Development Level

Tbio 9,199 | 10,625
Tdark 4,296 | 7,003
Tchem 1,620 | 1,890
Tclin 463 | 602

Collection

Kinase: IDG Consortium (Targets) 112 | 125
Ion Channel: IDG Consortium (Targets) 69 | 102
GPCR: IDG Consortium (Targets) 64 | 127
Kinase: IDG Consortium (Complete/Control) 33 | 37
GPCR: IDG Consortium (Complete/Control) 20 | 26

IMPC Phenotype

preweaning lethality, complete... 604 | 633
preweaning lethality, incomple... 234 | 260
abnormal behavior 211 | 226
embryonic lethality prior to t... 185 | 187
decreased lean body mass 179 | 195
decreased total body fat amoun... 178 | 186
decreased body weight 163 | 174
embryonic lethality prior to o... 148 | 148
decreased bone mineral content 141 | 157
abnormal bone structure 121 | 131
increased or absent threshold ... 117 | 128
decreased bone mineral density 116 | 126
increased circulating alkaline... 115 | 119
decreased grip strength 108 | 123
abnormal embryo size 105 | 112
decreased circulating glucose ... 105 | 121
decreased body length 104 | 108
hyperactivity 100 | 108
increased lean body mass 97 | 107
abnormal retina morphology 94 | 100
enlarged heart 92 | 111
increased mean corpuscular hem... 90 | 93
increased mean corpuscular vol... 87 | 91
increased bone mineral content 85 | 92
decreased circulating choleste... 82 | 85
hypoactivity 81 | 89
decreased circulating triglyce... 76 | 83
short tibia 75 | 82
decreased circulating HDL chol... 74 | 77
increased grip strength 72 | 83
decreased circulating serum al... 70 | 79
abnormal lens morphology 69 | 73
prenatal lethality prior to he... 64 | 64
increased circulating sodium l... 61 | 71
increased fasted circulating g... 61 | 68
abnormal retinal pigmentation 59 | 61
decreased lumbar vertebrae num... 58 | 62
increased sacral vertebrae num... 58 | 62
abnormal sleep behavior 57 | 63
decreased circulating insulin ... 57 | 75
decreased rib number 57 | 59
increased circulating HDL chol... 56 | 63
abnormal bone mineralization 55 | 55
male infertility 54 | 62
abnormal coat-hair pigmentatio... 51 | 54
decreased prepulse inhibition 51 | 52
increased circulating choleste... 51 | 53
increased total body fat amoun... 51 | 57
decreased leukocyte cell numbe... 50 | 54
increased bone mineral density 50 | 52
decreased hemoglobin content 49 | 53
decreased mean corpuscular vol... 49 | 50
impaired glucose tolerance 49 | 52
increased exploration in new e... 48 | 56
decreased circulating alanine ... 47 | 53
abnormal behavioral response t... 45 | 52
abnormal gait 45 | 51
decreased startle reflex 45 | 48
decreased caudal vertebrae num... 44 | 49
decreased fasted circulating g... 44 | 49
thrombocytopenia 44 | 46
improved glucose tolerance 43 | 56
abnormal heart morphology 42 | 51
decreased erythrocyte cell num... 42 | 43
increased blood urea nitrogen ... 41 | 44
increased hemoglobin content 41 | 45
decreased circulating alkaline... 39 | 41
increased body weight 39 | 42
increased circulating chloride... 39 | 43
decreased circulating total pr... 38 | 41
decreased eosinophil cell numb... 38 | 41
decreased heart weight 38 | 44
increased rib number 37 | 41
abnormal eye morphology 36 | 38
decreased circulating LDL chol... 35 | 37
increased leukocyte cell numbe... 35 | 37
abnormal neural tube closure 34 | 37
decreased circulating free fat... 34 | 39
decreased neutrophil cell numb... 34 | 37
increased heart weight 34 | 37
abnormal seminal vesicle morph... 33 | 47
tremors 33 | 34
abnormal cranium morphology 32 | 32
decreased mean corpuscular hem... 32 | 34
increased startle reflex 32 | 38
abnormal spleen morphology 31 | 36
decreased T cell number 31 | 31
increased hematocrit 31 | 36
small testis 31 | 37
decreased blood urea nitrogen ... 30 | 31
decreased circulating chloride... 30 | 32
increased circulating calcium ... 30 | 32
decreased circulating calcium ... 29 | 33
decreased circulating creatini... 29 | 31
decreased circulating fructosa... 29 | 31
limb grasping 29 | 35
cardiovascular system phenotyp... 28 | 35
decreased B cell number 28 | 30
increased circulating potassiu... 28 | 31
decreased NK T cell number 27 | 28

