Development Level

Tbio 9,500 | 11,178
Tdark 3,800 | 6,569
Tchem 1,619 | 1,885
Tclin 489 | 612

Collection

Kinase: IDG Consortium (Target... 111 | 125
Ion Channel: IDG Consortium (T... 68 | 99
GPCR: IDG Consortium (Targets) 61 | 126
Kinase: IDG Consortium (Comple... 35 | 37
GPCR: IDG Consortium (Complete... 18 | 25

IMPC Phenotype

preweaning lethality, complete... 936 | 979
preweaning lethality, incomple... 453 | 499
abnormal behavior 269 | 298
embryonic lethality prior to t... 266 | 278
embryonic lethality prior to o... 236 | 239
abnormal embryo size 208 | 220
decreased total body fat amoun... 186 | 207
enlarged heart 175 | 210
abnormal bone structure 162 | 187
decreased vertical activity 158 | 208
increased lean body mass 154 | 172
decreased body weight 146 | 161
abnormal heart morphology 140 | 162
decreased bone mineral content 131 | 151
hyperactivity 131 | 148
decreased lean body mass 123 | 135
increased total body fat amoun... 118 | 134
hypoactivity 117 | 132
increased circulating alkaline... 110 | 122
decreased bone mineral density 109 | 126
decreased circulating glucose ... 108 | 126
increased startle reflex 103 | 112
embryonic growth retardation 100 | 106
male infertility 99 | 123
decreased grip strength 97 | 116
abnormal seminal vesicle morph... 96 | 114
increased bone mineral content 96 | 108
decreased body length 91 | 101
short tibia 90 | 97
increased mean corpuscular vol... 89 | 92
increased or absent threshold ... 88 | 101
cataract 87 | 92
decreased circulating choleste... 84 | 93
increased mean corpuscular hem... 84 | 96
prenatal lethality prior to he... 81 | 87
abnormal lens morphology 76 | 81
decreased lymphocyte cell numb... 75 | 83
decreased circulating serum al... 74 | 82
decreased prepulse inhibition 71 | 82
decreased mean corpuscular vol... 70 | 79
decreased circulating triglyce... 69 | 79
increased bone mineral density 69 | 72
increased circulating HDL chol... 69 | 80
increased fasted circulating g... 69 | 76
improved glucose tolerance 68 | 79
decreased leukocyte cell numbe... 67 | 73
decreased startle reflex 67 | 75
abnormal retina morphology 65 | 71
abnormal eye morphology 63 | 68
decreased circulating HDL chol... 62 | 68
impaired glucose tolerance 62 | 75
decreased circulating insulin ... 61 | 76
small superior vagus ganglion 61 | 74
abnormal sleep behavior 60 | 70
abnormal behavioral response t... 58 | 66
abnormal gait 58 | 69
decreased hemoglobin content 58 | 68
increased circulating choleste... 58 | 66
increased circulating sodium l... 58 | 71
abnormal coat-hair pigmentatio... 57 | 64
decreased erythrocyte cell num... 57 | 62
decreased fasted circulating g... 57 | 65
edema 55 | 59
increased monocyte cell number 55 | 63
abnormal kidney morphology 54 | 65
increased heart weight 54 | 62
decreased caudal vertebrae num... 52 | 53
small testis 52 | 58
thrombocytopenia 50 | 56
abnormal spleen morphology 48 | 55
female infertility 48 | 60
decreased circulating total pr... 47 | 49
abnormal skin morphology 45 | 50
decreased mean corpuscular hem... 45 | 50
abnormal neural tube closure 44 | 46
decreased blood urea nitrogen ... 44 | 51
increased leukocyte cell numbe... 44 | 47
decreased circulating alkaline... 43 | 46
hydrometra 43 | 53
increased hematocrit 43 | 46
decreased circulating alanine ... 42 | 47
increased blood urea nitrogen ... 42 | 48
decreased hematocrit 41 | 46
increased neutrophil cell numb... 41 | 46
increased mean platelet volume 40 | 45
abnormal testis morphology 38 | 43
decreased neutrophil cell numb... 38 | 42
decreased red blood cell distr... 38 | 41
enlarged spleen 38 | 41
increased hemoglobin content 38 | 45
increased circulating triglyce... 37 | 42
abnormal bone mineralization 36 | 38
decreased circulating LDL chol... 36 | 38
increased erythrocyte cell num... 36 | 39
increased grip strength 36 | 41
tremors 36 | 39
decreased circulating creatini... 35 | 39
increased circulating chloride... 35 | 41
enlarged lymph nodes 34 | 37
abnormal cranium morphology 33 | 36

