Development Level

Tbio 9,036 | 11,178
Tdark 3,564 | 6,569
Tchem 1,550 | 1,885
Tclin 421 | 612

Collection

Kinase: IDG Consortium (Target... 97 | 125
Ion Channel: IDG Consortium (T... 57 | 99
GPCR: IDG Consortium (Targets) 54 | 126
Kinase: IDG Consortium (Comple... 31 | 37
GPCR: IDG Consortium (Complete... 18 | 25

IMPC Phenotype

preweaning lethality, complete... 917 | 979
preweaning lethality, incomple... 435 | 499
embryonic lethality prior to t... 265 | 278
abnormal behavior 252 | 298
embryonic lethality prior to o... 235 | 239
abnormal embryo size 204 | 220
enlarged heart 173 | 210
decreased total body fat amoun... 172 | 207
decreased vertical activity 154 | 208
abnormal bone structure 153 | 187
increased lean body mass 144 | 172
decreased body weight 143 | 161
abnormal heart morphology 136 | 162
decreased bone mineral content 123 | 151
hyperactivity 117 | 148
decreased lean body mass 114 | 135
hypoactivity 111 | 132
increased total body fat amoun... 108 | 134
decreased bone mineral density 106 | 126
decreased circulating glucose ... 104 | 126
increased circulating alkaline... 104 | 122
embryonic growth retardation 101 | 106
decreased grip strength 97 | 116
increased startle reflex 97 | 112
increased bone mineral content 94 | 108
male infertility 93 | 123
abnormal seminal vesicle morph... 91 | 114
decreased body length 87 | 101
increased mean corpuscular hem... 87 | 96
increased mean corpuscular vol... 84 | 92
increased or absent threshold ... 84 | 101
short tibia 83 | 97
cataract 81 | 92
prenatal lethality prior to he... 81 | 87
decreased circulating choleste... 79 | 93
abnormal lens morphology 73 | 81
decreased lymphocyte cell numb... 72 | 83
decreased prepulse inhibition 70 | 82
increased bone mineral density 68 | 72
decreased circulating serum al... 67 | 82
decreased circulating triglyce... 66 | 79
increased fasted circulating g... 66 | 76
abnormal retina morphology 65 | 71
decreased mean corpuscular vol... 65 | 79
increased circulating HDL chol... 64 | 80
impaired glucose tolerance 62 | 75
abnormal sleep behavior 61 | 70
decreased leukocyte cell numbe... 61 | 73
abnormal eye morphology 60 | 68
decreased circulating HDL chol... 60 | 68
small superior vagus ganglion 60 | 74
decreased startle reflex 59 | 75
improved glucose tolerance 58 | 79
abnormal behavioral response t... 57 | 66
decreased erythrocyte cell num... 57 | 62
increased circulating sodium l... 57 | 71
decreased hemoglobin content 56 | 68
abnormal coat-hair pigmentatio... 55 | 64
abnormal gait 55 | 69
decreased circulating insulin ... 55 | 76
increased circulating choleste... 53 | 66
increased monocyte cell number 53 | 63
abnormal kidney morphology 51 | 65
decreased fasted circulating g... 51 | 65
edema 50 | 59
increased heart weight 50 | 62
thrombocytopenia 50 | 56
small testis 49 | 58
female infertility 47 | 60
decreased caudal vertebrae num... 46 | 53
abnormal spleen morphology 45 | 55
decreased circulating total pr... 44 | 49
decreased mean corpuscular hem... 44 | 50
decreased circulating alkaline... 43 | 46
abnormal neural tube closure 42 | 46
decreased circulating alanine ... 42 | 47
increased neutrophil cell numb... 42 | 46
abnormal skin morphology 41 | 50
decreased blood urea nitrogen ... 41 | 51
hydrometra 40 | 53
increased blood urea nitrogen ... 40 | 48
decreased hematocrit 39 | 46
increased hematocrit 39 | 46
increased hemoglobin content 39 | 45
decreased neutrophil cell numb... 38 | 42
increased leukocyte cell numbe... 38 | 47
increased mean platelet volume 38 | 45
decreased red blood cell distr... 36 | 41
tremors 36 | 39
abnormal testis morphology 35 | 43
enlarged spleen 35 | 41
increased erythrocyte cell num... 35 | 39
decreased circulating LDL chol... 34 | 38
abnormal bone mineralization 33 | 38
abnormal cranium morphology 33 | 36
enlarged lymph nodes 33 | 37
increased circulating chloride... 33 | 41
increased grip strength 33 | 41
decreased circulating creatini... 32 | 39
increased mean corpuscular hem... 32 | 36

