Development Level

Tbio 13 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal bone structure 4 | 187
increased heart weight 4 | 62
increased startle reflex 4 | 112
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
decreased body weight 1 | 161
decreased circulating glycerol... 1 | 16
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 14 | 11,493
ovarian cancer 12 | 8,520
pancreatic cancer 8 | 2,398
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
psoriasis 7 | 6,694
Kidney cancer 6 | 2,613
Liver cancer 6 | 604
cystic fibrosis 6 | 1,696
lung cancer 6 | 4,740
Astrocytoma, Pilocytic 5 | 3,081
Cancer 5 | 2,499
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
atypical teratoid / rhabdoid tumor 5 | 5,112
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
osteosarcoma 5 | 7,950
pituitary cancer 5 | 1,972
ACTH-secreting pituitary adenoma 4 | 9
Acrodysostosis 4 | 12
Acromegaly 4 | 51
Adenoma 4 | 167
Adrenal gland cancer 4 | 12
Beckwith-Wiedemann syndrome 4 | 44
Biliary tract cancer 4 | 19
Bone cancer 4 | 16
Brachydactyly 4 | 156
Carney complex 4 | 25
Cervix carcinoma 4 | 10
Cushing syndrome due to macronodular adrenal hyperplasia 4 | 5
Cushing's syndrome 4 | 48
DOID:3297 4 | 4
Fibrodysplasia ossificans progressiva 4 | 17
Fibrous dysplasia 4 | 15
Hyperphosphatemia 4 | 32
Hyperthyroidism 4 | 53
Hypoparathyroidism 4 | 41
Hypothyroidism 4 | 122
Kidney disease 4 | 430
McCune Albright syndrome 4 | 19
Mccune-Albright Syndrome 4 | 4
Monostotic fibrous dysplasia 4 | 4
Multiple Endocrine Neoplasia Type 1 4 | 29
Obesity 4 | 678
Ossifying fibroma 4 | 15
Pituitary Adenoma, Growth Hormone-Secreting, 1 4 | 5
Pituitary adenoma 4 | 38
Plummer's disease 4 | 11
Polycystic ovary syndrome 4 | 360
Primary pigmented nodular adrenocortical disease 4 | 13
Progressive osseous heteroplasia 4 | 4
Pseudohypoparathyroidism 4 | 18
Pseudohypoparathyroidism type 1C 4 | 4
Pseudohypoparathyroidism, Type 1A 4 | 4
Pseudohypoparathyroidism, Type 1B 4 | 5
Pseudopseudohypoparathyroidism 4 | 6
Schizophrenia 4 | 1,160
Small intestine cancer 4 | 12
Stomach cancer 4 | 30
Substance Withdrawal Syndrome 4 | 55
Thyroid cancer 4 | 36
chronic rhinosinusitis 4 | 512
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
substance-related disorder 4 | 162
Breast cancer 3 | 3,578
Pick disease 3 | 1,894
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
astrocytoma 3 | 1,146
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Epilepsy 2 | 792
Major Depressive Disorder 2 | 301
Nephrolithiasis 2 | 56
Psychotic Disorders 2 | 151
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
malignant mesothelioma 2 | 3,232
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Respiratory system 15 | 16,393
Urinary Tract 15 | 16,678
Cardiovascular System 14 | 15,192
Nervous System 14 | 16,725
Skin and soft tissues 14 | 17,230

Target Family

Non-IDG 15 | 12,091
GPCR 2 | 408
Enzyme 1 | 4,145

GWAS Trait

Sulfasalazine-induced agranulo... 18 | 18
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
Reticulon-4 receptor-like 1 RTN4RL1 Tbio Non-IDG -0.81334 6.43 92
Maestro heat-like repeat-containing protein family member 6 MROH6 Tdark Non-IDG 0.78 0.05 6
Extracellular sulfatase Sulf-1 SULF1 Tbio Enzyme -1.90276 92.2 61
Protein ALEX GNAS Tbio Non-IDG -2.63356 1389.7 509
5-hydroxytryptamine receptor 5A HTR5A Tchem GPCR -1.67734 48.8 246
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas GNAS Tbio Non-IDG -2.63356 1389.7 509
Transmembrane protein 245 TMEM245 Tdark Non-IDG -0.27107 1.60 31
Oxysterol-binding protein-related protein 3 OSBPL3 Tbio Non-IDG -0.79520 7.14 74
Intraflagellar transport protein 88 homolog IFT88 Tbio Non-IDG -1.92777 74.0 149