Development Level

Tbio 11 | 11,445

IMPC Phenotype

abnormal bone structure 2 | 187
abnormal locomotor behavior 2 | 24
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
decreased total body fat amoun... 2 | 207
enlarged stomach 2 | 2
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
increased red blood cell distr... 2 | 34
increased total body fat amoun... 2 | 134
short tibia 2 | 97
small thymus 2 | 16
tremors 2 | 39

Disease

Carcinoma 10 | 11,493
Kidney cancer 9 | 2,613
psoriasis 8 | 6,694
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
Liver cancer 6 | 604
atypical teratoid / rhabdoid tumor 6 | 5,112
Breast cancer 5 | 3,578
Skin cancer 5 | 469
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
pituitary cancer 5 | 1,972
Endometrial cancer 4 | 311
Melanoma 4 | 711
interstitial cystitis 4 | 2,312
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Astrocytoma, Pilocytic 3 | 3,081
Autistic Disorder 3 | 364
Epilepsy 3 | 792
Intellectual disability 3 | 1,016
Large intestine cancer 3 | 126
Obesity 3 | 678
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
pancreatic cancer 3 | 2,398
Alzheimer's disease 2 | 658
Asperger syndrome 2 | 37
Autism spectrum disorder 2 | 101
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Cancer 2 | 2,499
Colorectal Neoplasms 2 | 243
Constipation 2 | 181
Dyschezia 2 | 135
Gilles de la Tourette syndrome 2 | 47
Globe disease 2 | 67
Liver Cirrhosis, Experimental 2 | 769
Motor neuron disease 2 | 49
Muscle hypotonia 2 | 571
Nicotine dependence 2 | 54
Pitt-Hopkins syndrome 2 | 20
Pitt-Hopkins-Like Syndrome 2 2 | 2
Rheumatoid arthritis 2 | 1,191
Systemic lupus erythematosus 2 | 194
Vascular disease 2 | 319
Vitiligo 2 | 73
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung carcinoma 2 | 317
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Arachnodactyly 1 | 49
Atrial Septal Defects 1 | 85
Attention Deficit Disorder with Hyperactivity 1 | 21
Breast Neoplasms 1 | 445
Cataract 8 multiple types 1 | 33
Chromosome 9p deletion syndrome 1 | 13
Common variable immunodeficiency 1 | 101
Craniofacial Abnormalities 1 | 151
Drooling 1 | 27
Fatigue 1 | 182
Filariasis 1 | 21
Generalized osteopenia 1 | 99
Hearing Loss 1 | 17
Joint stiffness 1 | 84
Language Development Disorders 1 | 11
Lymphoid leukemia 1 | 160
Macular degeneration 1 | 65
Mammary Neoplasms 1 | 425
Mitral valve insufficiency 1 | 49
Nonsyndromic deafness 1 | 142
Osteopenia 1 | 99
Protrusion of tongue 1 | 11
Rectal neoplasm 1 | 6
Sialorrhea 1 | 28
Skin Diseases 1 | 71
Thyrotoxicosis 1 | 38
facioscapulohumeral dystrophy 1 | 288
hearing impairment 1 | 199

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 8 | 12,091
Enzyme 2 | 4,145
GPCR 1 | 408

GWAS Trait

Temperament 11 | 11
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Thyroglobulin TG Tbio Non-IDG -3.88676 7423.9 1081
Cell adhesion molecule 2 CADM2 Tbio Non-IDG -1.29213 17.5 144
Fibrillin-2 FBN2 Tbio Non-IDG -2.46578 287.6 123
Neurexin-1-beta NRXN1 Tbio Non-IDG -1.88807 125.1 174
Amyloid-beta A4 precursor protein-binding family A member 2 APBA2 Tbio Non-IDG -1.60681 41.4 135
Protein Mis18-alpha MIS18A Tbio Non-IDG -2.14017 104.5 47
Methionine-R-sulfoxide reductase B3 MSRB3 Tbio Enzyme -1.27275 18.8 55
Adhesion G protein-coupled receptor L2 ADGRL2 Tbio GPCR -1.96075 87.1 88
Src-like-adapter SLA Tbio Non-IDG -1.56148 36.3 87