Development Level

Tbio 9,862 | 11,178
Tdark 3,866 | 6,569
Tchem 1,667 | 1,885
Tclin 503 | 612

Collection

Kinase: IDG Consortium (Target... 114 | 125
Ion Channel: IDG Consortium (T... 70 | 99
GPCR: IDG Consortium (Targets) 66 | 126
Kinase: IDG Consortium (Comple... 33 | 37
GPCR: IDG Consortium (Complete... 21 | 25

IMPC Phenotype

preweaning lethality, complete... 950 | 979
preweaning lethality, incomple... 471 | 499
abnormal behavior 276 | 298
embryonic lethality prior to t... 272 | 278
embryonic lethality prior to o... 237 | 239
abnormal embryo size 213 | 220
decreased total body fat amoun... 191 | 207
enlarged heart 190 | 210
decreased vertical activity 177 | 208
abnormal bone structure 170 | 187
increased lean body mass 157 | 172
decreased body weight 151 | 161
abnormal heart morphology 148 | 162
decreased bone mineral content 138 | 151
hyperactivity 137 | 148
decreased lean body mass 127 | 135
increased total body fat amoun... 126 | 134
hypoactivity 117 | 132
decreased bone mineral density 116 | 126
decreased circulating glucose ... 116 | 126
increased circulating alkaline... 111 | 122
male infertility 105 | 123
decreased grip strength 104 | 116
embryonic growth retardation 102 | 106
increased startle reflex 102 | 112
abnormal seminal vesicle morph... 98 | 114
increased bone mineral content 98 | 108
decreased body length 96 | 101
short tibia 92 | 97
increased or absent threshold ... 91 | 101
increased mean corpuscular vol... 90 | 92
decreased circulating choleste... 89 | 93
increased mean corpuscular hem... 89 | 96
cataract 85 | 92
prenatal lethality prior to he... 84 | 87
decreased lymphocyte cell numb... 78 | 83
abnormal lens morphology 76 | 81
decreased circulating serum al... 76 | 82
decreased circulating triglyce... 75 | 79
decreased prepulse inhibition 74 | 82
decreased leukocyte cell numbe... 72 | 73
decreased mean corpuscular vol... 71 | 79
decreased startle reflex 70 | 75
improved glucose tolerance 70 | 79
increased circulating HDL chol... 70 | 80
increased fasted circulating g... 70 | 76
impaired glucose tolerance 68 | 75
increased bone mineral density 68 | 72
small superior vagus ganglion 68 | 74
abnormal sleep behavior 67 | 70
decreased circulating insulin ... 67 | 76
decreased circulating HDL chol... 66 | 68
abnormal eye morphology 64 | 68
abnormal retina morphology 62 | 71
abnormal gait 61 | 69
increased circulating sodium l... 61 | 71
abnormal behavioral response t... 60 | 66
abnormal coat-hair pigmentatio... 59 | 64
decreased fasted circulating g... 59 | 65
decreased hemoglobin content 59 | 68
abnormal kidney morphology 58 | 65
decreased erythrocyte cell num... 58 | 62
increased circulating choleste... 58 | 66
increased monocyte cell number 58 | 63
edema 56 | 59
increased heart weight 56 | 62
small testis 54 | 58
decreased caudal vertebrae num... 53 | 53
thrombocytopenia 53 | 56
abnormal spleen morphology 51 | 55
female infertility 51 | 60
hydrometra 50 | 53
abnormal skin morphology 48 | 50
decreased circulating total pr... 47 | 49
decreased mean corpuscular hem... 46 | 50
abnormal neural tube closure 45 | 46
decreased blood urea nitrogen ... 45 | 51
increased hematocrit 45 | 46
decreased circulating alkaline... 44 | 46
increased leukocyte cell numbe... 44 | 47
decreased circulating alanine ... 43 | 47
increased blood urea nitrogen ... 43 | 48
decreased hematocrit 42 | 46
increased neutrophil cell numb... 42 | 46
abnormal testis morphology 40 | 43
enlarged spleen 40 | 41
increased hemoglobin content 40 | 45
decreased neutrophil cell numb... 39 | 42
increased mean platelet volume 39 | 45
decreased red blood cell distr... 38 | 41
increased circulating triglyce... 38 | 42
decreased circulating LDL chol... 36 | 38
increased erythrocyte cell num... 36 | 39
increased grip strength 36 | 41
tremors 36 | 39
abnormal bone mineralization 35 | 38
abnormal cranium morphology 35 | 36
abnormal epididymis morphology 35 | 42
decreased circulating creatini... 35 | 39
increased circulating chloride... 35 | 41