Disease

ovarian cancer 7,802 | 8,491
osteosarcoma 7,141 | 7,933
medulloblastoma, large-cell 5,554 | 6,234
psoriasis 5,453 | 6,685
glioblastoma 5,025 | 5,572
lung cancer 4,094 | 4,473
atypical teratoid / rhabdoid tumor 3,913 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 2,999 | 3,289
malignant mesothelioma 2,939 | 3,163
Breast cancer 2,805 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 2,706 | 2,988
primitive neuroectodermal tumor 2,696 | 3,031
pilocytic astrocytoma 2,681 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 2,673 | 2,956
invasive ductal carcinoma 2,660 | 2,950
oligodendroglioma 2,510 | 2,849
non-small cell lung cancer 2,496 | 2,798
lung carcinoma 2,433 | 2,844
pediatric high grade glioma 2,431 | 2,712
lung adenocarcinoma 2,348 | 2,714
ependymoma 2,269 | 2,514
pancreatic cancer 2,081 | 2,300
subependymal giant cell astrocytoma 2,071 | 2,287
Cancer 2,055 | 2,346
group 3 medulloblastoma 2,030 | 2,254
astrocytic glioma 1,986 | 2,241
interstitial cystitis 1,971 | 2,299
ulcerative colitis 1,868 | 2,087
adult high grade glioma 1,839 | 2,148
Carcinoma 1,764 | 2,147
Pick disease 1,730 | 1,893
pituitary cancer 1,710 | 1,972
group 4 medulloblastoma 1,706 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,660 | 1,795
ductal carcinoma in situ 1,559 | 1,745
cystic fibrosis 1,456 | 1,670
breast carcinoma 1,436 | 1,614
tuberculosis 1,414 | 1,563
astrocytoma 1,380 | 1,493
medulloblastoma 1,338 | 1,524
diabetes mellitus 1,329 | 1,663
sonic hedgehog group medulloblastoma 1,327 | 1,482
posterior fossa group A ependymoma 1,319 | 1,511
posterior fossa group B ependymoma 1,317 | 1,530
adrenocortical carcinoma 1,303 | 1,427
colon cancer 1,297 | 1,475
Multiple myeloma 1,294 | 1,327
primary pancreatic ductal adenocarcinoma 1,192 | 1,271
juvenile dermatomyositis 1,139 | 1,189
acute quadriplegic myopathy 1,100 | 1,157
Rheumatoid Arthritis 1,079 | 1,170
atypical teratoid/rhabdoid tumor 981 | 1,095
spina bifida 977 | 1,064
dermatomyositis 939 | 966
nasopharyngeal carcinoma 910 | 1,056
cutaneous lupus erythematosus 896 | 1,056
active Crohn's disease 815 | 918
Atopic dermatitis 769 | 944
gastric carcinoma 763 | 832
non primary Sjogren syndrome sicca 743 | 840
Waldenstrons macroglobulinemia 737 | 764
acute myeloid leukemia 733 | 785
primary Sjogren syndrome 720 | 788
tuberculosis and treatment for 6 months 659 | 686
esophageal adenocarcinoma 656 | 737
progressive supranuclear palsy 627 | 674
aldosterone-producing adenoma 608 | 664
Alzheimer's disease 550 | 644
Duchenne muscular dystrophy 547 | 602
Intellectual disability 524 | 573
Obesity 520 | 616
hepatocellular carcinoma 519 | 550
pancreatic carcinoma 516 | 567
Down syndrome 499 | 548
fibroadenoma 486 | 557
Endometriosis 468 | 535
autosomal dominant Emery-Dreifuss muscular dystrophy 467 | 499
chronic rhinosinusitis 433 | 512
IGA Glomerulonephritis 429 | 454
Prostatic Neoplasms 421 | 471
Multiple Sclerosis 411 | 498
active ulcerative colitis 408 | 477
mucosa-associated lymphoid tissue lymphoma 405 | 480
gastric cancer 399 | 436
Schizophrenia 394 | 503
Amyotrophic Lateral Sclerosis 392 | 432
Mammary Neoplasms 371 | 410
inflammatory breast cancer 354 | 404
Neurodegenerative disease 350 | 383
non-small cell lung carcinoma 335 | 413
sarcoidosis 329 | 368
Kidney disease 326 | 397
tuberculosis and treatment for 3 months 302 | 327
Polycystic Ovary Syndrome 299 | 334
glioblastoma multiforme 299 | 347
hereditary spastic paraplegia 298 | 313
Parkinson's disease 297 | 364
Asthma 281 | 349
urothelial carcinoma 279 | 318
nephrosclerosis 274 | 329

