Development Level

Tbio 50 | 11,445
Tdark 10 | 6,588
Tchem 6 | 1,598
Tclin 5 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal embryo size 4 | 220
decreased vertical activity 4 | 208
preweaning lethality, incomple... 4 | 499
abnormal heart morphology 3 | 162
decreased bone mineral content 3 | 151
enlarged heart 3 | 210
abnormal eye morphology 2 | 68
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
hemorrhage 2 | 23
increased body length 2 | 32
increased bone mineral content 2 | 108
increased mean corpuscular vol... 2 | 92
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart shape 1 | 5
abnormal incisor morphology 1 | 4
abnormal lymph node morphology 1 | 3
abnormal neural tube closure 1 | 46
abnormal radius morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spinal cord morpholog... 1 | 9
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
enlarged epididymis 1 | 31
hyperactivity 1 | 148
increased CD4-positive, CD25-p... 1 | 1
increased KLRG1-positive NK ce... 1 | 1
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased effector memory CD4-... 1 | 1
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
unresponsive to tactile stimul... 1 | 8
urinary bladder obstruction 1 | 4

Disease

Carcinoma 54 | 11,493
osteosarcoma 41 | 7,950
ovarian cancer 40 | 8,520
medulloblastoma, large-cell 36 | 6,241
glioblastoma 31 | 5,792
psoriasis 31 | 6,694
Acquired metabolic disease 30 | 336
atypical teratoid / rhabdoid tumor 30 | 5,112
ependymoma 28 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
lung cancer 25 | 4,740
adult high grade glioma 21 | 3,801
malignant mesothelioma 21 | 3,232
Astrocytoma, Pilocytic 20 | 3,081
Breast cancer 20 | 3,578
Kidney cancer 20 | 2,613
group 3 medulloblastoma 20 | 4,104
non-small cell lung cancer 20 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
oligodendroglioma 18 | 2,850
pancreatic cancer 18 | 2,398
lung adenocarcinoma 17 | 2,716
lung carcinoma 17 | 2,843
primitive neuroectodermal tumor 16 | 3,035
Cancer 15 | 2,499
invasive ductal carcinoma 15 | 2,951
astrocytic glioma 14 | 2,597
tuberculosis 14 | 2,010
cystic fibrosis 12 | 1,696
interstitial cystitis 12 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
ulcerative colitis 12 | 1,819
Autosomal recessive predisposition 10 | 1,442
Pick disease 10 | 1,894
adrenocortical carcinoma 10 | 1,428
ductal carcinoma in situ 10 | 1,745
subependymal giant cell astrocytoma 10 | 2,287
astrocytoma 9 | 1,146
colon cancer 9 | 1,478
primary pancreatic ductal adenocarcinoma 9 | 1,109
Type 2 diabetes mellitus 8 | 272
diabetes mellitus 8 | 1,728
group 4 medulloblastoma 8 | 1,855
Crohn's disease 7 | 321
Diabetes Mellitus, Non-Insulin-Dependent 7 | 145
Diabetes Mellitus, Type 2 7 | 142
Intellectual disability 7 | 1,016
Obesity 7 | 678
Osteoporosis 7 | 363
active Crohn's disease 7 | 922
acute quadriplegic myopathy 7 | 1,158
gastric carcinoma 7 | 807
progressive supranuclear palsy 7 | 676
Chronic obstructive pulmonary disease 6 | 184
Endometriosis 6 | 540
Prostatic Neoplasms 6 | 495
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
acute myeloid leukemia 6 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
dermatomyositis 6 | 966
gastric cancer 6 | 459
juvenile dermatomyositis 6 | 1,187
pituitary cancer 6 | 1,972
Breast Neoplasms 5 | 445
Epilepsy 5 | 792
Hypertension 5 | 396
Hypoplastic mandible condyle 5 | 275
Liver cancer 5 | 604
Mammary Neoplasms 5 | 425
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Short stature 5 | 531
breast carcinoma 5 | 1,638
esophageal adenocarcinoma 5 | 737
nasopharyngeal carcinoma 5 | 1,058
non-small cell lung carcinoma 5 | 317
pancreatic carcinoma 5 | 562
pediatric high grade glioma 5 | 1,064
Alzheimer's disease 4 | 658
Atopic dermatitis 4 | 952
Bipolar Disorder 4 | 666
Cardiovascular system disease 4 | 246
Cleft Palate 4 | 271
Liver Cirrhosis, Experimental 4 | 769
Melanoma 4 | 711
Multiple Sclerosis 4 | 540
Polycystic ovary syndrome 4 | 360
Prostate cancer 4 | 175
Seizures 4 | 596
active ulcerative colitis 4 | 764
aldosterone-producing adenoma 4 | 665
glioblastoma multiforme 4 | 142
limb girdle muscular dystrophy 2A 4 | 213
sonic hedgehog group medulloblastoma 4 | 467
spina bifida 4 | 1,074
Glaucoma 3 | 239
chronic rhinosinusitis 3 | 512
fibroadenoma 3 | 559

Tissue

Blood and immune system 68 | 16,909
Digestive Tract 68 | 17,369
Endocrine System 68 | 18,159
Female tissues 68 | 17,400
Urinary Tract 68 | 16,678
Male tissues 67 | 17,142
Skin and soft tissues 67 | 17,230
Respiratory system 66 | 16,393
Liver and Pancreas 65 | 16,750
Nervous System 63 | 16,725
Cardiovascular System 60 | 15,192

Target Family

Non-IDG 37 | 12,091
Enzyme 14 | 4,145
Transcription Factor 11 | 1,400
Epigenetic 3 | 242
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 344
TF/Epigenetic 1 | 38
Transporter 1 | 473

GWAS Trait

Waist circumference adjusted f... 71 | 71
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Homeobox protein Hox-C5 HOXC5 Tbio Transcription Factor -1.08912 11.9 114
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 Tclin Enzyme -2.97252 871.7 197
Putative uncharacterized protein C17orf82 C17orf82 Tdark Non-IDG 0.00000 0
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Carboxypeptidase A1 CPA1 Tchem Enzyme -1.95541 84.1 265
Protein polybromo-1 PBRM1 Tchem TF/Epigenetic -1.92500 84.6 97
Dynein heavy chain 10, axonemal DNAH10 Tdark Non-IDG -0.45693 2.56 10
A disintegrin and metalloproteinase with thrombospondin motifs 3 ADAMTS3 Tbio Enzyme -0.75603 4.50 45
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.55611 364.6 174