Development Level

Tbio 56 | 10,625
Tchem 16 | 1,890
Tdark 12 | 7,003
Tclin 5 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

decreased T cell number 2 | 31
decreased neutrophil cell numb... 2 | 37
increased circulating free fat... 2 | 17
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 93
preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 23
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased alpha-beta T cell nu... 1 | 12
decreased circulating amylase ... 1 | 24
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating sodium l... 1 | 18
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased lymphocyte cell numb... 1 | 9
decreased mean corpuscular hem... 1 | 19
decreased rib number 1 | 59
decreased thermal nociceptive ... 1 | 4
enlarged epididymis 1 | 27
enlarged heart 1 | 111
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased body length 1 | 20
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased effector memory CD4-... 1 | 15
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
increased thermal nociceptive ... 1 | 9
shortened QT interval 1 | 4
small superior vagus ganglion 1 | 20

Disease

Crohn's disease 58 | 304
ulcerative colitis 52 | 2,087
ovarian cancer 48 | 8,484
osteosarcoma 46 | 7,933
psoriasis 41 | 6,685
Inflammatory Bowel Diseases 38 | 87
glioblastoma 34 | 5,572
medulloblastoma, large-cell 31 | 6,234
lung cancer 27 | 4,466
atypical teratoid / rhabdoid tumor 26 | 4,369
Rheumatoid Arthritis 23 | 1,160
lung carcinoma 23 | 2,844
pilocytic astrocytoma 23 | 3,086
primitive neuroectodermal tumor 23 | 3,031
Cancer 21 | 2,346
Crohn Disease 21 | 97
Carcinoma 20 | 2,147
oligodendroglioma 20 | 2,849
malignant mesothelioma 19 | 3,162
pediatric high grade glioma 19 | 2,712
interstitial cystitis 18 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
tuberculosis 18 | 1,557
invasive ductal carcinoma 17 | 2,950
Multiple Sclerosis 15 | 498
astrocytic glioma 14 | 2,241
ependymoma 14 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
lung adenocarcinoma 14 | 2,713
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
Pick disease 13 | 1,893
adult high grade glioma 13 | 2,148
non-small cell lung cancer 12 | 2,798
group 3 medulloblastoma 11 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
pancreatic cancer 11 | 2,300
pituitary cancer 11 | 1,972
Breast cancer 10 | 3,094
Inflammatory bowel disease 10 | 142
Multiple myeloma 10 | 1,327
colon cancer 10 | 1,475
diabetes mellitus 10 | 1,663
posterior fossa group A ependymoma 10 | 1,511
subependymal giant cell astrocytoma 10 | 2,287
Diabetes Mellitus, Insulin-Dependent 9 | 76
Type 1 diabetes mellitus 9 | 101
breast carcinoma 9 | 1,614
cystic fibrosis 9 | 1,665
group 4 medulloblastoma 9 | 1,875
juvenile dermatomyositis 9 | 1,189
medulloblastoma 9 | 1,524
primary Sjogren syndrome 9 | 789
primary pancreatic ductal adenocarcinoma 9 | 1,271
Asthma 8 | 349
active Crohn's disease 8 | 918
cutaneous lupus erythematosus 8 | 1,056
dermatomyositis 8 | 933
ductal carcinoma in situ 8 | 1,745
sarcoidosis 8 | 358
Atopic dermatitis 7 | 944
Celiac disease 7 | 112
Kidney disease 7 | 396
acute myeloid leukemia 7 | 780
astrocytoma 7 | 1,493
atypical teratoid/rhabdoid tumor 7 | 1,095
gastric carcinoma 7 | 832
Alzheimer's disease 6 | 644
Gastrointestinal system disease 6 | 50
Hypersensitivity reaction type II disease 6 | 235
IGA Glomerulonephritis 6 | 454
active ulcerative colitis 6 | 477
sonic hedgehog group medulloblastoma 6 | 1,482
spina bifida 6 | 1,064
systemic lupus erythematosus 6 | 156
Acquired metabolic disease 5 | 267
Biliary cirrhosis 5 | 33
Heart disease 5 | 279
Inflammation 5 | 109
Lupus Erythematosus, Systemic 5 | 73
Prostatic Neoplasms 5 | 471
Vascular disease 5 | 281
Waldenstrons macroglobulinemia 5 | 765
esophageal adenocarcinoma 5 | 737
mucosa-associated lymphoid tissue lymphoma 5 | 480
nasopharyngeal carcinoma 5 | 1,056
non primary Sjogren syndrome sicca 5 | 840
non-small cell lung carcinoma 5 | 413
posterior fossa group B ependymoma 5 | 1,530
progressive supranuclear palsy 5 | 674
Arthritis 4 | 248
Colonic Neoplasms 4 | 126
Endometriosis 4 | 535
Peripheral T-cell lymphoma 4 | 24
Primary biliary cirrhosis 4 | 43
Prostate cancer 4 | 172
acute quadriplegic myopathy 4 | 1,157
aldosterone-producing adenoma 4 | 664
glioblastoma multiforme 4 | 347
head and neck cancer 4 | 270
tuberculosis and treatment for 6 months 4 | 686

Tissue

Blood and immune system 88 | 17,995
Cardiovascular System 88 | 17,958
Digestive Tract 88 | 18,473
Endocrine System 88 | 18,512
Nervous System 88 | 18,561
Skin and soft tissues 88 | 18,115
Urinary Tract 88 | 18,444
Female tissues 87 | 18,647
Male tissues 87 | 17,969
Liver and Pancreas 86 | 18,136
Respiratory system 86 | 17,484

Target Family

Non-IDG 45 | 11,971
Enzyme 20 | 4,146
Transcription Factor 8 | 1,400
Epigenetic 4 | 242
GPCR 4 | 406
Kinase 4 | 634
Nuclear Receptor 2 | 48
Ion Channel 1 | 341
Transporter 1 | 473

GWAS Trait

Ulcerative colitis 89 | 89
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mastermind-like protein 2 MAML2 Tbio Non-IDG -1.73604 61.8 100
HLA class II histocompatibility antigen, DQ alpha 1 chain HLA-DQA1 Tbio Non-IDG -2.93360 867.9 269
Low affinity immunoglobulin gamma Fc region receptor II-a FCGR2A Tbio Non-IDG -2.87960 775.0 717
Hepatocyte growth factor-like protein MST1 Tbio Enzyme -2.02220 90.5 0
Mothers against decapentaplegic homolog 3 SMAD3 Tbio Transcription Factor -3.03840 1043.2 1391
Psychosine receptor GPR65 Tbio GPCR -1.43622 31.9 163
Zinc finger protein 831 ZNF831 Tdark Transcription Factor 0.00000 5
Cyclin-Y CCNY Tbio Non-IDG -1.41033 27.8 102
Methylcytosine dioxygenase TET2 TET2 Tbio Enzyme -3.23763 1705.1 225
Interleukin-7 receptor subunit alpha IL7R Tbio Non-IDG -2.62557 528.6 688