Development Level

Tbio 70 | 10,625
Tchem 37 | 1,890
Tclin 26 | 602
Tdark 3 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal behavior 4 | 226
decreased body weight 3 | 174
decreased grip strength 3 | 123
limb grasping 3 | 35
abnormal behavioral response t... 2 | 52
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
embryonic lethality prior to t... 2 | 187
hypoactivity 2 | 89
impaired pupillary reflex 2 | 14
increased circulating calcium ... 2 | 32
increased circulating chloride... 2 | 43
increased circulating sodium l... 2 | 71
increased monocyte cell number 2 | 27
increased or absent threshold ... 2 | 128
mydriasis 2 | 9
preweaning lethality, complete... 2 | 633
thrombocytopenia 2 | 46
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal lens morphology 1 | 73
abnormal liver morphology 1 | 5
abnormal optic disc morphology 1 | 10
abnormal sensory capabilities/... 1 | 3
abnormal sleep behavior 1 | 63
abnormal tail movements 1 | 12
abnormal vibrissa morphology 1 | 17
absent optic nerve 1 | 1
absent startle reflex 1 | 15
absent vibrissae 1 | 14
cataract 1 | 26
decreased CD8-positive, alpha-... 1 | 26
decreased IgE level 1 | 3
decreased NK T cell number 1 | 28
decreased alpha-beta T cell nu... 1 | 12
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating thyroxin... 1 | 5
decreased dendritic cell numbe... 1 | 3
decreased kidney weight 1 | 7
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean platelet volume 1 | 12
decreased vertical activity 1 | 22
enlarged lymph nodes 1 | 27
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased KLRG1-positive gamma... 1 | 2
increased T cell number 1 | 15
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased circulating alkaline... 1 | 119
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased effector memory CD8-... 1 | 14
increased effector memory T-he... 1 | 5
increased erythrocyte cell num... 1 | 26
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
increased myeloid cell number 1 | 2
increased sacral vertebrae num... 1 | 62
increased thoracic vertebrae n... 1 | 8
male infertility 1 | 62
premature death 1 | 5
preweaning lethality, incomple... 1 | 260
small adrenal glands 1 | 15
small testis 1 | 37
tremors 1 | 34
urinary bladder obstruction 1 | 2

Disease

Cancer 73 | 2,346
psoriasis 72 | 6,685
ovarian cancer 61 | 8,484
lung cancer 60 | 4,466
glioblastoma 53 | 5,572
osteosarcoma 50 | 7,933
Breast cancer 47 | 3,094
medulloblastoma, large-cell 44 | 6,234
pilocytic astrocytoma 39 | 3,086
interstitial cystitis 38 | 2,299
diabetes mellitus 37 | 1,663
invasive ductal carcinoma 37 | 2,950
atypical teratoid / rhabdoid tumor 36 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 36 | 3,289
lung carcinoma 36 | 2,844
malignant mesothelioma 36 | 3,162
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,956
pediatric high grade glioma 34 | 2,712
Obesity 33 | 616
non-small cell lung cancer 33 | 2,798
ulcerative colitis 33 | 2,087
lung adenocarcinoma 32 | 2,713
Alzheimer's disease 30 | 644
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,988
Carcinoma 29 | 2,147
Endometriosis 28 | 535
Hypertension 28 | 287
Asthma 27 | 349
pituitary cancer 27 | 1,972
Schizophrenia 26 | 501
pancreatic cancer 26 | 2,300
breast carcinoma 25 | 1,614
cutaneous lupus erythematosus 25 | 1,056
cystic fibrosis 25 | 1,665
oligodendroglioma 25 | 2,849
ductal carcinoma in situ 24 | 1,745
Autistic Disorder 23 | 320
primitive neuroectodermal tumor 23 | 3,031
Kidney disease 22 | 396
posterior fossa group A ependymoma 22 | 1,511
tuberculosis 22 | 1,557
Mammary Neoplasms 21 | 410
Prostatic Neoplasms 21 | 471
Rheumatoid Arthritis 21 | 1,160
colon cancer 21 | 1,475
group 3 medulloblastoma 20 | 2,254
Atherosclerosis 19 | 275
Cerebrovascular disease 19 | 231
Infertility 19 | 163
Parkinson's disease 19 | 364
astrocytic glioma 19 | 2,241
Arthritis 18 | 248
Atopic dermatitis 18 | 944
Inflammatory bowel disease 18 | 142
adult high grade glioma 18 | 2,148
Bipolar Disorder 17 | 266
Heart disease 17 | 279
Lung disease 17 | 132
ependymoma 17 | 2,514
Adenoma 16 | 165
Coronary artery disease 16 | 240
Dementia 16 | 129
Major Depressive Disorder 16 | 106
Pick disease 16 | 1,893
adrenocortical carcinoma 16 | 1,427
astrocytoma 16 | 1,493
subependymal giant cell astrocytoma 16 | 2,287
Hyperglycemia 15 | 120
Hypersensitivity reaction type II disease 15 | 235
Inflammation 15 | 109
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
posterior fossa group B ependymoma 15 | 1,530
Diarrhea 14 | 155
Hypertensive disease 14 | 193
Metabolic syndrome X 14 | 155
Multiple Sclerosis 14 | 498
Polycystic Ovary Syndrome 14 | 332
Toxic encephalopathy 14 | 131
medulloblastoma 14 | 1,524
Alcohol dependence 13 | 107
Hypogonadism 13 | 70
Liver carcinoma 13 | 217
Osteoporosis 13 | 257
Stomach Neoplasms 13 | 282
Vascular disease 13 | 281
Cocaine-Related Disorders 12 | 88
Depressive disorder 12 | 48
Liver disease 12 | 219
Neoplasm Metastasis 12 | 138
Seizures 12 | 95
atypical teratoid/rhabdoid tumor 12 | 1,095
non-small cell lung carcinoma 12 | 413
sarcoidosis 12 | 358
Allergic hypersensitivity disease 11 | 123
Epilepsy 11 | 346
Neurodegenerative disease 11 | 383
active Crohn's disease 11 | 918
gastric carcinoma 11 | 832
hepatocellular carcinoma 11 | 532
pancreatic carcinoma 11 | 567

