Development Level

Tchem 6 | 1,890
Tbio 2 | 10,625
Tclin 1 | 602
Tdark 1 | 7,003

IMPC Term

increased circulating choleste... 2 | 53
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal lens morphology 1 | 73
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal startle reflex 1 | 14
cataract 1 | 26
decreased circulating fructosa... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating sodium l... 1 | 18
decreased fasted circulating g... 1 | 49
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 8 | 8,484
Cancer 7 | 2,346
glioblastoma 7 | 5,572
Vascular disease 5 | 281
astrocytoma 5 | 1,493
diabetes mellitus 5 | 1,663
osteosarcoma 5 | 7,933
Alzheimer's disease 4 | 644
Breast cancer 4 | 3,094
Carcinoma 4 | 2,147
Heart disease 4 | 279
Kidney disease 4 | 396
Mammary Neoplasms 4 | 410
Obesity 4 | 616
Parkinson's disease 4 | 364
Toxic encephalopathy 4 | 131
lung cancer 4 | 4,466
lung carcinoma 4 | 2,844
medulloblastoma, large-cell 4 | 6,234
pilocytic astrocytoma 4 | 3,086
Arthritis 3 | 248
Brain disease 3 | 83
Fatty liver disease 3 | 84
Hyperglycemia 3 | 120
Lung Neoplasms 3 | 171
Lung disease 3 | 132
Rheumatoid Arthritis 3 | 1,160
active Crohn's disease 3 | 918
acute quadriplegic myopathy 3 | 1,157
atypical teratoid / rhabdoid tumor 3 | 4,369
ependymoma 3 | 2,514
group 4 medulloblastoma 3 | 1,875
malignant mesothelioma 3 | 3,162
pancreatic cancer 3 | 2,300
psoriasis 3 | 6,685
Asthma 2 | 349
Brain Ischemia 2 | 87
Cardiomyopathies 2 | 90
Eye disease 2 | 55
Liver carcinoma 2 | 217
Liver disease 2 | 219
Liver neoplasms 2 | 109
Malignant neoplasm of breast 2 | 63
Metabolic syndrome X 2 | 155
Multiple myeloma 2 | 1,327
Neoplastic Cell Transformation 2 | 81
Osteoporosis 2 | 257
Reperfusion Injury 2 | 84
Schizophrenia 2 | 501
Stomach Neoplasms 2 | 282
acute myeloid leukemia 2 | 780
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
breast carcinoma 2 | 1,614
group 3 medulloblastoma 2 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
juvenile dermatomyositis 2 | 1,189
lung adenocarcinoma 2 | 2,713
non-small cell lung cancer 2 | 2,798
oligodendroglioma 2 | 2,849
pediatric high grade glioma 2 | 2,712
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,031
spina bifida 2 | 1,064
tuberculosis 2 | 1,557
46 XY gonadal dysgenesis 1 | 9
Cardiomyopathy 1 | 110
Chronic Lymphocytic Leukemia 1 | 242
Colorectal Neoplasms 1 | 217
Dengue disease 1 | 19
Diabetes Mellitus, Experimental 1 | 106
Drug-Induced Liver Injury 1 | 118
Encephalitis 1 | 54
Endocarditis 1 | 18
Fibrosis 1 | 40
Glioma 1 | 65
Gout 1 | 93
Hepatitis C 1 | 90
Hyperalgesia 1 | 71
Inflammation 1 | 109
Kidney Neoplasm 1 | 27
Liver Cirrhosis 1 | 101
Melanoma 1 | 261
Muscular atrophy 1 | 67
Pain agnosia 1 | 99
Parkinson Disease 1 | 102
Renal Cell Carcinoma 1 | 199
Retinal Degeneration 1 | 49
Skin cancer 1 | 37
Skin disease 1 | 65
Squamous cell carcinoma 1 | 94
Squamous cell carcinoma of esophagus 1 | 82
St. Louis encephalitis 1 | 5
Swyer Syndrome 1 | 8
active ulcerative colitis 1 | 477
facioscapulohumeral dystrophy 1 | 286
ovarian neoplasm 1 | 97
tick-borne encephalitis 1 | 14

Tissue

Blood and immune system 9 | 17,995
Cardiovascular System 9 | 17,958
Digestive Tract 9 | 18,473
Endocrine System 9 | 18,512
Female tissues 9 | 18,647
Liver and Pancreas 9 | 18,136
Male tissues 9 | 17,969
Nervous System 9 | 18,561
Respiratory system 9 | 17,484
Skin and soft tissues 9 | 18,115
Urinary Tract 9 | 18,444