Disease

Carcinoma 8,559 | 11,192
ovarian cancer 7,428 | 8,297
osteosarcoma 6,954 | 7,766
medulloblastoma, large-cell 5,111 | 6,086
psoriasis 4,915 | 6,514
glioblastoma 4,804 | 5,635
atypical teratoid / rhabdoid tumor 4,161 | 4,971
lung cancer 4,013 | 4,607
ependymoma 3,736 | 4,559
group 3 medulloblastoma 3,379 | 4,002
adult high grade glioma 2,983 | 3,701
Breast cancer 2,928 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 2,803 | 3,204
malignant mesothelioma 2,769 | 3,135
intraductal papillary-mucinous carcinoma (IPMC) 2,526 | 2,902
invasive ductal carcinoma 2,504 | 2,867
intraductal papillary-mucinous adenoma (IPMA) 2,464 | 2,872
primitive neuroectodermal tumor 2,453 | 2,957
Astrocytoma, Pilocytic 2,400 | 3,006
non-small cell lung cancer 2,400 | 2,799
oligodendroglioma 2,228 | 2,768
lung carcinoma 2,225 | 2,755
lung adenocarcinoma 2,175 | 2,627
astrocytic glioma 2,061 | 2,530
pancreatic cancer 2,006 | 2,322
Cancer 1,987 | 2,388
subependymal giant cell astrocytoma 1,926 | 2,230
Kidney cancer 1,907 | 2,548
tuberculosis 1,863 | 1,963
interstitial cystitis 1,859 | 2,237
pancreatic ductal adenocarcinoma liver metastasis 1,734 | 1,911
Pick disease 1,619 | 1,856
ulcerative colitis 1,561 | 1,765
group 4 medulloblastoma 1,555 | 1,806
pituitary cancer 1,528 | 1,915
ductal carcinoma in situ 1,431 | 1,686
breast carcinoma 1,343 | 1,589
cystic fibrosis 1,337 | 1,629
Multiple myeloma 1,266 | 1,296
adrenocortical carcinoma 1,228 | 1,385
diabetes mellitus 1,225 | 1,683
colon cancer 1,168 | 1,428
Autosomal recessive predisposition 1,159 | 1,407
juvenile dermatomyositis 1,081 | 1,147
acute quadriplegic myopathy 1,060 | 1,133
astrocytoma 1,020 | 1,113
Rheumatoid arthritis 1,007 | 1,156
primary pancreatic ductal adenocarcinoma 959 | 1,071
spina bifida 938 | 1,053
pediatric high grade glioma 911 | 1,035
dermatomyositis 877 | 941
cutaneous lupus erythematosus 862 | 1,016
Intellectual disability 852 | 998
nasopharyngeal carcinoma 852 | 1,024
Schizophrenia 821 | 1,136
active Crohn's disease 758 | 882
acute myeloid leukemia 746 | 760
Waldenstrons macroglobulinemia 737 | 742
non primary Sjogren syndrome sicca 735 | 861
Atopic dermatitis 713 | 915
gastric carcinoma 676 | 781
primary Sjogren syndrome 671 | 710
Liver Cirrhosis, Experimental 649 | 733
Epilepsy 624 | 775
active ulcerative colitis 611 | 736
progressive supranuclear palsy 598 | 656
esophageal adenocarcinoma 592 | 696
medulloblastoma 589 | 702
aldosterone-producing adenoma 572 | 646
pancreatic carcinoma 544 | 555
Dull intelligence 542 | 634
Low intelligence 542 | 634
Mental Retardation 542 | 634
Mental deficiency 542 | 634
Poor school performance 542 | 634
Cognitive delay 534 | 596
Global developmental delay 534 | 596
Mental and motor retardation 534 | 596
Alzheimer's disease 523 | 640
Duchenne muscular dystrophy 520 | 587
hepatocellular carcinoma 518 | 536
Muscle hypotonia 503 | 562
Obesity 502 | 655
Seizures 486 | 584
mucosa-associated lymphoid tissue lymphoma 453 | 473
Bipolar Disorder 451 | 646
autosomal dominant Emery-Dreifuss muscular dystrophy 441 | 492
Short stature 440 | 514
gastric cancer 434 | 445
Melanoma 425 | 689
fibroadenoma 424 | 538
Down syndrome 415 | 480
Endometriosis 413 | 521
Prostatic Neoplasms 404 | 472
Multiple Sclerosis 398 | 527
tuberculosis and treatment for 6 months 398 | 399
chronic rhinosinusitis 397 | 505
posterior fossa group A ependymoma 388 | 456
Liver cancer 383 | 589
sonic hedgehog group medulloblastoma 380 | 459

