Development Level

Tbio 8 | 10,625

IMPC Term

absent pinna reflex 2 | 21
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating amylase ... 2 | 24
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
impaired righting response 2 | 19
increased circulating chloride... 2 | 43
increased circulating sodium l... 2 | 71
increased or absent threshold ... 2 | 128
stereotypic behavior 2 | 3
trunk curl 2 | 15
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal glucose homeostasis 1 | 5
abnormal locomotor activation 1 | 26
abnormal respiratory quotient 1 | 9
decreased body weight 1 | 174
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating potassiu... 1 | 17
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased NK T cell number 1 | 11
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased lean body mass 1 | 107
increased mean platelet volume 1 | 19
increased rib number 1 | 41
limb grasping 1 | 35
persistence of hyaloid vascula... 1 | 22

Disease

Nonsyndromic deafness 8 | 121
Sensorineural hearing loss 6 | 107
psoriasis 5 | 6,685
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
pituitary cancer 4 | 1,972
Breast cancer 3 | 3,094
Deafness 3 | 18
Usher syndrome 3 | 34
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
medulloblastoma, large-cell 3 | 6,234
osteosarcoma 3 | 7,933
ovarian cancer 3 | 8,484
pancreatic cancer 3 | 2,300
spina bifida 3 | 1,064
Blindness 2 | 84
Carcinoma 2 | 2,147
Hodgkin's lymphoma, nodular sclerosis 2 | 24
Neuropathy 2 | 210
Retinitis pigmentosa 2 | 153
adult high grade glioma 2 | 2,148
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 2,514
esophageal adenocarcinoma 2 | 737
facioscapulohumeral dystrophy 2 | 286
invasive ductal carcinoma 2 | 2,950
lung adenocarcinoma 2 | 2,713
lung cancer 2 | 4,466
lung carcinoma 2 | 2,844
medulloblastoma 2 | 1,524
pilocytic astrocytoma 2 | 3,086
sonic hedgehog group medulloblastoma 2 | 1,482
Ainhum 1 | 5
Atopic dermatitis 1 | 944
Bart-Pumphrey syndrome 1 | 4
Brain disease 1 | 83
Cancer 1 | 2,346
Cardiomyopathy 1 | 110
Cardiovascular system disease 1 | 194
Cellulitis 1 | 13
Clouston syndrome 1 | 9
DEAFNESS, AUTOSOMAL RECESSIVE 2 1 | 1
DEAFNESS, AUTOSOMAL RECESSIVE 6 1 | 1
DEAFNESS, AUTOSOMAL RECESSIVE 61 1 | 1
Deafness, Autosomal Dominant 11 1 | 1
Deafness, Autosomal Recessive 18 1 | 1
Deafness, Autosomal Recessive 37 1 | 1
Deafness, Autosomal Recessive 9 1 | 1
Deafness, Sensorineural, with Hypertrophic Cardiomyopathy 1 | 1
Deafness, autosomal dominant nonsyndromic sensorineural 22 1 | 1
Down syndrome 1 | 548
Enlarged vestibular aqueduct 1 | 10
Erythrokeratodermia variabilis 1 | 10
Glycerol kinase deficiency 1 | 10
Hepatitis 1 | 61
Hepatitis B 1 | 103
Hidradenitis suppurativa 1 | 12
Hypertension 1 | 287
Hypertensive disease 1 | 193
Ichthyoses 1 | 3
Keratitis 1 | 42
Keratosis 1 | 34
Leber congenital amaurosis 1 | 72
Liver Cirrhosis 1 | 101
Malignant neoplasm of prostate 1 | 67
Melanoma 1 | 261
Oculodentodigital dysplasia 1 | 14
Palmoplantar keratosis 1 | 36
Pick disease 1 | 1,893
Pneumoconiosis 1 | 14
Sensorineural Hearing Loss (disorder) 1 | 11
Skin Neoplasms 1 | 49
Stargardt disease 1 | 4
Substance-Related Disorders 1 | 114
Takayasu's arteritis 1 | 52
USHER SYNDROME, TYPE IB (disorder) 1 | 1
USHER SYNDROME, TYPE IC 1 | 1
Usher Syndrome, Type I 1 | 1
Usher Syndrome, Type II 1 | 4
Usher syndrome type 2 1 | 4
Usher syndrome, type 1B 1 | 1
Usher syndrome, type 1C 1 | 1
Vasculitis 1 | 64
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
adrenocortical carcinoma 1 | 1,427
breast carcinoma 1 | 1,614
colon cancer 1 | 1,475
cystic fibrosis 1 | 1,665
fibroadenoma 1 | 557
head and neck cancer 1 | 270
hepatocellular carcinoma 1 | 532
nasopharyngeal carcinoma 1 | 1,056
nephrosclerosis 1 | 329
non-small cell lung cancer 1 | 2,798
primary pancreatic ductal adenocarcinoma 1 | 1,271
progressive supranuclear palsy 1 | 674
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 1,557
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 8 | 17,995
Cardiovascular System 8 | 17,958
Digestive Tract 8 | 18,473
Endocrine System 8 | 18,512
Female tissues 8 | 18,647
Liver and Pancreas 8 | 18,136
Male tissues 8 | 17,969
Nervous System 8 | 18,561
Respiratory system 8 | 17,484
Skin and soft tissues 8 | 18,115
Urinary Tract 8 | 18,444

