Development Level

Tbio 19 | 11,445
Tdark 3 | 6,588
Tchem 2 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 2 | 220
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
brachydactyly 1 | 19
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased lymphocyte cell numb... 1 | 32
prenatal lethality prior to he... 1 | 87
syndactyly 1 | 23

Disease

Acquired metabolic disease 18 | 336
Carcinoma 18 | 11,493
osteosarcoma 14 | 7,950
ovarian cancer 14 | 8,520
Obesity 8 | 678
psoriasis 8 | 6,694
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pancreatic cancer 5 | 2,398
tuberculosis 5 | 2,010
Astrocytoma, Pilocytic 4 | 3,081
Cancer 4 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
Attention deficit hyperactivity disorder 3 | 278
Body Weight 3 | 14
Mental Depression 3 | 333
Pick disease 3 | 1,894
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
non primary Sjogren syndrome sicca 3 | 891
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
ulcerative colitis 3 | 1,819
Alcoholic Intoxication, Chronic 2 | 289
Alzheimer's disease 2 | 658
Asthma 2 | 385
Autism Spectrum Disorders 2 | 75
Autistic Disorder 2 | 364
Bipolar Disorder 2 | 666
Chronic obstructive pulmonary disease 2 | 184
Deafness 2 | 198
Depressive disorder 2 | 409
Diabetes Mellitus, Type 2 2 | 142
Dull intelligence 2 | 645
Epilepsy 2 | 792
Hirschsprung Disease 2 | 31
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Major Depressive Disorder 2 | 301
Megacolon 2 | 29
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Mood Disorders 2 | 184
Multiple Sclerosis 2 | 540
Polycystic ovary syndrome 2 | 360
Poor school performance 2 | 645
Retinitis Pigmentosa 2 | 226
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Sensorineural hearing loss 2 | 106
Short stature 2 | 531
Type 2 diabetes mellitus 2 | 272
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
subependymal giant cell astrocytoma 2 | 2,287
substance-related disorder 2 | 162
Alcohol dependence 1 | 107
Arachnodactyly 1 | 49
Deafness, Autosomal Recessive 23 1 | 1
Ehlers-Danlos syndrome 1 | 43
Heroin dependence 1 | 30
Hyperuricemia 1 | 49
Language Disorders 1 | 13
Leukemia, Acute Myeloid 1 | 17
Leukemia, Myelocytic, Acute 1 | 120
Metabolic syndrome X 1 | 52
Panic disorder 1 | 61
USHER SYNDROME, TYPE ID 1 | 2
Usher Syndrome, Type 1 1 | 7
Usher Syndrome, Type I 1 | 6
Usher Syndrome, Type IF 1 | 1
Usher syndrome, type 1D 1 | 2
Usher syndrome, type 1F 1 | 1
Vitiligo 1 | 73

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Cardiovascular System 22 | 15,192
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Nervous System 21 | 16,725

Target Family

Non-IDG 13 | 12,091
Enzyme 6 | 4,145
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Kinase 1 | 634
oGPCR 1 | 421

GWAS Trait

Weight 24 | 24
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
A disintegrin and metalloproteinase with thrombospondin motifs 14 ADAMTS14 Tbio Enzyme -0.89572 7.58 29
Centrosomal protein of 120 kDa CEP120 Tbio Non-IDG -0.93215 7.32 49
Lipoma-preferred partner LPP Tbio Non-IDG -2.77949 582.6 164
BTB/POZ domain-containing protein KCTD15 KCTD15 Tbio Non-IDG -1.04860 11.7 176
Dual specificity phosphatase DUPD1 DUPD1 Tbio Enzyme -0.43334 2.53 42
Anaphase-promoting complex subunit 4 ANAPC4 Tbio Enzyme 0.43 0.13 156
Olfactory receptor 2Y1 OR2Y1 Tdark oGPCR -0.47712 3.00 81
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase MGAT1 Tchem Enzyme -1.89893 74.7 212
Pre-miRNA 5'-monophosphate methyltransferase BCDIN3D Tbio Enzyme -0.29281 2.93 22