Development Level

Tbio 9,502 | 11,178
Tdark 3,792 | 6,569
Tchem 1,592 | 1,885
Tclin 460 | 612

Collection

Kinase: IDG Consortium (Target... 113 | 125
Ion Channel: IDG Consortium (T... 67 | 99
GPCR: IDG Consortium (Targets) 64 | 126
Kinase: IDG Consortium (Comple... 33 | 37
GPCR: IDG Consortium (Complete... 19 | 25

IMPC Phenotype

preweaning lethality, complete... 934 | 979
preweaning lethality, incomple... 449 | 499
embryonic lethality prior to t... 271 | 278
abnormal behavior 264 | 298
embryonic lethality prior to o... 235 | 239
abnormal embryo size 209 | 220
decreased total body fat amoun... 184 | 207
enlarged heart 177 | 210
decreased vertical activity 164 | 208
abnormal bone structure 162 | 187
increased lean body mass 154 | 172
decreased body weight 148 | 161
abnormal heart morphology 139 | 162
hyperactivity 131 | 148
decreased bone mineral content 125 | 151
decreased lean body mass 120 | 135
increased total body fat amoun... 118 | 134
decreased circulating glucose ... 112 | 126
hypoactivity 109 | 132
embryonic growth retardation 104 | 106
decreased bone mineral density 103 | 126
increased circulating alkaline... 103 | 122
increased startle reflex 103 | 112
decreased grip strength 99 | 116
male infertility 97 | 123
increased bone mineral content 95 | 108
abnormal seminal vesicle morph... 93 | 114
increased or absent threshold ... 91 | 101
increased mean corpuscular hem... 89 | 96
decreased body length 88 | 101
increased mean corpuscular vol... 86 | 92
short tibia 86 | 97
prenatal lethality prior to he... 85 | 87
cataract 82 | 92
decreased circulating choleste... 81 | 93
abnormal lens morphology 76 | 81
decreased prepulse inhibition 76 | 82
decreased mean corpuscular vol... 72 | 79
decreased circulating triglyce... 71 | 79
decreased lymphocyte cell numb... 69 | 83
increased fasted circulating g... 69 | 76
increased bone mineral density 68 | 72
decreased leukocyte cell numbe... 67 | 73
increased circulating HDL chol... 67 | 80
decreased circulating serum al... 65 | 82
impaired glucose tolerance 65 | 75
abnormal sleep behavior 64 | 70
abnormal eye morphology 63 | 68
abnormal retina morphology 63 | 71
decreased startle reflex 63 | 75
increased circulating sodium l... 63 | 71
decreased circulating HDL chol... 62 | 68
decreased hemoglobin content 61 | 68
small superior vagus ganglion 61 | 74
decreased circulating insulin ... 60 | 76
abnormal coat-hair pigmentatio... 59 | 64
abnormal gait 59 | 69
decreased erythrocyte cell num... 59 | 62
improved glucose tolerance 59 | 79
abnormal behavioral response t... 58 | 66
increased circulating choleste... 58 | 66
increased heart weight 57 | 62
abnormal kidney morphology 55 | 65
decreased fasted circulating g... 55 | 65
edema 54 | 59
increased monocyte cell number 52 | 63
thrombocytopenia 52 | 56
small testis 50 | 58
decreased caudal vertebrae num... 48 | 53
decreased mean corpuscular hem... 48 | 50
abnormal spleen morphology 46 | 55
decreased blood urea nitrogen ... 46 | 51
hydrometra 46 | 53
decreased circulating alanine ... 44 | 47
decreased hematocrit 44 | 46
female infertility 44 | 60
abnormal neural tube closure 43 | 46
decreased circulating total pr... 43 | 49
abnormal skin morphology 41 | 50
decreased circulating alkaline... 41 | 46
increased hematocrit 41 | 46
increased hemoglobin content 41 | 45
increased neutrophil cell numb... 41 | 46
increased blood urea nitrogen ... 40 | 48
increased leukocyte cell numbe... 39 | 47
increased mean platelet volume 39 | 45
decreased red blood cell distr... 38 | 41
decreased neutrophil cell numb... 37 | 42
increased circulating chloride... 37 | 41
tremors 37 | 39
abnormal bone mineralization 36 | 38
abnormal testis morphology 36 | 43
increased circulating triglyce... 36 | 42
increased erythrocyte cell num... 36 | 39
enlarged spleen 35 | 41
increased mean corpuscular hem... 35 | 36
limb grasping 35 | 41
decreased circulating LDL chol... 34 | 38
increased grip strength 34 | 41
prolonged QT interval 33 | 38

