Development Level

Tbio 101 | 11,445
Tdark 31 | 6,588
Tchem 16 | 1,598
Tclin 11 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

enlarged heart 6 | 210
preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 6 | 499
abnormal heart morphology 4 | 162
abnormal seminal vesicle morph... 4 | 114
increased circulating sodium l... 3 | 71
small superior vagus ganglion 3 | 74
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
abnormal pancreas morphology 2 | 13
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased circulating glucose ... 2 | 126
decreased hemoglobin content 2 | 68
decreased lymphocyte cell numb... 2 | 83
enlarged uterus 2 | 11
hydrometra 2 | 53
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
increased erythrocyte cell num... 2 | 39
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased monocyte cell number 2 | 63
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal iris morphology 1 | 13
abnormal locomotor behavior 1 | 24
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
pale yolk sac 1 | 25
pallor 1 | 34
short tibia 1 | 97
small kidney 1 | 16
small spleen 1 | 19
vertebral fusion 1 | 23

Disease

Carcinoma 112 | 11,493
ovarian cancer 85 | 8,520
osteosarcoma 81 | 7,950
Systemic lupus erythematosus 66 | 194
psoriasis 64 | 6,694
lung cancer 59 | 4,740
medulloblastoma, large-cell 56 | 6,241
glioblastoma 50 | 5,792
Rheumatoid arthritis 44 | 1,191
atypical teratoid / rhabdoid tumor 39 | 5,112
lung carcinoma 39 | 2,843
adult high grade glioma 38 | 3,801
invasive ductal carcinoma 37 | 2,951
malignant mesothelioma 37 | 3,232
Cancer 36 | 2,499
ependymoma 36 | 4,679
non-small cell lung cancer 35 | 2,890
subependymal giant cell astrocytoma 34 | 2,287
ulcerative colitis 34 | 1,819
Astrocytoma, Pilocytic 33 | 3,081
Breast cancer 33 | 3,578
Kidney cancer 32 | 2,613
interstitial cystitis 31 | 2,312
group 3 medulloblastoma 30 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
lung adenocarcinoma 29 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
primitive neuroectodermal tumor 27 | 3,035
tuberculosis 27 | 2,010
cystic fibrosis 26 | 1,696
Lupus Erythematosus, Systemic 25 | 67
Multiple Sclerosis 24 | 540
pancreatic cancer 24 | 2,398
diabetes mellitus 23 | 1,728
Crohn's disease 21 | 321
cutaneous lupus erythematosus 21 | 1,057
primary Sjogren syndrome 21 | 735
Pick disease 20 | 1,894
pituitary cancer 20 | 1,972
ductal carcinoma in situ 19 | 1,745
oligodendroglioma 19 | 2,850
Arthritis, Rheumatoid 18 | 174
Autosomal recessive predisposition 18 | 1,442
breast carcinoma 18 | 1,638
astrocytic glioma 17 | 2,597
juvenile dermatomyositis 17 | 1,187
Hypersensitivity reaction type II disease 15 | 253
Schizophrenia 15 | 1,160
astrocytoma 15 | 1,146
adrenocortical carcinoma 14 | 1,428
group 4 medulloblastoma 14 | 1,855
Kidney disease 13 | 430
dermatomyositis 13 | 966
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Connective tissue disease 12 | 62
Type 1 diabetes mellitus 12 | 109
acute quadriplegic myopathy 12 | 1,158
colon cancer 12 | 1,478
primary pancreatic ductal adenocarcinoma 12 | 1,109
Fever 11 | 138
Multiple myeloma 11 | 1,332
Systemic scleroderma 11 | 60
nasopharyngeal carcinoma 11 | 1,058
non primary Sjogren syndrome sicca 11 | 891
Alzheimer's disease 10 | 658
Anemia 10 | 365
Atopic dermatitis 10 | 952
Liver Cirrhosis, Experimental 10 | 769
Liver cancer 10 | 604
Melanoma 10 | 711
Obesity 10 | 678
esophageal adenocarcinoma 10 | 737
Arthralgia 9 | 90
Arthritis 9 | 290
Autistic Disorder 9 | 364
Duchenne muscular dystrophy 9 | 601
Epilepsy 9 | 792
Muscle hypotonia 9 | 571
Waldenstrons macroglobulinemia 9 | 765
active ulcerative colitis 9 | 764
gastric carcinoma 9 | 807
medulloblastoma 9 | 720
mucosa-associated lymphoid tissue lymphoma 9 | 484
pediatric high grade glioma 9 | 1,064
Acquired metabolic disease 8 | 336
Asthma 8 | 385
Celiac disease 8 | 116
Fatigue 8 | 182
Hepatomegaly 8 | 285
Intellectual disability 8 | 1,016
Liver carcinoma 8 | 240
Nausea and vomiting 8 | 97
Primary biliary cirrhosis 8 | 51
Prostatic Neoplasms 8 | 495
Seizures 8 | 596
Sjogren's syndrome 8 | 26
Vitiligo 8 | 73
active Crohn's disease 8 | 922
spina bifida 8 | 1,074

Tissue

Endocrine System 152 | 18,159
Female tissues 150 | 17,400
Male tissues 150 | 17,142
Urinary Tract 150 | 16,678
Blood and immune system 149 | 16,909
Digestive Tract 149 | 17,369
Nervous System 149 | 16,725
Skin and soft tissues 149 | 17,230
Liver and Pancreas 147 | 16,750
Respiratory system 146 | 16,393
Cardiovascular System 135 | 15,192

Target Family

Non-IDG 87 | 12,091
Enzyme 25 | 4,145
Transcription Factor 20 | 1,400
Kinase 11 | 634
Transporter 7 | 473
Epigenetic 2 | 242
GPCR 2 | 408
Ion Channel 2 | 344
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38
oGPCR 1 | 421

GWAS Trait

Systemic lupus erythematosus 159 | 159
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein Helios IKZF2 Tbio Transcription Factor -1.26324 15.8 221
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
Solute carrier family 12 member 1 SLC12A1 Tclin Transporter -2.37125 226.3 178
Mitochondrial ribosome-associated GTPase 1 MTG1 Tdark Enzyme -0.54103 1.89 89
Transportin-3 TNPO3 Tbio Non-IDG -1.74707 55.2 105
Putative C->U-editing enzyme APOBEC-4 APOBEC4 Tdark Non-IDG -0.53411 2.24 183
Interferon regulatory factor 5 IRF5 Tbio Transcription Factor -2.33923 241.0 400
Lysosomal-trafficking regulator LYST Tbio Non-IDG -1.96473 92.5 15
Glycolipid transfer protein domain-containing protein 2 GLTPD2 Tdark Non-IDG 0.00000 48