Development Level

Tbio 48 | 10,625
Tchem 29 | 1,890
Tclin 13 | 602

IMPC Term

preweaning lethality, complete... 8 | 633
abnormal retina morphology 4 | 100
embryonic lethality prior to t... 4 | 187
abnormal behavior 3 | 226
abnormal embryo size 3 | 112
abnormal neural tube closure 3 | 37
decreased lean body mass 3 | 195
abnormal bone structure 2 | 131
abnormal hindbrain development 2 | 24
abnormal lens morphology 2 | 73
abnormal midbrain development 2 | 22
abnormal retinal pigmentation 2 | 61
decreased blood urea nitrogen ... 2 | 31
decreased bone mineral content 2 | 157
decreased circulating LDL chol... 2 | 37
embryonic lethality prior to o... 2 | 148
increased lean body mass 2 | 107
preweaning lethality, incomple... 2 | 260
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal coping response 1 | 12
abnormal craniofacial morpholo... 1 | 12
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal forebrain morphology 1 | 4
abnormal heart left ventricle ... 1 | 20
abnormal hindbrain morphology 1 | 2
abnormal humerus morphology 1 | 11
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal midbrain morphology 1 | 2
abnormal retinal vasculature m... 1 | 15
abnormal tail morphology 1 | 17
abnormal vocalization 1 | 21
absent startle reflex 1 | 15
cataract 1 | 26
cyanosis 1 | 6
decreased basophil cell number 1 | 11
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating triglyce... 1 | 83
decreased follicular B cell nu... 1 | 4
decreased kidney weight 1 | 7
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased spleen weight 1 | 13
decreased total body fat amoun... 1 | 186
edema 1 | 11
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
hemorrhage 1 | 12
hydrops fetalis 1 | 22
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
increased B cell number 1 | 23
increased NK T cell number 1 | 11
increased T cell number 1 | 15
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating choleste... 1 | 53
increased circulating insulin ... 1 | 2
increased eosinophil cell numb... 1 | 9
increased fasted circulating g... 1 | 68
increased gamma-delta T cell n... 1 | 16
increased heart weight 1 | 37
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased startle reflex 1 | 38
mydriasis 1 | 9
respiratory system phenotype 1 | 2

