Development Level

Tbio 2 | 11,178
Tclin 2 | 612

IMPC Phenotype

abnormal coat-hair pigmentatio... 1 | 64
abnormal skin morphology 1 | 50
decreased eosinophil cell numb... 1 | 24
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
enlarged heart 1 | 210

Disease

Achromasia 2 | 11
Acute contagious conjunctivitis 2 | 7
Albinism 2 | 11
Basal cell carcinoma 2 | 54
Carcinoma 2 | 11,192
Carcinoma, Basal Cell 2 | 28
Freckles 2 | 33
Low Vision 2 | 167
Melanocytic nevus 2 | 43
Melanoma 2 | 689
Nystagmus 2 | 309
Oculocutaneous albinism 2 | 29
Optic nerve abnormalities 2 | 5
Photodysphoria 2 | 117
Photophobia 2 | 117
Pigmentary iris degeneration 2 | 20
Skin cancer 2 | 451
Strabismus 2 | 265
Visual Impairment 2 | 167
Vitiligo 2 | 71
lung adenocarcinoma 2 | 2,627
lung cancer 2 | 4,607
psoriasis 2 | 6,514
ALBINISM, OCULAR, WITH LATE-ONSET SENSORINEURAL DEAFNESS (disorder) 1 | 2
ALBINISM, OCULAR, WITH SENSORINEURAL DEAFNESS (disorder) 1 | 2
ALBINISM, OCULOCUTANEOUS, TYPE IB (disorder) 1 | 1
Abnormal visual evoked potential 1 | 25
Abnormality of retinal pigmentation 1 | 109
Abnormality of the lymphatic system 1 | 13
Acute Kidney Tubular Necrosis 1 | 6
Adult T-Cell Lymphoma/Leukemia 1 | 29
Albinism, Ocular 1 | 8
Albinism, Oculocutaneous 1 | 2
Albinism, Oculocutaneous, Type 2 1 | 2
Angiomyolipoma 1 | 17
Astigmatism 1 | 54
CMM1 1 | 5
Celiac disease 1 | 110
Central nervous system disease 1 | 10
Chagas disease 1 | 38
Chediak-Higashi syndrome 1 | 26
Congenital melanocytic nevus 1 | 2
Dry skin 1 | 74
Dull foveal reflex 1 | 9
Erythropoietic protoporphyria 1 | 15
Foveal hypoplasia (finding) 1 | 9
GIANT PIGMENTED HAIRY NEVUS 1 | 2
Gaucher disease type 3 1 | 65
Generalized hirsutism 1 | 33
Giant melanosomes in melanocytes 1 | 4
Hair hypopigmentation 1 | 12
Hair shaft abnormalities 1 | 30
Hepatorenal syndrome 1 | 6
Hereditary Melanoma 1 | 12
Hermansky-Pudlak syndrome 1 | 42
Hyperalgesia 1 | 80
Hyperopia 1 | 68
Hypopigmentation disorder 1 | 24
Kidney cortex necrosis 1 | 2
Leukemia, Lymphocytic, Chronic, B-Cell 1 | 33
Leukemia-Lymphoma, Adult T-Cell 1 | 29
Lymphatic Diseases 1 | 13
Lymphoid leukemia 1 | 156
Lymphoma, T-Cell, Cutaneous 1 | 22
MELANOMA, CUTANEOUS MALIGNANT, 1 1 | 13
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 5 1 | 1
Macular degeneration 1 | 64
Malignant ciliary body melanoma 1 | 1
Melanocytic Nevus Syndrome, Congenital 1 | 3
Microphthalmia 1 | 72
Multiple lentigines 1 | 10
Myopia 1 | 175
Nevus 1 | 19
Noncancerous mole 1 | 28
Nonorganic psychosis 1 | 83
Ocular melanoma 1 | 4
Oculocutaneous albinism type 1 1 | 1
Oculocutaneous albinism type 2 1 | 2
Optic nerve dysplasia 1 | 6
Piebaldism 1 | 15
Prenatal onset 1 | 137
Protein-Losing Enteropathies 1 | 4
Reduced visual acuity 1 | 60
Retinal depigmentation 1 | 12
Retinal pigment epithelial abnormality 1 | 109
Senile lentigo 1 | 10
Sensorineural Hearing Loss (disorder) 1 | 281
Skin Neoplasms 1 | 67
Squamous cell carcinoma 1 | 125
Tietz syndrome 1 | 6
Uveal melanoma 1 | 20
Vestibular hypofunction 1 | 7
Waardenburg's syndrome 1 | 16
White hair 1 | 7
Xerosis 1 | 74
blue iris (physical finding) 1 | 17
familial melanoma 1 | 10
hair abnormalities (non-specific) 1 | 30
inflammatory breast cancer 1 | 272
permanent atrial fibrillation 1 | 42

Tissue

Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Skin and soft tissues 4 | 17,230
Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Urinary Tract 3 | 16,678

Target Family

Enzyme 1 | 4,145
GPCR 1 | 408
Non-IDG 1 | 12,091
Transcription Factor 1 | 1,400

GWAS Trait

Sunburns 4 | 4
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interferon regulatory factor 4 IRF4 Tbio Transcription Factor -2.54787 365.3 532
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Tyrosinase TYR Tclin Enzyme -3.32888 2021.2 494
Neurotrimin NTM Tbio Non-IDG -1.70699 47.1 106