Development Level

Tbio 9,553 | 10,625
Tdark 4,558 | 7,003
Tchem 1,680 | 1,890
Tclin 509 | 602

Collection

Kinase: IDG Consortium (Targets) 114 | 125
Ion Channel: IDG Consortium (Targets) 79 | 102
GPCR: IDG Consortium (Targets) 67 | 128
Kinase: IDG Consortium (Complete/Control) 33 | 37
GPCR: IDG Consortium (Complete/Control) 20 | 24

IMPC Phenotype

preweaning lethality, complete... 614 | 633
preweaning lethality, incomple... 247 | 260
abnormal behavior 221 | 226
decreased lean body mass 188 | 195
embryonic lethality prior to t... 183 | 187
decreased total body fat amoun... 177 | 186
decreased body weight 167 | 174
decreased bone mineral content 151 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 125 | 131
increased or absent threshold ... 122 | 128
decreased bone mineral density 120 | 126
increased circulating alkaline... 118 | 119
decreased grip strength 114 | 123
decreased circulating glucose ... 109 | 121
decreased body length 107 | 108
abnormal embryo size 105 | 112
hyperactivity 103 | 108
enlarged heart 102 | 111
increased lean body mass 100 | 107
abnormal retina morphology 95 | 100
increased bone mineral content 90 | 92
increased mean corpuscular hem... 89 | 93
increased mean corpuscular vol... 88 | 91
hypoactivity 84 | 89
decreased circulating choleste... 82 | 85
short tibia 79 | 82
decreased circulating triglyce... 76 | 83
increased grip strength 76 | 83
decreased circulating HDL chol... 75 | 77
decreased circulating serum al... 74 | 79
abnormal lens morphology 72 | 73
decreased circulating insulin ... 67 | 75
increased fasted circulating g... 64 | 68
increased circulating sodium l... 63 | 71
prenatal lethality prior to he... 61 | 64
male infertility 59 | 62
abnormal sleep behavior 58 | 63
decreased lumbar vertebrae num... 58 | 62
increased circulating HDL chol... 58 | 63
abnormal retinal pigmentation 57 | 61
increased sacral vertebrae num... 57 | 62
abnormal bone mineralization 54 | 55
decreased rib number 54 | 59
increased total body fat amoun... 53 | 57
abnormal coat-hair pigmentatio... 51 | 54
decreased prepulse inhibition 51 | 52
decreased leukocyte cell numbe... 50 | 54
increased circulating choleste... 50 | 53
increased exploration in new e... 50 | 56
decreased mean corpuscular vol... 49 | 50
increased bone mineral density 49 | 52
decreased hemoglobin content 48 | 53
impaired glucose tolerance 48 | 52
improved glucose tolerance 48 | 56
abnormal behavioral response t... 47 | 52
abnormal gait 46 | 51
decreased circulating alanine ... 46 | 53
decreased startle reflex 46 | 48
decreased caudal vertebrae num... 45 | 49
decreased fasted circulating g... 45 | 49
abnormal heart morphology 44 | 51
thrombocytopenia 43 | 46
decreased erythrocyte cell num... 42 | 43
increased body weight 42 | 42
increased hemoglobin content 42 | 45
decreased circulating total pr... 41 | 41
increased blood urea nitrogen ... 41 | 44
decreased heart weight 40 | 44
decreased circulating alkaline... 38 | 41
increased rib number 38 | 41
decreased neutrophil cell numb... 37 | 37
increased circulating chloride... 37 | 43
abnormal eye morphology 36 | 38
abnormal seminal vesicle morph... 36 | 47
increased startle reflex 36 | 38
abnormal neural tube closure 35 | 37
decreased circulating LDL chol... 35 | 37
decreased eosinophil cell numb... 35 | 41
small testis 35 | 37
cardiovascular system phenotyp... 34 | 35
decreased circulating free fat... 34 | 39
increased hematocrit 34 | 36
increased leukocyte cell numbe... 34 | 37
decreased mean corpuscular hem... 33 | 34
tremors 33 | 34
abnormal spleen morphology 32 | 36
abnormal cranium morphology 31 | 32
increased heart weight 31 | 37
limb grasping 31 | 35
decreased T cell number 30 | 31
decreased blood urea nitrogen ... 30 | 31
decreased circulating calcium ... 30 | 33
decreased circulating fructosa... 30 | 31
decreased circulating chloride... 29 | 32
decreased threshold for audito... 29 | 32
female infertility 29 | 34
increased circulating calcium ... 29 | 32
increased circulating potassiu... 29 | 31
abnormal testis morphology 28 | 30