Disease

Carcinoma 9,128 | 11,192
ovarian cancer 7,580 | 8,297
osteosarcoma 7,048 | 7,766
medulloblastoma, large-cell 5,369 | 6,086
psoriasis 5,188 | 6,514
glioblastoma 5,041 | 5,635
atypical teratoid / rhabdoid tumor 4,432 | 4,971
lung cancer 4,129 | 4,607
ependymoma 3,961 | 4,559
group 3 medulloblastoma 3,538 | 4,002
adult high grade glioma 3,184 | 3,701
Breast cancer 3,041 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 2,855 | 3,204
malignant mesothelioma 2,843 | 3,135
primitive neuroectodermal tumor 2,611 | 2,957
Astrocytoma, Pilocytic 2,573 | 3,006
intraductal papillary-mucinous carcinoma (IPMC) 2,551 | 2,902
invasive ductal carcinoma 2,528 | 2,867
intraductal papillary-mucinous adenoma (IPMA) 2,499 | 2,872
non-small cell lung cancer 2,451 | 2,799
oligodendroglioma 2,402 | 2,768
lung carcinoma 2,294 | 2,755
lung adenocarcinoma 2,220 | 2,627
astrocytic glioma 2,216 | 2,530
Kidney cancer 2,138 | 2,548
pancreatic cancer 2,056 | 2,322
Cancer 2,048 | 2,388
subependymal giant cell astrocytoma 2,001 | 2,230
interstitial cystitis 1,858 | 2,237
pancreatic ductal adenocarcinoma liver metastasis 1,806 | 1,911
tuberculosis 1,792 | 1,963
Pick disease 1,683 | 1,856
group 4 medulloblastoma 1,613 | 1,806
pituitary cancer 1,608 | 1,915
ulcerative colitis 1,546 | 1,765
ductal carcinoma in situ 1,454 | 1,686
cystic fibrosis 1,357 | 1,629
breast carcinoma 1,350 | 1,589
diabetes mellitus 1,294 | 1,683
Multiple myeloma 1,270 | 1,296
adrenocortical carcinoma 1,266 | 1,385
Autosomal recessive predisposition 1,221 | 1,407
colon cancer 1,216 | 1,428
juvenile dermatomyositis 1,078 | 1,147
acute quadriplegic myopathy 1,068 | 1,133
Rheumatoid arthritis 1,053 | 1,156
astrocytoma 1,034 | 1,113
primary pancreatic ductal adenocarcinoma 968 | 1,071
spina bifida 961 | 1,053
pediatric high grade glioma 942 | 1,035
dermatomyositis 911 | 941
Schizophrenia 904 | 1,136
Intellectual disability 900 | 998
cutaneous lupus erythematosus 866 | 1,016
nasopharyngeal carcinoma 849 | 1,024
active Crohn's disease 772 | 882
non primary Sjogren syndrome sicca 754 | 861
acute myeloid leukemia 734 | 760
Waldenstrons macroglobulinemia 729 | 742
Atopic dermatitis 705 | 915
gastric carcinoma 687 | 781
Epilepsy 682 | 775
Liver Cirrhosis, Experimental 662 | 733
primary Sjogren syndrome 649 | 710
active ulcerative colitis 630 | 736
medulloblastoma 620 | 702
progressive supranuclear palsy 613 | 656
esophageal adenocarcinoma 603 | 696
aldosterone-producing adenoma 587 | 646
Dull intelligence 578 | 634
Low intelligence 578 | 634
Mental Retardation 578 | 634
Mental deficiency 578 | 634
Poor school performance 578 | 634
Cognitive delay 560 | 596
Global developmental delay 560 | 596
Mental and motor retardation 560 | 596
Alzheimer's disease 543 | 640
pancreatic carcinoma 532 | 555
Obesity 527 | 655
Seizures 521 | 584
Duchenne muscular dystrophy 520 | 587
Muscle hypotonia 519 | 562
Melanoma 513 | 689
hepatocellular carcinoma 513 | 536
Bipolar Disorder 488 | 646
Liver cancer 477 | 589
Short stature 471 | 514
autosomal dominant Emery-Dreifuss muscular dystrophy 446 | 492
Endometriosis 438 | 521
fibroadenoma 431 | 538
gastric cancer 422 | 445
Down syndrome 420 | 480
Prostatic Neoplasms 417 | 472
chronic rhinosinusitis 413 | 505
mucosa-associated lymphoid tissue lymphoma 406 | 473
Multiple Sclerosis 405 | 527
Amyotrophic lateral sclerosis 399 | 437
sonic hedgehog group medulloblastoma 395 | 459
tuberculosis and treatment for 6 months 393 | 399

