Development Level

Tbio 36 | 11,651
Tchem 9 | 1,388
Tclin 4 | 612
Tdark 4 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 4 | 979
hyperactivity 3 | 148
abnormal behavior 2 | 298
increased bone mineral density 2 | 72
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal outer ear morphology 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
anophthalmia 1 | 33
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased lactate dehydrogenas... 1 | 16
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased CD4-positive, CD25-p... 1 | 1
increased KLRG1-positive NK ce... 1 | 1
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased effector memory CD4-... 1 | 1
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
male infertility 1 | 123
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 35 | 11,493
ovarian cancer 29 | 8,520
osteosarcoma 27 | 7,950
psoriasis 22 | 6,694
glioblastoma 20 | 5,792
Cardiovascular system disease 17 | 246
medulloblastoma, large-cell 16 | 6,241
diabetes mellitus 15 | 1,728
atypical teratoid / rhabdoid tumor 14 | 5,112
Lipid metabolism disorder 13 | 114
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
lung cancer 13 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Breast cancer 12 | 3,578
ependymoma 12 | 4,679
Atherosclerosis 11 | 291
Obesity 11 | 678
group 3 medulloblastoma 11 | 4,104
oligodendroglioma 11 | 2,850
Cancer 10 | 2,499
Metabolic syndrome X 10 | 52
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
malignant mesothelioma 10 | 3,232
Coronary artery disease 9 | 268
Type 2 diabetes mellitus 9 | 272
astrocytoma 9 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung adenocarcinoma 9 | 2,716
Intellectual disability 8 | 1,016
astrocytic glioma 8 | 2,597
non-small cell lung cancer 8 | 2,890
pancreatic cancer 8 | 2,398
Acquired metabolic disease 7 | 336
Autosomal recessive predisposition 7 | 1,442
Schizophrenia 7 | 1,160
adult high grade glioma 7 | 3,801
tuberculosis 7 | 2,010
Astrocytoma, Pilocytic 6 | 3,081
Diabetes Mellitus, Non-Insulin-Dependent 6 | 145
Liver Cirrhosis, Experimental 6 | 769
Multiple myeloma 6 | 1,332
Vascular disease 6 | 319
breast carcinoma 6 | 1,638
dermatomyositis 6 | 966
primitive neuroectodermal tumor 6 | 3,035
spina bifida 6 | 1,074
ulcerative colitis 6 | 1,819
Autistic Disorder 5 | 364
Depressive disorder 5 | 409
Dull intelligence 5 | 645
Gout 5 | 104
Hypercholesterolemia, Familial 5 | 23
Hyperlipoproteinemia Type II 5 | 12
Hypertension 5 | 396
Kidney cancer 5 | 2,613
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
active Crohn's disease 5 | 922
adrenocortical carcinoma 5 | 1,428
chronic rhinosinusitis 5 | 512
group 4 medulloblastoma 5 | 1,855
hepatocellular carcinoma 5 | 547
interstitial cystitis 5 | 2,312
lung carcinoma 5 | 2,843
Alcoholic Intoxication, Chronic 4 | 289
Cognitive delay 4 | 608
Colonic Neoplasms 4 | 142
Diabetes Mellitus, Type 2 4 | 142
Epilepsy 4 | 792
Global developmental delay 4 | 608
Hyperlipidemia 4 | 43
Hypertriglyceridemia 4 | 17
Hypoplastic mandible condyle 4 | 275
Low Vision 4 | 174
Macular degeneration 4 | 65
Mandibular hypoplasia 4 | 275
Mental and motor retardation 4 | 608
Micrognathism 4 | 275
Prostatic Neoplasms 4 | 495
Proteinuria 4 | 144
Rheumatoid arthritis 4 | 1,191
Short nose 4 | 132
Short stature 4 | 531
Small nose 4 | 132
Visual Impairment 4 | 174
active ulcerative colitis 4 | 764
cystic fibrosis 4 | 1,696
esophageal adenocarcinoma 4 | 737
interstitial lung disease 4 | 298
invasive ductal carcinoma 4 | 2,951
mucosa-associated lymphoid tissue lymphoma 4 | 484
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
Attention deficit hyperactivity disorder 3 | 278
aldosterone-producing adenoma 3 | 665
nephrosclerosis 3 | 333

Tissue

Endocrine System 53 | 18,159
Female tissues 53 | 17,400
Liver and Pancreas 53 | 16,750
Digestive Tract 52 | 17,369
Male tissues 52 | 17,142
Skin and soft tissues 52 | 17,230
Urinary Tract 51 | 16,678
Blood and immune system 50 | 16,909
Nervous System 49 | 16,725
Respiratory system 49 | 16,393
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 16 | 4,145
Kinase 5 | 634
Transcription Factor 5 | 1,400
Epigenetic 1 | 242

GWAS Trait

Triglyceride levels 53 | 53
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
ADP-dependent glucokinase ADPGK Tbio Kinase -0.86342 7.82 154
Synembryn-B RIC8B Tbio Non-IDG -1.71667 50.1 40
Transcription factor MafF MAFF Tbio Transcription Factor -2.05095 108.7 94
SURP and G-patch domain-containing protein 1 SUGP1 Tbio Non-IDG -2.10410 126.5 120
Tribbles homolog 1 TRIB1 Tbio Kinase -1.74370 59.4 250
Vascular endothelial growth factor A VEGFA Tclin Non-IDG -4.27197 19076.6 1809
Apolipoprotein C-III APOC3 Tbio Non-IDG -2.93348 875.2 267
Hepatic triacylglycerol lipase LIPC Tchem Enzyme -2.56840 389.0 258
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein HERPUD1 Tbio Non-IDG -1.84801 68.9 188