Development Level

Tbio 38 | 11,445
Tdark 8 | 6,588
Tchem 6 | 1,598
Tclin 2 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal bone structure 3 | 187
preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
abnormal spleen morphology 2 | 55
decreased lean body mass 2 | 135
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased total body fat amoun... 2 | 134
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal placenta vasculature 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased anxiety-related resp... 1 | 12
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating lactate ... 1 | 3
decreased heart left ventricle... 1 | 28
decreased lymphocyte cell numb... 1 | 83
decreased respiratory quotient 1 | 16
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
enlarged testis 1 | 6
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
male infertility 1 | 123
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
scaly skin 1 | 4
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
syndactyly 1 | 23

Disease

Carcinoma 36 | 11,493
ovarian cancer 27 | 8,520
psoriasis 27 | 6,694
lung cancer 24 | 4,740
osteosarcoma 23 | 7,950
glioblastoma 21 | 5,792
medulloblastoma, large-cell 19 | 6,241
group 3 medulloblastoma 16 | 4,104
atypical teratoid / rhabdoid tumor 15 | 5,112
non-small cell lung cancer 14 | 2,890
Cancer 13 | 2,499
lung carcinoma 13 | 2,843
Breast cancer 12 | 3,578
invasive ductal carcinoma 12 | 2,951
malignant mesothelioma 11 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
primitive neuroectodermal tumor 10 | 3,035
adult high grade glioma 9 | 3,801
ependymoma 9 | 4,679
subependymal giant cell astrocytoma 9 | 2,287
Astrocytoma, Pilocytic 8 | 3,081
Kidney cancer 8 | 2,613
Testicular Germ Cell Tumor 8 | 14
Testicular cancer 8 | 25
adrenocortical carcinoma 8 | 1,428
colon cancer 8 | 1,478
cystic fibrosis 8 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
ductal carcinoma in situ 7 | 1,745
group 4 medulloblastoma 7 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung adenocarcinoma 7 | 2,716
pancreatic cancer 7 | 2,398
pediatric high grade glioma 7 | 1,064
pituitary cancer 7 | 1,972
ulcerative colitis 7 | 1,819
interstitial cystitis 6 | 2,312
oligodendroglioma 6 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Pick disease 5 | 1,894
Prostatic Neoplasms 5 | 495
active ulcerative colitis 5 | 764
acute myeloid leukemia 5 | 783
astrocytic glioma 5 | 2,597
spina bifida 5 | 1,074
Acquired metabolic disease 4 | 336
Endometriosis 4 | 540
Prostate cancer 4 | 175
Schizophrenia 4 | 1,160
Short stature 4 | 531
Small head 4 | 374
cutaneous lupus erythematosus 4 | 1,057
nasopharyngeal carcinoma 4 | 1,058
primary Sjogren syndrome 4 | 735
progressive supranuclear palsy 4 | 676
Alcoholic Intoxication, Chronic 3 | 289
Anemia 3 | 365
Atopic dermatitis 3 | 952
Bilateral fifth finger clinodactyly 3 | 110
Bipolar Disorder 3 | 666
Cryptorchidism 3 | 296
Curvature of little finger 3 | 110
Fetal Growth Retardation 3 | 189
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Male infertility 3 | 206
Melanoma 3 | 711
Multiple myeloma 3 | 1,332
Neoplasms, Germ Cell and Embryonal 3 | 15
Testicular Neoplasms 3 | 6
Thrombocytopenia 3 | 197
active Crohn's disease 3 | 922
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
juvenile dermatomyositis 3 | 1,187
mucosa-associated lymphoid tissue lymphoma 3 | 484
posterior fossa group A ependymoma 3 | 468
tuberculosis 3 | 2,010
Adenoma 2 | 167
Alzheimer's disease 2 | 658
Atrial Fibrillation 2 | 124
Cerebral atrophy 2 | 178
Coronary artery disease 2 | 268
Disease Progression 2 | 136
Duchenne muscular dystrophy 2 | 601
Endometrial cancer 2 | 311
Epilepsy 2 | 792
Kidney disease 2 | 430
Liver cancer 2 | 604
Major Depressive Disorder 2 | 301
Motor neuron disease 2 | 49
Myocardial Ischemia 2 | 169
Polycystic ovary syndrome 2 | 360
Refractive error 2 | 50
Seizures 2 | 596
Unipolar Depression 2 | 250
Waldenstrons macroglobulinemia 2 | 765
atypical teratoid/rhabdoid tumor 2 | 357
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Endocrine System 52 | 18,159
Digestive Tract 51 | 17,369
Female tissues 50 | 17,400
Male tissues 50 | 17,142
Blood and immune system 49 | 16,909
Liver and Pancreas 49 | 16,750
Skin and soft tissues 49 | 17,230
Respiratory system 48 | 16,393
Urinary Tract 48 | 16,678
Nervous System 47 | 16,725
Cardiovascular System 43 | 15,192

Target Family

Non-IDG 25 | 12,091
Transcription Factor 12 | 1,400
Enzyme 10 | 4,145
Kinase 4 | 634
GPCR 1 | 408
TF/Epigenetic 1 | 38
Transporter 1 | 473

GWAS Trait

Testicular germ cell tumor 54 | 54
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Doublesex- and mab-3-related transcription factor 1 DMRT1 Tbio Transcription Factor -2.31269 210.5 197
Condensin-2 complex subunit G2 NCAPG2 Tbio Non-IDG -0.75957 5.48 110
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
Protogenin PRTG Tbio Non-IDG -1.17706 16.5 36
Zinc finger protein 638 ZNF638 Tbio Non-IDG -0.68946 6.04 67
Psoriasis susceptibility 1 candidate gene 1 protein PSORS1C1 Tbio Non-IDG -0.99481 11.0 63
Uncharacterized protein KIAA1551 KIAA1551 Tdark Non-IDG -0.49946 2.76 22
Zinc finger protein 257 ZNF257 Tdark Transcription Factor -0.06695 1.13 37
Zinc finger protein 64 homolog, isoforms 3 and 4 ZFP64 Tbio Non-IDG -0.90182 13.5 153
Probable G-protein coupled receptor 160 GPR160 Tbio GPCR -0.79679 5.05 178