Target Family

Kinase 6 | 634
Non-IDG 3 | 11,971
Transcription Factor 1 | 1,400

Grant Application

5R01DK067215-08 10 | 10
3P41RR001209-23S1 157 | 157
5P41RR001209-22 157 | 157
5P41RR001209-23 157 | 157
2P51RR000165-51 139 | 139
5P51RR000163-52 136 | 136
5P51RR000163-51 132 | 132
5P51RR000165-50 130 | 130
2P51RR000163-50 128 | 128
5P51RR000164-48 127 | 127
5P51RR000164-50 125 | 125
5P51RR000164-49 112 | 112
5P51RR000165-49 106 | 106
5P41RR001646-19 103 | 103
5P41RR001646-20 103 | 103
7P51RR000163-41 100 | 100
2P41RR011823-16 99 | 99
5P51RR000163-42 98 | 98
5P51RR000163-43 98 | 98
5P41RR001081-24 94 | 94
5P41RR001646-18 90 | 90
5P41RR015301-09 82 | 82
5P51RR000167-49 78 | 78
5P41RR002250-26 65 | 65
5P51RR000168-40 65 | 65
5P51RR000168-41 65 | 65
5P41RR001646-27 64 | 64
5P51RR000165-40 63 | 63
5M01RR000188-45 60 | 60
3P41RR010888-05S1 59 | 59
5M01RR000030-40 58 | 58
5M01RR000096-39 57 | 57
5P41RR000954-25 57 | 57
5P41RR000954-26 57 | 57
2P41RR000954-33 56 | 56
5P41RR010888-14 56 | 56
5P41RR012408-13 55 | 55
5M01RR000188-46 53 | 53
5P41RR001646-28 52 | 52
5P51RR000167-48 52 | 52
5P51RR000168-49 52 | 52
5P41RR001646-29 51 | 51
2P41RR002250-25 50 | 50
5M01RR000188-47 50 | 50
5P51RR000166-39 47 | 47
5M01RR000043-40 46 | 46
5P51RR000168-50 46 | 46
5P41RR010888-15 45 | 45
5P41RR015301-08 45 | 45
5P41RR004050-13 44 | 44
5M01RR000847-37 43 | 43
5P41RR004050-12 43 | 43
5P51RR000167-50 43 | 43
5P51RR000169-50 43 | 43
5P41RR000954-34 42 | 42
2P41RR004050-21 41 | 41
5P41RR010888-13 41 | 41
5P51RR000168-48 41 | 41
5P51RR000167-40 40 | 40
5P41RR015301-07 39 | 39
5P51RR000164-39 39 | 39
5P51RR000168-39 39 | 39
2P51RR000169-49 38 | 38
5P51RR000169-48 38 | 38
5P41RR004050-23 37 | 37
5P51RR013986-13 37 | 37
3P51RR000167-46S2 36 | 36
5P41RR001008-25 36 | 36
5M01RR000043-49 35 | 35
5P20RR021905-04 35 | 35
5P41RR004050-22 35 | 35
5M01RR000040-40 34 | 34
5P20RR016481-10 34 | 34
5P41RR001315-19 34 | 34
3P60DE013079-01S1 32 | 32
5M01RR000833-26 32 | 32
5P20RR016481-11 32 | 32
5P20RR020152-07 32 | 32
5P41RR000862-38 32 | 32
5P51RR000166-49 32 | 32
5P60DE013079-02 32 | 32
5S06GM008037-29 32 | 32
5S06GM008037-30 32 | 32
5U41RR007707-10 32 | 32
2P20RR016480-09 31 | 31
5M01RR000827-34 31 | 31
5P41RR002250-24 31 | 31
5P41RR005959-22 31 | 31
5P41RR018522-08 31 | 31
3P60DE013079-03S1 30 | 30
5P20RR016457-10 30 | 30
5P41RR000592-40 30 | 30
5P41RR000592-41 30 | 30
5P41RR000862-36 30 | 30
5P41RR007707-17 30 | 30
5P51RR000166-48 30 | 30
5P60DE013079-03 30 | 30
5P60DE013079-04 30 | 30
5U54AI057168-09 30 | 30
5U54AI057168-10 30 | 30
2U54AI057168-06 29 | 29

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
78 kDa glucose-regulated protein HSPA5 Tchem Non-IDG -3.28487 2003.3 918
Mitogen-activated protein kinase kinase kinase 5 MAP3K5 Tchem Kinase -2.58618 467.7 1104
SH3 domain-binding protein 5 SH3BP5 Tbio Non-IDG -2.70331 512.0 97
Putative cytochrome b-c1 complex subunit Rieske-like protein 1 UQCRFS1P1 Tdark Non-IDG -2.35159 224.9 0
Mitogen-activated protein kinase 8 MAPK8 Tchem Kinase -3.75582 5333.9 1016
Mitogen-activated protein kinase kinase kinase 11 MAP3K11 Tchem Kinase -1.81363 83.6 192
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.29533 18275.3 3137
Transcription factor AP-1 JUN Tchem Transcription Factor -3.80760 5981.8 2262
Mitogen-activated protein kinase kinase kinase 1 MAP3K1 Tbio Kinase -2.07309 110.8 261
RAF proto-oncogene serine/threonine-protein kinase RAF1 Tclin Kinase -3.07254 1147.5 1943