Development Level

Tbio 68 | 10,625
Tchem 35 | 1,890
Tclin 26 | 602
Tdark 3 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 6 | 633
abnormal behavior 3 | 226
abnormal bone structure 3 | 131
decreased bone mineral content 3 | 157
decreased grip strength 3 | 123
decreased lean body mass 3 | 195
limb grasping 3 | 35
abnormal behavioral response t... 2 | 52
abnormal lens morphology 2 | 73
abnormal sleep behavior 2 | 63
cataract 2 | 26
decreased body weight 2 | 174
embryonic lethality prior to t... 2 | 187
hyperactivity 2 | 108
hypoactivity 2 | 89
impaired pupillary reflex 2 | 14
increased circulating alkaline... 2 | 119
increased circulating calcium ... 2 | 32
increased erythrocyte cell num... 2 | 26
increased grip strength 2 | 83
increased monocyte cell number 2 | 27
mydriasis 2 | 9
abnormal coat appearance 1 | 25
abnormal coping response 1 | 12
abnormal embryo size 1 | 112
abnormal liver morphology 1 | 5
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sensory capabilities/... 1 | 3
absent startle reflex 1 | 15
absent vibrissae 1 | 14
decreased CD8-positive, alpha-... 1 | 26
decreased IgE level 1 | 3
decreased NK T cell number 1 | 28
decreased alpha-beta T cell nu... 1 | 12
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating thyroxin... 1 | 5
decreased dendritic cell numbe... 1 | 3
decreased kidney weight 1 | 7
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
enlarged lymph nodes 1 | 27
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased KLRG1-positive gamma... 1 | 2
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased effector memory CD8-... 1 | 14
increased effector memory T-he... 1 | 5
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased myeloid cell number 1 | 2
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased sacral vertebrae num... 1 | 62
increased thoracic vertebrae n... 1 | 8
male infertility 1 | 62
premature death 1 | 5
preweaning lethality, incomple... 1 | 260
small adrenal glands 1 | 15
small testis 1 | 37
sparse hair 1 | 6
thrombocytosis 1 | 23
urinary bladder obstruction 1 | 2

Disease

Cancer 79 | 2,346
psoriasis 78 | 6,685
ovarian cancer 63 | 8,484
lung cancer 59 | 4,466
osteosarcoma 58 | 7,933
glioblastoma 54 | 5,572
medulloblastoma, large-cell 45 | 6,234
diabetes mellitus 43 | 1,663
malignant mesothelioma 42 | 3,162
Breast cancer 38 | 3,094
atypical teratoid / rhabdoid tumor 38 | 4,369
lung carcinoma 38 | 2,844
pilocytic astrocytoma 37 | 3,086
invasive ductal carcinoma 36 | 2,950
Carcinoma 34 | 2,147
cystic fibrosis 32 | 1,665
interstitial cystitis 32 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,956
pancreatic cancer 31 | 2,300
ulcerative colitis 31 | 2,087
Obesity 30 | 616
tuberculosis 30 | 1,557
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,289
lung adenocarcinoma 29 | 2,713
pediatric high grade glioma 29 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,988
Alzheimer's disease 27 | 644
Kidney disease 27 | 396
pituitary cancer 27 | 1,972
Asthma 26 | 349
Rheumatoid Arthritis 26 | 1,160
non-small cell lung cancer 26 | 2,798
Hypertension 25 | 287
oligodendroglioma 24 | 2,849
Endometriosis 23 | 535
Atherosclerosis 21 | 275
cutaneous lupus erythematosus 21 | 1,056
Inflammatory bowel disease 20 | 142
Schizophrenia 20 | 501
breast carcinoma 20 | 1,614
ductal carcinoma in situ 20 | 1,745
primitive neuroectodermal tumor 20 | 3,031
Arthritis 19 | 248
Cerebrovascular disease 19 | 231
Coronary artery disease 19 | 240
Heart disease 19 | 279
Mammary Neoplasms 19 | 410
Prostatic Neoplasms 19 | 471
adult high grade glioma 19 | 2,148
subependymal giant cell astrocytoma 19 | 2,287
Infertility 18 | 163
Lung disease 18 | 132
Multiple Sclerosis 18 | 498
Parkinson's disease 18 | 364
adrenocortical carcinoma 18 | 1,427
colon cancer 18 | 1,475
Atopic dermatitis 17 | 944
Autistic Disorder 17 | 320
Hypersensitivity reaction type II disease 17 | 235
Pick disease 17 | 1,893
astrocytoma 17 | 1,493
posterior fossa group A ependymoma 17 | 1,511
Diarrhea 16 | 155
Inflammation 16 | 109
astrocytic glioma 16 | 2,241
ependymoma 16 | 2,514
group 4 medulloblastoma 16 | 1,875
sarcoidosis 16 | 358
Adenoma 15 | 165
Hyperglycemia 15 | 120
Liver disease 15 | 219
Metabolic syndrome X 15 | 155
Neoplasm Metastasis 15 | 138
Polycystic Ovary Syndrome 15 | 332
posterior fossa group B ependymoma 15 | 1,530
Allergic hypersensitivity disease 14 | 123
Bipolar Disorder 14 | 266
Dementia 14 | 129
Vascular disease 14 | 281
group 3 medulloblastoma 14 | 2,254
juvenile dermatomyositis 14 | 1,189
Major Depressive Disorder 13 | 106
Osteoporosis 13 | 257
acute quadriplegic myopathy 13 | 1,157
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
Brain disease 12 | 83
Dermatitis 12 | 107
Epilepsy 12 | 346
Hypertensive disease 12 | 193
Influenza 12 | 142
Multiple myeloma 12 | 1,327
Peripheral Neuropathy 12 | 303
Seizures 12 | 95
Stomach Neoplasms 12 | 282
Toxic encephalopathy 12 | 131
active Crohn's disease 12 | 918
dermatomyositis 12 | 933
medulloblastoma 12 | 1,524
primary Sjogren syndrome 12 | 789
primary pancreatic ductal adenocarcinoma 12 | 1,271

