Development Level

Tbio 87 | 10,625
Tchem 48 | 1,890
Tclin 20 | 602
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 11 | 633
embryonic lethality prior to o... 4 | 148
embryonic lethality prior to t... 4 | 187
decreased body weight 3 | 174
abnormal behavior 2 | 226
abnormal embryo size 2 | 112
decreased circulating LDL chol... 2 | 37
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
increased blood urea nitrogen ... 2 | 44
increased or absent threshold ... 2 | 128
preweaning lethality, incomple... 2 | 260
tremors 2 | 34
abnormal allantois morphology 1 | 3
abnormal bone mineralization 1 | 55
abnormal chorioallantoic fusio... 1 | 2
abnormal embryo turning 1 | 15
abnormal femur morphology 1 | 14
abnormal limb bud morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
abnormal tail bud morphology 1 | 6
decreased CD4-positive, CD25-p... 1 | 24
decreased CD5-positive Ly6C-po... 1 | 4
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating iron lev... 1 | 25
decreased gamma-delta T cell n... 1 | 18
decreased granulocyte number 1 | 8
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
embryonic growth retardation 1 | 28
enlarged heart 1 | 111
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased CD8-positive, alpha-... 1 | 11
increased KLRG1-positive NK ce... 1 | 9
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating chloride... 1 | 43
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased gamma-delta T cell n... 1 | 16
increased lean body mass 1 | 107
increased rib number 1 | 41
increased transitional stage T... 1 | 1
pale yolk sac 1 | 12
pallor 1 | 13
small kidney 1 | 10
small superior vagus ganglion 1 | 20

Disease

ovarian cancer 84 | 8,484
Cancer 83 | 2,346
psoriasis 75 | 6,685
osteosarcoma 72 | 7,933
lung cancer 65 | 4,466
glioblastoma 56 | 5,572
medulloblastoma, large-cell 50 | 6,234
Breast cancer 43 | 3,094
diabetes mellitus 43 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 43 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,988
invasive ductal carcinoma 40 | 2,950
lung adenocarcinoma 40 | 2,713
non-small cell lung cancer 39 | 2,798
lung carcinoma 38 | 2,844
pancreatic cancer 37 | 2,300
atypical teratoid / rhabdoid tumor 36 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,956
malignant mesothelioma 35 | 3,162
interstitial cystitis 34 | 2,299
primitive neuroectodermal tumor 31 | 3,031
pediatric high grade glioma 30 | 2,712
ulcerative colitis 30 | 2,087
oligodendroglioma 29 | 2,849
pilocytic astrocytoma 29 | 3,086
Carcinoma 27 | 2,147
Kidney disease 27 | 396
breast carcinoma 25 | 1,614
colon cancer 25 | 1,475
pituitary cancer 25 | 1,972
Anemia 24 | 252
ductal carcinoma in situ 24 | 1,745
astrocytic glioma 23 | 2,241
subependymal giant cell astrocytoma 23 | 2,287
tuberculosis 23 | 1,557
ependymoma 22 | 2,514
group 3 medulloblastoma 22 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,795
Multiple myeloma 21 | 1,327
Atopic dermatitis 20 | 944
Heart disease 20 | 279
Waldenstrons macroglobulinemia 20 | 765
astrocytoma 20 | 1,493
Atherosclerosis 19 | 275
cystic fibrosis 19 | 1,665
Obesity 18 | 616
Pick disease 18 | 1,893
acute quadriplegic myopathy 18 | 1,157
nasopharyngeal carcinoma 18 | 1,056
primary pancreatic ductal adenocarcinoma 18 | 1,271
Alzheimer's disease 17 | 644
Neurodegenerative disease 17 | 383
Toxic encephalopathy 17 | 131
dermatomyositis 17 | 933
posterior fossa group A ependymoma 17 | 1,511
Hypertension 16 | 287
Vascular disease 16 | 281
adrenocortical carcinoma 16 | 1,427
adult high grade glioma 16 | 2,148
posterior fossa group B ependymoma 16 | 1,530
Cerebrovascular disease 15 | 231
Rheumatoid Arthritis 15 | 1,160
Schizophrenia 15 | 501
atypical teratoid/rhabdoid tumor 15 | 1,095
cutaneous lupus erythematosus 15 | 1,056
esophageal adenocarcinoma 15 | 737
group 4 medulloblastoma 15 | 1,875
Asthma 14 | 349
Down syndrome 14 | 548
Endometriosis 14 | 535
Mammary Neoplasms 14 | 410
Peripheral Neuropathy 14 | 303
spina bifida 14 | 1,064
Coronary artery disease 13 | 240
Diarrhea 13 | 155
medulloblastoma 13 | 1,524
Amyotrophic Lateral Sclerosis 12 | 431
Autistic Disorder 12 | 320
Liver disease 12 | 219
Stomach Neoplasms 12 | 282
gastric carcinoma 12 | 832
non primary Sjogren syndrome sicca 12 | 840
sonic hedgehog group medulloblastoma 12 | 1,482
Hypersensitivity reaction type II disease 11 | 235
Parkinson's disease 11 | 364
progressive supranuclear palsy 11 | 674
Arthritis 10 | 248
Hypertensive disease 10 | 193
Intellectual disability 10 | 573
Malaria 10 | 140
Multiple Sclerosis 10 | 498
primary Sjogren syndrome 10 | 789
Bipolar Disorder 9 | 266
Colonic Neoplasms 9 | 126
IGA Glomerulonephritis 9 | 454
Liver carcinoma 9 | 217
chronic rhinosinusitis 9 | 512
hepatocellular carcinoma 9 | 532
juvenile dermatomyositis 9 | 1,189
mucosa-associated lymphoid tissue lymphoma 9 | 480

