Development Level

Tbio 37 | 11,445
Tchem 11 | 1,598
Tdark 9 | 6,588
Tclin 7 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal bone structure 3 | 187
preweaning lethality, complete... 3 | 979
abnormal seminal vesicle morph... 2 | 114
decreased body weight 2 | 161
decreased vertical activity 2 | 208
enlarged heart 2 | 210
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal posture 1 | 2
abnormal retina morphology 1 | 71
abnormal snout morphology 1 | 23
absent pinna reflex 1 | 23
anophthalmia 1 | 33
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased B cell number 1 | 9
increased circulating fructosa... 1 | 13
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
male infertility 1 | 123
microphthalmia 1 | 26
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QRS complex duration 1 | 8
small superior vagus ganglion 1 | 74
vertebral transformation 1 | 12

Disease

Carcinoma 44 | 11,493
osteosarcoma 38 | 7,950
ovarian cancer 34 | 8,520
medulloblastoma, large-cell 24 | 6,241
psoriasis 23 | 6,694
glioblastoma 22 | 5,792
Cancer 19 | 2,499
atypical teratoid / rhabdoid tumor 19 | 5,112
group 3 medulloblastoma 18 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
lung cancer 18 | 4,740
adult high grade glioma 16 | 3,801
malignant mesothelioma 15 | 3,232
invasive ductal carcinoma 14 | 2,951
lung adenocarcinoma 14 | 2,716
pancreatic cancer 14 | 2,398
Astrocytoma, Pilocytic 13 | 3,081
Breast cancer 13 | 3,578
ductal carcinoma in situ 13 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
ependymoma 12 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung carcinoma 11 | 2,843
Kidney cancer 10 | 2,613
interstitial cystitis 10 | 2,312
pituitary cancer 10 | 1,972
Rheumatoid arthritis 9 | 1,191
active Crohn's disease 9 | 922
non-small cell lung cancer 9 | 2,890
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
ulcerative colitis 9 | 1,819
active ulcerative colitis 8 | 764
acute quadriplegic myopathy 8 | 1,158
diabetes mellitus 8 | 1,728
Autosomal recessive predisposition 7 | 1,442
Liver cancer 7 | 604
Multiple myeloma 7 | 1,332
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
primary pancreatic ductal adenocarcinoma 7 | 1,109
subependymal giant cell astrocytoma 7 | 2,287
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
astrocytic glioma 6 | 2,597
juvenile dermatomyositis 6 | 1,187
oligodendroglioma 6 | 2,850
primary Sjogren syndrome 6 | 735
Asthma 5 | 385
Carcinoma, Hepatocellular 5 | 228
Duchenne muscular dystrophy 5 | 601
Fever 5 | 138
Liver carcinoma 5 | 240
Multiple Sclerosis 5 | 540
colon cancer 5 | 1,478
dermatomyositis 5 | 966
esophageal adenocarcinoma 5 | 737
group 4 medulloblastoma 5 | 1,855
Alzheimer's disease 4 | 658
Amyotrophic lateral sclerosis 4 | 451
Breast Neoplasms 4 | 445
Fatigue 4 | 182
Intellectual disability 4 | 1,016
Male infertility 4 | 206
Mammary Neoplasms 4 | 425
Mammary Neoplasms, Experimental 4 | 154
Muscle hypotonia 4 | 571
Obesity 4 | 678
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 783
aldosterone-producing adenoma 4 | 665
gastric carcinoma 4 | 807
medulloblastoma 4 | 720
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
posterior fossa group A ependymoma 4 | 468
spina bifida 4 | 1,074
Anemia 3 | 365
Atherosclerosis 3 | 291
Bipolar Disorder 3 | 666
Byzanthine arch palate 3 | 194
Down syndrome 3 | 499
Essential Hypertension 3 | 94
Glaucoma 3 | 239
Hypereosinophilic syndrome 3 | 71
Hypertension 3 | 396
Hypoglycemia 3 | 152
Kidney disease 3 | 430
Leukemia 3 | 104
Liver Cirrhosis, Experimental 3 | 769
Neurodegenerative disease 3 | 414
Neuropathy 3 | 261
Polycystic ovary syndrome 3 | 360
Vasculitis 3 | 80
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
fibroadenoma 3 | 559
non diabetic and post-ischemic heart failure 3 | 200
posterior fossa group B ependymoma 3 | 416
progressive supranuclear palsy 3 | 676

Tissue

Digestive Tract 59 | 17,369
Female tissues 59 | 17,400
Skin and soft tissues 59 | 17,230
Blood and immune system 58 | 16,909
Endocrine System 58 | 18,159
Nervous System 57 | 16,725
Liver and Pancreas 56 | 16,750
Male tissues 55 | 17,142
Urinary Tract 55 | 16,678
Respiratory system 54 | 16,393
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 31 | 12,091
Enzyme 12 | 4,145
Transcription Factor 9 | 1,400
GPCR 4 | 408
Kinase 3 | 634
Transporter 3 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344

GWAS Trait

White blood cell count (basoph... 64 | 64
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tetraspanin-32 TSPAN32 Tbio Non-IDG -0.97140 8.31 153
Zinc finger protein ZFPM2 ZFPM2 Tbio Transcription Factor -1.78912 62.9 93
N-acetylated-alpha-linked acidic dipeptidase 2 NAALAD2 Tchem Enzyme -1.51589 30.6 39
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
P2Y purinoceptor 2 P2RY2 Tclin GPCR -2.74629 565.7 192
AF4/FMR2 family member 1 AFF1 Tbio Transcription Factor -2.60388 403.1 201
Contactin-4 CNTN4 Tbio Non-IDG -1.54832 35.6 117
Putative uncharacterized protein encoded by LINC00299 LINC00299 Tdark Non-IDG 0.00000 0
Histone-lysine N-methyltransferase SETD2 SETD2 Tchem Epigenetic -2.83266 645.3 214
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 RPN1 Tbio Enzyme -2.17901 146.5 319