Development Level

Tchem 4 | 1,890
Tclin 4 | 602
Tbio 2 | 10,625

IMPC Phenotype

abnormal bone structure 1 | 131
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating phosphat... 1 | 15
decreased lean body mass 1 | 195
improved glucose tolerance 1 | 56
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased fasted circulating g... 1 | 68
increased total body fat amoun... 1 | 57
small kidney 1 | 10

Disease

ovarian cancer 7 | 8,491
Prostatic Neoplasms 6 | 471
Breast cancer 5 | 3,098
Cancer 5 | 2,346
Mammary Neoplasms 5 | 410
interstitial cystitis 5 | 2,299
psoriasis 5 | 6,685
Adenoma 4 | 165
Infertility 4 | 163
Male infertility 4 | 170
Polycystic Ovary Syndrome 4 | 334
adrenocortical carcinoma 4 | 1,427
lung cancer 4 | 4,473
pituitary cancer 4 | 1,972
Congenital adrenal hyperplasia 3 | 74
Cushing's syndrome 3 | 47
Endometriosis 3 | 535
Female infertility 3 | 28
Hyperandrogenism 3 | 32
Hypogonadism 3 | 70
Liver Cirrhosis, Experimental 3 | 108
Liver carcinoma 3 | 217
Lung Neoplasms 3 | 171
Peripheral Neuropathy 3 | 303
Premature ovarian failure 3 | 64
Prostate cancer 3 | 172
Pseudohermaphroditism 3 | 16
cystic fibrosis 3 | 1,670
ductal carcinoma in situ 3 | 1,745
lung adenocarcinoma 3 | 2,714
medulloblastoma, large-cell 3 | 6,234
osteosarcoma 3 | 7,933
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 1,563
Adenocarcinoma 2 | 115
Adrenal cortical adenoma 2 | 10
Alzheimer's disease 2 | 644
Amenorrhea 2 | 60
Anovulation 2 | 20
Antley-Bixler syndrome 2 | 15
Autoimmune polyendocrine syndrome 2 | 6
Balkan Nephropathy 2 | 6
Carcinoma of female breast 2 | 20
Cardiomegaly 2 | 66
Chronic Obstructive Airway Disease 2 | 47
Colorectal Neoplasms 2 | 217
Contact Dermatitis 2 | 80
Cryptorchidism 2 | 67
Endometrial Neoplasms 2 | 50
Endometrial cancer 2 | 32
Hypertension 2 | 293
Hypopituitarism 2 | 36
Hypospadias 2 | 65
Lung Injury 2 | 20
Obesity 2 | 616
Osteoporosis 2 | 259
Ovarian dysfunction 2 | 19
Precursor Cell Lymphoblastic Leukemia Lymphoma 2 | 42
Secondary malignant neoplasm of female breast 2 | 3
Squamous cell carcinoma 2 | 96
astrocytoma 2 | 1,493
atypical teratoid / rhabdoid tumor 2 | 4,369
glioblastoma 2 | 5,572
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
hepatocellular carcinoma 2 | 550
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
invasive ductal carcinoma 2 | 2,950
lung carcinoma 2 | 2,844
malignant mesothelioma 2 | 3,163
mucosa-associated lymphoid tissue lymphoma 2 | 480
non-small cell lung cancer 2 | 2,798
pancreatic cancer 2 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
posterior fossa group B ependymoma 2 | 1,530
primary Sjogren syndrome 2 | 788
primitive neuroectodermal tumor 2 | 3,031
substance-related disorder 2 | 104
ulcerative colitis 2 | 2,087
Acne vulgaris 1 | 16
Advanced Prostatic Carcinoma 1 | 5
Atrophic vulva 1 | 6
Breast disease 1 | 8
Breast fibroadenoma 1 | 8
Carcinosarcoma 1 | 6
Dyspareunia 1 | 3
Female hypogonadism syndrome 1 | 7
Infiltrating duct carcinoma of breast 1 | 4
Leiomyosarcoma 1 | 19
Lobular neoplasia 1 | 15
Menorrhagia 1 | 8
Metastatic Breast Cancer Progression Post-Antiestrogen Therapy 1 | 4
Ovulation induction 1 | 4
Premenstrual dysphoric disorder 1 | 8
Prevention of Breast Carcinoma 1 | 5
Prevention of Radiation-Induced Nausea and Vomiting 1 | 7
Primary ovarian failure 1 | 5
Retinoblastoma 1 | 14
Urethral atrophy 1 | 4

Tissue

Blood and immune system 10 | 17,994
Cardiovascular System 10 | 17,957
Digestive Tract 10 | 18,472
Endocrine System 10 | 18,511
Female tissues 10 | 18,646
Liver and Pancreas 10 | 18,135
Male tissues 10 | 17,968
Nervous System 10 | 18,560
Respiratory system 10 | 17,483
Skin and soft tissues 10 | 18,114
Urinary Tract 10 | 18,443

