Development Level

Tbio 84 | 11,651
Tchem 19 | 1,388
Tdark 17 | 6,593
Tclin 9 | 612

Collection

Kinase: IDG Consortium (Target... 3 | 125
RFA-RM-18-021 3 | 328

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 5 | 499
decreased circulating glucose ... 4 | 126
increased prepulse inhibition 4 | 32
abnormal embryo size 3 | 220
decreased body weight 3 | 161
decreased circulating chloride... 3 | 30
decreased lean body mass 3 | 135
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
thrombocytopenia 3 | 56
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
anophthalmia 2 | 33
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hyperactivity 2 | 148
increased circulating alanine ... 2 | 13
increased circulating calcium ... 2 | 34
increased circulating total pr... 2 | 28
increased fasted circulating g... 2 | 76
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
microphthalmia 2 | 26
prenatal lethality prior to he... 2 | 87
small superior vagus ganglion 2 | 74
small testis 2 | 58
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal midbrain development 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic lethality prior to o... 1 | 239
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased B cell number 1 | 9
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased heart rate 1 | 23
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
prenatal lethality 1 | 28
small adrenal glands 1 | 16
small seminal vesicle 1 | 10
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 85 | 11,493
ovarian cancer 75 | 8,520
osteosarcoma 70 | 7,950
psoriasis 56 | 6,694
glioblastoma 54 | 5,792
medulloblastoma, large-cell 52 | 6,241
lung cancer 47 | 4,740
Cancer 41 | 2,499
atypical teratoid / rhabdoid tumor 40 | 5,112
non-small cell lung cancer 40 | 2,890
lung carcinoma 37 | 2,843
ependymoma 36 | 4,679
adult high grade glioma 35 | 3,801
invasive ductal carcinoma 35 | 2,951
pancreatic cancer 33 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,291
Breast cancer 31 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
lung adenocarcinoma 31 | 2,716
tuberculosis 31 | 2,010
Rheumatoid arthritis 30 | 1,191
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,989
group 3 medulloblastoma 29 | 4,104
interstitial cystitis 29 | 2,312
primitive neuroectodermal tumor 29 | 3,035
Astrocytoma, Pilocytic 28 | 3,081
subependymal giant cell astrocytoma 25 | 2,287
ulcerative colitis 25 | 1,819
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
diabetes mellitus 22 | 1,728
Kidney cancer 20 | 2,613
cystic fibrosis 20 | 1,696
group 4 medulloblastoma 20 | 1,855
malignant mesothelioma 20 | 3,232
astrocytic glioma 18 | 2,597
juvenile dermatomyositis 18 | 1,187
cutaneous lupus erythematosus 17 | 1,057
ductal carcinoma in situ 17 | 1,745
primary Sjogren syndrome 17 | 735
breast carcinoma 16 | 1,638
oligodendroglioma 16 | 2,850
pituitary cancer 16 | 1,972
Multiple myeloma 15 | 1,332
Pick disease 15 | 1,894
active Crohn's disease 15 | 922
Waldenstrons macroglobulinemia 14 | 765
dermatomyositis 14 | 966
Autosomal recessive predisposition 13 | 1,442
active ulcerative colitis 13 | 764
colon cancer 13 | 1,478
spina bifida 13 | 1,074
Anemia 12 | 365
Crohn's disease 12 | 321
Type 2 diabetes mellitus 12 | 272
adrenocortical carcinoma 12 | 1,428
esophageal adenocarcinoma 12 | 737
mucosa-associated lymphoid tissue lymphoma 12 | 484
non primary Sjogren syndrome sicca 12 | 891
Acquired metabolic disease 11 | 336
Alzheimer's disease 11 | 658
Coronary artery disease 11 | 268
Intellectual disability 11 | 1,016
acute quadriplegic myopathy 11 | 1,158
Arthritis, Rheumatoid 10 | 174
Asthma 10 | 385
Atherosclerosis 10 | 291
Kidney disease 10 | 430
acute myeloid leukemia 10 | 783
pediatric high grade glioma 10 | 1,064
periodontitis 10 | 293
Chronic Lymphocytic Leukemia 9 | 262
Hepatomegaly 9 | 285
Multiple Sclerosis 9 | 540
Neutropenia 9 | 72
Obesity 9 | 678
Prostatic Neoplasms 9 | 495
primary pancreatic ductal adenocarcinoma 9 | 1,109
Arthritis 8 | 290
Atopic dermatitis 8 | 952
Bipolar Disorder 8 | 666
Diarrhea 8 | 253
Duchenne muscular dystrophy 8 | 601
Dull intelligence 8 | 645
Liver Cirrhosis, Experimental 8 | 769
Low intelligence 8 | 645
Lymphoid leukemia 8 | 160
Melanoma 8 | 711
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Splenomegaly 8 | 190
Thrombocytopenia 8 | 197
medulloblastoma 8 | 720
posterior fossa group A ependymoma 8 | 468
Schizophrenia 7 | 1,160
aldosterone-producing adenoma 7 | 665
astrocytoma 7 | 1,146
chronic rhinosinusitis 7 | 512
gastric cancer 7 | 459
gastric carcinoma 7 | 807

Tissue

Endocrine System 126 | 18,159
Blood and immune system 123 | 16,909
Digestive Tract 123 | 17,369
Female tissues 123 | 17,400
Liver and Pancreas 123 | 16,750
Nervous System 123 | 16,725
Skin and soft tissues 122 | 17,230
Respiratory system 121 | 16,393
Male tissues 120 | 17,142
Urinary Tract 120 | 16,678
Cardiovascular System 118 | 15,192

Target Family

Non-IDG 58 | 12,091
Enzyme 34 | 4,145
Kinase 11 | 634
Transcription Factor 11 | 1,400
GPCR 7 | 408
Transporter 5 | 473
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

GWAS Trait

Sum neutrophil eosinophil coun... 129 | 129
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.52487 33.2 60
AP-4 complex subunit beta-1 AP4B1 Tbio Non-IDG -0.79214 6.23 124
Cyclic AMP-responsive element-binding protein 5 CREB5 Tbio Transcription Factor -0.88055 7.80 164
Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B Tbio Non-IDG -2.61667 619.4 476
26S proteasome non-ATPase regulatory subunit 3 PSMD3 Tbio Enzyme -1.22269 15.9 168
RCC1 and BTB domain-containing protein 1 RCBTB1 Tbio Non-IDG -1.76204 47.7 188
Cyclin-dependent kinase 6 CDK6 Tclin Kinase -2.71197 390.1 730
RNA-binding protein with multiple splicing RBPMS Tbio Non-IDG -2.12771 131.9 266
Single-stranded DNA-binding protein 4 SSBP4 Tdark Non-IDG -0.17609 1.13 55