Disease

Carcinoma 9,211 | 11,192
ovarian cancer 7,780 | 8,297
osteosarcoma 7,095 | 7,766
medulloblastoma, large-cell 5,504 | 6,086
psoriasis 5,278 | 6,514
glioblastoma 5,207 | 5,635
atypical teratoid / rhabdoid tumor 4,555 | 4,971
lung cancer 4,262 | 4,607
ependymoma 4,143 | 4,559
group 3 medulloblastoma 3,665 | 4,002
adult high grade glioma 3,308 | 3,701
Breast cancer 3,193 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 2,996 | 3,204
malignant mesothelioma 2,945 | 3,135
invasive ductal carcinoma 2,741 | 2,867
intraductal papillary-mucinous carcinoma (IPMC) 2,734 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,709 | 2,872
Astrocytoma, Pilocytic 2,703 | 3,006
primitive neuroectodermal tumor 2,703 | 2,957
non-small cell lung cancer 2,582 | 2,799
oligodendroglioma 2,509 | 2,768
lung carcinoma 2,484 | 2,755
lung adenocarcinoma 2,358 | 2,627
astrocytic glioma 2,316 | 2,530
Kidney cancer 2,177 | 2,548
pancreatic cancer 2,123 | 2,322
subependymal giant cell astrocytoma 2,082 | 2,230
interstitial cystitis 2,038 | 2,237
Cancer 2,022 | 2,388
tuberculosis 1,826 | 1,963
pancreatic ductal adenocarcinoma liver metastasis 1,793 | 1,911
Pick disease 1,755 | 1,856
pituitary cancer 1,728 | 1,915
group 4 medulloblastoma 1,702 | 1,806
ulcerative colitis 1,624 | 1,765
ductal carcinoma in situ 1,595 | 1,686
breast carcinoma 1,484 | 1,589
cystic fibrosis 1,479 | 1,629
adrenocortical carcinoma 1,337 | 1,385
colon cancer 1,329 | 1,428
Multiple myeloma 1,270 | 1,296
diabetes mellitus 1,250 | 1,683
Autosomal recessive predisposition 1,213 | 1,407
juvenile dermatomyositis 1,105 | 1,147
acute quadriplegic myopathy 1,094 | 1,133
astrocytoma 1,057 | 1,113
primary pancreatic ductal adenocarcinoma 1,036 | 1,071
Rheumatoid arthritis 1,020 | 1,156
pediatric high grade glioma 965 | 1,035
spina bifida 962 | 1,053
Schizophrenia 937 | 1,136
cutaneous lupus erythematosus 931 | 1,016
Intellectual disability 908 | 998
nasopharyngeal carcinoma 893 | 1,024
dermatomyositis 890 | 941
active Crohn's disease 810 | 882
Atopic dermatitis 778 | 915
non primary Sjogren syndrome sicca 762 | 861
acute myeloid leukemia 739 | 760
gastric carcinoma 734 | 781
Waldenstrons macroglobulinemia 728 | 742
Epilepsy 689 | 775
Liver Cirrhosis, Experimental 677 | 733
primary Sjogren syndrome 670 | 710
active ulcerative colitis 663 | 736
medulloblastoma 651 | 702
aldosterone-producing adenoma 627 | 646
progressive supranuclear palsy 627 | 656
esophageal adenocarcinoma 611 | 696
Dull intelligence 573 | 634
Low intelligence 573 | 634
Mental Retardation 573 | 634
Mental deficiency 573 | 634
Poor school performance 573 | 634
Alzheimer's disease 564 | 640
Duchenne muscular dystrophy 559 | 587
Cognitive delay 555 | 596
Global developmental delay 555 | 596
Mental and motor retardation 555 | 596
Obesity 541 | 655
Seizures 528 | 584
pancreatic carcinoma 528 | 555
Muscle hypotonia 525 | 562
Bipolar Disorder 523 | 646
hepatocellular carcinoma 513 | 536
Melanoma 511 | 689
fibroadenoma 500 | 538
Liver cancer 482 | 589
autosomal dominant Emery-Dreifuss muscular dystrophy 475 | 492
Endometriosis 461 | 521
Short stature 461 | 514
chronic rhinosinusitis 452 | 505
Down syndrome 448 | 480
gastric cancer 424 | 445
posterior fossa group A ependymoma 424 | 456
mucosa-associated lymphoid tissue lymphoma 423 | 473
Multiple Sclerosis 422 | 527
Prostatic Neoplasms 420 | 472
sonic hedgehog group medulloblastoma 418 | 459
Amyotrophic lateral sclerosis 409 | 437