Target Family

Enzyme 5 | 4,146
Non-IDG 4 | 11,969
Nuclear Receptor 1 | 48

Grant Application

5R01DK060693-03 10 | 10
3P41RR001209-23S1 157 | 157
5P41RR001209-22 157 | 157
5P41RR001209-23 157 | 157
2P51RR000165-51 139 | 139
5P51RR000163-52 136 | 136
5P51RR000163-51 132 | 132
5P51RR000165-50 130 | 130
2P51RR000163-50 128 | 128
5P51RR000164-48 127 | 127
5P51RR000164-50 125 | 125
5P51RR000164-49 112 | 112
5P51RR000165-49 106 | 106
5P41RR001646-19 103 | 103
5P41RR001646-20 103 | 103
7P51RR000163-41 100 | 100
2P41RR011823-16 99 | 99
5P51RR000163-42 98 | 98
5P51RR000163-43 98 | 98
5P41RR001081-24 94 | 94
5P41RR001646-18 90 | 90
5P41RR015301-09 82 | 82
5P51RR000167-49 78 | 78
5P41RR002250-26 65 | 65
5P51RR000168-40 65 | 65
5P51RR000168-41 65 | 65
5P41RR001646-27 64 | 64
5P51RR000165-40 63 | 63
5M01RR000188-45 60 | 60
3P41RR010888-05S1 59 | 59
5M01RR000030-40 58 | 58
5M01RR000096-39 57 | 57
5P41RR000954-25 57 | 57
5P41RR000954-26 57 | 57
2P41RR000954-33 56 | 56
5P41RR010888-14 56 | 56
5P41RR012408-13 55 | 55
5M01RR000188-46 53 | 53
5P41RR001646-28 52 | 52
5P51RR000167-48 52 | 52
5P51RR000168-49 52 | 52
5P41RR001646-29 51 | 51
2P41RR002250-25 50 | 50
5M01RR000188-47 50 | 50
5P51RR000166-39 47 | 47
5M01RR000043-40 46 | 46
5P51RR000168-50 46 | 46
5P41RR010888-15 45 | 45
5P41RR015301-08 45 | 45
5P41RR004050-13 44 | 44
5M01RR000847-37 43 | 43
5P41RR004050-12 43 | 43
5P51RR000167-50 43 | 43
5P51RR000169-50 43 | 43
5P41RR000954-34 42 | 42
2P41RR004050-21 41 | 41
5P41RR010888-13 41 | 41
5P51RR000168-48 41 | 41
5P51RR000167-40 40 | 40
5P41RR015301-07 39 | 39
5P51RR000164-39 39 | 39
5P51RR000168-39 39 | 39
2P51RR000169-49 38 | 38
5P51RR000169-48 38 | 38
5P41RR004050-23 37 | 37
5P51RR013986-13 37 | 37
3P51RR000167-46S2 36 | 36
5P41RR001008-25 36 | 36
5M01RR000043-49 35 | 35
5P20RR021905-04 35 | 35
5P41RR004050-22 35 | 35
5M01RR000040-40 34 | 34
5P20RR016481-10 34 | 34
5P41RR001315-19 34 | 34
3P60DE013079-01S1 32 | 32
5M01RR000833-26 32 | 32
5P20RR016481-11 32 | 32
5P20RR020152-07 32 | 32
5P41RR000862-38 32 | 32
5P51RR000166-49 32 | 32
5P60DE013079-02 32 | 32
5S06GM008037-29 32 | 32
5S06GM008037-30 32 | 32
5U41RR007707-10 32 | 32
2P20RR016480-09 31 | 31
5M01RR000827-34 31 | 31
5P41RR002250-24 31 | 31
5P41RR005959-22 31 | 31
5P41RR018522-08 31 | 31
3P60DE013079-03S1 30 | 30
5P20RR016457-10 30 | 30
5P41RR000592-40 30 | 30
5P41RR000592-41 30 | 30
5P41RR000862-36 30 | 30
5P41RR007707-17 30 | 30
5P51RR000166-48 30 | 30
5P60DE013079-03 30 | 30
5P60DE013079-04 30 | 30
5U54AI057168-09 30 | 30
5U54AI057168-10 30 | 30
2U54AI057168-06 29 | 29

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome P450 1A1 CYP1A1 Tchem Non-IDG -3.53853 3553.5 340
Cytochrome P450 1A2 CYP1A2 Tchem Non-IDG -3.31421 2022.5 420
Aromatase CYP19A1 Tclin Enzyme -3.36046 2296.5 412
17-beta-hydroxysteroid dehydrogenase type 6 HSD17B6 Tbio Enzyme -3.06993 1098.8 74
Interferon-inducible protein AIM2 AIM2 Tbio Non-IDG -2.11585 140.7 401
Sulfotransferase 1A1 SULT1A1 Tchem Enzyme -2.46065 330.9 248
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.07458 1167.0 314
Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 Tclin Enzyme -2.91998 760.1 265
Cytochrome P450 1B1 CYP1B1 Tchem Non-IDG -2.91993 863.4 217
Estrogen receptor ESR1 Tclin Nuclear Receptor -3.98456 8119.2 2214