Development Level

Tbio 50 | 11,445
Tdark 8 | 6,588
Tclin 5 | 613
Tchem 2 | 1,598

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal embryo size 6 | 220
hemorrhage 4 | 23
preweaning lethality, incomple... 4 | 499
abnormal eye morphology 3 | 68
decreased bone mineral content 3 | 151
decreased circulating HDL chol... 3 | 68
abnormal facial morphology 2 | 17
abnormal heart morphology 2 | 162
abnormal limb morphology 2 | 13
abnormal neural tube closure 2 | 46
decreased circulating choleste... 2 | 93
decreased vertical activity 2 | 208
enlarged heart 2 | 210
increased body length 2 | 32
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal head shape 1 | 10
abnormal heart shape 1 | 5
abnormal incisor morphology 1 | 4
abnormal limb bud morphology 1 | 17
abnormal lymph node morphology 1 | 3
abnormal outer ear morphology 1 | 3
abnormal radius morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
cleft palate 1 | 8
convulsive seizures 1 | 13
cyanosis 1 | 7
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
unresponsive to tactile stimul... 1 | 8
urinary bladder obstruction 1 | 4

Disease

Carcinoma 48 | 11,493
ovarian cancer 40 | 8,520
osteosarcoma 35 | 7,950
medulloblastoma, large-cell 33 | 6,241
psoriasis 31 | 6,694
glioblastoma 29 | 5,792
Acquired metabolic disease 28 | 336
atypical teratoid / rhabdoid tumor 28 | 5,112
ependymoma 28 | 4,679
lung cancer 25 | 4,740
Kidney cancer 21 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
malignant mesothelioma 21 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
group 3 medulloblastoma 19 | 4,104
lung carcinoma 19 | 2,843
non-small cell lung cancer 19 | 2,890
Astrocytoma, Pilocytic 18 | 3,081
adult high grade glioma 18 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
lung adenocarcinoma 17 | 2,716
oligodendroglioma 17 | 2,850
Breast cancer 16 | 3,578
Cancer 16 | 2,499
invasive ductal carcinoma 16 | 2,951
cystic fibrosis 15 | 1,696
adrenocortical carcinoma 14 | 1,428
interstitial cystitis 14 | 2,312
pancreatic cancer 14 | 2,398
astrocytic glioma 12 | 2,597
ductal carcinoma in situ 12 | 1,745
primitive neuroectodermal tumor 12 | 3,035
subependymal giant cell astrocytoma 12 | 2,287
tuberculosis 12 | 2,010
ulcerative colitis 12 | 1,819
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Pick disease 9 | 1,894
pituitary cancer 9 | 1,972
Autosomal recessive predisposition 8 | 1,442
Rheumatoid arthritis 8 | 1,191
astrocytoma 8 | 1,146
primary pancreatic ductal adenocarcinoma 8 | 1,109
Crohn's disease 7 | 321
breast carcinoma 7 | 1,638
Atopic dermatitis 6 | 952
Cleft Palate 6 | 271
Endometriosis 6 | 540
Intellectual disability 6 | 1,016
Obesity 6 | 678
Short stature 6 | 531
Type 2 diabetes mellitus 6 | 272
gastric cancer 6 | 459
group 4 medulloblastoma 6 | 1,855
Acquired scoliosis 5 | 281
Chronic obstructive pulmonary disease 5 | 184
Cognitive delay 5 | 608
Craniofacial Abnormalities 5 | 151
Curvature of spine 5 | 282
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Global developmental delay 5 | 608
Liver cancer 5 | 604
Melanoma 5 | 711
Mental and motor retardation 5 | 608
Orbital separation excessive 5 | 244
Polycystic ovary syndrome 5 | 360
Schizophrenia 5 | 1,160
Small head 5 | 374
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
colon cancer 5 | 1,478
dermatomyositis 5 | 966
gastric carcinoma 5 | 807
progressive supranuclear palsy 5 | 676
spina bifida 5 | 1,074
Alzheimer's disease 4 | 658
Arthritis, Rheumatoid 4 | 174
Cataract 4 | 297
Coronary artery disease 4 | 268
Diabetes Mellitus, Type 2 4 | 142
Dull intelligence 4 | 645
Glaucoma 4 | 239
Hypoplastic mandible condyle 4 | 275
Low intelligence 4 | 645
Mandibular hypoplasia 4 | 275
Mental deficiency 4 | 645
Multiple Sclerosis 4 | 540
Poor school performance 4 | 645
Prostatic Neoplasms 4 | 495
Umbilical hernia 4 | 93
Uranostaphyloschisis 4 | 167
active Crohn's disease 4 | 922
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
cutaneous lupus erythematosus 4 | 1,057
diabetes mellitus 4 | 1,728
juvenile dermatomyositis 4 | 1,187
limb girdle muscular dystrophy 2A 4 | 213
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
sonic hedgehog group medulloblastoma 4 | 467

Tissue

Blood and immune system 63 | 16,909
Digestive Tract 63 | 17,369
Endocrine System 63 | 18,159
Female tissues 63 | 17,400
Male tissues 63 | 17,142
Skin and soft tissues 63 | 17,230
Respiratory system 62 | 16,393
Urinary Tract 62 | 16,678
Liver and Pancreas 60 | 16,750
Nervous System 60 | 16,725
Cardiovascular System 54 | 15,192

Target Family

Non-IDG 36 | 12,091
Transcription Factor 13 | 1,400
Enzyme 8 | 4,145
Kinase 3 | 634
Epigenetic 2 | 242
Transporter 2 | 473
GPCR 1 | 408

GWAS Trait

Waist circumference adjusted f... 65 | 65
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Homeobox protein Hox-C5 HOXC5 Tbio Transcription Factor -1.08912 11.9 114
Vigilin HDLBP Tbio Non-IDG -2.01228 106.9 233
Putative uncharacterized protein C17orf82 C17orf82 Tdark Non-IDG 0.00000 0
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Dynein heavy chain 10, axonemal DNAH10 Tdark Non-IDG -0.45693 2.56 10
A disintegrin and metalloproteinase with thrombospondin motifs 3 ADAMTS3 Tbio Enzyme -0.75603 4.50 45
Gasdermin-C GSDMC Tdark Non-IDG -0.67744 3.26 108
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.55611 364.6 174
T-box transcription factor TBX15 TBX15 Tbio Transcription Factor -1.29899 21.5 123