Disease

ovarian cancer 8,046 | 8,491
osteosarcoma 7,364 | 7,933
medulloblastoma, large-cell 5,778 | 6,234
psoriasis 5,775 | 6,685
glioblastoma 5,227 | 5,572
lung cancer 4,263 | 4,473
atypical teratoid / rhabdoid tumor 4,073 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,132 | 3,289
malignant mesothelioma 3,056 | 3,163
Breast cancer 2,947 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 2,847 | 2,988
pilocytic astrocytoma 2,835 | 3,086
invasive ductal carcinoma 2,821 | 2,950
primitive neuroectodermal tumor 2,815 | 3,031
intraductal papillary-mucinous adenoma (IPMA) 2,813 | 2,956
non-small cell lung cancer 2,649 | 2,798
oligodendroglioma 2,639 | 2,849
lung carcinoma 2,599 | 2,844
pediatric high grade glioma 2,526 | 2,712
lung adenocarcinoma 2,521 | 2,714
ependymoma 2,357 | 2,514
pancreatic cancer 2,169 | 2,300
subependymal giant cell astrocytoma 2,154 | 2,287
Cancer 2,138 | 2,346
interstitial cystitis 2,123 | 2,299
group 3 medulloblastoma 2,107 | 2,254
astrocytic glioma 2,091 | 2,241
ulcerative colitis 1,961 | 2,087
adult high grade glioma 1,948 | 2,148
Carcinoma 1,912 | 2,147
pituitary cancer 1,807 | 1,972
Pick disease 1,786 | 1,893
group 4 medulloblastoma 1,782 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,705 | 1,795
ductal carcinoma in situ 1,659 | 1,745
cystic fibrosis 1,576 | 1,670
breast carcinoma 1,524 | 1,614
tuberculosis 1,476 | 1,563
astrocytoma 1,430 | 1,493
medulloblastoma 1,407 | 1,524
posterior fossa group B ependymoma 1,394 | 1,530
colon cancer 1,393 | 1,475
posterior fossa group A ependymoma 1,382 | 1,511
sonic hedgehog group medulloblastoma 1,377 | 1,482
adrenocortical carcinoma 1,364 | 1,427
diabetes mellitus 1,350 | 1,663
Multiple myeloma 1,292 | 1,327
primary pancreatic ductal adenocarcinoma 1,230 | 1,271
juvenile dermatomyositis 1,159 | 1,189
acute quadriplegic myopathy 1,121 | 1,157
Rheumatoid Arthritis 1,100 | 1,170
atypical teratoid/rhabdoid tumor 1,024 | 1,095
spina bifida 1,008 | 1,064
cutaneous lupus erythematosus 962 | 1,056
nasopharyngeal carcinoma 961 | 1,056
dermatomyositis 950 | 966
active Crohn's disease 872 | 918
Atopic dermatitis 838 | 944
gastric carcinoma 792 | 832
non primary Sjogren syndrome sicca 764 | 840
acute myeloid leukemia 752 | 785
primary Sjogren syndrome 746 | 788
Waldenstrons macroglobulinemia 743 | 764
esophageal adenocarcinoma 691 | 737
tuberculosis and treatment for 6 months 665 | 686
progressive supranuclear palsy 645 | 674
aldosterone-producing adenoma 640 | 664
Alzheimer's disease 578 | 644
Duchenne muscular dystrophy 577 | 602
Intellectual disability 548 | 573
Obesity 540 | 616
pancreatic carcinoma 538 | 567
hepatocellular carcinoma 529 | 550
fibroadenoma 525 | 557
Down syndrome 518 | 548
Endometriosis 495 | 535
autosomal dominant Emery-Dreifuss muscular dystrophy 487 | 499
chronic rhinosinusitis 456 | 512
IGA Glomerulonephritis 442 | 454
active ulcerative colitis 442 | 477
Prostatic Neoplasms 440 | 471
mucosa-associated lymphoid tissue lymphoma 426 | 480
Multiple Sclerosis 424 | 498
Schizophrenia 421 | 503
gastric cancer 417 | 436
Amyotrophic Lateral Sclerosis 409 | 432
Mammary Neoplasms 386 | 410
inflammatory breast cancer 372 | 404
Neurodegenerative disease 364 | 383
non-small cell lung carcinoma 358 | 413
sarcoidosis 342 | 368
Kidney disease 331 | 397
Parkinson's disease 323 | 364
glioblastoma multiforme 319 | 347
Polycystic Ovary Syndrome 313 | 334
tuberculosis and treatment for 3 months 307 | 327
hereditary spastic paraplegia 305 | 313
nephrosclerosis 299 | 329
urothelial carcinoma 299 | 318
Epilepsy 298 | 346