Disease

ovarian cancer 57 | 8,484
osteosarcoma 52 | 7,933
Cancer 48 | 2,346
glioblastoma 38 | 5,572
medulloblastoma, large-cell 37 | 6,234
lung cancer 33 | 4,466
Breast cancer 31 | 3,094
atypical teratoid / rhabdoid tumor 30 | 4,369
psoriasis 30 | 6,685
malignant mesothelioma 26 | 3,162
pediatric high grade glioma 23 | 2,712
pilocytic astrocytoma 23 | 3,086
pancreatic cancer 22 | 2,300
diabetes mellitus 21 | 1,663
lung carcinoma 21 | 2,844
astrocytic glioma 20 | 2,241
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
oligodendroglioma 20 | 2,849
primitive neuroectodermal tumor 20 | 3,031
tuberculosis 20 | 1,557
interstitial cystitis 19 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
invasive ductal carcinoma 19 | 2,950
Carcinoma 18 | 2,147
subependymal giant cell astrocytoma 18 | 2,287
ulcerative colitis 18 | 2,087
Obesity 17 | 616
ependymoma 17 | 2,514
non-small cell lung cancer 17 | 2,798
astrocytoma 16 | 1,493
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
Multiple myeloma 15 | 1,327
ductal carcinoma in situ 15 | 1,745
adult high grade glioma 14 | 2,148
Kidney disease 13 | 396
cystic fibrosis 13 | 1,665
dermatomyositis 13 | 933
group 4 medulloblastoma 13 | 1,875
medulloblastoma 13 | 1,524
posterior fossa group B ependymoma 13 | 1,530
lung adenocarcinoma 12 | 2,713
Adenocarcinoma 11 | 115
Alzheimer's disease 11 | 644
Atherosclerosis 11 | 275
Heart disease 11 | 279
Hypertension 11 | 287
Mammary Neoplasms 11 | 410
Schizophrenia 11 | 501
acute quadriplegic myopathy 11 | 1,157
colon cancer 11 | 1,475
juvenile dermatomyositis 11 | 1,189
nasopharyngeal carcinoma 11 | 1,056
Adenoma 10 | 165
Coronary artery disease 10 | 240
Endometriosis 10 | 535
Liver carcinoma 10 | 217
Neurodegenerative disease 10 | 383
Pick disease 10 | 1,893
Stomach Neoplasms 10 | 282
adrenocortical carcinoma 10 | 1,427
cutaneous lupus erythematosus 10 | 1,056
group 3 medulloblastoma 10 | 2,254
pituitary cancer 10 | 1,972
Atopic dermatitis 9 | 944
Cerebrovascular disease 9 | 231
Hypertensive disease 9 | 193
Lung Neoplasms 9 | 171
Prostatic Neoplasms 9 | 471
Renal Cell Carcinoma 9 | 199
Vascular disease 9 | 281
breast carcinoma 9 | 1,614
posterior fossa group A ependymoma 9 | 1,511
Asthma 8 | 349
Duchenne muscular dystrophy 8 | 602
Polycystic Ovary Syndrome 8 | 332
Rheumatoid Arthritis 8 | 1,160
Toxic encephalopathy 8 | 131
gastric carcinoma 8 | 832
sonic hedgehog group medulloblastoma 8 | 1,482
Anemia 7 | 252
Arthritis 7 | 248
Esophageal Neoplasms 7 | 67
Intellectual disability 7 | 573
Liver disease 7 | 219
Melanoma 7 | 261
Metabolic syndrome X 7 | 155
Osteoporosis 7 | 257
esophageal adenocarcinoma 7 | 737
pancreatic carcinoma 7 | 567
primary pancreatic ductal adenocarcinoma 7 | 1,271
Lipid metabolism disorder 6 | 102
Lung disease 6 | 132
Multiple Sclerosis 6 | 498
Peripheral vascular disease 6 | 90
active Crohn's disease 6 | 918
aldosterone-producing adenoma 6 | 664
atypical teratoid/rhabdoid tumor 6 | 1,095
non primary Sjogren syndrome sicca 6 | 840
primary Sjogren syndrome 6 | 789

Tissue

Blood and immune system 89 | 17,995
Cardiovascular System 89 | 17,958
Digestive Tract 89 | 18,473
Endocrine System 89 | 18,512
Female tissues 89 | 18,647
Liver and Pancreas 89 | 18,136
Male tissues 89 | 17,969
Nervous System 89 | 18,561
Respiratory system 89 | 17,484
Skin and soft tissues 89 | 18,115
Urinary Tract 89 | 18,444

Target Family

Enzyme 43 | 4,146
Non-IDG 30 | 11,971
Transcription Factor 7 | 1,400
Kinase 4 | 634
Nuclear Receptor 2 | 48
Transporter 2 | 473
Ion Channel 1 | 341
TF/Epigenetic 1 | 38

