Development Level

Tbio 52 | 10,625
Tchem 35 | 1,890
Tclin 16 | 602

IMPC Term

preweaning lethality, complete... 8 | 633
abnormal retina morphology 4 | 100
embryonic lethality prior to t... 4 | 187
abnormal behavior 3 | 226
abnormal embryo size 3 | 112
abnormal neural tube closure 3 | 37
decreased lean body mass 3 | 195
preweaning lethality, incomple... 3 | 260
abnormal bone structure 2 | 131
abnormal hindbrain development 2 | 24
abnormal lens morphology 2 | 73
abnormal midbrain development 2 | 22
abnormal retinal pigmentation 2 | 61
decreased blood urea nitrogen ... 2 | 31
decreased bone mineral content 2 | 157
decreased circulating LDL chol... 2 | 37
embryonic lethality prior to o... 2 | 148
increased lean body mass 2 | 107
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal coping response 1 | 12
abnormal craniofacial morpholo... 1 | 12
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal forebrain morphology 1 | 4
abnormal heart left ventricle ... 1 | 20
abnormal hindbrain morphology 1 | 2
abnormal humerus morphology 1 | 11
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal midbrain morphology 1 | 2
abnormal retinal vasculature m... 1 | 15
abnormal tail morphology 1 | 17
abnormal vocalization 1 | 21
absent startle reflex 1 | 15
cataract 1 | 26
cyanosis 1 | 6
decreased basophil cell number 1 | 11
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating triglyce... 1 | 83
decreased follicular B cell nu... 1 | 4
decreased kidney weight 1 | 7
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased spleen weight 1 | 13
decreased total body fat amoun... 1 | 186
edema 1 | 11
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
hemorrhage 1 | 12
hydrops fetalis 1 | 22
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
increased B cell number 1 | 23
increased NK T cell number 1 | 11
increased T cell number 1 | 15
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating choleste... 1 | 53
increased circulating insulin ... 1 | 2
increased eosinophil cell numb... 1 | 9
increased fasted circulating g... 1 | 68
increased gamma-delta T cell n... 1 | 16
increased heart weight 1 | 37
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased startle reflex 1 | 38
mydriasis 1 | 9
respiratory system phenotype 1 | 2
tremors 1 | 34