Tissue

Nervous System 132 | 18,561
Digestive Tract 130 | 18,473
Female tissues 130 | 18,647
Urinary Tract 130 | 18,444
Cardiovascular System 129 | 17,958
Endocrine System 129 | 18,512
Skin and soft tissues 129 | 18,115
Liver and Pancreas 128 | 18,136
Male tissues 128 | 17,969
Blood and immune system 125 | 17,995
Respiratory system 123 | 17,484

Target Family

Non-IDG 79 | 11,971
Enzyme 17 | 4,146
GPCR 14 | 406
Transporter 7 | 473
Kinase 5 | 634
Ion Channel 3 | 341
Nuclear Receptor 3 | 48
Transcription Factor 3 | 1,400
Epigenetic 1 | 242

Grant Application

5P51RR000163-51 132 | 132
3P41RR001209-23S1 157 | 157
5P41RR001209-22 157 | 157
5P41RR001209-23 157 | 157
2P51RR000165-51 139 | 139
5P51RR000163-52 136 | 136
5P51RR000165-50 130 | 130
2P51RR000163-50 128 | 128
5P51RR000164-48 127 | 127
5P51RR000164-50 125 | 125
5P51RR000164-49 112 | 112
5P51RR000165-49 106 | 106
5P41RR001646-19 103 | 103
5P41RR001646-20 103 | 103
7P51RR000163-41 100 | 100
2P41RR011823-16 99 | 99
5P51RR000163-42 98 | 98
5P51RR000163-43 98 | 98
5P41RR001081-24 94 | 94
5P41RR001646-18 90 | 90
5P41RR015301-09 82 | 82
5P51RR000167-49 78 | 78
5P41RR002250-26 65 | 65
5P51RR000168-40 65 | 65
5P51RR000168-41 65 | 65
5P41RR001646-27 64 | 64
5P51RR000165-40 63 | 63
5M01RR000188-45 60 | 60
3P41RR010888-05S1 59 | 59
5M01RR000030-40 58 | 58
5M01RR000096-39 57 | 57
5P41RR000954-25 57 | 57
5P41RR000954-26 57 | 57
2P41RR000954-33 56 | 56
5P41RR010888-14 56 | 56
5P41RR012408-13 55 | 55
5M01RR000188-46 53 | 53
5P41RR001646-28 52 | 52
5P51RR000167-48 52 | 52
5P51RR000168-49 52 | 52
5P41RR001646-29 51 | 51
2P41RR002250-25 50 | 50
5M01RR000188-47 50 | 50
5P51RR000166-39 47 | 47
5M01RR000043-40 46 | 46
5P51RR000168-50 46 | 46
5P41RR010888-15 45 | 45
5P41RR015301-08 45 | 45
5P41RR004050-13 44 | 44
5M01RR000847-37 43 | 43
5P41RR004050-12 43 | 43
5P51RR000167-50 43 | 43
5P51RR000169-50 43 | 43
5P41RR000954-34 42 | 42
2P41RR004050-21 41 | 41
5P41RR010888-13 41 | 41
5P51RR000168-48 41 | 41
5P51RR000167-40 40 | 40
5P41RR015301-07 39 | 39
5P51RR000164-39 39 | 39
5P51RR000168-39 39 | 39
2P51RR000169-49 38 | 38
5P51RR000169-48 38 | 38
5P41RR004050-23 37 | 37
5P51RR013986-13 37 | 37
3P51RR000167-46S2 36 | 36
5P41RR001008-25 36 | 36
5M01RR000043-49 35 | 35
5P20RR021905-04 35 | 35
5P41RR004050-22 35 | 35
5M01RR000040-40 34 | 34
5P20RR016481-10 34 | 34
5P41RR001315-19 34 | 34
3P60DE013079-01S1 32 | 32
5M01RR000833-26 32 | 32
5P20RR016481-11 32 | 32
5P20RR020152-07 32 | 32
5P41RR000862-38 32 | 32
5P51RR000166-49 32 | 32
5P60DE013079-02 32 | 32
5S06GM008037-29 32 | 32
5S06GM008037-30 32 | 32
5U41RR007707-10 32 | 32
2P20RR016480-09 31 | 31
5M01RR000827-34 31 | 31
5P41RR002250-24 31 | 31
5P41RR005959-22 31 | 31
5P41RR018522-08 31 | 31
3P60DE013079-03S1 30 | 30
5P20RR016457-10 30 | 30
5P41RR000592-40 30 | 30
5P41RR000592-41 30 | 30
5P41RR000862-36 30 | 30
5P41RR007707-17 30 | 30
5P51RR000166-48 30 | 30
5P60DE013079-03 30 | 30
5P60DE013079-04 30 | 30
5U54AI057168-09 30 | 30
5U54AI057168-10 30 | 30
2U54AI057168-06 29 | 29

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.34520 2413.2 212
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Interleukin-15 IL15 Tbio Non-IDG -3.01964 1248.2 612
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Toll-like receptor 7 TLR7 Tclin Non-IDG -2.92878 974.2 670
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.11277 1238.0 122
Alpha-synuclein SNCA Tchem Non-IDG -3.59982 3997.3 1484
Retinoschisin RS1 Tbio Non-IDG -2.46364 308.0 22