Disease

Carcinoma 9,463 | 11,192
ovarian cancer 7,878 | 8,297
osteosarcoma 7,238 | 7,766
psoriasis 5,620 | 6,514
medulloblastoma, large-cell 5,592 | 6,086
glioblastoma 5,276 | 5,635
atypical teratoid / rhabdoid tumor 4,617 | 4,971
lung cancer 4,344 | 4,607
ependymoma 4,193 | 4,559
group 3 medulloblastoma 3,734 | 4,002
adult high grade glioma 3,375 | 3,701
Breast cancer 3,292 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,094 | 3,204
malignant mesothelioma 3,016 | 3,135
intraductal papillary-mucinous carcinoma (IPMC) 2,810 | 2,902
invasive ductal carcinoma 2,803 | 2,867
intraductal papillary-mucinous adenoma (IPMA) 2,778 | 2,872
primitive neuroectodermal tumor 2,745 | 2,957
Astrocytoma, Pilocytic 2,743 | 3,006
non-small cell lung cancer 2,716 | 2,799
lung carcinoma 2,554 | 2,755
oligodendroglioma 2,554 | 2,768
lung adenocarcinoma 2,498 | 2,627
astrocytic glioma 2,344 | 2,530
Kidney cancer 2,218 | 2,548
pancreatic cancer 2,207 | 2,322
interstitial cystitis 2,141 | 2,237
Cancer 2,109 | 2,388
subependymal giant cell astrocytoma 2,094 | 2,230
tuberculosis 1,867 | 1,963
pancreatic ductal adenocarcinoma liver metastasis 1,821 | 1,911
pituitary cancer 1,767 | 1,915
Pick disease 1,765 | 1,856
group 4 medulloblastoma 1,708 | 1,806
ulcerative colitis 1,679 | 1,765
ductal carcinoma in situ 1,646 | 1,686
cystic fibrosis 1,566 | 1,629
breast carcinoma 1,537 | 1,589
colon cancer 1,369 | 1,428
adrenocortical carcinoma 1,345 | 1,385
diabetes mellitus 1,295 | 1,683
Multiple myeloma 1,271 | 1,296
Autosomal recessive predisposition 1,252 | 1,407
juvenile dermatomyositis 1,127 | 1,147
acute quadriplegic myopathy 1,120 | 1,133
astrocytoma 1,062 | 1,113
Rheumatoid arthritis 1,055 | 1,156
primary pancreatic ductal adenocarcinoma 1,039 | 1,071
spina bifida 1,026 | 1,053
pediatric high grade glioma 993 | 1,035
cutaneous lupus erythematosus 980 | 1,016
nasopharyngeal carcinoma 963 | 1,024
Schizophrenia 954 | 1,136
Intellectual disability 915 | 998
dermatomyositis 896 | 941
Atopic dermatitis 864 | 915
active Crohn's disease 840 | 882
non primary Sjogren syndrome sicca 783 | 861
acute myeloid leukemia 748 | 760
gastric carcinoma 744 | 781
Waldenstrons macroglobulinemia 735 | 742
Epilepsy 704 | 775
active ulcerative colitis 693 | 736
primary Sjogren syndrome 689 | 710
Liver Cirrhosis, Experimental 686 | 733
esophageal adenocarcinoma 683 | 696
medulloblastoma 650 | 702
progressive supranuclear palsy 629 | 656
aldosterone-producing adenoma 624 | 646
Dull intelligence 581 | 634
Low intelligence 581 | 634
Mental Retardation 581 | 634
Mental deficiency 581 | 634
Poor school performance 581 | 634
Alzheimer's disease 578 | 640
Duchenne muscular dystrophy 576 | 587
Cognitive delay 558 | 596
Global developmental delay 558 | 596
Mental and motor retardation 558 | 596
Obesity 551 | 655
Bipolar Disorder 541 | 646
pancreatic carcinoma 540 | 555
Seizures 539 | 584
Melanoma 537 | 689
Muscle hypotonia 532 | 562
fibroadenoma 523 | 538
hepatocellular carcinoma 520 | 536
autosomal dominant Emery-Dreifuss muscular dystrophy 486 | 492
Endometriosis 482 | 521
Liver cancer 481 | 589
Short stature 467 | 514
chronic rhinosinusitis 466 | 505
Down syndrome 451 | 480
mucosa-associated lymphoid tissue lymphoma 445 | 473
Prostatic Neoplasms 440 | 472
Multiple Sclerosis 438 | 527
gastric cancer 434 | 445
posterior fossa group A ependymoma 434 | 456
sonic hedgehog group medulloblastoma 426 | 459
Amyotrophic lateral sclerosis 417 | 437