Tissue

Endocrine System 155 | 18,512
Female tissues 155 | 18,647
Nervous System 155 | 18,561
Urinary Tract 155 | 18,444
Cardiovascular System 154 | 17,958
Digestive Tract 154 | 18,473
Skin and soft tissues 154 | 18,115
Blood and immune system 153 | 17,995
Liver and Pancreas 153 | 18,136
Male tissues 152 | 17,969
Respiratory system 151 | 17,484

Target Family

Non-IDG 67 | 11,971
Enzyme 60 | 4,146
Kinase 19 | 634
Transcription Factor 6 | 1,400
Ion Channel 2 | 341
GPCR 1 | 406
TF/Epigenetic 1 | 38
Transporter 1 | 473

Grant Application

3P41RR001209-23S1 157 | 157
5P41RR001209-22 157 | 157
5P41RR001209-23 157 | 157
2P51RR000165-51 139 | 139
5P51RR000163-52 136 | 136
5P51RR000163-51 132 | 132
5P51RR000165-50 130 | 130
2P51RR000163-50 128 | 128
5P51RR000164-48 127 | 127
5P51RR000164-50 125 | 125
5P51RR000164-49 112 | 112
5P51RR000165-49 106 | 106
5P41RR001646-19 103 | 103
5P41RR001646-20 103 | 103
7P51RR000163-41 100 | 100
2P41RR011823-16 99 | 99
5P51RR000163-42 98 | 98
5P51RR000163-43 98 | 98
5P41RR001081-24 94 | 94
5P41RR001646-18 90 | 90
5P41RR015301-09 82 | 82
5P51RR000167-49 78 | 78
5P41RR002250-26 65 | 65
5P51RR000168-40 65 | 65
5P51RR000168-41 65 | 65
5P41RR001646-27 64 | 64
5P51RR000165-40 63 | 63
5M01RR000188-45 60 | 60
3P41RR010888-05S1 59 | 59
5M01RR000030-40 58 | 58
5M01RR000096-39 57 | 57
5P41RR000954-25 57 | 57
5P41RR000954-26 57 | 57
2P41RR000954-33 56 | 56
5P41RR010888-14 56 | 56
5P41RR012408-13 55 | 55
5M01RR000188-46 53 | 53
5P41RR001646-28 52 | 52
5P51RR000167-48 52 | 52
5P51RR000168-49 52 | 52
5P41RR001646-29 51 | 51
2P41RR002250-25 50 | 50
5M01RR000188-47 50 | 50
5P51RR000166-39 47 | 47
5M01RR000043-40 46 | 46
5P51RR000168-50 46 | 46
5P41RR010888-15 45 | 45
5P41RR015301-08 45 | 45
5P41RR004050-13 44 | 44
5M01RR000847-37 43 | 43
5P41RR004050-12 43 | 43
5P51RR000167-50 43 | 43
5P51RR000169-50 43 | 43
5P41RR000954-34 42 | 42
2P41RR004050-21 41 | 41
5P41RR010888-13 41 | 41
5P51RR000168-48 41 | 41
5P51RR000167-40 40 | 40
5P41RR015301-07 39 | 39
5P51RR000164-39 39 | 39
5P51RR000168-39 39 | 39
2P51RR000169-49 38 | 38
5P51RR000169-48 38 | 38
5P41RR004050-23 37 | 37
5P51RR013986-13 37 | 37
3P51RR000167-46S2 36 | 36
5P41RR001008-25 36 | 36
5M01RR000043-49 35 | 35
5P20RR021905-04 35 | 35
5P41RR004050-22 35 | 35
5M01RR000040-40 34 | 34
5P20RR016481-10 34 | 34
5P41RR001315-19 34 | 34
3P60DE013079-01S1 32 | 32
5M01RR000833-26 32 | 32
5P20RR016481-11 32 | 32
5P20RR020152-07 32 | 32
5P41RR000862-38 32 | 32
5P51RR000166-49 32 | 32
5P60DE013079-02 32 | 32
5S06GM008037-29 32 | 32
5S06GM008037-30 32 | 32
5U41RR007707-10 32 | 32
2P20RR016480-09 31 | 31
5M01RR000827-34 31 | 31
5P41RR002250-24 31 | 31
5P41RR005959-22 31 | 31
5P41RR018522-08 31 | 31
3P60DE013079-03S1 30 | 30
5P20RR016457-10 30 | 30
5P41RR000592-40 30 | 30
5P41RR000592-41 30 | 30
5P41RR000862-36 30 | 30
5P41RR007707-17 30 | 30
5P51RR000166-48 30 | 30
5P60DE013079-03 30 | 30
5P60DE013079-04 30 | 30
5U54AI057168-09 30 | 30
5U54AI057168-10 30 | 30
2U54AI057168-06 29 | 29

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Nucleolar GTP-binding protein 1 GTPBP4 Tbio Non-IDG -3.21425 1443.3 95
ELAV-like protein 2 ELAVL2 Tbio Non-IDG -2.09180 122.7 196
Apolipoprotein A-I APOA1 Tchem Non-IDG -3.60439 3516.7 901
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Protein-tyrosine kinase 6 PTK6 Tchem Kinase -2.14303 167.1 320
Cytochrome b MT-CYB Tbio Non-IDG -3.74473 5676.0 122
Hemopexin HPX Tbio Non-IDG -2.83364 677.6 363
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167