Target Family

Non-IDG 6 | 11,971
Enzyme 1 | 4,146
Transporter 1 | 473

Grant Application

5R21DC007183-02 8 | 8
3P41RR001209-23S1 157 | 157
5P41RR001209-22 157 | 157
5P41RR001209-23 157 | 157
2P51RR000165-51 139 | 139
5P51RR000163-52 136 | 136
5P51RR000163-51 132 | 132
5P51RR000165-50 130 | 130
2P51RR000163-50 128 | 128
5P51RR000164-48 127 | 127
5P51RR000164-50 125 | 125
5P51RR000164-49 112 | 112
5P51RR000165-49 106 | 106
5P41RR001646-19 103 | 103
5P41RR001646-20 103 | 103
7P51RR000163-41 100 | 100
2P41RR011823-16 99 | 99
5P51RR000163-42 98 | 98
5P51RR000163-43 98 | 98
5P41RR001081-24 94 | 94
5P41RR001646-18 90 | 90
5P41RR015301-09 82 | 82
5P51RR000167-49 78 | 78
5P41RR002250-26 65 | 65
5P51RR000168-40 65 | 65
5P51RR000168-41 65 | 65
5P41RR001646-27 64 | 64
5P51RR000165-40 63 | 63
5M01RR000188-45 60 | 60
3P41RR010888-05S1 59 | 59
5M01RR000030-40 58 | 58
5M01RR000096-39 57 | 57
5P41RR000954-25 57 | 57
5P41RR000954-26 57 | 57
2P41RR000954-33 56 | 56
5P41RR010888-14 56 | 56
5P41RR012408-13 55 | 55
5M01RR000188-46 53 | 53
5P41RR001646-28 52 | 52
5P51RR000167-48 52 | 52
5P51RR000168-49 52 | 52
5P41RR001646-29 51 | 51
2P41RR002250-25 50 | 50
5M01RR000188-47 50 | 50
5P51RR000166-39 47 | 47
5M01RR000043-40 46 | 46
5P51RR000168-50 46 | 46
5P41RR010888-15 45 | 45
5P41RR015301-08 45 | 45
5P41RR004050-13 44 | 44
5M01RR000847-37 43 | 43
5P41RR004050-12 43 | 43
5P51RR000167-50 43 | 43
5P51RR000169-50 43 | 43
5P41RR000954-34 42 | 42
2P41RR004050-21 41 | 41
5P41RR010888-13 41 | 41
5P51RR000168-48 41 | 41
5P51RR000167-40 40 | 40
5P41RR015301-07 39 | 39
5P51RR000164-39 39 | 39
5P51RR000168-39 39 | 39
2P51RR000169-49 38 | 38
5P51RR000169-48 38 | 38
5P41RR004050-23 37 | 37
5P51RR013986-13 37 | 37
3P51RR000167-46S2 36 | 36
5P41RR001008-25 36 | 36
5M01RR000043-49 35 | 35
5P20RR021905-04 35 | 35
5P41RR004050-22 35 | 35
5M01RR000040-40 34 | 34
5P20RR016481-10 34 | 34
5P41RR001315-19 34 | 34
3P60DE013079-01S1 32 | 32
5M01RR000833-26 32 | 32
5P20RR016481-11 32 | 32
5P20RR020152-07 32 | 32
5P41RR000862-38 32 | 32
5P51RR000166-49 32 | 32
5P60DE013079-02 32 | 32
5S06GM008037-29 32 | 32
5S06GM008037-30 32 | 32
5U41RR007707-10 32 | 32
2P20RR016480-09 31 | 31
5M01RR000827-34 31 | 31
5P41RR002250-24 31 | 31
5P41RR005959-22 31 | 31
5P41RR018522-08 31 | 31
3P60DE013079-03S1 30 | 30
5P20RR016457-10 30 | 30
5P41RR000592-40 30 | 30
5P41RR000592-41 30 | 30
5P41RR000862-36 30 | 30
5P41RR007707-17 30 | 30
5P51RR000166-48 30 | 30
5P60DE013079-03 30 | 30
5P60DE013079-04 30 | 30
5U54AI057168-09 30 | 30
5U54AI057168-10 30 | 30
2U54AI057168-06 29 | 29

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Harmonin USH1C Tbio Non-IDG -2.04033 115.8 173
Otoferlin OTOF Tbio Non-IDG -2.03900 115.9 40
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.12316 131.7 114
Unconventional myosin-VI MYO6 Tbio Non-IDG -1.63160 49.9 93
Transmembrane inner ear expressed protein TMIE Tbio Non-IDG -1.30378 21.0 55
Prestin SLC26A5 Tbio Transporter -3.05547 1204.1 90
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.14329 1444.2 196
Transmembrane protease serine 3 TMPRSS3 Tbio Enzyme -1.50481 35.5 200