Development Level

Tbio 145 | 11,445
Tdark 30 | 6,588
Tchem 23 | 1,598
Tclin 12 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 17 | 979
preweaning lethality, incomple... 7 | 499
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
abnormal gait 3 | 69
abnormal retina morphology 3 | 71
cataract 3 | 92
decreased prepulse inhibition 3 | 82
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
increased fasted circulating g... 3 | 76
increased lean body mass 3 | 172
increased mean corpuscular hem... 3 | 96
increased mean platelet volume 3 | 45
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
prenatal lethality prior to he... 3 | 87
short tibia 3 | 97
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal sleep behavior 2 | 70
decreased body weight 2 | 161
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased circulating choleste... 2 | 93
decreased circulating free fat... 2 | 31
decreased circulating fructosa... 2 | 30
decreased circulating glucose ... 2 | 126
decreased circulating phosphat... 2 | 27
decreased fasted circulating g... 2 | 65
decreased lactate dehydrogenas... 2 | 16
decreased lean body mass 2 | 135
decreased vertical activity 2 | 208
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating aspartat... 2 | 15
increased circulating choleste... 2 | 66
increased circulating total pr... 2 | 28
increased heart weight 2 | 62
small adrenal glands 2 | 16
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal eyelid morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal head size 1 | 6
abnormal lens morphology 1 | 81
abnormal lymph node morphology 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal spine curvature 1 | 9
abnormal startle reflex 1 | 15
abnormal vibrissa morphology 1 | 25
absent teeth 1 | 3
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cleft palate 1 | 8
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased fluid intake 1 | 3
decreased food intake 1 | 13
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
facial cleft 1 | 3
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased coping response 1 | 4
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
prolonged PQ interval 1 | 5
vertebral transformation 1 | 12

Disease

Carcinoma 142 | 11,493
ovarian cancer 103 | 8,520
osteosarcoma 95 | 7,950
glioblastoma 91 | 5,792
medulloblastoma, large-cell 89 | 6,241
Type 2 diabetes mellitus 80 | 272
psoriasis 79 | 6,694
atypical teratoid / rhabdoid tumor 73 | 5,112
lung cancer 71 | 4,740
ependymoma 70 | 4,679
adult high grade glioma 61 | 3,801
group 3 medulloblastoma 61 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 57 | 2,989
Diabetes Mellitus, Type 2 52 | 142
malignant mesothelioma 50 | 3,232
primitive neuroectodermal tumor 50 | 3,035
Breast cancer 49 | 3,578
Astrocytoma, Pilocytic 48 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 48 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 47 | 3,291
invasive ductal carcinoma 47 | 2,951
diabetes mellitus 46 | 1,728
Cancer 45 | 2,499
lung carcinoma 45 | 2,843
Kidney cancer 44 | 2,613
oligodendroglioma 44 | 2,850
astrocytic glioma 43 | 2,597
Diabetes Mellitus, Non-Insulin-Dependent 41 | 145
pancreatic cancer 40 | 2,398
non-small cell lung cancer 39 | 2,890
subependymal giant cell astrocytoma 38 | 2,287
interstitial cystitis 37 | 2,312
lung adenocarcinoma 37 | 2,716
pituitary cancer 37 | 1,972
ulcerative colitis 37 | 1,819
cystic fibrosis 36 | 1,696
Acquired metabolic disease 32 | 336
ductal carcinoma in situ 29 | 1,745
Pick disease 27 | 1,894
Schizophrenia 26 | 1,160
group 4 medulloblastoma 26 | 1,855
tuberculosis 26 | 2,010
breast carcinoma 25 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
Epilepsy 20 | 792
Intellectual disability 20 | 1,016
Melanoma 20 | 711
Obesity 20 | 678
astrocytoma 20 | 1,146
adrenocortical carcinoma 19 | 1,428
Autosomal recessive predisposition 18 | 1,442
juvenile dermatomyositis 18 | 1,187
Alzheimer's disease 17 | 658
acute quadriplegic myopathy 17 | 1,158
pediatric high grade glioma 17 | 1,064
Atopic dermatitis 16 | 952
Seizures 16 | 596
colon cancer 16 | 1,478
spina bifida 16 | 1,074
Cognitive delay 15 | 608
Global developmental delay 15 | 608
Mental and motor retardation 15 | 608
Multiple myeloma 15 | 1,332
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 510
Diabetes Mellitus, Noninsulin-Dependent 14 | 31
esophageal adenocarcinoma 14 | 737
Bipolar Disorder 13 | 666
Failure to gain weight 13 | 365
Pediatric failure to thrive 13 | 365
Polycystic ovary syndrome 13 | 360
Rheumatoid arthritis 13 | 1,191
gastric carcinoma 13 | 807
primary pancreatic ductal adenocarcinoma 13 | 1,109
Blepharoptosis 12 | 231
Colorectal Neoplasms 12 | 243
Dull intelligence 12 | 645
Hepatomegaly 12 | 285
Liver cancer 12 | 604
Low intelligence 12 | 645
Mental Depression 12 | 333
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Parkinson's disease 12 | 392
Poor school performance 12 | 645
Prostatic Neoplasms 12 | 495
Short stature 12 | 531
Skin cancer 12 | 469
Type 1 diabetes mellitus 12 | 109
active ulcerative colitis 12 | 764
acute myeloid leukemia 12 | 783
aldosterone-producing adenoma 12 | 665
cutaneous lupus erythematosus 12 | 1,057
Cardiovascular system disease 11 | 246
Depressive disorder 11 | 409
Duchenne muscular dystrophy 11 | 601
Osteoporosis 11 | 363
maturity-onset diabetes of the young 11 | 32
nasopharyngeal carcinoma 11 | 1,058
non primary Sjogren syndrome sicca 11 | 891
primary Sjogren syndrome 11 | 735