Tissue

Nervous System 135 | 18,561
Female tissues 134 | 18,647
Digestive Tract 133 | 18,473
Endocrine System 133 | 18,512
Skin and soft tissues 132 | 18,115
Urinary Tract 132 | 18,444
Cardiovascular System 131 | 17,958
Liver and Pancreas 131 | 18,136
Male tissues 129 | 17,969
Blood and immune system 127 | 17,995
Respiratory system 125 | 17,484

Target Family

Non-IDG 73 | 11,971
Enzyme 25 | 4,146
GPCR 14 | 406
Transcription Factor 7 | 1,400
Kinase 5 | 634
Nuclear Receptor 5 | 48
Ion Channel 3 | 341
Transporter 3 | 473
TF/Epigenetic 1 | 38

Grant Application

5P51RR000163-52 136 | 136
3P41RR001209-23S1 157 | 157
5P41RR001209-22 157 | 157
5P41RR001209-23 157 | 157
2P51RR000165-51 139 | 139
5P51RR000163-51 132 | 132
5P51RR000165-50 130 | 130
2P51RR000163-50 128 | 128
5P51RR000164-48 127 | 127
5P51RR000164-50 125 | 125
5P51RR000164-49 112 | 112
5P51RR000165-49 106 | 106
5P41RR001646-19 103 | 103
5P41RR001646-20 103 | 103
7P51RR000163-41 100 | 100
2P41RR011823-16 99 | 99
5P51RR000163-42 98 | 98
5P51RR000163-43 98 | 98
5P41RR001081-24 94 | 94
5P41RR001646-18 90 | 90
5P41RR015301-09 82 | 82
5P51RR000167-49 78 | 78
5P41RR002250-26 65 | 65
5P51RR000168-40 65 | 65
5P51RR000168-41 65 | 65
5P41RR001646-27 64 | 64
5P51RR000165-40 63 | 63
5M01RR000188-45 60 | 60
3P41RR010888-05S1 59 | 59
5M01RR000030-40 58 | 58
5M01RR000096-39 57 | 57
5P41RR000954-25 57 | 57
5P41RR000954-26 57 | 57
2P41RR000954-33 56 | 56
5P41RR010888-14 56 | 56
5P41RR012408-13 55 | 55
5M01RR000188-46 53 | 53
5P41RR001646-28 52 | 52
5P51RR000167-48 52 | 52
5P51RR000168-49 52 | 52
5P41RR001646-29 51 | 51
2P41RR002250-25 50 | 50
5M01RR000188-47 50 | 50
5P51RR000166-39 47 | 47
5M01RR000043-40 46 | 46
5P51RR000168-50 46 | 46
5P41RR010888-15 45 | 45
5P41RR015301-08 45 | 45
5P41RR004050-13 44 | 44
5M01RR000847-37 43 | 43
5P41RR004050-12 43 | 43
5P51RR000167-50 43 | 43
5P51RR000169-50 43 | 43
5P41RR000954-34 42 | 42
2P41RR004050-21 41 | 41
5P41RR010888-13 41 | 41
5P51RR000168-48 41 | 41
5P51RR000167-40 40 | 40
5P41RR015301-07 39 | 39
5P51RR000164-39 39 | 39
5P51RR000168-39 39 | 39
2P51RR000169-49 38 | 38
5P51RR000169-48 38 | 38
5P41RR004050-23 37 | 37
5P51RR013986-13 37 | 37
3P51RR000167-46S2 36 | 36
5P41RR001008-25 36 | 36
5M01RR000043-49 35 | 35
5P20RR021905-04 35 | 35
5P41RR004050-22 35 | 35
5M01RR000040-40 34 | 34
5P20RR016481-10 34 | 34
5P41RR001315-19 34 | 34
3P60DE013079-01S1 32 | 32
5M01RR000833-26 32 | 32
5P20RR016481-11 32 | 32
5P20RR020152-07 32 | 32
5P41RR000862-38 32 | 32
5P51RR000166-49 32 | 32
5P60DE013079-02 32 | 32
5S06GM008037-29 32 | 32
5S06GM008037-30 32 | 32
5U41RR007707-10 32 | 32
2P20RR016480-09 31 | 31
5M01RR000827-34 31 | 31
5P41RR002250-24 31 | 31
5P41RR005959-22 31 | 31
5P41RR018522-08 31 | 31
3P60DE013079-03S1 30 | 30
5P20RR016457-10 30 | 30
5P41RR000592-40 30 | 30
5P41RR000592-41 30 | 30
5P41RR000862-36 30 | 30
5P41RR007707-17 30 | 30
5P51RR000166-48 30 | 30
5P60DE013079-03 30 | 30
5P60DE013079-04 30 | 30
5U54AI057168-09 30 | 30
5U54AI057168-10 30 | 30
2U54AI057168-06 29 | 29

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.34520 2413.2 212
Coagulation factor XI F11 Tchem Enzyme -2.65863 487.3 216
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Interleukin-15 IL15 Tbio Non-IDG -3.01964 1248.2 612
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Toll-like receptor 7 TLR7 Tclin Non-IDG -2.92878 974.2 670
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.11277 1238.0 122
Alpha-synuclein SNCA Tchem Non-IDG -3.59982 3997.3 1484