Tissue

Endocrine System 15,408 | 18,159
Female tissues 15,376 | 17,400
Digestive Tract 15,320 | 17,369
Skin and soft tissues 15,312 | 17,230
Male tissues 15,292 | 17,142
Liver and Pancreas 15,223 | 16,750
Blood and immune system 15,220 | 16,909
Urinary Tract 15,174 | 16,678
Nervous System 15,140 | 16,725
Respiratory system 15,106 | 16,393
Cardiovascular System 14,538 | 15,192

Target Family

Non-IDG 8,962 | 12,091
Enzyme 3,596 | 4,145
Transcription Factor 1,123 | 1,400
Kinase 582 | 634
Transporter 353 | 473
GPCR 248 | 408
Ion Channel 227 | 344
Epigenetic 226 | 242
Nuclear Receptor 42 | 48
TF/Epigenetic 34 | 38
oGPCR 15 | 421

HPA RNA Tissue

ovary 15,408 | 15,408
testis 17,936 | 17,936
cerebral cortex 16,630 | 16,630
prostate 16,460 | 16,460
endometrium 16,349 | 16,349
gallbladder 16,333 | 16,333
lung 16,312 | 16,312
appendix 16,247 | 16,247
fallopian tube 16,245 | 16,245
skin 16,206 | 16,206
small intestine 16,154 | 16,154
stomach 16,099 | 16,099
breast 16,063 | 16,063
duodenum 15,975 | 15,975
spleen 15,972 | 15,972
adrenal gland 15,963 | 15,963
colon 15,959 | 15,959
thyroid gland 15,959 | 15,959
placenta 15,937 | 15,937
seminal vesicle 15,918 | 15,918
kidney 15,917 | 15,917
esophagus 15,898 | 15,898
cervix, uterine 15,871 | 15,871
epididymis 15,863 | 15,863
smooth muscle 15,857 | 15,857
adipose tissue 15,837 | 15,837
lymph node 15,833 | 15,833
urinary bladder 15,814 | 15,814
rectum 15,705 | 15,705
tonsil 15,400 | 15,400
salivary gland 14,981 | 14,981
heart muscle 14,972 | 14,972
parathyroid gland 14,769 | 14,769
liver 14,587 | 14,587
bone marrow 14,571 | 14,571
pancreas 14,070 | 14,070
skeletal muscle 14,011 | 14,011

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15
DENN domain-containing protein 1A DENND1A Tbio Non-IDG -1.14835 13.7 90
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
General transcription factor IIE subunit 1 GTF2E1 Tbio Non-IDG 0.16 0.68 153
Neutral alpha-glucosidase C GANC Tchem Enzyme -1.74673 51.7 93
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.03938 994.7 101
Vascular endothelial zinc finger 1 VEZF1 Tbio Transcription Factor -2.04566 107.4 83
Histone H2B type 2-E HIST2H2BE Tbio Non-IDG -3.48425 2920.0 135