Development Level
Tbio | 53 | 11,445 | |
Tdark | 10 | 6,588 | |
Tclin | 5 | 613 | |
Tchem | 4 | 1,598 |
Collection
GPCR: IDG Consortium (Complete... | 1 | 25 |
IMPC Phenotype
preweaning lethality, complete... | 8 | 979 | |
abnormal embryo size | 7 | 220 | |
preweaning lethality, incomple... | 5 | 499 | |
abnormal eye morphology | 4 | 68 | |
hemorrhage | 4 | 23 | |
abnormal neural tube closure | 3 | 46 | |
decreased bone mineral content | 3 | 151 | |
decreased circulating HDL chol... | 3 | 68 | |
abnormal bone structure | 2 | 187 | |
abnormal facial morphology | 2 | 17 | |
abnormal heart morphology | 2 | 162 | |
abnormal limb bud morphology | 2 | 17 | |
abnormal limb morphology | 2 | 13 | |
decreased circulating choleste... | 2 | 93 | |
decreased vertical activity | 2 | 208 | |
embryonic growth retardation | 2 | 106 | |
embryonic lethality prior to t... | 2 | 278 | |
enlarged heart | 2 | 210 | |
increased body length | 2 | 32 | |
pale yolk sac | 2 | 25 | |
abnormal behavioral response t... | 1 | 66 | |
abnormal body wall morphology | 1 | 9 | |
abnormal coat-hair pigmentatio... | 1 | 64 | |
abnormal cranium morphology | 1 | 36 | |
abnormal epididymis morphology | 1 | 42 | |
abnormal forebrain development | 1 | 20 | |
abnormal head shape | 1 | 10 | |
abnormal heart shape | 1 | 5 | |
abnormal hindbrain development | 1 | 16 | |
abnormal incisor morphology | 1 | 4 | |
abnormal liver size | 1 | 5 | |
abnormal lymph node morphology | 1 | 3 | |
abnormal midbrain development | 1 | 20 | |
abnormal outer ear morphology | 1 | 3 | |
abnormal placenta size | 1 | 20 | |
abnormal radius morphology | 1 | 8 | |
abnormal seminal vesicle morph... | 1 | 114 | |
abnormal sleep behavior | 1 | 70 | |
abnormal snout morphology | 1 | 23 | |
abnormal stomach morphology | 1 | 10 | |
abnormal tail morphology | 1 | 25 | |
abnormal tooth morphology | 1 | 24 | |
abnormal ulna morphology | 1 | 8 | |
cleft palate | 1 | 8 | |
convulsive seizures | 1 | 13 | |
cyanosis | 1 | 7 | |
decreased body length | 1 | 101 | |
decreased body weight | 1 | 161 | |
decreased bone mineral density | 1 | 126 | |
decreased caudal vertebrae num... | 1 | 53 | |
decreased circulating LDL chol... | 1 | 38 | |
decreased circulating alanine ... | 1 | 47 | |
decreased circulating aspartat... | 1 | 34 | |
decreased circulating glucose ... | 1 | 126 | |
decreased circulating iron lev... | 1 | 32 | |
decreased circulating phosphat... | 1 | 27 | |
decreased circulating serum al... | 1 | 82 | |
decreased circulating total pr... | 1 | 49 | |
decreased lean body mass | 1 | 135 | |
decreased lymphocyte cell numb... | 1 | 83 | |
decreased mean corpuscular hem... | 1 | 31 | |
decreased mean corpuscular vol... | 1 | 79 | |
decreased neutrophil cell numb... | 1 | 42 | |
decreased total body fat amoun... | 1 | 207 | |
embryonic lethality prior to o... | 1 | 239 | |
enlarged epididymis | 1 | 31 | |
enlarged lymph nodes | 1 | 37 | |
hyperactivity | 1 | 148 | |
increased CD4-positive, CD25-p... | 1 | 1 | |