Grant Application

5P41RR001646-18 90 | 90
3P41RR001209-23S1 157 | 157
5P41RR001209-22 157 | 157
5P41RR001209-23 157 | 157
2P51RR000165-51 139 | 139
5P51RR000163-52 136 | 136
5P51RR000163-51 132 | 132
5P51RR000165-50 130 | 130
2P51RR000163-50 128 | 128
5P51RR000164-48 127 | 127
5P51RR000164-50 125 | 125
5P51RR000164-49 112 | 112
5P51RR000165-49 106 | 106
5P41RR001646-19 103 | 103
5P41RR001646-20 103 | 103
7P51RR000163-41 100 | 100
2P41RR011823-16 99 | 99
5P51RR000163-42 98 | 98
5P51RR000163-43 98 | 98
5P41RR001081-24 94 | 94
5P41RR015301-09 82 | 82
5P51RR000167-49 78 | 78
5P41RR002250-26 65 | 65
5P51RR000168-40 65 | 65
5P51RR000168-41 65 | 65
5P41RR001646-27 64 | 64
5P51RR000165-40 63 | 63
5M01RR000188-45 60 | 60
3P41RR010888-05S1 59 | 59
5M01RR000030-40 58 | 58
5M01RR000096-39 57 | 57
5P41RR000954-25 57 | 57
5P41RR000954-26 57 | 57
2P41RR000954-33 56 | 56
5P41RR010888-14 56 | 56
5P41RR012408-13 55 | 55
5M01RR000188-46 53 | 53
5P41RR001646-28 52 | 52
5P51RR000167-48 52 | 52
5P51RR000168-49 52 | 52
5P41RR001646-29 51 | 51
2P41RR002250-25 50 | 50
5M01RR000188-47 50 | 50
5P51RR000166-39 47 | 47
5M01RR000043-40 46 | 46
5P51RR000168-50 46 | 46
5P41RR010888-15 45 | 45
5P41RR015301-08 45 | 45
5P41RR004050-13 44 | 44
5M01RR000847-37 43 | 43
5P41RR004050-12 43 | 43
5P51RR000167-50 43 | 43
5P51RR000169-50 43 | 43
5P41RR000954-34 42 | 42
2P41RR004050-21 41 | 41
5P41RR010888-13 41 | 41
5P51RR000168-48 41 | 41
5P51RR000167-40 40 | 40
5P41RR015301-07 39 | 39
5P51RR000164-39 39 | 39
5P51RR000168-39 39 | 39
2P51RR000169-49 38 | 38
5P51RR000169-48 38 | 38
5P41RR004050-23 37 | 37
5P51RR013986-13 37 | 37
3P51RR000167-46S2 36 | 36
5P41RR001008-25 36 | 36
5M01RR000043-49 35 | 35
5P20RR021905-04 35 | 35
5P41RR004050-22 35 | 35
5M01RR000040-40 34 | 34
5P20RR016481-10 34 | 34
5P41RR001315-19 34 | 34
3P60DE013079-01S1 32 | 32
5M01RR000833-26 32 | 32
5P20RR016481-11 32 | 32
5P20RR020152-07 32 | 32
5P41RR000862-38 32 | 32
5P51RR000166-49 32 | 32
5P60DE013079-02 32 | 32
5S06GM008037-29 32 | 32
5S06GM008037-30 32 | 32
5U41RR007707-10 32 | 32
2P20RR016480-09 31 | 31
5M01RR000827-34 31 | 31
5P41RR002250-24 31 | 31
5P41RR005959-22 31 | 31
5P41RR018522-08 31 | 31
3P60DE013079-03S1 30 | 30
5P20RR016457-10 30 | 30
5P41RR000592-40 30 | 30
5P41RR000592-41 30 | 30
5P41RR000862-36 30 | 30
5P41RR007707-17 30 | 30
5P51RR000166-48 30 | 30
5P60DE013079-03 30 | 30
5P60DE013079-04 30 | 30
5U54AI057168-09 30 | 30
5U54AI057168-10 30 | 30
2U54AI057168-06 29 | 29

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Apolipoprotein A-I APOA1 Tchem Non-IDG -3.60439 3516.7 901
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Elongation factor Tu, mitochondrial TUFM Tbio Non-IDG -1.18045 17.6 186
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.59332 3912.4 208
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.17963 1388.1 188
GMP synthase [glutamine-hydrolyzing] GMPS Tchem Enzyme -2.43758 281.7 169
Peptidyl-prolyl cis-trans isomerase FKBP1A FKBP1A Tclin Enzyme -2.75744 370.6 255
10 kDa heat shock protein, mitochondrial HSPE1 Tbio Non-IDG -3.00667 987.9 390
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.07424 1194.2 1600
Glutathione reductase, mitochondrial GSR Tclin Enzyme -2.97339 830.6 224