Tissue

Endocrine System 15,084 | 18,159
Digestive Tract 14,904 | 17,369
Female tissues 14,899 | 17,400
Skin and soft tissues 14,871 | 17,230
Male tissues 14,776 | 17,142
Blood and immune system 14,767 | 16,909
Liver and Pancreas 14,678 | 16,750
Nervous System 14,648 | 16,725
Urinary Tract 14,629 | 16,678
Respiratory system 14,526 | 16,393
Cardiovascular System 13,816 | 15,192

Target Family

Non-IDG 8,915 | 12,091
Enzyme 3,546 | 4,145
Transcription Factor 1,142 | 1,400
Kinase 577 | 634
Transporter 371 | 473
Ion Channel 234 | 344
GPCR 233 | 408
Epigenetic 226 | 242
Nuclear Receptor 38 | 48
TF/Epigenetic 33 | 38
oGPCR 31 | 421

HCA RNA Cell Line

HEL 15,346 | 15,346
U-2 OS 17,559 | 17,559
EFO-21 17,301 | 17,301
SCLC-21H 17,139 | 17,139
NTERA-2 17,039 | 17,039
U-266/70 16,745 | 16,745
BEWO 16,726 | 16,726
SH-SY5Y 16,707 | 16,707
HMC-1 16,581 | 16,581
NB-4 16,547 | 16,547
HaCaT 16,515 | 16,515
U-2197 16,483 | 16,483
U-266/84 16,440 | 16,440
U-251 MG 16,365 | 16,365
U-87 MG 16,285 | 16,285
U-698 16,279 | 16,279
Karpas-707 16,275 | 16,275
WM-115 16,253 | 16,253
K-562 16,233 | 16,233
T-47d 16,213 | 16,213
U-937 16,180 | 16,180
AF22 16,160 | 16,160
SK-MEL-30 16,142 | 16,142
A-431 16,131 | 16,131
CAPAN-2 16,102 | 16,102
RPMI-8226 16,015 | 16,015
SK-BR-3 16,008 | 16,008
REH 15,960 | 15,960
U-138 MG 15,914 | 15,914
HEK 293 15,853 | 15,853
THP-1 15,833 | 15,833
MOLT-4 15,809 | 15,809
Daudi 15,753 | 15,753
HDLM-2 15,752 | 15,752
RH-30 15,693 | 15,693
HeLa 15,690 | 15,690
RT4 15,683 | 15,683
AN3-CA 15,648 | 15,648
BJ hTERT+ SV40 Large T+ 15,609 | 15,609
BJ hTERT+ SV40 Large T+ RasG12... 15,493 | 15,493
HTCEpi 15,453 | 15,453
BJ 15,448 | 15,448
CACO-2 15,436 | 15,436
PC-3 15,376 | 15,376
BJ hTERT+ 15,353 | 15,353
SiHa 15,286 | 15,286
RPTEC TERT1 15,278 | 15,278
MCF7 15,232 | 15,232
HBF TERT88 15,209 | 15,209
Hep G2 15,179 | 15,179
A549 15,174 | 15,174
HL-60 15,041 | 15,041
LHCN-M2 14,989 | 14,989
ASC TERT1 14,842 | 14,842
HUVEC TERT2 14,717 | 14,717
TIME 14,461 | 14,461

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15
DENN domain-containing protein 1A DENND1A Tbio Non-IDG -1.14835 13.7 90
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
Melanoma-associated antigen 9 MAGEA9B Tbio Non-IDG -1.32496 23.3 213
Melanoma-associated antigen 12 MAGEA12 Tbio Non-IDG -1.35716 21.7 116
General transcription factor IIE subunit 1 GTF2E1 Tbio Non-IDG 0.16 0.68 153
Neutral alpha-glucosidase C GANC Tchem Enzyme -1.74673 51.7 93
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.03938 994.7 101