Disease

ovarian cancer 64 | 8,484
Cancer 60 | 2,346
osteosarcoma 58 | 7,933
glioblastoma 43 | 5,572
lung cancer 40 | 4,466
medulloblastoma, large-cell 40 | 6,234
psoriasis 36 | 6,685
Breast cancer 34 | 3,094
atypical teratoid / rhabdoid tumor 33 | 4,369
malignant mesothelioma 29 | 3,162
diabetes mellitus 27 | 1,663
lung carcinoma 27 | 2,844
pancreatic cancer 27 | 2,300
pilocytic astrocytoma 25 | 3,086
interstitial cystitis 24 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
invasive ductal carcinoma 24 | 2,950
pediatric high grade glioma 24 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
oligodendroglioma 23 | 2,849
astrocytic glioma 22 | 2,241
primitive neuroectodermal tumor 22 | 3,031
ulcerative colitis 22 | 2,087
Carcinoma 21 | 2,147
non-small cell lung cancer 21 | 2,798
tuberculosis 21 | 1,557
Obesity 19 | 616
ductal carcinoma in situ 19 | 1,745
ependymoma 19 | 2,514
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,795
subependymal giant cell astrocytoma 19 | 2,287
Multiple myeloma 17 | 1,327
astrocytoma 17 | 1,493
lung adenocarcinoma 17 | 2,713
Kidney disease 16 | 396
adult high grade glioma 16 | 2,148
dermatomyositis 15 | 933
group 4 medulloblastoma 15 | 1,875
medulloblastoma 15 | 1,524
posterior fossa group B ependymoma 15 | 1,530
Alzheimer's disease 14 | 644
Mammary Neoplasms 14 | 410
Stomach Neoplasms 14 | 282
cystic fibrosis 14 | 1,665
nasopharyngeal carcinoma 14 | 1,056
Atherosclerosis 13 | 275
Hypertension 13 | 287
Liver carcinoma 13 | 217
Schizophrenia 13 | 501
acute quadriplegic myopathy 13 | 1,157
breast carcinoma 13 | 1,614
cutaneous lupus erythematosus 13 | 1,056
juvenile dermatomyositis 13 | 1,189
pituitary cancer 13 | 1,972
posterior fossa group A ependymoma 13 | 1,511
Adenocarcinoma 12 | 115
Heart disease 12 | 279
Lung Neoplasms 12 | 171
Neurodegenerative disease 12 | 383
Pick disease 12 | 1,893
Prostatic Neoplasms 12 | 471
colon cancer 12 | 1,475
Adenoma 11 | 165
Cerebrovascular disease 11 | 231
Coronary artery disease 11 | 240
Endometriosis 11 | 535
Vascular disease 11 | 281
adrenocortical carcinoma 11 | 1,427
Atopic dermatitis 10 | 944
Duchenne muscular dystrophy 10 | 602
Hypertensive disease 10 | 193
Renal Cell Carcinoma 10 | 199
Rheumatoid Arthritis 10 | 1,160
esophageal adenocarcinoma 10 | 737
group 3 medulloblastoma 10 | 2,254
Arthritis 9 | 248
Asthma 9 | 349
Polycystic Ovary Syndrome 9 | 332
Toxic encephalopathy 9 | 131
non primary Sjogren syndrome sicca 9 | 840
sonic hedgehog group medulloblastoma 9 | 1,482
Anemia 8 | 252
Esophageal Neoplasms 8 | 67
Intellectual disability 8 | 573
Liver disease 8 | 219
Lung disease 8 | 132
Melanoma 8 | 261
Multiple Sclerosis 8 | 498
Osteoporosis 8 | 257
active Crohn's disease 8 | 918
atypical teratoid/rhabdoid tumor 8 | 1,095
gastric carcinoma 8 | 832
primary pancreatic ductal adenocarcinoma 8 | 1,271
Crohn's disease 7 | 304
Peripheral vascular disease 7 | 90
Waldenstrons macroglobulinemia 7 | 765
aldosterone-producing adenoma 7 | 664
pancreatic carcinoma 7 | 567
primary Sjogren syndrome 7 | 789

Tissue

Blood and immune system 102 | 17,995
Cardiovascular System 102 | 17,958
Digestive Tract 102 | 18,473
Endocrine System 102 | 18,512
Female tissues 102 | 18,647
Liver and Pancreas 102 | 18,136
Male tissues 102 | 17,969
Nervous System 102 | 18,561
Respiratory system 102 | 17,484
Skin and soft tissues 102 | 18,115
Urinary Tract 102 | 18,444

Target Family

Enzyme 45 | 4,146
Non-IDG 32 | 11,971
Transcription Factor 10 | 1,400
Kinase 8 | 634
Ion Channel 2 | 341
Nuclear Receptor 2 | 48
Transporter 2 | 473
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