increased KLRG1-positive NK ce... | 1 | 1 | |
increased NK cell number | 1 | 3 | |
increased anti-nuclear antigen... | 1 | 19 | |
increased blood urea nitrogen ... | 1 | 48 | |
increased body weight | 1 | 25 | |
increased bone mineral content | 1 | 108 | |
increased bone mineral density | 1 | 72 | |
increased circulating HDL chol... | 1 | 80 | |
increased circulating chloride... | 1 | 41 | |
increased circulating glucose ... | 1 | 24 | |
increased circulating sodium l... | 1 | 71 | |
increased circulating triglyce... | 1 | 42 | |
increased effector memory CD4-... | 1 | 1 | |
increased fasted circulating g... | 1 | 76 | |
increased grip strength | 1 | 41 | |
increased hemoglobin content | 1 | 45 | |
increased leukocyte cell numbe... | 1 | 47 | |
increased mean corpuscular hem... | 1 | 36 | |
increased mean corpuscular vol... | 1 | 92 | |
increased monocyte cell number | 1 | 63 | |
increased total body fat amoun... | 1 | 134 | |
pale liver | 1 | 6 | |
pallor | 1 | 34 | |
prolonged QT interval | 1 | 38 | |
prolonged ST segment | 1 | 36 | |
shortened RR interval | 1 | 17 | |
small superior vagus ganglion | 1 | 74 | |
unresponsive to tactile stimul... | 1 | 8 | |
urinary bladder obstruction | 1 | 4 |
Disease
Tissue
Blood and immune system | 70 | 16,909 | |
Digestive Tract | 70 | 17,369 | |
Endocrine System | 70 | 18,159 | |
Female tissues | 70 | 17,400 | |
Male tissues | 70 | 17,142 | |
Skin and soft tissues | 70 | 17,230 | |
Respiratory system | 69 | 16,393 | |
Urinary Tract | 69 | 16,678 | |
Liver and Pancreas | 67 | 16,750 | |
Nervous System | 67 | 16,725 | |
Cardiovascular System | 61 | 15,192 |
Target Family
Non-IDG | 40 | 12,091 | |
Transcription Factor | 13 | 1,400 | |
Enzyme | 10 | 4,145 | |
Kinase | 4 | 634 | |
Epigenetic | 2 | 242 | |
Transporter | 2 | 473 | |
GPCR | 1 | 408 |
GWAS Trait
Waist circumference adjusted f... | 72 | 72 | |
Obesity-related traits | 569 | 569 | |
Schizophrenia | 533 | 533 | |
Breast cancer | 492 | 492 | |
Body mass index | 379 | 379 | |
Height | 369 | 369 | |
Coronary artery disease | 367 | 367 | |
Blood protein levels | 351 | 351 | |
Post bronchodilator FEV1-FVC r... | 308 | 308 | |
Mean corpuscular volume | 283 | 283 | |
Platelet count | 275 | 275 | |
Intelligence (multi-trait anal... | 267 | 267 | |
Mean platelet volume | 253 | 253 | |
IgG glycosylation | 250 | 250 | |
Mean corpuscular hemoglobin | 238 | 238 | |
Inflammatory bowel disease | 235 | 235 | |
Plateletcrit | 227 | 227 | |
Crohn's disease | 215 | 215 | |
Type 2 diabetes | 210 | 210 | |
Red blood cell count | 191 | 191 | |
Monocyte count | 183 | 183 | |
Red cell distribution width | 182 | 182 | |
Eosinophil counts | 180 | 180 | |
Neuroticism | 180 | 180 | |
Platelet distribution width | 174 | 174 | |
Monocyte percentage of white c... | 173 | 173 | |
Post bronchodilator FEV1 | 173 | 173 | |
Sum eosinophil basophil counts | 173 | 173 | |
White blood cell count | 172 | 172 | |
3-hydroxy-1-methylpropylmercap... | 166 | 166 | |
