Development Level

Tbio 80 | 11,445
Tdark 15 | 6,588
Tchem 9 | 1,598
Tclin 6 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal bone structure 7 | 187
abnormal embryo size 6 | 220
increased heart weight 4 | 62
increased startle reflex 4 | 112
preweaning lethality, incomple... 4 | 499
abnormal eye morphology 3 | 68
abnormal heart morphology 3 | 162
abnormal neural tube closure 3 | 46
decreased bone mineral content 3 | 151
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased vertical activity 3 | 208
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
hemorrhage 3 | 23
abnormal limb bud morphology 2 | 17
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
increased body length 2 | 32
increased bone mineral content 2 | 108
increased fasted circulating g... 2 | 76
increased mean corpuscular vol... 2 | 92
pale yolk sac 2 | 25
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal heart shape 1 | 5
abnormal hindbrain development 1 | 16
abnormal incisor morphology 1 | 4
abnormal limb morphology 1 | 13
abnormal liver size 1 | 5
abnormal lymph node morphology 1 | 3
abnormal midbrain development 1 | 20
abnormal placenta size 1 | 20
abnormal radius morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spinal cord morpholog... 1 | 9
abnormal stomach morphology 1 | 10
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
cleft palate 1 | 8
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
increased KLRG1-positive NK ce... 1 | 1
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
pale liver 1 | 6
pallor 1 | 34
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened RR interval 1 | 17
unresponsive to tactile stimul... 1 | 8
urinary bladder obstruction 1 | 4

Disease

Carcinoma 86 | 11,493
ovarian cancer 69 | 8,520
osteosarcoma 59 | 7,950
medulloblastoma, large-cell 53 | 6,241
glioblastoma 47 | 5,792
psoriasis 47 | 6,694
atypical teratoid / rhabdoid tumor 45 | 5,112
lung cancer 43 | 4,740
ependymoma 42 | 4,679
Acquired metabolic disease 37 | 336
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
malignant mesothelioma 33 | 3,232
Kidney cancer 32 | 2,613
adult high grade glioma 31 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
Astrocytoma, Pilocytic 29 | 3,081
pancreatic cancer 29 | 2,398
Cancer 28 | 2,499
group 3 medulloblastoma 28 | 4,104
non-small cell lung cancer 27 | 2,890
lung adenocarcinoma 26 | 2,716
Breast cancer 23 | 3,578
invasive ductal carcinoma 23 | 2,951
oligodendroglioma 23 | 2,850
primitive neuroectodermal tumor 23 | 3,035
lung carcinoma 22 | 2,843
interstitial cystitis 21 | 2,312
cystic fibrosis 20 | 1,696
adrenocortical carcinoma 18 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
tuberculosis 18 | 2,010
astrocytic glioma 17 | 2,597
subependymal giant cell astrocytoma 17 | 2,287
ulcerative colitis 17 | 1,819
group 4 medulloblastoma 16 | 1,855
pituitary cancer 16 | 1,972
Autosomal recessive predisposition 15 | 1,442
ductal carcinoma in situ 15 | 1,745
Obesity 14 | 678
Pick disease 14 | 1,894
astrocytoma 14 | 1,146
diabetes mellitus 12 | 1,728
primary pancreatic ductal adenocarcinoma 12 | 1,109
Brachydactyly 11 | 156
Intellectual disability 11 | 1,016
Liver cancer 11 | 604
Polycystic ovary syndrome 11 | 360
Rheumatoid arthritis 11 | 1,191
colon cancer 11 | 1,478
Acquired scoliosis 10 | 281
Crohn's disease 10 | 321
Curvature of spine 10 | 282
Short stature 10 | 531
dermatomyositis 10 | 966
gastric carcinoma 10 | 807
Epilepsy 9 | 792
Type 2 diabetes mellitus 9 | 272
active Crohn's disease 9 | 922
acute quadriplegic myopathy 9 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
breast carcinoma 9 | 1,638
juvenile dermatomyositis 9 | 1,187
nasopharyngeal carcinoma 9 | 1,058
spina bifida 9 | 1,074
Atopic dermatitis 8 | 952
Endometriosis 8 | 540
Orbital separation excessive 8 | 244
Osteoporosis 8 | 363
Schizophrenia 8 | 1,160
gastric cancer 8 | 459
progressive supranuclear palsy 8 | 676
Adenoma 7 | 167
Chronic obstructive pulmonary disease 7 | 184
Cleft Palate 7 | 271
Diabetes Mellitus, Non-Insulin-Dependent 7 | 145
Dull intelligence 7 | 645
Kidney disease 7 | 430
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Prostatic Neoplasms 7 | 495
Seizures 7 | 596
active ulcerative colitis 7 | 764
acute myeloid leukemia 7 | 783
cutaneous lupus erythematosus 7 | 1,057
pediatric high grade glioma 7 | 1,064
Cataract 6 | 297
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Mental and motor retardation 6 | 608
Micrognathism 6 | 275
Muscle hypotonia 6 | 571
aldosterone-producing adenoma 6 | 665
esophageal adenocarcinoma 6 | 737
limb girdle muscular dystrophy 2A 6 | 213
pancreatic carcinoma 6 | 562

Tissue

Digestive Tract 103 | 17,369
Blood and immune system 102 | 16,909
Endocrine System 102 | 18,159
Female tissues 102 | 17,400
Urinary Tract 102 | 16,678
Male tissues 101 | 17,142
Skin and soft tissues 101 | 17,230
Respiratory system 100 | 16,393
Liver and Pancreas 99 | 16,750
Nervous System 97 | 16,725
Cardiovascular System 91 | 15,192

Target Family

Non-IDG 57 | 12,091
Enzyme 22 | 4,145
Transcription Factor 17 | 1,400
Kinase 4 | 634
Epigenetic 3 | 242
Transporter 2 | 473
oGPCR 2 | 421
GPCR 1 | 408
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

GWAS Trait

Waist circumference adjusted f... 110 | 110
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative uncharacterized protein C17orf82 C17orf82 Tdark Non-IDG 0.00000 0
ATPase family AAA domain-containing protein 5 ATAD5 Tbio Enzyme -1.60534 42.9 117
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Homeobox protein Hox-C5 HOXC5 Tbio Transcription Factor -1.08912 11.9 114
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 Tclin Enzyme -2.97252 871.7 197
Juxtaposed with another zinc finger protein 1 JAZF1 Tbio Non-IDG -1.61585 42.8 94
Putative olfactory receptor 2W5 OR2W5 Tdark oGPCR 0.00000 0
Protein polybromo-1 PBRM1 Tchem TF/Epigenetic -1.92500 84.6 97
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128