Development Level

Tbio 105 | 11,445
Tdark 31 | 6,588
Tchem 20 | 1,598
Tclin 16 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal behavior 5 | 298
cataract 5 | 92
decreased body weight 5 | 161
decreased circulating choleste... 5 | 93
abnormal lens morphology 4 | 81
decreased body length 4 | 101
decreased bone mineral density 4 | 126
enlarged heart 4 | 210
increased circulating alkaline... 4 | 122
preweaning lethality, incomple... 4 | 499
abnormal bone structure 3 | 187
abnormal gait 3 | 69
decreased bone mineral content 3 | 151
decreased circulating HDL chol... 3 | 68
decreased circulating chloride... 3 | 30
decreased circulating glucose ... 3 | 126
decreased grip strength 3 | 116
decreased lean body mass 3 | 135
decreased total body fat amoun... 3 | 207
hyperactivity 3 | 148
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased circulating fructosa... 3 | 13
increased neutrophil cell numb... 3 | 46
prenatal lethality prior to he... 3 | 87
abnormal coat-hair pigmentatio... 2 | 64
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal maxilla morphology 2 | 17
abnormal retina morphology 2 | 71
corneal opacity 2 | 32
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
increased circulating alanine ... 2 | 13
increased circulating calcium ... 2 | 34
increased circulating potassiu... 2 | 29
increased circulating total pr... 2 | 28
increased fasted circulating g... 2 | 76
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased or absent threshold ... 2 | 101
short tibia 2 | 97
thrombocytopenia 2 | 56
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal head morphology 1 | 10
abnormal lung morphology 1 | 26
abnormal motor capabilities-co... 1 | 5
abnormal neural tube closure 1 | 46
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
long tibia 1 | 25
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 111 | 11,493
osteosarcoma 92 | 7,950
ovarian cancer 87 | 8,520
psoriasis 75 | 6,694
glioblastoma 67 | 5,792
lung cancer 65 | 4,740
medulloblastoma, large-cell 62 | 6,241
Cancer 51 | 2,499
lung carcinoma 49 | 2,843
atypical teratoid / rhabdoid tumor 48 | 5,112
Breast cancer 46 | 3,578
adult high grade glioma 46 | 3,801
non-small cell lung cancer 46 | 2,890
invasive ductal carcinoma 45 | 2,951
Astrocytoma, Pilocytic 43 | 3,081
group 3 medulloblastoma 43 | 4,104
pancreatic cancer 43 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,291
lung adenocarcinoma 41 | 2,716
tuberculosis 40 | 2,010
ependymoma 39 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,955
Rheumatoid arthritis 33 | 1,191
interstitial cystitis 33 | 2,312
primitive neuroectodermal tumor 33 | 3,035
ulcerative colitis 33 | 1,819
cystic fibrosis 31 | 1,696
malignant mesothelioma 31 | 3,232
subependymal giant cell astrocytoma 31 | 2,287
Kidney cancer 26 | 2,613
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
diabetes mellitus 24 | 1,728
astrocytic glioma 23 | 2,597
cutaneous lupus erythematosus 22 | 1,057
group 4 medulloblastoma 22 | 1,855
oligodendroglioma 22 | 2,850
breast carcinoma 20 | 1,638
juvenile dermatomyositis 20 | 1,187
pituitary cancer 20 | 1,972
Pick disease 19 | 1,894
ductal carcinoma in situ 19 | 1,745
primary Sjogren syndrome 19 | 735
Schizophrenia 17 | 1,160
Atopic dermatitis 16 | 952
Multiple Sclerosis 16 | 540
Multiple myeloma 16 | 1,332
Autosomal recessive predisposition 15 | 1,442
Melanoma 15 | 711
Type 2 diabetes mellitus 15 | 272
Asthma 14 | 385
Intellectual disability 14 | 1,016
acute myeloid leukemia 14 | 783
acute quadriplegic myopathy 14 | 1,158
spina bifida 14 | 1,074
Anemia 13 | 365
Muscle hypotonia 13 | 571
Waldenstrons macroglobulinemia 13 | 765
astrocytoma 13 | 1,146
colon cancer 13 | 1,478
gastric carcinoma 13 | 807
pediatric high grade glioma 13 | 1,064
Acquired metabolic disease 12 | 336
Arthritis 12 | 290
Atherosclerosis 12 | 291
Bipolar Disorder 12 | 666
Breast Neoplasms 12 | 445
Cognitive delay 12 | 608
Coronary artery disease 12 | 268
Global developmental delay 12 | 608
Kidney disease 12 | 430
Mammary Neoplasms 12 | 425
Mental and motor retardation 12 | 608
active ulcerative colitis 12 | 764
adrenocortical carcinoma 12 | 1,428
hepatocellular carcinoma 12 | 547
mucosa-associated lymphoid tissue lymphoma 12 | 484
pancreatic carcinoma 12 | 562
Crohn's disease 11 | 321
Hypersensitivity reaction type II disease 11 | 253
Obesity 11 | 678
dermatomyositis 11 | 966
Alzheimer's disease 10 | 658
Arthritis, Rheumatoid 10 | 174
Autistic Disorder 10 | 364
Duchenne muscular dystrophy 10 | 601
Dull intelligence 10 | 645
Liver Cirrhosis, Experimental 10 | 769
Liver cancer 10 | 604
Low intelligence 10 | 645
Major Depressive Disorder 10 | 301
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
Skin cancer 10 | 469
active Crohn's disease 10 | 922
nasopharyngeal carcinoma 10 | 1,058
periodontitis 10 | 293
Short stature 9 | 531
gastric cancer 9 | 459

Tissue

Endocrine System 158 | 18,159
Female tissues 157 | 17,400
Blood and immune system 156 | 16,909
Digestive Tract 155 | 17,369
Skin and soft tissues 155 | 17,230
Respiratory system 153 | 16,393
Liver and Pancreas 152 | 16,750
Urinary Tract 152 | 16,678
Nervous System 151 | 16,725
Male tissues 150 | 17,142
Cardiovascular System 142 | 15,192

Target Family

Non-IDG 93 | 12,091
Enzyme 37 | 4,145
Transcription Factor 15 | 1,400
Kinase 9 | 634
GPCR 7 | 408
Epigenetic 5 | 242
Transporter 3 | 473
oGPCR 3 | 421

GWAS Trait

White blood cell count 172 | 172
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 45 member 4 SLC45A4 Tdark Transporter 0.30 0.50 12
ATPase family AAA domain-containing protein 2B ATAD2B Tchem Epigenetic 0.27 1.01 18
Olfactory receptor 52A1 OR52A1 Tdark oGPCR 0.18 1.00 92
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
Gasdermin-A GSDMA Tbio Non-IDG -1.44401 26.7 77
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
GTP:AMP phosphotransferase AK3, mitochondrial AK3 Tbio Kinase -1.37969 23.5 249
Psoriasis susceptibility 1 candidate gene 1 protein PSORS1C1 Tbio Non-IDG -0.99481 11.0 63
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37
Polycomb group RING finger protein 3 PCGF3 Tdark Non-IDG -0.48328 1.97 115