Development Level

Tbio 114 | 11,651
Tchem 24 | 1,388
Tdark 16 | 6,593
Tclin 9 | 612

Collection

GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
preweaning lethality, complete... 4 | 979
decreased mean corpuscular vol... 3 | 79
decreased vertical activity 3 | 208
increased mean corpuscular hem... 3 | 96
abnormal cornea morphology 2 | 31
decreased caudal vertebrae num... 2 | 53
decreased circulating aspartat... 2 | 34
decreased circulating glucose ... 2 | 126
decreased erythrocyte cell num... 2 | 62
decreased prepulse inhibition 2 | 82
enlarged heart 2 | 210
increased circulating alkaline... 2 | 122
increased circulating free fat... 2 | 20
increased erythrocyte cell num... 2 | 39
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin appearance 1 | 3
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal vertebrae morphology 1 | 18
cataract 1 | 92
decreased IgG3 level 1 | 1
decreased T cell number 1 | 15
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased thermal nociceptive ... 1 | 2
decreased threshold for audito... 1 | 26
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased fluid intake 1 | 1
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
long tibia 1 | 25
pallor 1 | 34
shortened QT interval 1 | 4
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Carcinoma 113 | 11,493
Crohn's disease 85 | 321
osteosarcoma 84 | 7,950
ovarian cancer 78 | 8,520
ulcerative colitis 77 | 1,819
psoriasis 71 | 6,694
glioblastoma 60 | 5,792
lung cancer 55 | 4,740
medulloblastoma, large-cell 52 | 6,241
Cancer 48 | 2,499
Astrocytoma, Pilocytic 46 | 3,081
atypical teratoid / rhabdoid tumor 46 | 5,112
malignant mesothelioma 46 | 3,232
adult high grade glioma 43 | 3,801
lung carcinoma 42 | 2,843
ependymoma 41 | 4,679
interstitial cystitis 38 | 2,312
Rheumatoid arthritis 37 | 1,191
tuberculosis 36 | 2,010
group 3 medulloblastoma 33 | 4,104
invasive ductal carcinoma 30 | 2,951
Kidney cancer 29 | 2,613
primitive neuroectodermal tumor 29 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
Colitis, Ulcerative 26 | 59
lung adenocarcinoma 25 | 2,716
oligodendroglioma 25 | 2,850
Breast cancer 24 | 3,578
cystic fibrosis 24 | 1,696
non-small cell lung cancer 24 | 2,890
astrocytic glioma 22 | 2,597
pancreatic cancer 22 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
diabetes mellitus 20 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
subependymal giant cell astrocytoma 20 | 2,287
Multiple Sclerosis 19 | 540
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
primary Sjogren syndrome 19 | 735
Pick disease 18 | 1,894
ductal carcinoma in situ 18 | 1,745
pituitary cancer 18 | 1,972
colon cancer 17 | 1,478
cutaneous lupus erythematosus 17 | 1,057
Asthma 16 | 385
active Crohn's disease 16 | 922
primary pancreatic ductal adenocarcinoma 16 | 1,109
Inflammatory bowel disease 15 | 151
Type 1 diabetes mellitus 15 | 109
breast carcinoma 15 | 1,638
juvenile dermatomyositis 15 | 1,187
Multiple myeloma 14 | 1,332
Systemic lupus erythematosus 14 | 194
acute myeloid leukemia 14 | 783
Atopic dermatitis 13 | 952
Autosomal recessive predisposition 13 | 1,442
Kidney disease 13 | 430
Liver Cirrhosis, Experimental 13 | 769
active ulcerative colitis 13 | 764
Arthritis 12 | 290
Pneumonia 12 | 174
Schizophrenia 12 | 1,160
medulloblastoma 12 | 720
Arthritis, Rheumatoid 11 | 174
Breast Neoplasms 11 | 445
Liver cancer 11 | 604
astrocytoma 11 | 1,146
dermatomyositis 11 | 966
group 4 medulloblastoma 11 | 1,855
non primary Sjogren syndrome sicca 11 | 891
pediatric high grade glioma 11 | 1,064
Arthralgia 10 | 90
Common variable immunodeficiency 10 | 101
Crohn Disease 10 | 45
Mammary Neoplasms 10 | 425
esophageal adenocarcinoma 10 | 737
gastric carcinoma 10 | 807
mucosa-associated lymphoid tissue lymphoma 10 | 484
Ankylosing spondylitis 9 | 140
Inflammatory Bowel Diseases 9 | 35
Lupus Erythematosus, Systemic 9 | 67
adrenocortical carcinoma 9 | 1,428
sarcoidosis 9 | 370
spina bifida 9 | 1,074
Alopecia areata 8 | 41
Celiac disease 8 | 116
Hepatomegaly 8 | 285
Hypertension 8 | 396
Obesity 8 | 678
Prostatic Neoplasms 8 | 495
Vascular disease 8 | 319
Waldenstrons macroglobulinemia 8 | 765
acute quadriplegic myopathy 8 | 1,158
interstitial lung disease 8 | 298
posterior fossa group A ependymoma 8 | 468
Bipolar Disorder 7 | 666
Depressive disorder 7 | 409
Immune system cancer 7 | 140
Primary biliary cirrhosis 7 | 51
gastric cancer 7 | 459

Tissue

Digestive Tract 157 | 17,369
Endocrine System 156 | 18,159
Skin and soft tissues 156 | 17,230
Blood and immune system 152 | 16,909
Female tissues 152 | 17,400
Male tissues 150 | 17,142
Urinary Tract 150 | 16,678
Liver and Pancreas 147 | 16,750
Nervous System 145 | 16,725
Respiratory system 145 | 16,393
Cardiovascular System 132 | 15,192

Target Family

Non-IDG 84 | 12,091
Enzyme 29 | 4,145
Transcription Factor 21 | 1,400
Kinase 8 | 634
GPCR 7 | 408
Epigenetic 6 | 242
Nuclear Receptor 3 | 48
Transporter 3 | 473
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

GWAS Trait

Ulcerative colitis 163 | 163
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
snRNA-activating protein complex subunit 4 SNAPC4 Tbio Transcription Factor -0.99715 10.0 160
Intelectin-1 ITLN1 Tbio Non-IDG -2.49500 337.0 194
Zinc finger protein Aiolos IKZF3 Tbio Transcription Factor -1.82293 59.0 314
C-X-C motif chemokine 5 CXCL5 Tbio Non-IDG -2.44551 266.4 370
Cyclic AMP-dependent transcription factor ATF-6 beta ATF6B Tbio Transcription Factor -1.03459 8.22 6
Insulin-like peptide INSL6 INSL6 Tdark Non-IDG -1.09303 12.2 34
GRAM domain-containing protein 1B GRAMD1B Tdark Non-IDG -0.37654 2.90 39
Proton myo-inositol cotransporter SLC2A13 Tbio Transporter -1.10021 10.8 71
Lipopolysaccharide-induced tumor necrosis factor-alpha factor LITAF Tbio Transcription Factor -2.03585 113.9 202
Ciliary neurotrophic factor CNTF Tbio Non-IDG -2.96004 1015.5 485