Tissue

Blood and immune system 14,571 | 16,909
Endocrine System 14,531 | 18,159
Digestive Tract 14,474 | 17,369
Female tissues 14,466 | 17,400
Skin and soft tissues 14,443 | 17,230
Male tissues 14,361 | 17,142
Liver and Pancreas 14,356 | 16,750
Respiratory system 14,280 | 16,393
Urinary Tract 14,275 | 16,678
Nervous System 14,246 | 16,725
Cardiovascular System 13,645 | 15,192

Target Family

Non-IDG 8,454 | 12,091
Enzyme 3,463 | 4,145
Transcription Factor 1,053 | 1,400
Kinase 554 | 634
Transporter 338 | 473
Epigenetic 223 | 242
GPCR 215 | 408
Ion Channel 184 | 344
Nuclear Receptor 35 | 48
TF/Epigenetic 33 | 38
oGPCR 19 | 421

HPA RNA Tissue

bone marrow 14,571 | 14,571
testis 17,936 | 17,936
cerebral cortex 16,630 | 16,630
prostate 16,460 | 16,460
endometrium 16,349 | 16,349
gallbladder 16,333 | 16,333
lung 16,312 | 16,312
appendix 16,247 | 16,247
fallopian tube 16,245 | 16,245
skin 16,206 | 16,206
small intestine 16,154 | 16,154
stomach 16,099 | 16,099
breast 16,063 | 16,063
duodenum 15,975 | 15,975
spleen 15,972 | 15,972
adrenal gland 15,963 | 15,963
colon 15,959 | 15,959
thyroid gland 15,959 | 15,959
placenta 15,937 | 15,937
seminal vesicle 15,918 | 15,918
kidney 15,917 | 15,917
esophagus 15,898 | 15,898
cervix, uterine 15,871 | 15,871
epididymis 15,863 | 15,863
smooth muscle 15,857 | 15,857
adipose tissue 15,837 | 15,837
lymph node 15,833 | 15,833
urinary bladder 15,814 | 15,814
rectum 15,705 | 15,705
ovary 15,408 | 15,408
tonsil 15,400 | 15,400
salivary gland 14,981 | 14,981
heart muscle 14,972 | 14,972
parathyroid gland 14,769 | 14,769
liver 14,587 | 14,587
pancreas 14,070 | 14,070
skeletal muscle 14,011 | 14,011

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15
DENN domain-containing protein 1A DENND1A Tbio Non-IDG -1.14835 13.7 90
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
General transcription factor IIE subunit 1 GTF2E1 Tbio Non-IDG 0.16 0.68 153
Neutral alpha-glucosidase C GANC Tchem Enzyme -1.74673 51.7 93
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.03938 994.7 101
Vascular endothelial zinc finger 1 VEZF1 Tbio Transcription Factor -2.04566 107.4 83