Eosinophil percentage of granu... | 163 | 163 | |
Eosinophil percentage of white... | 163 | 163 | |
Reticulocyte fraction of red c... | 163 | 163 | |
Ulcerative colitis | 163 | 163 | |
Granulocyte percentage of myel... | 162 | 162 | |
Itch intensity from mosquito b... | 162 | 162 | |
Systemic lupus erythematosus | 159 | 159 | |
High light scatter reticulocyt... | 158 | 158 | |
Lymphocyte counts | 158 | 158 | |
Reticulocyte count | 158 | 158 | |
Blood metabolite levels | 157 | 157 | |
Neutrophil count | 154 | 154 | |
High light scatter reticulocyt... | 153 | 153 | |
Neutrophil percentage of granu... | 153 | 153 | |
3-hydroxypropylmercapturic aci... | 150 | 150 | |
Tonsillectomy | 149 | 149 | |
Diastolic blood pressure | 144 | 144 | |
Sum basophil neutrophil counts | 140 | 140 | |
Autism spectrum disorder or sc... | 134 | 134 | |
Myeloid white cell count | 133 | 133 | |
Granulocyte count | 132 | 132 | |
Sum neutrophil eosinophil coun... | 129 | 129 | |
Colorectal cancer | 126 | 126 | |
Alzheimer disease and age of o... | 124 | 124 | |
Multiple sclerosis | 124 | 124 | |
Cholesterol, total | 123 | 123 | |
Night sleep phenotypes | 123 | 123 | |
Lung cancer | 122 | 122 | |
Lymphocyte percentage of white... | 122 | 122 | |
Menarche (age at onset) | 122 | 122 | |
Neutrophil percentage of white... | 121 | 121 | |
Rheumatoid arthritis | 121 | 121 | |
Systolic blood pressure | 120 | 120 | |
Immature fraction of reticuloc... | 118 | 118 | |
Diisocyanate-induced asthma | 116 | 116 | |
HDL cholesterol | 116 | 116 | |
Allergic disease (asthma, hay ... | 115 | 115 | |
Educational attainment (years ... | 114 | 114 | |
Hematocrit | 113 | 113 | |
Hemoglobin concentration | 112 | 112 | |
LDL cholesterol | 110 | 110 | |
QT interval | 110 | 110 | |
Waist circumference adjusted f... | 110 | 110 | |
Mosquito bite size | 107 | 107 | |
Asthma | 106 | 106 | |
Lobe attachment (rater-scored ... | 103 | 103 | |
Peripheral arterial disease (t... | 101 | 101 | |
Pulse pressure | 97 | 97 | |
Bipolar disorder | 94 | 94 | |
Major depressive disorder | 94 | 94 | |
Prostate cancer | 92 | 92 | |
Parkinson's disease | 90 | 90 | |
Hip circumference adjusted for... | 89 | 89 | |
Metabolite levels | 87 | 87 | |
Triglycerides | 87 | 87 | |
Colonoscopy-negative controls ... | 85 | 85 | |
Mean corpuscular hemoglobin co... | 85 | 85 | |
Itch intensity from mosquito b... | 84 | 84 | |
Bipolar disorder and schizophr... | 83 | 83 | |
Resting heart rate | 82 | 82 | |
Macrophage inflammatory protei... | 81 | 81 | |
Migraine | 81 | 81 | |
Waist-to-hip ratio adjusted fo... | 81 | 81 | |
PR interval in Tripanosoma cru... | 80 | 80 | |
Cognitive performance | 79 | 79 | |
Glomerular filtration rate (cr... | 78 | 78 | |
Late-onset Alzheimer's disease | 78 | 78 | |
Waist circumference adjusted f... | 75 | 75 | |
Tuberculosis | 73 | 73 | |
Type 1 diabetes | 73 | 73 | |
Morning vs. evening chronotype | 72 | 72 |
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