Tissue

Digestive Tract 15,898 | 17,369
Endocrine System 15,836 | 18,159
Skin and soft tissues 15,832 | 17,230
Female tissues 15,803 | 17,400
Male tissues 15,727 | 17,142
Blood and immune system 15,664 | 16,909
Liver and Pancreas 15,613 | 16,750
Urinary Tract 15,592 | 16,678
Respiratory system 15,474 | 16,393
Nervous System 15,454 | 16,725
Cardiovascular System 14,803 | 15,192

Target Family

Non-IDG 9,259 | 12,091
Enzyme 3,687 | 4,145
Transcription Factor 1,161 | 1,400
Kinase 595 | 634
Transporter 382 | 473
GPCR 255 | 408
Ion Channel 243 | 344
Epigenetic 228 | 242
Nuclear Receptor 42 | 48
TF/Epigenetic 34 | 38
oGPCR 12 | 421

HPA RNA Tissue

esophagus 15,898 | 15,898
testis 17,936 | 17,936
cerebral cortex 16,630 | 16,630
prostate 16,460 | 16,460
endometrium 16,349 | 16,349
gallbladder 16,333 | 16,333
lung 16,312 | 16,312
appendix 16,247 | 16,247
fallopian tube 16,245 | 16,245
skin 16,206 | 16,206
small intestine 16,154 | 16,154
stomach 16,099 | 16,099
breast 16,063 | 16,063
duodenum 15,975 | 15,975
spleen 15,972 | 15,972
adrenal gland 15,963 | 15,963
colon 15,959 | 15,959
thyroid gland 15,959 | 15,959
placenta 15,937 | 15,937
seminal vesicle 15,918 | 15,918
kidney 15,917 | 15,917
cervix, uterine 15,871 | 15,871
epididymis 15,863 | 15,863
smooth muscle 15,857 | 15,857
adipose tissue 15,837 | 15,837
lymph node 15,833 | 15,833
urinary bladder 15,814 | 15,814
rectum 15,705 | 15,705
ovary 15,408 | 15,408
tonsil 15,400 | 15,400
salivary gland 14,981 | 14,981
heart muscle 14,972 | 14,972
parathyroid gland 14,769 | 14,769
liver 14,587 | 14,587
bone marrow 14,571 | 14,571
pancreas 14,070 | 14,070
skeletal muscle 14,011 | 14,011

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15
DENN domain-containing protein 1A DENND1A Tbio Non-IDG -1.14835 13.7 90
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
General transcription factor IIE subunit 1 GTF2E1 Tbio Non-IDG 0.16 0.68 153
Neutral alpha-glucosidase C GANC Tchem Enzyme -1.74673 51.7 93
Vascular endothelial zinc finger 1 VEZF1 Tbio Transcription Factor -2.04566 107.4 83
Histone H2B type 2-E HIST2H2BE Tbio Non-IDG -3.48425 2920.0 135