | 73
decreased circulating insulin ... 67 | 76
improved glucose tolerance 67 | 79
increased fasted circulating g... 67 | 76
abnormal eye morphology 66 | 68
impaired glucose tolerance 66 | 75
abnormal retina morphology 65 | 71
abnormal sleep behavior 62 | 70
decreased circulating HDL chol... 62 | 68
abnormal coat-hair pigmentatio... 60 | 64
abnormal gait 60 | 69
abnormal kidney morphology 60 | 65
decreased erythrocyte cell num... 60 | 62
increased circulating sodium l... 59 | 71
increased monocyte cell number 59 | 63
decreased hemoglobin content 58 | 68
increased circulating choleste... 58 | 66
abnormal behavioral response t... 57 | 66
edema 57 | 59
increased heart weight 56 | 62
decreased fasted circulating g... 55 | 65
small testis 53 | 58
thrombocytopenia 52 | 56
abnormal spleen morphology 50 | 55
decreased caudal vertebrae num... 50 | 53
female infertility 49 | 60
hydrometra 49 | 53
abnormal skin morphology 47 | 50
decreased circulating total pr... 47 | 49
abnormal neural tube closure 46 | 46
decreased blood urea nitrogen ... 46 | 51
decreased mean corpuscular hem... 45 | 50
decreased circulating alanine ... 43 | 47
decreased circulating alkaline... 42 | 46
increased blood urea nitrogen ... 42 | 48
increased hematocrit 42 | 46
increased neutrophil cell numb... 42 | 46
decreased hematocrit 41 | 46
increased leukocyte cell numbe... 41 | 47
abnormal testis morphology 40 | 43
enlarged spleen 40 | 41
increased mean platelet volume 40 | 45
decreased neutrophil cell numb... 39 | 42
decreased red blood cell distr... 38 | 41
increased hemoglobin content 38 | 45
abnormal bone mineralization 37 | 38
increased circulating triglyce... 37 | 42
decreased circulating LDL chol... 36 | 38
decreased circulating creatini... 35 | 39
increased erythrocyte cell num... 35 | 39
tremors 35 | 39
abnormal cranium morphology 34 | 36
abnormal epididymis morphology 34 | 42
decreased circulating aspartat... 33 | 34
pallor 33 | 34

Disease

Carcinoma 9,456 | 11,192
ovarian cancer 7,863 | 8,297
osteosarcoma 7,274 | 7,766
medulloblastoma, large-cell 5,573 | 6,086
psoriasis 5,526 | 6,514
glioblastoma 5,242 | 5,635
atypical teratoid / rhabdoid tumor 4,592 | 4,971
lung cancer 4,337 | 4,607
ependymoma 4,156 | 4,559
group 3 medulloblastoma 3,693 | 4,002
adult high grade glioma 3,335 | 3,701
Breast cancer 3,269 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,069 | 3,204
malignant mesothelioma 3,025 | 3,135
invasive ductal carcinoma 2,788 | 2,867
intraductal papillary-mucinous carcinoma (IPMC) 2,787 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,755 | 2,872
primitive neuroectodermal tumor 2,725 | 2,957
Astrocytoma, Pilocytic 2,709 | 3,006
non-small cell lung cancer 2,699 | 2,799
lung carcinoma 2,521 | 2,755
oligodendroglioma 2,513 | 2,768
lung adenocarcinoma 2,480 | 2,627
astrocytic glioma 2,310 | 2,530
pancreatic cancer 2,204 | 2,322
Kidney cancer 2,203 | 2,548
interstitial cystitis 2,121 | 2,237
Cancer 2,115 | 2,388
subependymal giant cell astrocytoma 2,073 | 2,230
tuberculosis 1,873 | 1,963
pancreatic ductal adenocarcinoma liver metastasis 1,818 | 1,911
pituitary cancer 1,754 | 1,915
Pick disease 1,742 | 1,856
group 4 medulloblastoma 1,703 | 1,806
ulcerative colitis 1,675 | 1,765
ductal carcinoma in situ 1,632 | 1,686
cystic fibrosis 1,550 | 1,629
breast carcinoma 1,524 | 1,589
adrenocortical carcinoma 1,349 | 1,385
colon cancer 1,343 | 1,428
diabetes mellitus 1,291 | 1,683
Multiple myeloma 1,271 | 1,296
Autosomal recessive predisposition 1,249 | 1,407
juvenile dermatomyositis 1,117 | 1,147
acute quadriplegic myopathy 1,101 | 1,133
astrocytoma 1,063 | 1,113
Rheumatoid arthritis 1,050 | 1,156
primary pancreatic ductal adenocarcinoma 1,048 | 1,071
spina bifida 1,004 | 1,053
pediatric high grade glioma 983 | 1,035
cutaneous lupus erythematosus 966 | 1,016
nasopharyngeal carcinoma 950 | 1,024
Schizophrenia 947 | 1,136
Intellectual disability 909 | 998
dermatomyositis 893 | 941
active Crohn's disease 831 | 882
Atopic dermatitis 826 | 915
non primary Sjogren syndrome sicca 789 | 861
acute myeloid leukemia 753 | 760
gastric carcinoma 741 | 781
Waldenstrons macroglobulinemia 737 | 742
Epilepsy 692 | 775
primary Sjogren syndrome 687 | 710
Liver Cirrhosis, Experimental 686 | 733
active ulcerative colitis 679 | 736
esophageal adenocarcinoma 658 | 696
medulloblastoma 650 | 702
aldosterone-producing adenoma 625 | 646
progressive supranuclear palsy 622 | 656
Dull intelligence 580 | 634
Low intelligence 580 | 634
Mental Retardation 580 | 634
Mental deficiency 580 | 634
Poor school performance 580 | 634
Alzheimer's disease 576 | 640
Obesity 567 | 655
Duchenne muscular dystrophy 563 | 587
Cognitive delay 562 | 596
Global developmental delay 562 | 596
Mental and motor retardation 562 | 596
pancreatic carcinoma 542 | 555
Seizures 533 | 584
Bipolar Disorder 531 | 646
Melanoma 531 | 689
Muscle hypotonia 525 | 562
hepatocellular carcinoma 524 | 536
fibroadenoma 516 | 538
Liver cancer 488 | 589
Endometriosis 485 | 521
autosomal dominant Emery-Dreifuss muscular dystrophy 480 | 492
Short stature 472 | 514
chronic rhinosinusitis 468 | 505
Down syndrome 453 | 480
mucosa-associated lymphoid tissue lymphoma 450 | 473
Prostatic Neoplasms 441 | 472
gastric cancer 435 | 445
posterior fossa group A ependymoma 431 | 456
sonic hedgehog group medulloblastoma 431 | 459
Multiple Sclerosis 430 | 527
Amyotrophic lateral sclerosis 415 | 437