Tissue

Nervous System 16,067 | 18,560
Female tissues 16,051 | 18,646
Digestive Tract 16,035 | 18,472
Endocrine System 16,028 | 18,511
Urinary Tract 15,983 | 18,443
Liver and Pancreas 15,937 | 18,135
Male tissues 15,918 | 17,968
Cardiovascular System 15,900 | 17,957
Blood and immune system 15,879 | 17,994
Skin and soft tissues 15,852 | 18,114
Respiratory system 15,670 | 17,483

Target Family

Non-IDG 9,489 | 11,969
Enzyme 3,682 | 4,146
Transcription Factor 1,259 | 1,400
Kinase 597 | 634
Transporter 407 | 473
GPCR 267 | 408
Ion Channel 263 | 341
Epigenetic 228 | 242
Nuclear Receptor 44 | 48
TF/Epigenetic 36 | 38
oGPCR 28 | 421

HCA RNA Cell Line

U-2197 16,300 | 16,300
U-2 OS 17,365 | 17,365
EFO-21 17,116 | 17,116
SCLC-21H 16,945 | 16,945
NTERA-2 16,845 | 16,845
U-266/70 16,555 | 16,555
BEWO 16,540 | 16,540
SH-SY5Y 16,520 | 16,520
HMC-1 16,393 | 16,393
NB-4 16,359 | 16,359
HaCaT 16,330 | 16,330
U-266/84 16,256 | 16,256
U-251 MG 16,194 | 16,194
U-87 MG 16,105 | 16,105
Karpas-707 16,093 | 16,093
U-698 16,092 | 16,092
WM-115 16,064 | 16,064
K-562 16,048 | 16,048
T-47d 16,036 | 16,036
U-937 15,987 | 15,987
AF22 15,978 | 15,978
SK-MEL-30 15,961 | 15,961
A-431 15,946 | 15,946
CAPAN-2 15,917 | 15,917
RPMI-8226 15,831 | 15,831
SK-BR-3 15,826 | 15,826
REH 15,782 | 15,782
U-138 MG 15,733 | 15,733
HEK 293 15,667 | 15,667
THP-1 15,651 | 15,651
MOLT-4 15,625 | 15,625
HDLM-2 15,578 | 15,578
Daudi 15,574 | 15,574
RH-30 15,519 | 15,519
HeLa 15,515 | 15,515
RT4 15,501 | 15,501
AN3-CA 15,462 | 15,462
BJ hTERT+ SV40 Large T+ 15,429 | 15,429
BJ hTERT+ SV40 Large T+ RasG12... 15,311 | 15,311
BJ 15,276 | 15,276
HTCEpi 15,271 | 15,271
CACO-2 15,254 | 15,254
PC-3 15,203 | 15,203
BJ hTERT+ 15,181 | 15,181
HEL 15,174 | 15,174
SiHa 15,106 | 15,106
RPTEC TERT1 15,101 | 15,101
MCF7 15,048 | 15,048
HBF TERT88 15,032 | 15,032
Hep G2 14,999 | 14,999
A549 14,994 | 14,994
HL-60 14,863 | 14,863
LHCN-M2 14,816 | 14,816
ASC TERT1 14,670 | 14,670
HUVEC TERT2 14,543 | 14,543
TIME 14,296 | 14,296

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.86495 767.9 361
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.50722 29.2 46
F-box/LRR-repeat protein 3 FBXL3 Tbio Non-IDG -0.94799 9.59 158
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.96873 85.2 108
Paralemmin-3 PALM3 Tbio Non-IDG -0.47712 3.44 66
Zinc finger protein Aiolos IKZF3 Tbio Transcription Factor -1.78743 55.0 277
Zinc finger protein 215 ZNF215 Tdark Transcription Factor -0.47111 3.15 74
Epithelial membrane protein 3 EMP3 Tbio Non-IDG -1.64647 44.8 131
UDP-glucuronosyltransferase 2B15 UGT2B15 Tchem Enzyme -1.77071 60.2 66