Tissue

Nervous System 15,358 | 18,560
Digestive Tract 15,332 | 18,472
Female tissues 15,330 | 18,646
Endocrine System 15,316 | 18,511
Urinary Tract 15,272 | 18,443
Liver and Pancreas 15,259 | 18,135
Blood and immune system 15,212 | 17,994
Cardiovascular System 15,211 | 17,957
Male tissues 15,207 | 17,968
Skin and soft tissues 15,169 | 18,114
Respiratory system 15,036 | 17,483

Target Family

Non-IDG 9,071 | 11,969
Enzyme 3,569 | 4,146
Transcription Factor 1,180 | 1,400
Kinase 579 | 634
Transporter 373 | 473
GPCR 246 | 408
Ion Channel 229 | 341
Epigenetic 223 | 242
Nuclear Receptor 47 | 48
TF/Epigenetic 36 | 38
oGPCR 25 | 421

HCA RNA Cell Line

HDLM-2 15,578 | 15,578
U-2 OS 17,365 | 17,365
EFO-21 17,116 | 17,116
SCLC-21H 16,945 | 16,945
NTERA-2 16,845 | 16,845
U-266/70 16,555 | 16,555
BEWO 16,540 | 16,540
SH-SY5Y 16,520 | 16,520
HMC-1 16,393 | 16,393
NB-4 16,359 | 16,359
HaCaT 16,330 | 16,330
U-2197 16,300 | 16,300
U-266/84 16,256 | 16,256
U-251 MG 16,194 | 16,194
U-87 MG 16,105 | 16,105
Karpas-707 16,093 | 16,093
U-698 16,092 | 16,092
WM-115 16,064 | 16,064
K-562 16,048 | 16,048
T-47d 16,036 | 16,036
U-937 15,987 | 15,987
AF22 15,978 | 15,978
SK-MEL-30 15,961 | 15,961
A-431 15,946 | 15,946
CAPAN-2 15,917 | 15,917
RPMI-8226 15,831 | 15,831
SK-BR-3 15,826 | 15,826
REH 15,782 | 15,782
U-138 MG 15,733 | 15,733
HEK 293 15,667 | 15,667
THP-1 15,651 | 15,651
MOLT-4 15,625 | 15,625
Daudi 15,574 | 15,574
RH-30 15,519 | 15,519
HeLa 15,515 | 15,515
RT4 15,501 | 15,501
AN3-CA 15,462 | 15,462
BJ hTERT+ SV40 Large T+ 15,429 | 15,429
BJ hTERT+ SV40 Large T+ RasG12... 15,311 | 15,311
BJ 15,276 | 15,276
HTCEpi 15,271 | 15,271
CACO-2 15,254 | 15,254
PC-3 15,203 | 15,203
BJ hTERT+ 15,181 | 15,181
HEL 15,174 | 15,174
SiHa 15,106 | 15,106
RPTEC TERT1 15,101 | 15,101
MCF7 15,048 | 15,048
HBF TERT88 15,032 | 15,032
Hep G2 14,999 | 14,999
A549 14,994 | 14,994
HL-60 14,863 | 14,863
LHCN-M2 14,816 | 14,816
ASC TERT1 14,670 | 14,670
HUVEC TERT2 14,543 | 14,543
TIME 14,296 | 14,296

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.86495 767.9 361
Interleukin-9 IL9 Tbio Non-IDG -2.46520 301.6 339
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.50722 29.2 46
F-box/LRR-repeat protein 3 FBXL3 Tbio Non-IDG -0.94799 9.59 158
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
Paralemmin-3 PALM3 Tbio Non-IDG -0.47712 3.44 66
Zinc finger protein Aiolos IKZF3 Tbio Transcription Factor -1.78743 55.0 277
Zinc finger protein 215 ZNF215 Tdark Transcription Factor -0.47111 3.15 74
Epithelial membrane protein 3 EMP3 Tbio Non-IDG -1.64647 44.8 131
UDP-glucuronosyltransferase 2B15 UGT2B15 Tchem Enzyme -1.77071 60.2 66