Tissue

Female tissues 15,937 | 17,400
Endocrine System 15,889 | 18,159
Digestive Tract 15,776 | 17,369
Skin and soft tissues 15,743 | 17,230
Male tissues 15,673 | 17,142
Blood and immune system 15,663 | 16,909
Liver and Pancreas 15,580 | 16,750
Urinary Tract 15,543 | 16,678
Respiratory system 15,474 | 16,393
Nervous System 15,445 | 16,725
Cardiovascular System 14,680 | 15,192

Target Family

Non-IDG 9,276 | 12,091
Enzyme 3,684 | 4,145
Transcription Factor 1,167 | 1,400
Kinase 583 | 634
Transporter 375 | 473
GPCR 275 | 408
Ion Channel 251 | 344
Epigenetic 227 | 242
Nuclear Receptor 40 | 48
TF/Epigenetic 35 | 38
oGPCR 24 | 421

HPA RNA Tissue

placenta 15,937 | 15,937
testis 17,936 | 17,936
cerebral cortex 16,630 | 16,630
prostate 16,460 | 16,460
endometrium 16,349 | 16,349
gallbladder 16,333 | 16,333
lung 16,312 | 16,312
appendix 16,247 | 16,247
fallopian tube 16,245 | 16,245
skin 16,206 | 16,206
small intestine 16,154 | 16,154
stomach 16,099 | 16,099
breast 16,063 | 16,063
duodenum 15,975 | 15,975
spleen 15,972 | 15,972
adrenal gland 15,963 | 15,963
colon 15,959 | 15,959
thyroid gland 15,959 | 15,959
seminal vesicle 15,918 | 15,918
kidney 15,917 | 15,917
esophagus 15,898 | 15,898
cervix, uterine 15,871 | 15,871
epididymis 15,863 | 15,863
smooth muscle 15,857 | 15,857
adipose tissue 15,837 | 15,837
lymph node 15,833 | 15,833
urinary bladder 15,814 | 15,814
rectum 15,705 | 15,705
ovary 15,408 | 15,408
tonsil 15,400 | 15,400
salivary gland 14,981 | 14,981
heart muscle 14,972 | 14,972
parathyroid gland 14,769 | 14,769
liver 14,587 | 14,587
bone marrow 14,571 | 14,571
pancreas 14,070 | 14,070
skeletal muscle 14,011 | 14,011

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15
DENN domain-containing protein 1A DENND1A Tbio Non-IDG -1.14835 13.7 90
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
Melanoma-associated antigen 9 MAGEA9B Tbio Non-IDG -1.32496 23.3 213
Melanoma-associated antigen 11 MAGEA11 Tbio Non-IDG -1.28291 22.2 180
General transcription factor IIE subunit 1 GTF2E1 Tbio Non-IDG 0.16 0.68 153
Neutral alpha-glucosidase C GANC Tchem Enzyme -1.74673 51.7 93