Tissue

Endocrine System 200 | 18,159
Digestive Tract 199 | 17,369
Female tissues 198 | 17,400
Skin and soft tissues 198 | 17,230
Male tissues 193 | 17,142
Nervous System 192 | 16,725
Urinary Tract 192 | 16,678
Liver and Pancreas 191 | 16,750
Blood and immune system 190 | 16,909
Respiratory system 187 | 16,393
Cardiovascular System 173 | 15,192

Target Family

Non-IDG 106 | 12,091
Enzyme 46 | 4,145
Transcription Factor 20 | 1,400
Transporter 12 | 473
Kinase 8 | 634
GPCR 6 | 408
Ion Channel 6 | 344
Epigenetic 4 | 242
Nuclear Receptor 2 | 48

GWAS Trait

Type 2 diabetes 210 | 210
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin-like growth factor 2 mRNA-binding protein 2 IGF2BP2 Tbio Non-IDG -1.77792 57.3 400
Probable G-protein coupled receptor 45 GPR45 Tbio GPCR -0.93863 8.13 120
COMM domain-containing protein 7 COMMD7 Tbio Non-IDG -0.95317 9.82 82
Zinc finger ZZ-type and EF-hand domain-containing protein 1 ZZEF1 Tdark Non-IDG 0.19 0.86 20
Dual specificity protein phosphatase 9 DUSP9 Tbio Enzyme -1.15238 17.2 202
Neurexin-3 NRXN3 Tbio Non-IDG -1.34072 34.8 172
Nucleosome assembly protein 1-like 4 NAP1L4 Tbio Non-IDG -0.84469 7.05 50
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 ARAP1 Tbio Non-IDG -0.99923 14.5 99
Sodium/hydrogen exchanger 9B2 SLC9B2 Tbio Transporter -1.21956 18.8 126
Zinc finger and BTB domain-containing protein 20 ZBTB20 Tbio Transcription Factor -2.14421 133.1 85