Development Level

Tbio 101 | 11,445
Tdark 23 | 6,588
Tchem 14 | 1,598
Tclin 11 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 8 | 979
decreased total body fat amoun... 4 | 207
preweaning lethality, incomple... 4 | 499
abnormal lens morphology 3 | 81
decreased vertical activity 3 | 208
increased startle reflex 3 | 112
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal skin morphology 2 | 50
abnormal snout morphology 2 | 23
cataract 2 | 92
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
hemorrhage 2 | 23
hyperactivity 2 | 148
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 172
abnormal bone mineralization 1 | 38
abnormal colon morphology 1 | 3
abnormal cornea morphology 1 | 31
abnormal duodenum morphology 1 | 4
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal limb morphology 1 | 13
abnormal locomotor activation 1 | 16
abnormal outer ear morphology 1 | 3
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
increased thermal nociceptive ... 1 | 9
kinked tail 1 | 2
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
unresponsive to tactile stimul... 1 | 8
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 97 | 11,493
ovarian cancer 75 | 8,520
osteosarcoma 62 | 7,950
glioblastoma 53 | 5,792
medulloblastoma, large-cell 51 | 6,241
lung cancer 46 | 4,740
atypical teratoid / rhabdoid tumor 45 | 5,112
psoriasis 44 | 6,694
ependymoma 39 | 4,679
adult high grade glioma 36 | 3,801
Cancer 35 | 2,499
Astrocytoma, Pilocytic 31 | 3,081
primitive neuroectodermal tumor 28 | 3,035
ulcerative colitis 28 | 1,819
Breast cancer 27 | 3,578
invasive ductal carcinoma 27 | 2,951
interstitial cystitis 26 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
non-small cell lung cancer 26 | 2,890
subependymal giant cell astrocytoma 26 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
tuberculosis 25 | 2,010
Rheumatoid arthritis 24 | 1,191
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
lung carcinoma 24 | 2,843
group 3 medulloblastoma 23 | 4,104
oligodendroglioma 23 | 2,850
pituitary cancer 22 | 1,972
Kidney cancer 21 | 2,613
group 4 medulloblastoma 21 | 1,855
malignant mesothelioma 21 | 3,232
Crohn's disease 20 | 321
astrocytic glioma 20 | 2,597
astrocytoma 20 | 1,146
pancreatic cancer 20 | 2,398
Schizophrenia 19 | 1,160
Autosomal recessive predisposition 18 | 1,442
diabetes mellitus 18 | 1,728
ductal carcinoma in situ 17 | 1,745
juvenile dermatomyositis 17 | 1,187
lung adenocarcinoma 17 | 2,716
primary Sjogren syndrome 17 | 735
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Multiple Sclerosis 15 | 540
spina bifida 15 | 1,074
Multiple myeloma 14 | 1,332
primary pancreatic ductal adenocarcinoma 14 | 1,109
breast carcinoma 13 | 1,638
cystic fibrosis 13 | 1,696
gastric carcinoma 13 | 807
Type 1 diabetes mellitus 12 | 109
acute quadriplegic myopathy 12 | 1,158
cutaneous lupus erythematosus 12 | 1,057
Pick disease 11 | 1,894
Waldenstrons macroglobulinemia 10 | 765
pediatric high grade glioma 10 | 1,064
Celiac disease 9 | 116
Epilepsy 9 | 792
Hepatomegaly 9 | 285
Hypersensitivity reaction type II disease 9 | 253
Splenomegaly 9 | 190
adrenocortical carcinoma 9 | 1,428
Asthma 8 | 385
Bipolar Disorder 8 | 666
Fatigue 8 | 182
Immunologic Deficiency Syndromes 8 | 113
Intellectual disability 8 | 1,016
Kidney disease 8 | 430
acute myeloid leukemia 8 | 783
colon cancer 8 | 1,478
nasopharyngeal carcinoma 8 | 1,058
non primary Sjogren syndrome sicca 8 | 891
Autistic Disorder 7 | 364
Liver Cirrhosis, Experimental 7 | 769
Muscle hypotonia 7 | 571
Type 2 diabetes mellitus 7 | 272
Vitiligo 7 | 73
active ulcerative colitis 7 | 764
chronic rhinosinusitis 7 | 512
head and neck cancer and chronic obstructive pulmonary disease 7 | 239
periodontitis 7 | 293
sonic hedgehog group medulloblastoma 7 | 467
Acquired metabolic disease 6 | 336
Alzheimer's disease 6 | 658
Amyotrophic lateral sclerosis 6 | 451
Arthritis 6 | 290
Arthritis, Rheumatoid 6 | 174
Common variable immunodeficiency 6 | 101
Diarrhea 6 | 253
Essential Hypertension 6 | 94
Human immunodeficiency virus infectious disease 6 | 138
Obesity 6 | 678
Orbital separation excessive 6 | 244
Parkinson's disease 6 | 392
Seizures 6 | 596
Short stature 6 | 531
active Crohn's disease 6 | 922
aldosterone-producing adenoma 6 | 665
dermatomyositis 6 | 966
medulloblastoma 6 | 720

Tissue

Endocrine System 141 | 18,159
Digestive Tract 138 | 17,369
Skin and soft tissues 136 | 17,230
Blood and immune system 135 | 16,909
Female tissues 134 | 17,400
Liver and Pancreas 133 | 16,750
Male tissues 133 | 17,142
Nervous System 132 | 16,725
Respiratory system 130 | 16,393
Urinary Tract 129 | 16,678
Cardiovascular System 122 | 15,192

Target Family

Non-IDG 85 | 12,091
Enzyme 32 | 4,145
Transcription Factor 17 | 1,400
Kinase 5 | 634
Ion Channel 3 | 344
Epigenetic 2 | 242
GPCR 2 | 408
Transporter 2 | 473
oGPCR 1 | 421

GWAS Trait

Tonsillectomy 149 | 149
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Solute carrier family 45 member 4 SLC45A4 Tdark Transporter 0.30 0.50 12
Peroxidasin-like protein PXDNL Tbio Non-IDG -1.10753 14.4 0
Adherens junction-associated protein 1 AJAP1 Tbio Non-IDG -1.20907 21.2 25
Myotubularin-related protein 3 MTMR3 Tbio Enzyme -1.05980 10.7 33
Transient receptor potential cation channel subfamily M member 3 TRPM3 Tchem Ion Channel -2.19236 141.8 121
Glucocorticoid-induced transcript 1 protein GLCCI1 Tbio Non-IDG -1.39326 24.3 158
Calcium-binding protein 7 CABP7 Tdark Non-IDG -0.42500 3.25 79
Suppression of tumorigenicity 5 protein ST5 Tbio Non-IDG -2.14294 141.9 161
Krueppel-like factor 13 KLF13 Tbio Transcription Factor -1.40009 27.3 111