Grant Application

5P41RR001646-20 103 | 103
3P41RR001209-23S1 157 | 157
5P41RR001209-22 157 | 157
5P41RR001209-23 157 | 157
2P51RR000165-51 139 | 139
5P51RR000163-52 136 | 136
5P51RR000163-51 132 | 132
5P51RR000165-50 130 | 130
2P51RR000163-50 128 | 128
5P51RR000164-48 127 | 127
5P51RR000164-50 125 | 125
5P51RR000164-49 112 | 112
5P51RR000165-49 106 | 106
5P41RR001646-19 103 | 103
7P51RR000163-41 100 | 100
2P41RR011823-16 99 | 99
5P51RR000163-42 98 | 98
5P51RR000163-43 98 | 98
5P41RR001081-24 94 | 94
5P41RR001646-18 90 | 90
5P41RR015301-09 82 | 82
5P51RR000167-49 78 | 78
5P41RR002250-26 65 | 65
5P51RR000168-40 65 | 65
5P51RR000168-41 65 | 65
5P41RR001646-27 64 | 64
5P51RR000165-40 63 | 63
5M01RR000188-45 60 | 60
3P41RR010888-05S1 59 | 59
5M01RR000030-40 58 | 58
5M01RR000096-39 57 | 57
5P41RR000954-25 57 | 57
5P41RR000954-26 57 | 57
2P41RR000954-33 56 | 56
5P41RR010888-14 56 | 56
5P41RR012408-13 55 | 55
5M01RR000188-46 53 | 53
5P41RR001646-28 52 | 52
5P51RR000167-48 52 | 52
5P51RR000168-49 52 | 52
5P41RR001646-29 51 | 51
2P41RR002250-25 50 | 50
5M01RR000188-47 50 | 50
5P51RR000166-39 47 | 47
5M01RR000043-40 46 | 46
5P51RR000168-50 46 | 46
5P41RR010888-15 45 | 45
5P41RR015301-08 45 | 45
5P41RR004050-13 44 | 44
5M01RR000847-37 43 | 43
5P41RR004050-12 43 | 43
5P51RR000167-50 43 | 43
5P51RR000169-50 43 | 43
5P41RR000954-34 42 | 42
2P41RR004050-21 41 | 41
5P41RR010888-13 41 | 41
5P51RR000168-48 41 | 41
5P51RR000167-40 40 | 40
5P41RR015301-07 39 | 39
5P51RR000164-39 39 | 39
5P51RR000168-39 39 | 39
2P51RR000169-49 38 | 38
5P51RR000169-48 38 | 38
5P41RR004050-23 37 | 37
5P51RR013986-13 37 | 37
3P51RR000167-46S2 36 | 36
5P41RR001008-25 36 | 36
5M01RR000043-49 35 | 35
5P20RR021905-04 35 | 35
5P41RR004050-22 35 | 35
5M01RR000040-40 34 | 34
5P20RR016481-10 34 | 34
5P41RR001315-19 34 | 34
3P60DE013079-01S1 32 | 32
5M01RR000833-26 32 | 32
5P20RR016481-11 32 | 32
5P20RR020152-07 32 | 32
5P41RR000862-38 32 | 32
5P51RR000166-49 32 | 32
5P60DE013079-02 32 | 32
5S06GM008037-29 32 | 32
5S06GM008037-30 32 | 32
5U41RR007707-10 32 | 32
2P20RR016480-09 31 | 31
5M01RR000827-34 31 | 31
5P41RR002250-24 31 | 31
5P41RR005959-22 31 | 31
5P41RR018522-08 31 | 31
3P60DE013079-03S1 30 | 30
5P20RR016457-10 30 | 30
5P41RR000592-40 30 | 30
5P41RR000592-41 30 | 30
5P41RR000862-36 30 | 30
5P41RR007707-17 30 | 30
5P51RR000166-48 30 | 30
5P60DE013079-03 30 | 30
5P60DE013079-04 30 | 30
5U54AI057168-09 30 | 30
5U54AI057168-10 30 | 30
2U54AI057168-06 29 | 29

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Apolipoprotein A-I APOA1 Tchem Non-IDG -3.60439 3516.7 901
Protein-tyrosine kinase 6 PTK6 Tchem Kinase -2.14303 167.1 320
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Elongation factor Tu, mitochondrial TUFM Tbio Non-IDG -1.18045 17.6 186
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.59332 3912.4 208
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.17963 1388.1 188
Lysozyme C LYZ Tbio Enzyme -3.63761 4321.0 420
GMP synthase [glutamine-hydrolyzing] GMPS Tchem Enzyme -2.43758 281.7 169
Peptidyl-prolyl cis-trans isomerase FKBP1A FKBP1A Tclin Enzyme -2.75744 370.6 255